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  1. Article: Analysis of the First 300 Cases of SARS CoV2 Infection from the Infection Disease Clinic of Craiova, Romania.

    Giubelan, Lucian-Ion / Dumitrescu, Florentina / Stoian, Andreea Cristina / Dragonu, Livia

    Current health sciences journal

    2021  Volume 47, Issue 1, Page(s) 28–32

    Abstract: COVID-19 is an ongoing pandemic and an intermediate analysis of the first 300 cases treated in the Infectious Diseases Clinic from Craiova has been performed. We have found that most of the cases were asymptomatic or mild, but the severity of the ... ...

    Abstract COVID-19 is an ongoing pandemic and an intermediate analysis of the first 300 cases treated in the Infectious Diseases Clinic from Craiova has been performed. We have found that most of the cases were asymptomatic or mild, but the severity of the symptomatic cases increases with age. The main comorbidities associated mainly with the severe cases were high blood pressure, obesity, other cardiac conditions, diabetes mellitus and malignancies. Inflammation, coagulation and metabolic disorders are significantly more expressed in critically ill patients. Fatality rate is relatively low, death seems to be associated with old age.
    Language English
    Publishing date 2021-03-31
    Publishing country Romania
    Document type Journal Article
    ZDB-ID 2708703-7
    ISSN 2069-4032 ; 2067-0656
    ISSN (online) 2069-4032
    ISSN 2067-0656
    DOI 10.12865/CHSJ.47.01.05
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Aspects of Humoral Immunity after Vaccination with Bnt162b2: A Small Study.

    Giubelan, Lucian-Ion / Dumitrescu, Florentina / Dragonu, Livia / Stoian, Andreea Cristina / Ilie, Cristina / Stanciu, Ilona

    Current health sciences journal

    2022  Volume 48, Issue 1, Page(s) 24–28

    Abstract: Starting from December 2020, vaccination against COVID-19 became available in Romania. There are a lot of uncertainties regarding the kinetics of immunity and its persistance over time. This is a small prospective study developed between January- ... ...

    Abstract Starting from December 2020, vaccination against COVID-19 became available in Romania. There are a lot of uncertainties regarding the kinetics of immunity and its persistance over time. This is a small prospective study developed between January-September 2021 in the Infectious Diseases Clinic from Craiova and comprising 61 subjects immunised with BNT162b2 (Comirnaty). We have found that after two doses of vaccine there is a strong humoral response, but the immunity lowers six months later. Subjects with a diagnosis of COVID-19, previously or in between the two doses, have had the most significant immunological response, but, also, the sharpest decline in antibody titer. The immune response seems to be the same, regardless the gender of the subjects. There are a variety of responses at the individual level, but overall vaccine effectiveness is 96.72% two weeks following immunisation and 88.52% after six months; however for those who have been in contact with the virus, they all had an antibody titer well above the laboratory limit.
    Language English
    Publishing date 2022-03-31
    Publishing country Romania
    Document type Journal Article
    ZDB-ID 2708703-7
    ISSN 2069-4032 ; 2067-0656
    ISSN (online) 2069-4032
    ISSN 2067-0656
    DOI 10.12865/CHSJ.48.01.03
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Seroprevalence of Infections with TORCH Agents in Romania: A Systematic Review.

    Radoi, Cristiana Luiza / Zlatian, Ovidiu / Balasoiu, Maria / Giubelan, Lucian / Stoian, Andreea Cristina / Dragonu, Livia / Neacsu, Alexandru / Iliescu, Dominic Gabriel

    Microorganisms

    2023  Volume 11, Issue 8

    Abstract: Maternal-fetal infectious pathology-notably the TORCH panel ( ...

    Abstract Maternal-fetal infectious pathology-notably the TORCH panel (
    Language English
    Publishing date 2023-08-20
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2720891-6
    ISSN 2076-2607
    ISSN 2076-2607
    DOI 10.3390/microorganisms11082120
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Toxoplasma gondii

    Radoi, Cristiana Luiza / Zlatian, Ovidiu Mircea / Balasoiu, Maria / Giubelan, Lucian / Stoian, Andreea Cristina / Dragonu, Livia / Neacsu, Alexandru / Iliescu, Dominic Gabriel

    Microorganisms

    2023  Volume 11, Issue 8

    Abstract: Toxoplasmosis, caused by the obligate intracellular protozoan parasite Toxoplasma gondii ( ...

    Abstract Toxoplasmosis, caused by the obligate intracellular protozoan parasite Toxoplasma gondii (
    Language English
    Publishing date 2023-08-10
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2720891-6
    ISSN 2076-2607
    ISSN 2076-2607
    DOI 10.3390/microorganisms11082057
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: In-stent restenosis in acute coronary syndrome-a classic and a machine learning approach.

