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  1. Article ; Online: A stochastic alternative technique for Compton Maximum Likelihood Expectation-Maximization (MLEM) reconstruction.

    Tomazinaki, Mina-Ermioni / Stiliaris, Efstathios

    Computers in biology and medicine

    2023  Volume 166, Page(s) 107502

    Abstract: Even though iterative methods and particularly Maximum Likelihood Expectation-Maximization (MLEM) algorithms have been established in reconstruction with Compton data, their detailed design with respect to physical rules and processes dominate their ... ...

    Abstract Even though iterative methods and particularly Maximum Likelihood Expectation-Maximization (MLEM) algorithms have been established in reconstruction with Compton data, their detailed design with respect to physical rules and processes dominate their plain implementation in the form of a system matrix. A new elementary but efficient alternative for the well-known system matrix with respect to Compton Camera image reconstruction is presented in this work. For each detected event there is a weighting factor inserted as an accumulated probability which carries all the necessary information. This probability which involves only the Compton scattering angle of the incident photon corresponds to a map that correlates all events within all possible source origins. Based on maximizing likelihood principles, the proposed model weights in a stochastic way the difference of the scatterer-to-source angle θ
    Language English
    Publishing date 2023-09-18
    Publishing country United States
    Document type Journal Article
    ZDB-ID 127557-4
    ISSN 1879-0534 ; 0010-4825
    ISSN (online) 1879-0534
    ISSN 0010-4825
    DOI 10.1016/j.compbiomed.2023.107502
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Radiolabeled Iron Oxide Nanoparticles as Dual Modality Contrast Agents in SPECT/MRI and PET/MRI.

    Karageorgou, Maria-Argyro / Bouziotis, Penelope / Stiliaris, Efstathios / Stamopoulos, Dimosthenis

    Nanomaterials (Basel, Switzerland)

    2023  Volume 13, Issue 3

    Abstract: During the last decades, the utilization of imaging modalities such as single photon emission computed tomography (SPECT), positron emission tomography (PET), and magnetic resonance imaging (MRI) in every day clinical practice has enabled clinicians to ... ...

    Abstract During the last decades, the utilization of imaging modalities such as single photon emission computed tomography (SPECT), positron emission tomography (PET), and magnetic resonance imaging (MRI) in every day clinical practice has enabled clinicians to diagnose diseases accurately at early stages. Radiolabeled iron oxide nanoparticles (RIONs) combine their intrinsic magnetic behavior with the extrinsic character of the radionuclide additive, so that they constitute a platform of multifaceted physical properties. Thus, at a practical level, RIONs serve as the physical parent of the so-called dual-modality contrast agents (DMCAs) utilized in SPECT/MRI and PET/MRI applications due to their ability to combine, at real time, the high sensitivity of SPECT or PET together with the high spatial resolution of MRI. This review focuses on the synthesis and in vivo investigation of both biodistribution and imaging efficacy of RIONs as potential SPECT/MRI or PET/MRI DMCAs.
    Language English
    Publishing date 2023-01-27
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2662255-5
    ISSN 2079-4991
    ISSN 2079-4991
    DOI 10.3390/nano13030503
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Gamma-Camera Direct Imaging of the Plasma and On/Intra Cellular Distribution of the

    Karageorgou, Maria-Argyro / Apostolopoulou, Adamantia / Tomazinaki, Mina-Ermioni / Stanković, Dragana / Stiliaris, Efstathios / Bouziotis, Penelope / Stamopoulos, Dimosthenis

    Materials (Basel, Switzerland)

    2024  Volume 17, Issue 2

    Abstract: The radiolabeled iron oxide nanoparticles constitute an attractive choice to be used as dual-modality contrast agents (DMCAs) in nuclear medical diagnosis, due to their ability to combine the benefits of two imaging modalities, for instance single photon ...

