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  1. Article ; Online: Cancer stem cells: current status and future directions.

    Stoica, George

    Veterinary journal (London, England : 1997)

    2015  Volume 205, Issue 2, Page(s) 124–125

    MeSH term(s) Animals ; Neoplastic Stem Cells ; Stem Cells
    Language English
    Publishing date 2015-08
    Publishing country England
    Document type Comment ; Editorial
    ZDB-ID 428614-5
    ISSN 1532-2971 ; 0372-5545 ; 1090-0233
    ISSN (online) 1532-2971
    ISSN 0372-5545 ; 1090-0233
    DOI 10.1016/j.tvjl.2015.02.002
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.B 552: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  2. Book ; Online: ZipIt! Merging Models from Different Tasks without Training

    Stoica, George / Bolya, Daniel / Bjorner, Jakob / Hearn, Taylor / Hoffman, Judy

    2023  

    Abstract: Typical deep visual recognition models are capable of performing the one task they were trained on. In this paper, we tackle the extremely difficult problem of combining completely distinct models with different initializations, each solving a separate ... ...

    Abstract Typical deep visual recognition models are capable of performing the one task they were trained on. In this paper, we tackle the extremely difficult problem of combining completely distinct models with different initializations, each solving a separate task, into one multi-task model without any additional training. Prior work in model merging permutes one model to the space of the other then adds them together. While this works for models trained on the same task, we find that this fails to account for the differences in models trained on disjoint tasks. Thus, we introduce "ZipIt!", a general method for merging two arbitrary models of the same architecture that incorporates two simple strategies. First, in order to account for features that aren't shared between models, we expand the model merging problem to additionally allow for merging features within each model by defining a general "zip" operation. Second, we add support for partially zipping the models up until a specified layer, naturally creating a multi-head model. We find that these two changes combined account for a staggering 20-60% improvement over prior work, making the merging of models trained on disjoint tasks feasible.
    Keywords Computer Science - Computer Vision and Pattern Recognition ; Computer Science - Machine Learning
    Subject code 004
    Publishing date 2023-05-04
    Publishing country us
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Book ; Online: Dynamic Batch Adaptation

    Simionescu, Cristian / Stoica, George / Herscovici, Robert

    2022  

    Abstract: Current deep learning adaptive optimizer methods adjust the step magnitude of parameter updates by altering the effective learning rate used by each parameter. Motivated by the known inverse relation between batch size and learning rate on update step ... ...

    Abstract Current deep learning adaptive optimizer methods adjust the step magnitude of parameter updates by altering the effective learning rate used by each parameter. Motivated by the known inverse relation between batch size and learning rate on update step magnitudes, we introduce a novel training procedure that dynamically decides the dimension and the composition of the current update step. Our procedure, Dynamic Batch Adaptation (DBA) analyzes the gradients of every sample and selects the subset that best improves certain metrics such as gradient variance for each layer of the network. We present results showing DBA significantly improves the speed of model convergence. Additionally, we find that DBA produces an increased improvement over standard optimizers when used in data scarce conditions where, in addition to convergence speed, it also significantly improves model generalization, managing to train a network with a single fully connected hidden layer using only 1% of the MNIST dataset to reach 97.79% test accuracy. In an even more extreme scenario, it manages to reach 97.44% test accuracy using only 10 samples per class. These results represent a relative error rate reduction of 81.78% and 88.07% respectively, compared to the standard optimizers, Stochastic Gradient Descent (SGD) and Adam.
    Keywords Computer Science - Machine Learning ; Computer Science - Artificial Intelligence ; Computer Science - Computer Vision and Pattern Recognition
    Subject code 006
    Publishing date 2022-08-01
    Publishing country us
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Article: PRELIMINARY STUDY ON SKIN CANCER DETECTION IN SENCAR MICE USING MUELLER OPTICAL COHERENCE TOMOGRAPHY.

