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  1. Article ; Online: The Case for Prevention Research in Adolescent-Onset Mental Illness-Game On!

    Stewart, S Evelyn

    JAMA network open

    2022  Volume 5, Issue 2, Page(s) e2149037

    MeSH term(s) Adolescent ; Health Services Research ; Humans ; Mental Disorders/epidemiology ; Mental Disorders/prevention & control
    Language English
    Publishing date 2022-02-01
    Publishing country United States
    Document type Journal Article ; Comment
    ISSN 2574-3805
    ISSN (online) 2574-3805
    DOI 10.1001/jamanetworkopen.2021.49037
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  2. Article ; Online: Editorial: Expanding Notions of Networks Within Child and Adolescent Psychiatry.

    Stewart, S Evelyn

    Journal of the American Academy of Child and Adolescent Psychiatry

    2020  Volume 59, Issue 7, Page(s) 805–807

    Abstract: Child and adolescent psychiatry trainees are traditionally offered "pearls of wisdom" emphasizing, among other things, the value of collegial peer networks such as that found within the American Academy of Child and Adolescent Psychiatry (AACAP). The ... ...

    Abstract Child and adolescent psychiatry trainees are traditionally offered "pearls of wisdom" emphasizing, among other things, the value of collegial peer networks such as that found within the American Academy of Child and Adolescent Psychiatry (AACAP). The article in this issue by Cervin et al.
    MeSH term(s) Adolescent ; Adolescent Psychiatry ; Child ; Emotions ; Humans ; Obsessive-Compulsive Disorder/diagnosis ; Siblings
    Language English
    Publishing date 2020-01-20
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 392535-3
    ISSN 1527-5418 ; 0890-8567
    ISSN (online) 1527-5418
    ISSN 0890-8567
    DOI 10.1016/j.jaac.2020.01.011
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  3. Article ; Online: Editorial: Outcome Measurement in Pediatric Obsessive-Compulsive Disorder: Current Considerations and Future Directions.

    Scahill, Lawrence / Stewart, S Evelyn

    Journal of the American Academy of Child and Adolescent Psychiatry

    2022  Volume 61, Issue 4, Page(s) 470–472

    Abstract: Our understanding of pediatric obsessive-compulsive disorder (OCD) has come a long way since the important book by Paul Adams. In ;this 1973 book, Obsessive Children: A Sociopsychiatric Study, Adams described 49 youth with OCD, albeit with some blurring ... ...

    Abstract Our understanding of pediatric obsessive-compulsive disorder (OCD) has come a long way since the important book by Paul Adams. In ;this 1973 book, Obsessive Children: A Sociopsychiatric Study, Adams described 49 youth with OCD, albeit with some blurring of OCD and obsessive-compulsive personality disorder. The proposed etiology of OCD rested on psychoanalytic principles and the social psychiatric perspective. This perspective emphasized the importance of social factors in the emergence of mental illness, including OCD. A prevailing view at the time asserted that OCD was a rare, episodic condition often with childhood onset.
    MeSH term(s) Adolescent ; Child ; Compulsive Personality Disorder/psychology ; Humans ; Obsessive-Compulsive Disorder/psychology ; Obsessive-Compulsive Disorder/therapy ; Psychotherapy
    Language English
    Publishing date 2022-01-22
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 392535-3
    ISSN 1527-5418 ; 0890-8567
    ISSN (online) 1527-5418
    ISSN 0890-8567
    DOI 10.1016/j.jaac.2022.01.008
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  4. Article ; Online: Use of Subclinical Phenotypes in Neuroimaging.

    Stewart, S Evelyn

    Journal of the American Academy of Child and Adolescent Psychiatry

    2018  Volume 57, Issue 1, Page(s) 14–15

    MeSH term(s) Brain ; Child ; Humans ; Neuroimaging ; Obsessive-Compulsive Disorder ; Phenotype
    Language English
    Publishing date 2018-01-03
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 392535-3
    ISSN 1527-5418 ; 0890-8567
    ISSN (online) 1527-5418
    ISSN 0890-8567
    DOI 10.1016/j.jaac.2017.11.004
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  5. Article ; Online: Assessing the impact of psychiatric genetic counseling on psychiatric hospitalizations.

    Morris, Emily / McGrail, Kimberlyn / Cressman, Sonya / Stewart, S Evelyn / Austin, Jehannine

    Clinical genetics

    2024  Volume 105, Issue 6, Page(s) 630–638

    Abstract: Psychiatric genetic counseling (pGC) can improve patient empowerment and self-efficacy. We explored the relationship between pGC and psychiatric hospitalizations, for which no prior data exist. Using Population Data BC (a provincial dataset), we tested ... ...

