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  1. Article ; Online: Asymptomatic Healthcare Worker PCR Screening during SARS-CoV-2 Omicron Surge, Germany, 2022.

    Bertram, Ralph / Hitzl, Wolfgang / Steinmann, Eike / Steinmann, Joerg

    Emerging infectious diseases

    2023  Volume 29, Issue 8, Page(s) 1690–1692

    Abstract: During 2022, a total of 9,515 asymptomatic healthcare workers of a large hospital in Germany underwent SARS-CoV-2 PCR screening twice weekly. Of 398,784 saliva samples, 3,555 (0.89%) were PCR positive (median cycle threshold value 30). Early ... ...

    Abstract During 2022, a total of 9,515 asymptomatic healthcare workers of a large hospital in Germany underwent SARS-CoV-2 PCR screening twice weekly. Of 398,784 saliva samples, 3,555 (0.89%) were PCR positive (median cycle threshold value 30). Early identification of infected healthcare workers can help reduce SARS-CoV-2 transmission in the hospital environment.
    MeSH term(s) Humans ; SARS-CoV-2/genetics ; COVID-19/diagnosis ; COVID-19/epidemiology ; Polymerase Chain Reaction ; Health Personnel ; Germany/epidemiology ; COVID-19 Testing
    Language English
    Publishing date 2023-06-23
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1380686-5
    ISSN 1080-6059 ; 1080-6040
    ISSN (online) 1080-6059
    ISSN 1080-6040
    DOI 10.3201/eid2908.230156
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 4778: Show issues Location:
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  2. Book ; Thesis: T-Lymphozytenfunktion und klinische Transplantation

    Steinmann, Jörg

    In-vitro-Untersuchungen an humanen alloreaktiven T-Lymphozyten

    (Beiträge zur Transplantationsmedizin ; 16)

    1994  

    Author's details vorgelegt von Jörg Steinmann
    Series title Beiträge zur Transplantationsmedizin ; 16
    Collection
    Keywords Graft Rejection / diagnosis ; Graft Survival / immunology ; Immune Tolerance / drug effects ; Immunosuppression ; T-Lymphocytes / immunology ; Immunologic Tests / methods ; Transplantation ; Immuntoleranz ; T-Lymphozyt ; In vitro
    Subject In-vitro-Methode ; Thymus-Lymphozyt ; T-Zelle ; T-Lymphozyt ; Thymozyt ; Immunologische Toleranz ; Verpflanzung ; Organtransplantation ; Organ ; Organverpflanzung
    Language German
    Size 123 S. : Ill., graph. Darst.
    Publisher Pabst
    Publishing place Lengerich u.a.
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Kiel, Univ., Habil.-Schr., 1993
    HBZ-ID HT006334893
    ISBN 3-928057-33-2 ; 978-3-928057-33-2
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    1994 B 1106 order for loan Magazin

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  3. Article ; Online: Establishment of a Novel Short Tandem Repeat Typing Method for Exophiala dermatitidis.

    Zoqi, Hamide / Schmidt, Dirk / Sedlacek, Ludwig / Rath, Peter-Michael / Steinmann, Joerg / Kirchhoff, Lisa

    Mycopathologia

    2024  Volume 189, Issue 1, Page(s) 5

    Abstract: The opportunistic black yeast-like fungus Exophiala dermatitidis frequently colonizes the respiratory tract of cystic fibroses (CF) patients. Additionally, it can cause superficial, systemic, and cerebral forms of phaeohyphomycoses. The objective of this ...

    Abstract The opportunistic black yeast-like fungus Exophiala dermatitidis frequently colonizes the respiratory tract of cystic fibroses (CF) patients. Additionally, it can cause superficial, systemic, and cerebral forms of phaeohyphomycoses. The objective of this study was to develop and apply a microsatellite or short tandem repeat (STR) genotyping scheme for E. dermatitidis. In total, 82 E. dermatitidis isolates from various geographic origins (environmental = 9, CF = 63, invasive isolates = 9, melanin-deficient mutant = 1) were included in this study. After next-generation sequencing of a reference strain and sequence filtering for microsatellites, six STR markers were selected and amplified in two multiplex PCR reactions. The included isolates were discriminated in a genetic cluster analysis using the Pearson algorithm to reveal the relatedness of the isolates. The E. dermatitidis isolates clustered on basis of both, their source and their origin. The invasive isolates from Asia were unrelated to isolates from CF. Nearly all environmental isolates were grouped separately from patients' isolates. The Simpson index was 0.94. In conclusion, we were able to establish a STR genotyping scheme for investigating population genomics of E. dermatitidis.
    MeSH term(s) Humans ; Exophiala/genetics ; Asia ; Cluster Analysis ; Cystic Fibrosis ; Microsatellite Repeats
    Language English
    Publishing date 2024-01-17
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 391081-7
    ISSN 1573-0832 ; 0369-299X ; 0301-486X ; 0027-5530
    ISSN (online) 1573-0832
    ISSN 0369-299X ; 0301-486X ; 0027-5530
    DOI 10.1007/s11046-023-00825-y
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    In stock of ZB MED Cologne/Königswinter