    Todorović, Miloš / Jiao, Shuliang / Stoica, George / Wang, Lihong V

    Journal of innovative optical health sciences

    2021  Volume 2, Issue 3, Page(s) 289–294

    Abstract: We report on the use of a fiber-based Mueller-matrix optical coherence tomography (OCT) system with continuous source-polarization modulation ... ...

    Abstract We report on the use of a fiber-based Mueller-matrix optical coherence tomography (OCT) system with continuous source-polarization modulation for
    Language English
    Publishing date 2021-04-26
    Publishing country Singapore
    Document type Journal Article
    ZDB-ID 2515441-2
    ISSN 1793-7205 ; 1793-5458
    ISSN (online) 1793-7205
    ISSN 1793-5458
    DOI 10.1142/s1793545809000577
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Custom-Made Direct Metal Laser Sintering Titanium Subperiosteal Implants in Oral and Maxillofacial Surgery for Severe Bone-Deficient Patients-A Pilot Study.

    Nemtoi, Alexandru / Covrig, Vlad / Nemtoi, Ana / Stoica, George / Vatavu, Ruxandra / Haba, Danisia / Zetu, Irina

    Diagnostics (Basel, Switzerland)

    2022  Volume 12, Issue 10

    Abstract: Background: Nowadays, a combination of classical subperiosteal implant designs with 3D imaging and printing allows one to reduce treatment time and provides support for fixed prostheses in cases where other techniques do not provide satisfactory results. ...

    Abstract Background: Nowadays, a combination of classical subperiosteal implant designs with 3D imaging and printing allows one to reduce treatment time and provides support for fixed prostheses in cases where other techniques do not provide satisfactory results. This study aims to present a digital technique for the manufacturing of custom-made subperiosteal implants and what complications might appear after this type of surgery.
    Methods: Sixteen patients treated with a custom-made DMLS titanium subperiosteal implant during the period between October 2021 and February 2022 were enrolled in the study. Orthopantomography (OPT) and cone-beam computer tomography (CBCT) were recorded for all patients. The measurements taken into account in this study were the fit and stability of implants, duration of surgery, implant survival, and early and late complications.
    Results: The fit of the implants was extremely satisfactory, with a mean rating of 4 out of 5. The mean duration of the intervention was 86.18 min. At the end of the study, one implant was lost due to insufficient fit and recurrent, untreatable infections. Eleven implants (69%) were placed on the maxillary and five (31%) implants were placed on the mandible.
    Conclusions: Taking this into consideration, custom-made DMLS titanium subperiosteal implants could present satisfactory implant survival and low complication rates.
    Language English
    Publishing date 2022-10-19
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662336-5
    ISSN 2075-4418
    ISSN 2075-4418
    DOI 10.3390/diagnostics12102531
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Mechanisms of Altered Immune Response in Skin Melanoma.

    Fruntealată, Radu-Florin / Marius, Matei / Boboc, Ianis Kevyn Stefan / Mitran, Smaranda Ioana / Ciurea, Marius Eugen / Stoica, George-Alin

    Current health sciences journal

    2023  Volume 49, Issue 3, Page(s) 297–311

    Abstract: Melanoma, a deadly form of skin cancer, poses significant challenges to the host immune system, allowing tumor cells to evade immune surveillance and persist. This complex interplay between melanoma and the immune system involves a multitude of ... ...

    Abstract Melanoma, a deadly form of skin cancer, poses significant challenges to the host immune system, allowing tumor cells to evade immune surveillance and persist. This complex interplay between melanoma and the immune system involves a multitude of mechanisms that impair immune recognition and promote tumor progression. This review summarizes the intricate strategies employed by melanoma cells to evade the immune response, including defective immune recognition, immune checkpoint activation, and the role of regulatory T-cells, myeloid-derived suppressor cells, and exosomes in suppressing anti-tumor immunity. Additionally, we discuss potential therapeutic targets aimed at reversing immune evasion in melanoma, highlighting the importance of understanding these mechanisms for developing more effective immunotherapies. Improved insights into the interactions between melanoma and the immune system will aid in the development of novel treatment strategies to enhance anti-tumor immune responses and improve patient outcomes.
    Language English
    Publishing date 2023-09-30
    Publishing country Romania
    Document type Journal Article ; Review
    ZDB-ID 2708703-7
    ISSN 2069-4032 ; 2067-0656
    ISSN (online) 2069-4032
    ISSN 2067-0656
    DOI 10.12865/CHSJ.49.03.01
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Retrospective Study Over the Hypospadias Surgery in a Single Tertiary Center.