    Abstract Psychiatric genetic counseling (pGC) can improve patient empowerment and self-efficacy. We explored the relationship between pGC and psychiatric hospitalizations, for which no prior data exist. Using Population Data BC (a provincial dataset), we tested two hypotheses: (1) among patients (>18 years) with psychiatric conditions who received pGC between May 2010 and Dec 2016 (N = 387), compared with the year pre-pGC, in the year post-pGC there would be fewer (a) individuals hospitalized and (b) total hospital admissions; and (2) using a matched cohort design, compared with controls (N = 363, matched 1:4 for sex, diagnosis, time since diagnosis, region, and age, and assigned a pseudo pGC index date), the pGC cohort (N = 91) would have (a) more individuals whose number of hospitalizations decreased and (b) fewer hospitalizations post-pGC/pseudo-index. We also explored total days in hospital. Within the pGC cohort, there were fewer hospitalizations post-pGC than pre- pGC (p = 0.011, OR = 1.69), and total days in hospital decreased (1085 to 669). However, when compared to matched controls, the post-pGC/pseudo index change in hospitalizations among pGC cases was not statistically significant, even after controlling for the higher number of hospitalizations prior. pGC may lead to fewer psychiatric hospitalizations and cost savings; further studies exploring this are warranted.
    MeSH term(s) Humans ; Male ; Female ; Hospitalization ; Adult ; Genetic Counseling ; Middle Aged ; Mental Disorders/genetics ; Mental Disorders/epidemiology ; Mental Disorders/therapy ; Cohort Studies ; Young Adult
    Language English
    Publishing date 2024-02-11
    Publishing country Denmark
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 221209-2
    ISSN 1399-0004 ; 0009-9163
    ISSN (online) 1399-0004
    ISSN 0009-9163
    DOI 10.1111/cge.14493
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  6. Article: Retrospective Review of Fluvoxamine-Clomipramine Combination Therapy in Obsessive-Compulsive Disorder in Children and Adolescents.

    Fung, Ryan / Elbe, Dean / Stewart, S Evelyn

    Journal of the Canadian Academy of Child and Adolescent Psychiatry = Journal de l'Academie canadienne de psychiatrie de l'enfant et de l'adolescent

    2021  Volume 30, Issue 3, Page(s) 150–155

    Abstract: Objectives: To inform dosing and describe the pharmacokinetic interaction, efficacy and safety of fluvoxamine-clomipramine combination therapy for treatment-resistant pediatric obsessive-compulsive disorder (OCD).: Methods: A retrospective chart ... ...

    Abstract Objectives: To inform dosing and describe the pharmacokinetic interaction, efficacy and safety of fluvoxamine-clomipramine combination therapy for treatment-resistant pediatric obsessive-compulsive disorder (OCD).
    Methods: A retrospective chart review of OCD-affected patients at a tertiary care children's hospital between January 2010 and August 2017 was conducted. Those included were 18 years of age or younger at initiation of fluvoxamine-clomipramine combination therapy and had at least one set of serum concentration values capturing clomipramine and desmethylclomipramine levels.
    Results: Six adolescents met study inclusion criteria. Fluvoxamine adequately inhibited clomipramine metabolism to desmethylclomipramine in a dose-dependent manner. Fluvoxamine-clomipramine combination therapy was generally well tolerated with no serious or life-threatening adverse effects reported.
    Conclusion: Fluvoxamine-clomipramine combination therapy permits use of lower clomipramine doses than typically used as clomipramine monotherapy and appears to be a safe alternative for pediatric OCD patients failing sequential selective serotonin reuptake inhibitor monotherapy trials. Inter-patient variability and saturable kinetics support therapeutic drug monitoring of serum clomipramine and desmethylclomipramine concentrations to optimize therapy. A proposed algorithm that aligns with current OCD treatment guidelines is described. Further study is needed to evaluate efficacy of this approach.
    Language English
    Publishing date 2021-08-01
    Publishing country Canada
    Document type Journal Article
    ZDB-ID 2381637-5
    ISSN 2293-6122 ; 1719-8429
    ISSN (online) 2293-6122
    ISSN 1719-8429
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  7. Article ; Online: Mindful awareness and resilience skills for adolescents (MARS-A): a mixed-methods study of a mindfulness-based intervention for a heterogeneous adolescent clinical population.

    Vo, Dzung X / Tabi, Katarina / Bhullar, Manreet / Johnson, Andrea / Locke, Jake / Wang, Sophia / Stewart, S Evelyn / Marshall, Sheila K

    International journal of adolescent medicine and health

    2024  Volume 36, Issue 1, Page(s) 25–35

    Abstract: Objectives: Mindful Awareness and Resilience Skills for Adolescents (MARS-A) is a mindfulness-based intervention adapted for the adolescent population. While previous studies have explored the benefits of MARS-A in various single-diagnosis populations, ... ...