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  4. Conference proceedings: Sinnvolle Diagnostik bei Endophtalmitidien

    Steinmann, Joerg

    2017  , Page(s) 17sac07

    Event/congress Frühjahrstagung der Sektion Antimykotische Chemotherapie 2017; Bonn; Paul-Ehrlich-Gesellschaft für Chemotherapie e.V. (PEG); 2017
    Keywords Medizin, Gesundheit
    Publishing date 2017-03-13
    Publisher German Medical Science GMS Publishing House; Düsseldorf
    Document type Conference proceedings
    DOI 10.3205/17sac07
    Database German Medical Science

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  5. Book ; Thesis: Tierexperimentelle Untersuchungen zur Immunogenität alter und neuer Nahrungsmittelproteine

    Steinmann, Jörg

    1987  

    Author's details vorgelegt von Jörg Steinmann
    Size 1 Mikrofiche : 24x
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Kiel, Univ., Diss., 1987
    Note Mikroreprod. e. Ms. 42 Bl.: graph. Darst.
    HBZ-ID HT003440636
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    1989 MB 97 order for loan Magazin

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  6. Article: Editorial. FFP2-Masken - korrekte Handhabung ist entscheidend

    Steinmann, Jörg / Soyka, M.

    Umweltmedizin, Hygiene, Arbeitsmedizin

    2021  Volume 26, Issue 3, Page(s) 97

    Language German
    Document type Article
    ZDB-ID 2704545-6
    ISSN 2195-9811
    Database Current Contents Medicine

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 4583: Show issues Location:
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  7. Article: Microbiological Non-Culture-Based Methods for Diagnosing Invasive Pulmonary Aspergillosis in ICU Patients.

    Scharmann, Ulrike / Verhasselt, Hedda Luise / Kirchhoff, Lisa / Furnica, Dan-Tiberiu / Steinmann, Joerg / Rath, Peter-Michael

    Diagnostics (Basel, Switzerland)

    2023  Volume 13, Issue 16

    Abstract: The diagnosis of invasive pulmonary aspergillosis (IPA) in intensive care unit (ICU) patients is crucial since most clinical signs are not specific to invasive fungal infections. To detect an IPA, different criteria should be considered. Next to host ... ...

    Abstract The diagnosis of invasive pulmonary aspergillosis (IPA) in intensive care unit (ICU) patients is crucial since most clinical signs are not specific to invasive fungal infections. To detect an IPA, different criteria should be considered. Next to host factors and radiological signs, microbiological criteria should be fulfilled. For microbiological diagnostics, different methods are available. Next to the conventional culture-based approaches like staining and culture, non-culture-based methods can increase sensitivity and improve time-to-result. Besides fungal biomarkers, like galactomannan and (1→3)-β-D-glucan as nonspecific tools, molecular-based methods can also offer detection of resistance determinants. The detection of novel biomarkers or targets is promising. In this review, we evaluate and discuss the value of non-culture-based microbiological methods (galactomannan, (1→3)-β-D-glucan,
    Language English
    Publishing date 2023-08-21
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2662336-5
    ISSN 2075-4418
    ISSN 2075-4418
    DOI 10.3390/diagnostics13162718
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  8. Article ; Online: Stability of pathogens on banknotes and coins: A narrative review.

    Meister, Toni Luise / Kirchhoff, Lisa / Brüggemann, Yannick / Todt, Daniel / Steinmann, Joerg / Steinmann, Eike

    Journal of medical virology

    2023  Volume 95, Issue 12, Page(s) e29312

    Abstract: For the prevention of infectious diseases, knowledge about potential transmission routes is essential. Pathogens can be transmitted directly (i.e. respiratory droplets, hand-to-hand contact) or indirectly via contaminated surfaces (fomites). In ... ...

