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  1. Article ; Online: Lessons in Communication.

    Steinmetz, Jonathan

    Academic medicine : journal of the Association of American Medical Colleges

    2020  Volume 96, Issue 3, Page(s) 381

    Language English
    Publishing date 2020-11-17
    Publishing country United States
    Document type Journal Article
    ZDB-ID 96192-9
    ISSN 1938-808X ; 1040-2446
    ISSN (online) 1938-808X
    ISSN 1040-2446
    DOI 10.1097/ACM.0000000000003877
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Transforming Our Practice and Making Every Bite Count.

    Jayne Steinmetz, Jasia

    Journal of nutrition education and behavior

    2021  Volume 53, Issue 8, Page(s) 641

    Language English
    Publishing date 2021-08-09
    Publishing country United States
    Document type Editorial
    ISSN 1878-2620
    ISSN (online) 1878-2620
    DOI 10.1016/j.jneb.2021.06.012
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Book ; Thesis: Zur Formulierung und Applikation von Trichoderma harzianum und Gliocladium roseum als Antagonisten bodenbürtiger Schadpilze

    Steinmetz, Joachim

    1994  

    Author's details von Joachim Steinmetz
    Keywords Trichoderma harzianum ; Substrat ; Gliocladium roseum ; Mykose ; Antagonist
    Subject Nährsubstrat ; Zuchtsubstrat ; Widersacher ; Mycosis ; Pilzinfektion ; Pilzkrankheit ; Mycose
    Size 113 S. : Ill., zahlr. graph. Darst.
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Hannover, Univ., Diss., 1994
    Remark AY 17115 ; Abt. Nussallee/Bereichsbibl. ZBMed: AY 17115
    HBZ-ID HT006554443
    Database Catalogue ZB MED Nutrition, Environment, Agriculture

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  4. Article ; Online: GDF15 Contributes to the Regulation of the Mechanosensitive Responses of PdL Fibroblasts through the Modulation of IL-37.

    Steinmetz, Julia / Stemmler, Albert / Hennig, Christoph-Ludwig / Symmank, Judit / Jacobs, Collin

    Dentistry journal

    2024  Volume 12, Issue 2

    Abstract: During orthodontic tooth movement (OTM), areas of compressive and tensile forces are generated in the periodontal ligament (PdL), a mechanoreactive connective tissue between the teeth and alveolar bone. Mechanically stimulated PdL fibroblasts (PdLFs), ... ...

    Abstract During orthodontic tooth movement (OTM), areas of compressive and tensile forces are generated in the periodontal ligament (PdL), a mechanoreactive connective tissue between the teeth and alveolar bone. Mechanically stimulated PdL fibroblasts (PdLFs), the main cell type of PdL, express significantly increased levels of growth differentiation factor 15 (GDF15). In compressed PdL areas, GDF15 plays a fundamental role in modulating relevant OTM processes, including inflammation and osteoclast activation. However, the specific function of this factor in tensile areas has not yet been investigated. Thus, the aim of this study was to investigate the role of GDF15 in the mechanoresponse of human PdLFs (hPdLFs) that were exposed to biaxial tensile forces in vitro. Using siRNA-mediated knockdown experiments, we demonstrated that GDF15 had no impact on the anti-inflammatory force response of elongated hPdLFs. Although the anti-inflammatory markers
    Language English
    Publishing date 2024-02-13
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2681351-8
    ISSN 2304-6767 ; 2304-6767
    ISSN (online) 2304-6767
    ISSN 2304-6767
    DOI 10.3390/dj12020039
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Prolonged duration of action of suxamethonium in pregnant and postpartum patients: A registry study.

    Dalsten, Helene / Crone, Vera / Steinmetz, Jacob / Rosager, Christine L / Rasmussen, Lars S / Vested, Matias

    Acta anaesthesiologica Scandinavica

    2024  

    Abstract: Background: Suxamethonium is hydrolysed by butyrylcholinesterase (BChE) and a low BChE activity can result in a prolonged duration of action of suxamethonium. The BChE activity is reduced during pregnancy and postpartum period by up to 33%. However, it ... ...