    Fruntelată, Radu / Stoica, George Alin / Ciobanu, Mircea Ovidiu / Ciurea, Marius Eugen / Nica, Oliviu / Stoica, Maria

    Current health sciences journal

    2021  Volume 47, Issue 2, Page(s) 177–183

    Abstract: Hypospadias surgery is a common activity in every department for pediatric surgery, increased incidence of this condition contributing this aspect. For this purpose permanent review of the data of cases is probably necessary, in order to promptly ... ...

    Abstract Hypospadias surgery is a common activity in every department for pediatric surgery, increased incidence of this condition contributing this aspect. For this purpose permanent review of the data of cases is probably necessary, in order to promptly evaluate short and long term results.
    Material and methods: The authors are presenting this retrospective clinical and statistical study, enrolling 149 patients, hospitalized and operated in the Department of Pediatric Surgery and Orthopedics, between 2009 and 2018. several parameters were taken into consideration: moment of conception, type of hypospadias, associated malformations, use of meatoplasty, age at meatoplasty, age at urethroplasty, type of urethroplasty, postoperative incidents and complications.
    Results: Most of the patients included in the study were classified as anterior type of hypospadias, associated malformations were present in 20,13% of the patients, and 80% of the associated malformations belonged to the urogenital system. Over 60% of the cases underwent meatoplasty as a tactical procedure. Mathieu was the most appreciated procedure (74,5%) for urethroplasty and over a half of the patients were operated after the age of 3 years. Early and late postoperative fistula formation was noted in 18,12% of cases.
    Conclusions: Better parameters to assess the exact type of hypospadias are needed to be introduced. Also, clear protocols for preoperative work-up in detection of other abnormalities, especially genito-urinary. Meatoplasty as a tactical procedure is having unclear influence for urethroplasty. Decreasing the age at urethroplasty should be the next goal. Some surgeons should really get overspecialized for this type of surgery.
    Language English
    Publishing date 2021-06-30
    Publishing country Romania
    Document type Journal Article
    ZDB-ID 2708703-7
    ISSN 2069-4032 ; 2067-0656
    ISSN (online) 2069-4032
    ISSN 2067-0656
    DOI 10.12865/CHSJ.47.02.05
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Book ; Online: Improving Relation Extraction by Leveraging Knowledge Graph Link Prediction

    Stoica, George / Platanios, Emmanouil Antonios / Póczos, Barnabás

    2020  

    Abstract: Relation extraction (RE) aims to predict a relation between a subject and an object in a sentence, while knowledge graph link prediction (KGLP) aims to predict a set of objects, O, given a subject and a relation from a knowledge graph. These two problems ...

    Abstract Relation extraction (RE) aims to predict a relation between a subject and an object in a sentence, while knowledge graph link prediction (KGLP) aims to predict a set of objects, O, given a subject and a relation from a knowledge graph. These two problems are closely related as their respective objectives are intertwined: given a sentence containing a subject and an object o, a RE model predicts a relation that can then be used by a KGLP model together with the subject, to predict a set of objects O. Thus, we expect object o to be in set O. In this paper, we leverage this insight by proposing a multi-task learning approach that improves the performance of RE models by jointly training on RE and KGLP tasks. We illustrate the generality of our approach by applying it on several existing RE models and empirically demonstrate how it helps them achieve consistent performance gains.
    Keywords Computer Science - Computation and Language
    Publishing date 2020-12-08
    Publishing country us
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  9. Article: The Impact of Competitive Sports on Oral Health: Exploring Their Relationship with Salivary Oxidative Stress in Children.