    Abstract For the prevention of infectious diseases, knowledge about potential transmission routes is essential. Pathogens can be transmitted directly (i.e. respiratory droplets, hand-to-hand contact) or indirectly via contaminated surfaces (fomites). In particular, frequently touched objects/surfaces may serve as transmission vehicles for different clinically relevant bacterial, fungal, and viral pathogens. Banknotes and coins offer ample surface area and are frequently exchanged between individuals. Consequently, many concerns have been raised in the recent past, that banknotes and coins could serve as vectors for the transmission of disease-causing microorganisms. This review summarizes the latest research on the potential of paper currency and coins to serve as sources of pathogenic viral, bacterial, and fungal agents. In contrast to the current perception of banknotes and coins as important transmission vehicles, current evidence suggests, that banknotes and coins do not pose a particular risk of pathogen infection for the public.
    MeSH term(s) Humans ; Numismatics ; Fomites ; Bacteria/genetics
    Language English
    Publishing date 2023-12-15
    Publishing country United States
    Document type Journal Article ; Review ; Research Support, Non-U.S. Gov't
    ZDB-ID 752392-0
    ISSN 1096-9071 ; 0146-6615
    ISSN (online) 1096-9071
    ISSN 0146-6615
    DOI 10.1002/jmv.29312
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    Zs.A 1320: Show issues Location:
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  9. Article: Overview of Commercially Available PCR Assays for the Detection of

    Rath, Peter-Michael / Steinmann, Joerg

    Frontiers in microbiology

    2018  Volume 9, Page(s) 740

    Abstract: Invasive aspergillosis (IA) is a life-threatening infection in immunocompromised patients. Early diagnosis is essential to improve survival. Since the 1990s, attempts for PCR-based diagnosis of IA were made. Progress in the standardization of methods ... ...

    Abstract Invasive aspergillosis (IA) is a life-threatening infection in immunocompromised patients. Early diagnosis is essential to improve survival. Since the 1990s, attempts for PCR-based diagnosis of IA were made. Progress in the standardization of methods enabled the development of commercially available
    Language English
    Publishing date 2018-04-24
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2587354-4
    ISSN 1664-302X
    ISSN 1664-302X
    DOI 10.3389/fmicb.2018.00740
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  10. Article ; Online: The Heat Stability of Hepatitis B Virus: A Chronological Review From Human Volunteers and Chimpanzees to Cell Culture Model Systems.

    Steinmann, Jochen / Steinmann, Joerg / Steinmann, Eike

    Frontiers in cellular and infection microbiology

    2020  Volume 10, Page(s) 32

    Abstract: During the World War II jaundice and hepatitis in the US army were observed after vaccination with the yellow fever vaccine containing human plasma for stabilization. This led to first heat experiments with volunteers without knowledge of the causative ... ...

    Abstract During the World War II jaundice and hepatitis in the US army were observed after vaccination with the yellow fever vaccine containing human plasma for stabilization. This led to first heat experiments with volunteers without knowledge of the causative agents. Finally, experiments of human serum with volunteers and chimpanzees led to the conclusion that the hepatitis B virus (HBV) which had been identified as the responsible agent of the contamination of the vaccine, could not be inactivated at 98°C after 1 min, whereas 2 min in two chimpanzees were enough. Meanwhile, a cell culture system became available showing that 2 min exposure time is not enough depending on the virus strain used whereas 5 min means complete inactivation of HBV. The great stability of the blood-borne HBV was also of interest in hospital hygiene due to the use of moist heat for disinfection of heat-stable medical devices in washer-disinfectants. The requirements for washer-disinfectors and the parameters describing disinfection with moist heat are defined in the EN ISO 15883. In this standard, the efficacy of this thermal disinfection is described by the A
    MeSH term(s) Animals ; Cell Culture Techniques ; Disinfection ; Healthy Volunteers ; Hepatitis B virus ; Hot Temperature ; Humans ; Pan troglodytes
    Language English
    Publishing date 2020-02-04
    Publishing country Switzerland
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Review
    ZDB-ID 2619676-1
    ISSN 2235-2988 ; 2235-2988
    ISSN (online) 2235-2988
    ISSN 2235-2988
    DOI 10.3389/fcimb.2020.00032
    Database MEDical Literature Analysis and Retrieval System OnLINE

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