    Scafa-Udriște, Alexandru / Itu, Lucian / Puiu, Andrei / Stoian, Andreea / Moldovan, Horatiu / Popa-Fotea, Nicoleta-Monica

    Frontiers in cardiovascular medicine

    2023  Volume 10, Page(s) 1270986

    Abstract: Background: In acute coronary syndrome (ACS), a number of previous studies tried to identify the risk factors that are most likely to influence the rate of in-stent restenosis (ISR), but the contribution of these factors to ISR is not clearly defined. ... ...

    Abstract Background: In acute coronary syndrome (ACS), a number of previous studies tried to identify the risk factors that are most likely to influence the rate of in-stent restenosis (ISR), but the contribution of these factors to ISR is not clearly defined. Thus, the need for a better way of identifying the independent predictors of ISR, which comes in the form of Machine Learning (ML).
    Objectives: The aim of this study is to evaluate the relationship between ISR and risk factors associated with ACS and to develop and validate a nomogram to predict the probability of ISR through the use of ML in patients undergoing percutaneous coronary intervention (PCI).
    Methods: Consecutive patients presenting with ACS who were successfully treated with PCI and who had an angiographic follow-up after at least 3 months were included in the study. ISR risk factors considered into the study were demographic, clinical and peri-procedural angiographic lesion risk factors. We explored four ML techniques (Random Forest (RF), support vector machines (SVM), simple linear logistic regression (LLR) and deep neural network (DNN)) to predict the risk of ISR. Overall, 21 features were selected as input variables for the ML algorithms, including continuous, categorical and binary variables.
    Results: The total cohort of subjects included 340 subjects, in which the incidence of ISR observed was 17.68% (
    Conclusion: ML models applied in patients after PCI can contribute to a better differentiation of the future risk of ISR.
    Language English
    Publishing date 2023-12-22
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2781496-8
    ISSN 2297-055X
    ISSN 2297-055X
    DOI 10.3389/fcvm.2023.1270986
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: The Role of QuantiFERON-TB Gold Plus in Mycobacterium Tuberculosis Detection in a Severe HIV Immunocompromised Patient—Case Report

    Dumitrescu, Florentina / Pisoschi, Cătălina-Gabriela / Pădureanu, Vlad / Stoian, Andreea Cristina / Dragonu, Livia / Giubelan, Lucian

    Pathogens. 2021 Nov. 21, v. 10, no. 11

    2021  

    Abstract: Tuberculosis (TB) is an important opportunistic infection in HIV-positive people. We are reporting a case of a 31-year-old HIV-infected patient who was hospitalized in July 2021 for dyspnea, cough with mucopurulent sputum and asthenia. He was confirmed ... ...

    Abstract Tuberculosis (TB) is an important opportunistic infection in HIV-positive people. We are reporting a case of a 31-year-old HIV-infected patient who was hospitalized in July 2021 for dyspnea, cough with mucopurulent sputum and asthenia. He was confirmed to have Serratia liquefaciens pneumonia and acute respiratory failure. The evolution was unfavorable despite the antibiotic, pathogenic and symptomatic treatment. Because the patient had severe immunosuppression (CD4 count = 37 cell/mm³), we used QuantiFERON-TB Gold Plus for the detection of the Mycobacterium tuberculosis infection. The antituberculosis therapy was initiated, which resulted in a significant improvement of the general condition and the patient was discharged with the recommendation to continue antiretroviral therapy, antituberculosis treatment and Trimethoprim/Sulfamethoxazole—single tablet daily for the prophylaxis of Pneumocystis pneumonia.
    Keywords HIV infections ; Mycobacterium tuberculosis ; Pneumocystis ; antibiotics ; antiretroviral agents ; cough ; disease prevention ; dyspnea ; evolution ; immunosuppression ; opportunistic infection ; patients ; pneumonia ; therapeutics ; tuberculosis
    Language English
    Dates of publication 2021-1121
    Publishing place Multidisciplinary Digital Publishing Institute
    Document type Article
    ZDB-ID 2695572-6
    ISSN 2076-0817
    ISSN 2076-0817
    DOI 10.3390/pathogens10111523
    Database NAL-Catalogue (AGRICOLA)

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  7. Article: The Role of QuantiFERON-TB Gold Plus in Mycobacterium Tuberculosis Detection in a Severe HIV Immunocompromised Patient-Case Report.

    Dumitrescu, Florentina / Pisoschi, Cătălina-Gabriela / Pădureanu, Vlad / Stoian, Andreea Cristina / Dragonu, Livia / Giubelan, Lucian

    Pathogens (Basel, Switzerland)

    2021  Volume 10, Issue 11

    Abstract: Tuberculosis (TB) is an important opportunistic infection in HIV-positive people. We are reporting a case of a 31-year-old HIV-infected patient who was hospitalized in July 2021 for dyspnea, cough with mucopurulent sputum and asthenia. He was confirmed ... ...

