Article ; Online: Maternal Epigenetic Dysregulation as a Possible Risk Factor for Neurodevelopmental Disorders.
2023 Volume 14, Issue 3
Abstract: Neurodevelopmental Disorders (NDs) are a heterogeneous group of disorders and are considered multifactorial diseases with both genetic and environmental components. Epigenetic dysregulation driven by adverse environmental factors has recently been ... ...
| Abstract | Neurodevelopmental Disorders (NDs) are a heterogeneous group of disorders and are considered multifactorial diseases with both genetic and environmental components. Epigenetic dysregulation driven by adverse environmental factors has recently been documented in neurodevelopmental disorders as the possible etiological agent for their onset. However, most studies have focused on the epigenomes of the probands rather than on a possible epigenetic dysregulation arising in their mothers and influencing neurodevelopment during pregnancy. The aim of this research was to analyze the methylation profile of four well-known genes involved in neurodevelopment ( |
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| MeSH term(s) | Child ; Female ; Pregnancy ; Humans ; Risk Factors ; Neurodevelopmental Disorders/genetics ; Neurodevelopmental Disorders/complications ; Mothers ; Attention Deficit Disorder with Hyperactivity/genetics ; Epigenesis, Genetic |
| Language | English |
| Publishing date | 2023-02-25 |
| Publishing country | Switzerland |
| Document type | Journal Article ; Research Support, Non-U.S. Gov't |
| ZDB-ID | 2527218-4 |
| ISSN | 2073-4425 ; 2073-4425 |
| ISSN (online) | 2073-4425 |
| ISSN | 2073-4425 |
| DOI | 10.3390/genes14030585 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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