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  1. Article ; Online: England Is Handing out E-Cigarettes: Is the "Swap to Stop" Tobacco Control Scheme Harm Reduction or Harm Production?

    Lang, Adam Edward / Kathuria, Hasmeena / Braillon, Alain / Ewart, Gary / Dagli, Elif / Stepp, Evan L / Galiatsatos, Panagis / Deepak, Janaki / Jordt, Sven E / Hayes, Don

    American journal of respiratory and critical care medicine

    2023  Volume 208, Issue 10, Page(s) 1024–1025

    MeSH term(s) Humans ; Electronic Nicotine Delivery Systems ; Harm Reduction ; Tobacco Control ; Tobacco Products ; England
    Language English
    Publishing date 2023-09-05
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1180953-x
    ISSN 1535-4970 ; 0003-0805 ; 1073-449X
    ISSN (online) 1535-4970
    ISSN 0003-0805 ; 1073-449X
    DOI 10.1164/rccm.202308-1354VP
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

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  2. Article ; Online: Determinants of lung volumes in chronic spinal cord injury.

    Stepp, Evan L / Brown, Robert / Tun, Carlos G / Gagnon, David R / Jain, Nitin B / Garshick, Eric

    Archives of physical medicine and rehabilitation

    2008  Volume 89, Issue 8, Page(s) 1499–1506

    Abstract: Objective: To characterize determinants of lung volumes in chronic spinal cord injury (SCI).: Design: Cross-sectional.: Setting: VA Boston Healthcare System.: Participants: White men (N=330) with chronic SCI.: Interventions: Not applicable.!# ...

    Abstract Objective: To characterize determinants of lung volumes in chronic spinal cord injury (SCI).
    Design: Cross-sectional.
    Setting: VA Boston Healthcare System.
    Participants: White men (N=330) with chronic SCI.
    Interventions: Not applicable.
    Main outcome measures: Questionnaire responses and measurements of lung volumes.
    Results: Adjusted for SCI severity and stature, greater body mass index (BMI) was associated (all P<.05) with lower total lung capacity (TLC) (-38.7 mL x kg(-1) x m(-2)), functional residual capacity (FRC) (-73.9 mL x kg(-1) x m(-2)), residual volume (RV) (-40.4 mL x kg(-1) x m(-2)), and expiratory reserve volume (ERV) (-32.2 mL x kg(-1) x m(-2)). The effect of BMI on RV was most pronounced in quadriplegia (-72 mL x kg(-1) x m(-2)). Lifetime smoking was associated with a greater FRC (5.3 mL/pack-year) and RV (3.1 mL/pack-years). The effects of lifetime smoking were also greatest in quadriplegia (11 mL/pack-year for FRC; 7.8 mL/pack-year for RV). Time since injury, independent of age, was associated with a decrease in TLC, FRC, ERV, and RV (P<.05). Age was not a predictor of TLC once time since injury was considered.
    Conclusions: Determinants of FRC, TLC, ERV, and RV in chronic SCI include factors related and unrelated to SCI. The mechanisms remain to be determined but likely involve the elastic properties and muscle function of the respiratory system and perhaps the effects of systemic inflammation related to adiposity. Addressing modifiable factors such as obesity, muscle stiffness, and smoking may improve respiratory morbidity and mortality in SCI by improving pulmonary function.
    MeSH term(s) Body Mass Index ; Boston/epidemiology ; Chronic Disease ; Comorbidity ; Cross-Sectional Studies ; Forced Expiratory Volume ; Humans ; Lung Volume Measurements ; Male ; Middle Aged ; Multivariate Analysis ; Obesity/epidemiology ; Respiratory Function Tests/statistics & numerical data ; Smoking/epidemiology ; Spinal Cord Injuries/epidemiology ; Spinal Cord Injuries/physiopathology ; Total Lung Capacity
    Language English
    Publishing date 2008-07-12
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, U.S. Gov't, Non-P.H.S.
    ZDB-ID 80057-0
    ISSN 1532-821X ; 0003-9993
    ISSN (online) 1532-821X
    ISSN 0003-9993
    DOI 10.1016/j.apmr.2008.02.018
    Database MEDical Literature Analysis and Retrieval System OnLINE

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