    Matei, Mădălina Nicoleta / Popa, Paul Șerban / Covaci, Antonela Magdalena / Chipirliu, Oana / Earar, Kamel / Stoica, George / Zaharia, Andreea Eliza / Maftei, Nicoleta Maricica / Gurău, Gabriela / Lisă, Elena Lăcrămioara / Zaharescu, Anamaria

    Healthcare (Basel, Switzerland)

    2023  Volume 11, Issue 22

    Abstract: This article explores the correlation between salivary biomarkers, such as glutathione peroxidase (GPX), total antioxidant capacity (TAC), and superoxide dismutase (SOD), and their association with oral health for children in competitive sports. Saliva ... ...

    Abstract This article explores the correlation between salivary biomarkers, such as glutathione peroxidase (GPX), total antioxidant capacity (TAC), and superoxide dismutase (SOD), and their association with oral health for children in competitive sports. Saliva has emerged as a valuable resource for evaluating physiological and pathological conditions due to its non-invasive collection method and easy storage. This study examines the potential of GPX, TAC, and SOD as salivary biomarkers for assessing the impact of competitive sports on children's oral health. It discusses the potential implications of increased oxidative stress due to intense physical activity and the role of antioxidant defense mechanisms in maintaining oral health. In total, 173 children aged between 6 and 17 were divided into three groups, 58 hockey players, 55 football players, and 60 in the control group, and examined to assess their oral hygiene and dental and periodontal health. Saliva was collected, centrifuged, and the supernatant was analyzed for the relevant biomarkers. The findings seem to suggest that salivary biomarkers, like GPX, TAC, and SOD, might serve as indicators of the physiological response to competitive sports in children, as well as indicators of oral health, especially dental cavities, and periodontal disease. Statistical analysis showed significant differences between the groups, with better values for athletes, regardless of age, sex, or activity type. Understanding the relationship between salivary biomarkers and competitive sports in children can have significant implications for monitoring and optimizing the health and performance of young athletes. Further research is needed to establish the specific associations between these biomarkers and the effects of several types and intensities of sports activities on oral health in children.
    Language English
    Publishing date 2023-11-08
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2721009-1
    ISSN 2227-9032
    ISSN 2227-9032
    DOI 10.3390/healthcare11222927
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Retrospective Study of a Patient with Multiple de Novo Skin Tumor Formations.

    Fruntealată, Radu-Florin / Balseanu, Tudor Adrian / Nica, Oliviu / Negrila, Alina Andreea / Petrovici, Ilaria Lorena / Marinescu, Elena Alexandra / Stoica, George-Alin / Stoica, Maria / Ciurea, Ana-Maria / Ciurea, Marius-Eugen

    Current health sciences journal

    2023  Volume 49, Issue 3, Page(s) 434–437

    Abstract: In Romania, the incidence of malignant melanocytic tumors is continuously increasing. According to the World Health Organization, the incidence of melanocytic and non-melanocytic skin neoplasms has increased considerably and globally, in the last decade. ...

    Abstract In Romania, the incidence of malignant melanocytic tumors is continuously increasing. According to the World Health Organization, the incidence of melanocytic and non-melanocytic skin neoplasms has increased considerably and globally, in the last decade. We present the case of a 49-year-old patient who, over the course of 7 years, came in the Plastic Surgery Clinic of the Emergency County Hospital of Craiova for the excision of a number of 25 skin tumor formations, located on the face, cervical region, trunk and upper limbs. Treatment included complete microsurgical excision and supervision. In the end, the patient's treatment compliance decreased significantly.
    Language English
    Publishing date 2023-09-30
    Publishing country Romania
    Document type Case Reports
    ZDB-ID 2708703-7
    ISSN 2069-4032 ; 2067-0656
    ISSN (online) 2069-4032
    ISSN 2067-0656
    DOI 10.12865/CHSJ.49.03.18
    Database MEDical Literature Analysis and Retrieval System OnLINE

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