    Abstract The radiolabeled iron oxide nanoparticles constitute an attractive choice to be used as dual-modality contrast agents (DMCAs) in nuclear medical diagnosis, due to their ability to combine the benefits of two imaging modalities, for instance single photon emission computed tomography (SPECT) with magnetic resonance imaging (MRI). Before the use of any DMCA, the investigation of its plasma extra- and on/intra cellular distribution in peripheral human blood is of paramount importance. Here, we focus on the in vitro investigation of the distribution of
    Language English
    Publishing date 2024-01-09
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2487261-1
    ISSN 1996-1944
    ISSN 1996-1944
    DOI 10.3390/ma17020335
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: 99m

    Karageorgou, Maria-Argyro / Rapsomanikis, Aristotelis-Nikolaos / Mirković, Marija / Vranješ-Ðurić, Sanja / Stiliaris, Efstathios / Bouziotis, Penelope / Stamopoulos, Dimosthenis

    Nanomaterials (Basel, Switzerland)

    2022  Volume 12, Issue 15

    Abstract: The combination of two imaging modalities in a single agent has received increasing attention during the last few years, since its synergistic action guarantees both accurate and timely diagnosis. For this reason, dual-modality contrast agents (DMCAs), ... ...

    Abstract The combination of two imaging modalities in a single agent has received increasing attention during the last few years, since its synergistic action guarantees both accurate and timely diagnosis. For this reason, dual-modality contrast agents (DMCAs), such as radiolabeled iron oxide (namely Fe
    Language English
    Publishing date 2022-08-08
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662255-5
    ISSN 2079-4991
    ISSN 2079-4991
    DOI 10.3390/nano12152728
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Book ; Online: Attributing Uncertainties in the Identification of Hotspots in SPECT Imaging

    Papanicolas, Costas N. / Koutsantonis, Loizos / Stiliaris, Efstathios

    2020  

    Abstract: In SPECT imaging, the identification and detection of a lesion rely either on visual inspection of the reconstructed tomographic images or post-processing image analysis methods. Both approaches do not provide the capability to attribute a quantifiable ... ...

    Abstract In SPECT imaging, the identification and detection of a lesion rely either on visual inspection of the reconstructed tomographic images or post-processing image analysis methods. Both approaches do not provide the capability to attribute a quantifiable uncertainty to this identification. We present a framework which allows the quantification of this uncertainty and the assignment of a level of confidence to the detection of hotspots. Based on the "Reconstructed Image from Simulations Ensemble" (RISE), an image reconstruction method, the presented scheme uses the set of projection measurements to derive the parameters defining the uptake of radioactivity, the position and the size of a hotspot, and as well as their associated uncertainties. The capabilities of the proposed method are demonstrated with projection data from GATE phantom simulations.

    Comment: 6 pages, 6 figures, Presentation in IEEE NSS/MIC 2018 Conference
    Keywords Electrical Engineering and Systems Science - Image and Video Processing ; Physics - Data Analysis ; Statistics and Probability ; Physics - Medical Physics
    Subject code 620
    Publishing date 2020-08-26
    Publishing country us
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Book ; Thesis: Refraktion und Kernregenbogenstreuung schwerer Ionen

    Stiliaris, Efstathios

    1988  

    Author's details von Efstathios Stiliaris
    Language German
    Size 99, A7 S, graph. Darst
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Freie Univ., Diss.--Berlin, 1989
    Database Former special subject collection: coastal and deep sea fishing

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  7. Book: Refraktion und Kernregenbogenstreuung schwerer Ionen

    Stiliaris, Efstathios

    1988  

    Author's details Efstathios Stiliaris
    Size II, 90, 7 S, graph. Darst, 21 cm
    Document type Book
    Note Berlin, Freie Univ., Diss., 1989
    Database Library catalogue of the German National Library of Science and Technology (TIB), Hannover

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  8. Article: Polymer gel dosimetry close to an 125I interstitial brachytherapy seed.

    Pantelis, E / Lymperopoulou, G / Papagiannis, P / Sakelliou, L / Stiliaris, E / Sandilos, P / Seimenis, I / Kozicki, M / Rosiak, J M

    Physics in medicine and biology

    2005  Volume 50, Issue 18, Page(s) 4371–4384

    Abstract: Despite its advantages, the polymer gel-magnetic resonance imaging (MRI) method has not, as yet, been successfully employed in dosimetry of low energy/low dose rate photon-emitting brachytherapy sources such as 125I or 103Pd interstitial seeds. In the ... ...

