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  1. Book: Die Lebertransplantation

    Sterneck, Martina

    Informationen für Patienten und Angehörige

    2013  

    Author's details Martina Sterneck
    Language German
    Size 116 S. : Ill., graph. Darst., 210 mm x 148 mm
    Edition 5., überarb. Aufl.
    Publisher Pabst Science Publ
    Publishing place Lengerich
    Publishing country Germany
    Document type Book
    HBZ-ID HT018104035
    ISBN 978-3-89967-885-7 ; 3-89967-885-0
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2009 A 10676 order for loan Magazin

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  2. Book: Die Lebertransplantation

    Sterneck, Martina

    Informationsbroschüre für Patienten und Angehörige

    2008  

    Author's details Martina Sterneck
    Keywords Lebertransplantation
    Subject Leber
    Subject code 617.55620592
    Language German
    Size 122 S. : Ill., 21 cm, 184 gr.
    Edition 4., überarb. Aufl.
    Publisher Pabst
    Publishing place Lengerich u.a.
    Publishing country Germany
    Document type Book
    Note Früher mehrbd. begrenztes Werk
    HBZ-ID HT015859476
    ISBN 978-3-89967-518-4 ; 3-89967-518-5
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2007 A 6675 order for loan Magazin

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  3. Book ; Online ; Thesis: Langzeitkomplikationen, Therapieadhärenz und Lebensqualität von lebertransplantierten Erwachsenen nach der Transition in die adulte Medizin

    Lund, Louisa Katharina Verfasser] / [Sterneck, Martina [Akademischer Betreuer]

    2023  

    Author's details Louisa Katharina Lund ; Betreuer: Martina Sterneck
    Keywords Medizin, Gesundheit ; Medicine, Health
    Subject code sg610
    Language Multiple languages
    Publisher Staats- und Universitätsbibliothek Hamburg Carl von Ossietzky
    Publishing place Hamburg
    Document type Book ; Online ; Thesis
    Database Digital theses on the web

    Full text online

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  4. Book ; Thesis: Polymorphismus von hypophysärem Follitropin (hFSH) beim Menschen

    Sterneck, Martina

    1987  

    Keywords FSH / chemistry ; Isoelectric Point
    Size 106 S. : Ill., graph. Darst.
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Hamburg, Univ., Diss., 1988
    HBZ-ID HT003595921
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    90 D 1660 order for loan Magazin

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  5. Book ; Online ; Thesis: Assessment of Alcohol Consumption in Outpatients with Non-alcoholic Fatty Liver Disease

    Rodriguez Lago, Maria Verfasser] / [Sterneck, Martina [Akademischer Betreuer]

    2022  

    Author's details Maria Rodriguez Lago ; Betreuer: Martina Sterneck
    Keywords Medizin, Gesundheit ; Medicine, Health
    Subject code sg610
    Language English
    Publisher Staats- und Universitätsbibliothek Hamburg Carl von Ossietzky
    Publishing place Hamburg
    Document type Book ; Online ; Thesis
    Database Digital theses on the web

    Full text online

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  6. Article ; Online: Long-term Outcome of Pediatric Liver Transplant Recipients Who Have Reached Adulthood: A Single-center Experience.

    Lund, Louisa Katharina / Grabhorn, Enke Freya / Rüther, Darius / Buchholz, Angela / Lang, Melanie / Herden, Uta / Fischer, Lutz / Sterneck, Martina

    Transplantation

    2023  Volume 107, Issue 8, Page(s) 1756–1763

    Abstract: Background: As long-term survival of pediatric liver transplant recipients increases, the assessment of physical, psychological, and social well-being becomes more important.: Methods: In this retrospective analysis, 120 young adult patients (age ≥18 ...