    Abstract Tuberculosis (TB) is an important opportunistic infection in HIV-positive people. We are reporting a case of a 31-year-old HIV-infected patient who was hospitalized in July 2021 for dyspnea, cough with mucopurulent sputum and asthenia. He was confirmed to have Serratia liquefaciens pneumonia and acute respiratory failure. The evolution was unfavorable despite the antibiotic, pathogenic and symptomatic treatment. Because the patient had severe immunosuppression (CD4 count = 37 cell/mm
    Language English
    Publishing date 2021-11-21
    Publishing country Switzerland
    Document type Case Reports
    ZDB-ID 2695572-6
    ISSN 2076-0817
    ISSN 2076-0817
    DOI 10.3390/pathogens10111523
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: How vulnerable is fiscal policy in Central and Eastern European countries?

    Stoian, Andreea

    Romanian journal of fiscal policy : RJFP Vol. 3, No. 2 , p. 68-81

    2012  Volume 3, Issue 2, Page(s) 68–81

    Abstract: The aim of this paper is to investigate the vulnerability of fiscal policy in the case of 10 Central and Eastern European countries. We use a newly introduce indicator named Cumulative Excess of the Primary Balance (CEPB) which shows the deviations of ... ...

    Author's details Andreea Stoian
    Abstract The aim of this paper is to investigate the vulnerability of fiscal policy in the case of 10 Central and Eastern European countries. We use a newly introduce indicator named Cumulative Excess of the Primary Balance (CEPB) which shows the deviations of current fiscal policy from a fiscal rule implying the stabilization of the public debt. Using annual data extracted for 1996-2010 period, we find no evidence of fiscal vulnerability in the case of Bulgaria and Estonia. For rest of the countries the results indicate more or less fiscal vulnerability depending how large CEPB is.
    Keywords Fiscal policy ; Primary balance ; Public debt ; Fiscal sustainability
    Language English
    Size Online-Ressource, graph. Darst.
    Publisher Editura ASE
    Publishing place București
    Document type Article ; Online
    Note IMD-Felder maschinell generiert
    ZDB-ID 2660586-7
    ISSN 2069-0983
    ISSN 2069-0983
    Database ECONomics Information System

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  9. Article: Human Anthrax in Dolj County, Romania-A Series of Three Cases.

    Dumitrescu, Florentina / Georgescu, Eugen Florin / Giubelan, Lucian / Pădureanu, Vlad / Stoian, Andreea Cristina / Dincă, Viorica / Georgescu, Milena / Dragonu, Livia / Marinescu, Daniela

    Pathogens (Basel, Switzerland)

    2021  Volume 10, Issue 6

    Abstract: ... Bacillus ... ...

    Abstract Bacillus anthracis
    Language English
    Publishing date 2021-05-23
    Publishing country Switzerland
    Document type Case Reports
    ZDB-ID 2695572-6
    ISSN 2076-0817
    ISSN 2076-0817
    DOI 10.3390/pathogens10060644
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Lemierre's Syndrome: Case Presentation of a Rare and Possibly Life-Threatening Condition.

    Giubelan, Lucian / Dragonu, Livia / Pădureanu, Vlad / Neacșu, Alexandru / Mănescu, Mirela / Stoian, Andreea Cristina / Dumitrescu, Florentina

    Medicina (Kaunas, Lithuania)

    2021  Volume 57, Issue 10

    Abstract: Lemierre's syndrome is, presently, a very rare condition, but a life-threatening one. The syndrome was first described in 1936 by Andre Lemierre and comprises an oropharyngeal infection (most commonly associated with anaerobic ... ...

    Abstract Lemierre's syndrome is, presently, a very rare condition, but a life-threatening one. The syndrome was first described in 1936 by Andre Lemierre and comprises an oropharyngeal infection (most commonly associated with anaerobic bacteria
    MeSH term(s) Fusobacterium necrophorum ; Humans ; Jugular Veins/diagnostic imaging ; Lemierre Syndrome/diagnosis ; Lemierre Syndrome/drug therapy ; Sepsis ; Thrombophlebitis/diagnosis ; Thrombophlebitis/drug therapy
    Language English
    Publishing date 2021-10-14
    Publishing country Switzerland
    Document type Case Reports
    ZDB-ID 2188113-3
    ISSN 1648-9144 ; 1010-660X
    ISSN (online) 1648-9144
    ISSN 1010-660X
    DOI 10.3390/medicina57101102
    Database MEDical Literature Analysis and Retrieval System OnLINE

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