    Abstract Despite its advantages, the polymer gel-magnetic resonance imaging (MRI) method has not, as yet, been successfully employed in dosimetry of low energy/low dose rate photon-emitting brachytherapy sources such as 125I or 103Pd interstitial seeds. In the present work, two commercially available 125I seed sources, each of approximately 0.5 U, were positioned at two different locations of a polymer gel filled vial. The gel vial was MR scanned with the sources in place 19 and 36 days after seed implantation. Calibration curves were acquired from the coupling of MRI measurements with accurate Monte Carlo dose calculations obtained simulating the exact experimental setup geometry and materials. The obtained gel response data imply that while linearity of response is sustained, sensitivity (calibration curve slope) is significantly increased (approximately 60%) compared to its typical value for the 192Ir (or 60Co and 6 MV LINAC) photon energies. Water equivalence and relative energy response corrections of the gel cannot account for more than 3-4% of this increase, which, therefore, has to be mainly attributed to physicochemical processes related to the low dose rate of the sources and the associated prolonged irradiation time. The calibration data obtained from one 125I source were used to provide absolute dosimetry results for the other 125I source, which were found to agree with corresponding Monte Carlo calculations within experimental uncertainties. It is therefore suggested that, regardless of the underlying factors accounting for the gel dose response to 125I irradiations, polymer gel dosimetry of new 125I or 103Pd sources should be carried out as originally proposed by Heard and Ibbot (2004 J. Phys.: Conf. Ser. 3 221-3), i.e., by irradiating the same gel sample with the new low dose rate source, as well as with a well-characterized low dose rate source which will provide the dose calibration curve for the same irradiation conditions.
    MeSH term(s) Brachytherapy/instrumentation ; Brachytherapy/methods ; Calibration ; Gels ; Iodine Radioisotopes/therapeutic use ; Magnetic Resonance Imaging ; Monte Carlo Method ; Photons ; Polymers/chemistry ; Radiation Dosage ; Radiometry/methods ; Radiotherapy Planning, Computer-Assisted/methods
    Chemical Substances Gels ; Iodine Radioisotopes ; Polymers
    Language English
    Publishing date 2005-09-21
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 208857-5
    ISSN 1361-6560 ; 0031-9155
    ISSN (online) 1361-6560
    ISSN 0031-9155
    DOI 10.1088/0031-9155/50/18/009
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Transfer vs. Breakup in the interaction of the 7Be Radioactive Ion Beam with a 58Ni target at Coulomb barrier energies

    Mazzocco M. / Torresi D. / Acosta L. / Boiano A. / Boiano C. / Fierro N. / Glodariu T. / Guglielmetti A. / Keeley N. / La Commara M. / Martel I. / Mazzocchi C. / Molini P. / Pakou A. / Parascandolo C. / Parkar V.V. / Patronis N. / Pierroutsakou D. / Romoli M. /
    Rusek K. / Sanchez-Benitez A.M. / Sandoli M. / Signorini C. / Silvestri R. / Soramel F. / Stiliaris E. / Strano E. / Stroe L. / Zerva K.

    EPJ Web of Conferences, Vol 66, p

    2014  Volume 03060

    Abstract: We measured for the first time 7Be elastically scattered nuclei as well as 3,4He reaction products from a 58Ni target at 22.3 MeV beam energy. The data were analyzed within the optical model formalism to extract the total reaction cross section. ... ...

    Abstract We measured for the first time 7Be elastically scattered nuclei as well as 3,4He reaction products from a 58Ni target at 22.3 MeV beam energy. The data were analyzed within the optical model formalism to extract the total reaction cross section. Extensive kinematical, Distorted Wave Born Approximation (DWBA)and Continuum Discretized Coupled Channel (CDCC) calculations were performed to investigate the 3,4He originating mechanisms and the interplay between different reaction channels.
    Keywords Physics ; QC1-999 ; Science ; Q
    Language English
    Publishing date 2014-03-01T00:00:00Z
    Publisher EDP Sciences
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  10. Article: Cold multiproton-transfer reactions in the system 86Kr+54Fe below the Coulomb barrier.

    Wilpert / Gebauer / von Oertzen W / Stiliaris / Bohlen

    Physical review. C, Nuclear physics

    1991  Volume 44, Issue 3, Page(s) 1081–1085

    Language English
    Publishing date 1991-09
    Publishing country United States
    Document type Journal Article
    ZDB-ID 209771-0
    ISSN 1089-490X ; 0556-2813 ; 2469-9985
    ISSN (online) 1089-490X
    ISSN 0556-2813 ; 2469-9985
    DOI 10.1103/physrevc.44.1081
    Database MEDical Literature Analysis and Retrieval System OnLINE

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