    Abstract Background: As long-term survival of pediatric liver transplant recipients increases, the assessment of physical, psychological, and social well-being becomes more important.
    Methods: In this retrospective analysis, 120 young adult patients (age ≥18 y) who underwent liver transplantation in childhood were studied. Patients with ideal outcome were defined as patients with perfect graft function, with no complications from the immunosuppressive medication, no late retransplantation, and no steroid treatment. Also, the patients' drug adherence and their psychosocial situation were assessed.
    Results: After a median follow-up of 19 y, only 16.7% of the patients (mean age: 26.5 y) were considered patients with ideal outcome. The main reasons precluding ideal outcome were chronic kidney disease (38.3%), elevated liver enzymes (33.3%), and arterial hypertension (31.7%). Ideal outcome decreased over time from 54% to 42%, 26%, and 8% at 10-, 15-, 20-, and 25-y follow-up, respectively. Reduced drug adherence was noted in 24.8% of patients and associated with a significantly higher prevalence of donor-specific antibodies class II ( P  = 0.015), elevated transaminases ( P  = 0.010), and chronic rejection ( P  < 0.001). Also, 15% of patients had a psychiatric disease, mainly depression.
    Conclusions: The morbidity of young adults who underwent liver transplantation as children was high and increased over time. The majority developed complications from immunosuppression or chronic graft dysfunction. More than 1 in 7 patients had a psychiatric disease and 1 in 4 was not perfectly drug adherent. Therefore, immunosuppressive treatment and psychological care should be optimized for these particularly vulnerable patients.
    MeSH term(s) Young Adult ; Child ; Humans ; Adult ; Liver Transplantation/adverse effects ; Retrospective Studies ; Immunosuppressive Agents/adverse effects ; Immunosuppression Therapy ; Liver Diseases ; Graft Rejection/epidemiology ; Graft Rejection/prevention & control ; Transplant Recipients ; Graft Survival
    Chemical Substances Immunosuppressive Agents
    Language English
    Publishing date 2023-02-23
    Publishing country United States
    Document type Journal Article
    ZDB-ID 208424-7
    ISSN 1534-6080 ; 0041-1337
    ISSN (online) 1534-6080
    ISSN 0041-1337
    DOI 10.1097/TP.0000000000004556
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 488: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 509: Show issues

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  7. Book ; Online ; Thesis: Retrospektive Analyse der Wertigkeit der Untersuchungsmethoden von Sarkopenie und Gebrechlichkeit (Frailty) bei Patienten mit einer Leberzirrhose

    Breuer, Miriam Verfasser] / [Sterneck, Martina [Akademischer Betreuer] / Horvatits, Karoline [Akademischer Betreuer]

    2022  

    Author's details Miriam Breuer ; Martina Sterneck, Karoline Horvatits
    Keywords Medizin, Gesundheit ; Medicine, Health
    Subject code sg610
    Language German
    Publisher Staats- und Universitätsbibliothek Hamburg Carl von Ossietzky
    Publishing place Hamburg
    Document type Book ; Online ; Thesis
    Database Digital theses on the web

    Full text online

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  8. Article ; Online: A single-center, open-label, randomized cross-over study to evaluate the pharmacokinetics and bioavailability of once-daily prolonged-release formulations of tacrolimus in de novo liver transplant recipients.

    Herden, Uta / Sterneck, Martina / Buchholz, Bettina M / Achilles, Eike G / Ott, Armin / Fischer, Lutz

    Immunity, inflammation and disease

    2021  Volume 9, Issue 4, Page(s) 1771–1780

    Abstract: Background: The narrow therapeutic window of tacrolimus (Tac) requires intense drug monitoring to achieve adequate efficacy while minimizing dose-related toxicities. Once-daily formulations of Tac (LCP-Tac and PR-Tac) have been recently designed for ... ...

    Abstract Background: The narrow therapeutic window of tacrolimus (Tac) requires intense drug monitoring to achieve adequate efficacy while minimizing dose-related toxicities. Once-daily formulations of Tac (LCP-Tac and PR-Tac) have been recently designed for higher bioavailability and a more consistent exposure over time, as opposed to the twice-daily, administered immediate-release formulation of Tac (IR-Tac).
    Methods: This single-center, open-label, randomized cross-over pharmacokinetic (PK) study compares extended-release LCP-Tac with the prolonged-release formulation of tacrolimus (PR-Tac) in adult de novo liver transplant recipients. Eligible patients were screened and randomized 1:1 to the two treatment arms up to 30 days after liver transplantation. Patients were administered either LCP-Tac or PR-Tac for 14 days followed by another 14-day time interval of the other once-daily Tac medication. A 24hr-PK profile was obtained at the end of each time interval.
    Results: Nine patients (45%) completed the study resulting in a total of 18 Tac PK profiles. Overall, the profile of the mean concentrations indicated a flattened kinetic of LCP-Tac compared to PR-Tac, especially in the first 3 h after drug intake. The average cumulative dose per day to achieve equivalent trough levels was approximately 25% lower for LCP-Tac (8.7 mg) than for PR-Tac (11.7 mg). LCP-Tac resulted in a longer t
    Conclusion: Despite methodological weaknesses that limit the conclusions, we have found a more consistent drug exposure for LCP-Tac in de novo LT recipients. LCP-Tac demonstrated a greater bioavailability compared to PR-Tac.
    MeSH term(s) Adult ; Biological Availability ; Cross-Over Studies ; Drug Administration Schedule ; Humans ; Immunosuppressive Agents ; Liver Transplantation ; Tacrolimus
    Chemical Substances Immunosuppressive Agents ; Tacrolimus (WM0HAQ4WNM)
    Language English
    Publishing date 2021-09-24
    Publishing country England
    Document type Journal Article ; Randomized Controlled Trial ; Research Support, Non-U.S. Gov't
    ZDB-ID 2740382-8
    ISSN 2050-4527 ; 2050-4527
    ISSN (online) 2050-4527
    ISSN 2050-4527
    DOI 10.1002/iid3.537
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: [No title information]