    Abstract Objectives: Mindful Awareness and Resilience Skills for Adolescents (MARS-A) is a mindfulness-based intervention adapted for the adolescent population. While previous studies have explored the benefits of MARS-A in various single-diagnosis populations, the aim of this study was to assess MARS-A for a heterogenous clinical adolescent population with mental health and/or chronic diagnoses, focusing on the underlying suffering present in all these conditions rather than its effects on a single diagnosis itself.
    Methods: Qualitative data was collected through interviews to understand post-intervention participant perspectives and experiences. Quantitative data was collected through measures to investigate preliminary secondary outcomes.
    Results: After participating in MARS-A, participants reported qualitative benefits in enhanced well-being, including coping with difficult emotions and managing sleep and/or pain. Quantitative results showed a reduction in functional disability, psychological distress, perceived stress, and depressive symptoms; increase in positive affect; and benefit in coping with pain and chronic conditions.
    Conclusions: MARS-A shows great potential in a heterogeneous clinical adolescent population.
    MeSH term(s) Humans ; Adolescent ; Resilience, Psychological ; Mindfulness/methods ; Emotions ; Coping Skills ; Pain
    Language English
    Publishing date 2024-02-01
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 639287-8
    ISSN 2191-0278 ; 0334-0139
    ISSN (online) 2191-0278
    ISSN 0334-0139
    DOI 10.1515/ijamh-2023-0112
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  8. Article: Response to "

    Fung, Ryan / Elbe, Dean / Stewart, S Evelyn

    Journal of the Canadian Academy of Child and Adolescent Psychiatry = Journal de l'Academie canadienne de psychiatrie de l'enfant et de l'adolescent

    2021  Volume 30, Issue 4, Page(s) 278–279

    Language English
    Publishing date 2021-11-01
    Publishing country Canada
    Document type Journal Article
    ZDB-ID 2381637-5
    ISSN 2293-6122 ; 1719-8429
    ISSN (online) 2293-6122
    ISSN 1719-8429
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  9. Article ; Online: The journey from concealment to disclosure of an obsessive-compulsive disorder diagnosis in the high school setting: A qualitative study exploring youth perspectives.

    Vallani, Tanisha I / Naqqash, Zainab / Lin, Boyee / Lu, Cynthia / Austin, Jehannine C / Stewart, S Evelyn

    Psychiatry research

    2023  Volume 326, Page(s) 115275

    Abstract: Disclosure of an OCD diagnosis in the high school setting could allow for timely provision of individualized school-based supports. As few studies have examined adolescent perspectives on the disclosure process in schools, we adopted a qualitative ... ...

    Abstract Disclosure of an OCD diagnosis in the high school setting could allow for timely provision of individualized school-based supports. As few studies have examined adolescent perspectives on the disclosure process in schools, we adopted a qualitative approach to explore this, and to gather recommendations for making disclosure of OCD at school safer and more helpful. Twelve participants, ranging from 13 to 17 years old, were recruited using maximum variance-based heterogeneous purposive sampling. Semi-structured interviews were conducted and analyzed inductively through Interpretive Description. From participants' stories, we generated a theoretical model describing the journey from concealment of an OCD diagnosis to disclosure. Four phases of youth disclosure were identified: managing enacted and perceived stigma related to the diagnosis, internal bargaining to determine their individualized disclosure boundaries, trust building with school members, and empowerment by being treated as a person first. Participants' recommendations for the school setting included meaningful education, safe spaces, deep reciprocal connections, and confidential personalized support. The model we developed can help inform school disclosure strategies and optimize support to promote best outcomes for youth with OCD.
    MeSH term(s) Humans ; Adolescent ; Disclosure ; Schools ; Social Stigma ; Qualitative Research ; Obsessive-Compulsive Disorder/diagnosis ; Obsessive-Compulsive Disorder/therapy
    Language English
    Publishing date 2023-06-02
    Publishing country Ireland
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 445361-x
    ISSN 1872-7123 ; 1872-7506 ; 0925-4927 ; 0165-1781
    ISSN (online) 1872-7123 ; 1872-7506
    ISSN 0925-4927 ; 0165-1781
    DOI 10.1016/j.psychres.2023.115275
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  10. Article: Commentary: Neurobiology and Therapeutic Potential of Cyclooxygenase-2 (COX-2) Inhibitors for Inflammation in Neuropsychiatric Disorders.

    Westwell-Roper, Clara / Stewart, S Evelyn

    Frontiers in psychiatry

    2020  Volume 11, Page(s) 264

    Language English
    Publishing date 2020-04-22
    Publishing country Switzerland
    Document type Journal Article ; Comment
    ZDB-ID 2564218-2
    ISSN 1664-0640
    ISSN 1664-0640
    DOI 10.3389/fpsyt.2020.00264
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