    Abstract Background: Suxamethonium is hydrolysed by butyrylcholinesterase (BChE) and a low BChE activity can result in a prolonged duration of action of suxamethonium. The BChE activity is reduced during pregnancy and postpartum period by up to 33%. However, it can also be reduced by mutations in the BChE gene. In this study, we assessed BChE activity and mutations in the BChE gene in pregnant and postpartum patients with prolonged duration of action of suxamethonium. It was hypothesised that at least 30% of patients with a low BChE activity did not have a mutation in the BChE gene.
    Methods: In this registry study we focused on pregnant and postpartum patients with a history of prolonged duration of action of suxamethonium referred to the Danish Cholinesterase Research Unit (DCRU) between March 2007 and January 2023. Primary outcome was the proportion of patients without a mutation among patients with a low BChE activity. Secondary outcomes were the proportion of patients with a low BChE activity and the proportion of patients with a mutation out of the total number of patients.
    Results: A total of 40 patients were included and among patients with a low BChE activity, 6% (95% CI: 1%-21%) did not have a mutation. Out of the total number of included patients referred to the DCRU, 90% (95% CI: 76%-97%) had a mutation and 94% (95% CI: 80%-99%) had a low BChE activity.
    Conclusion: Among pregnant and postpartum patients with a history of prolonged duration of action of suxamethonium and a low BChE activity, 6% did not have a mutation in the BChE gene. Our findings suggest that during pregnancy and postpartum clinically relevant prolonged duration of action of suxamethonium rarely occurs in genotypically normal patients.
    Language English
    Publishing date 2024-03-24
    Publishing country England
    Document type Journal Article
    ZDB-ID 80002-8
    ISSN 1399-6576 ; 0001-5172
    ISSN (online) 1399-6576
    ISSN 0001-5172
    DOI 10.1111/aas.14413
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Book ; Thesis: Experimentelle Untersuchungen am weichbleibenden Unterfütterungskunststoff

    Steinmetz, Jochen

    1991  

    Author's details vorgelegt von Jochen Steinmetz
    Size 2 Mikrofiches : 24x
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Freiburg (Breisgau), Univ., Diss., 1991
    Note Mikroreprod. eines Ms.: 106 Bl. : graph. Darst.
    HBZ-ID HT004202513
    Database Catalogue ZB MED Medicine, Health

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  7. Article ; Online: Break a neck.

    Steinmetz, J / Rasmussen, L S

    Acta anaesthesiologica Scandinavica

    2016  Volume 60, Issue 7, Page(s) 837–838

    MeSH term(s) Cervical Cord/injuries ; Fractures, Bone ; Humans ; Neck Injuries
    Language English
    Publishing date 2016-08
    Publishing country England
    Document type Editorial
    ZDB-ID 80002-8
    ISSN 1399-6576 ; 0001-5172
    ISSN (online) 1399-6576
    ISSN 0001-5172
    DOI 10.1111/aas.12726
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Peri-operative cognitive dysfunction and protection.

    Steinmetz, J / Rasmussen, L S

    Anaesthesia

    2016  Volume 71 Suppl 1, Page(s) 58–63

    Abstract: Cognition may decline after surgery. Postoperative delirium, especially when hyperactive, may be easily recognised, whereas cognitive dysfunction is subtle and can only be detected using neuropsychological tests. The causes for these two conditions are ... ...

    Abstract Cognition may decline after surgery. Postoperative delirium, especially when hyperactive, may be easily recognised, whereas cognitive dysfunction is subtle and can only be detected using neuropsychological tests. The causes for these two conditions are largely unknown, although they share risk factors, the predominant one being age. Ignorance of the causes for postoperative cognitive dysfunction contributes to the difficulty of conducting interventional studies. Postoperative cognitive disorders are associated with increased mortality and permanent disability. Peri-operative interventions can reduce the rate of delirium in the elderly, but in spite of promising findings in animal experiments, no intervention reduces postoperative cognitive dysfunction in humans.
    MeSH term(s) Aged ; Cognition Disorders/physiopathology ; Cognition Disorders/prevention & control ; Delirium/physiopathology ; Delirium/prevention & control ; Humans ; Postoperative Complications/physiopathology ; Postoperative Complications/prevention & control ; Risk Factors
    Language English
    Publishing date 2016-01
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 80033-8
    ISSN 1365-2044 ; 0003-2409
    ISSN (online) 1365-2044
    ISSN 0003-2409
    DOI 10.1111/anae.13308
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Book ; Thesis: Verbleib in der Gemeinde oder Umzug in ein Heim?