    Tacke, Frank / Cornberg, Markus / Sterneck, Martina / Trebicka, Jonel / Settmacher, Utz / Bechstein, Wolf Otto / Berg, Thomas

    Zeitschrift fur Gastroenterologie

    2022  Volume 60, Issue 11, Page(s) 1678–1698

    Title translation S1-Leitlinie zur Versorgung von Lebertransplantierten während der COVID-19-Pandemie – AWMF-Registernummer: 021-031 – Stand 15. Juni 2022.
    MeSH term(s) Humans ; COVID-19 ; Liver Transplantation ; Pandemics ; Registries ; Risk Factors
    Language German
    Publishing date 2022-11-11
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 201387-3
    ISSN 1439-7803 ; 0172-8504 ; 0044-2771
    ISSN (online) 1439-7803
    ISSN 0172-8504 ; 0044-2771
    DOI 10.1055/a-1934-1989
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 111: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)
    Zs.A 111/X: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  10. Article ; Online: High risk of complications and acute-on-chronic liver failure in cirrhosis patients with acute pancreatitis.

    Vogel, Michael / Ehlken, Hanno / Kluge, Stefan / Roesch, Thomas / Lohse, Ansgar W / Huber, Samuel / Sterneck, Martina / Huebener, Peter

    European journal of internal medicine

    2022  Volume 102, Page(s) 54–62

    Abstract: Background & aims: Acute pancreatitis (AP) is a frequent indication for hospitalization and may present with varying degrees of severity. AP often coincides with hepatic disease, yet the impact of liver cirrhosis (LC) on the course of AP is uncertain, ... ...

    Abstract Background & aims: Acute pancreatitis (AP) is a frequent indication for hospitalization and may present with varying degrees of severity. AP often coincides with hepatic disease, yet the impact of liver cirrhosis (LC) on the course of AP is uncertain, and early identification of patients at risk for complications remains challenging. We aimed to assess the impact of LC on the development of pancreatic and extra-pancreatic complications of AP, and to identify predictors of adverse outcomes in cirrhotic patients.
    Methods: All adult patients with LC and AP (LC-AP, n = 52) admitted to our institution between 01/2011-03/2020 were subjected to a 1:2 matched-pair analysis with patients with AP but without LC (NLC-AP, n = 104).
    Results: At hospital admission, Glasgow-Imrie and Ranson scores as well as markers of systemic inflammation were comparable in LC-AP and NLC-AP patients, and both groups had similar rates of necrotizing AP. Infectious complications were more prevalent, and medical interventions were performed more often and with higher complication rates in LC-AP patients. While only 12.5% of NLC-AP patients developed organ failures, 48% of LC-AP patients developed single (7.7%) or multiple organ failure (40.4%), resulting in 44% of LC-AP patients with acute-on-chronic liver failure (ACLF). Patients with overt portal hypertension were particularly prone for decompensation. Mortality was higher among LC-AP compared to NLC-AP patients (6-month mortality 25% vs. 1.9%, p < 0.001), and SOFA and MELD scores at admission most accurately predicted outcomes in LC-AP.
    Conclusion: Among AP patients, concomitant cirrhosis substantially increases the risk for infections, periprocedural complications, multiorgan failure and death.
    MeSH term(s) Acute Disease ; Acute-On-Chronic Liver Failure/complications ; Adult ; Humans ; Liver Cirrhosis/complications ; Multiple Organ Failure/complications ; Pancreatitis/complications ; Prognosis ; Prospective Studies ; Severity of Illness Index
    Language English
    Publishing date 2022-06-04
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 1038679-8
    ISSN 1879-0828 ; 0953-6205
    ISSN (online) 1879-0828
    ISSN 0953-6205
    DOI 10.1016/j.ejim.2022.05.034
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 2608: Show issues Location:
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