    Steinmetz, Jochen

    Eine Analyse der Lebenssituation von alleinstehenden betagten Frauen mit ambulanter bzw. stationärer Versorgung als Beitrag zur Diskussion um mögliche Selektionstendenzen

    (Europäische Hochschulschriften : Reihe 22, Soziologie ; 165)

    1988  

    Author's details Jochen Steinmetz
    Series title Europäische Hochschulschriften : Reihe 22, Soziologie ; 165
    Europäische Hochschulschriften
    Europäische Hochschulschriften ; Reihe 22, Soziologie
    Collection Europäische Hochschulschriften
    Europäische Hochschulschriften ; Reihe 22, Soziologie
    Keywords Hamburg ; Alleinstehende Frau ; Lebensbedingungen ; Stationäre Altenhilfe ; Offene Altenhilfe
    Subject Ambulante Altenhilfe ; Lebenssituation ; Lebensverhältnisse ; Lebenslage ; Lebensumstände ; Allein stehende Frau ; Single-Frau ; Alleinstehende Frauen
    Language German
    Size 118 S. : graph. Darst.
    Publisher Lang
    Publishing place Frankfurt am Main u.a.
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Hamburg, Univ., Diss., 1987
    HBZ-ID HT003190392
    ISBN 3-631-40353-4 ; 978-3-631-40353-2
    Database Catalogue ZB MED Medicine, Health

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  10. Article: Agreement Between Standard and ICD-10-Based Injury Severity Scores.

    Eskesen, Trine O / Sillesen, Martin / Rasmussen, Lars S / Steinmetz, Jacob

    Clinical epidemiology

    2022  Volume 14, Page(s) 201–210

    Abstract: Introduction: Injury Severity Score (ISS) is used to describe anatomical lesions. ISS is traditionally determined through medical record review (standard ISS), which requires specific training and may be time-consuming. An alternative way to obtain ISS ... ...

    Abstract Introduction: Injury Severity Score (ISS) is used to describe anatomical lesions. ISS is traditionally determined through medical record review (standard ISS), which requires specific training and may be time-consuming. An alternative way to obtain ISS is by use of ICD-9/10 injury diagnoses, and several conversion tools exist. We sought to evaluate the agreement between standard ISS and ISS obtained with two tools converting ICD-10 diagnoses.
    Methods: Our cohort consisted of trauma patients ≥18 years admitted to Rigshospitalet between 1999 and 2016. The included patients had standard ISS recorded in the Trauma Audit and Research Network (TARN) database (ISS-TARN), and ICD-10 injury diagnoses for the trauma contact were recorded in the Danish National Patient Registry. We used the tools ICDPIC-R and ICD-AIS map to calculate ISS based on ICD-10 diagnoses. ICDPIC-R provided two ISSs: ISS-TQIP and ISS-NIS. The ICD-AIS map resulted in one ISS: ISS-map. The ISS-TARN was compared to the conversion tool ISSs using Bland-Altman plots. The agreement between ISS-TARN and the conversion tool ISSs for ISS above 15 was assessed using kappa statistics (κ).
    Results: We included 4308 trauma patients. The median age was 44 years, 70% were male, and 92% had a blunt injury mechanism. The median ISS-TARN was 16 [IQR: 9-25], and the median conversion tool ISSs were 10 [2-25] (ISS-TQIP), 17 [5-26] (ISS-NIS), and 9 [4-16] (ISS-map). The Bland-Altman plots all showed increasing difference in ISS with increasing mean ISS. Bias ranged from -7.3 to 1.1 and limits of agreement ranged between -28.0 and 25.7. The agreement for ISS above 15 was fair to moderate (κ = 0.43 (ISS-TQIP), 0.44 (ISS-NIS), and 0.29 (ISS-map)).
    Conclusion: Using ICDPIC-R or ICD-AIS map to determine ISS is feasible, but limits of agreement were unacceptably wide. The agreement between ISS-TARN and ICDPIC-R was moderate for ISS above 15.
    Language English
    Publishing date 2022-02-18
    Publishing country New Zealand
    Document type Journal Article
    ZDB-ID 2494772-6
    ISSN 1179-1349
    ISSN 1179-1349
    DOI 10.2147/CLEP.S344302
    Database MEDical Literature Analysis and Retrieval System OnLINE

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