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Article ; Online: Cardio-cerebral infarction

Stojanović Jelena

Halo 194, Vol 27, Iss 1, Pp 19-

2021 Volume 23

Abstract: Introduction/Objective Acute myocardial infarction (AMI) and acute ischemic cerebral infarction (AICI) are both leading causes of death around the world. A simultaneous occurrence of these conditions is called a cardio-cerebral infarction (CCI). We are ... ...

Abstract	Introduction/Objective Acute myocardial infarction (AMI) and acute ischemic cerebral infarction (AICI) are both leading causes of death around the world. A simultaneous occurrence of these conditions is called a cardio-cerebral infarction (CCI). We are presenting a case of CCI detected in the prehospital setting as a rarity. Case report: The patient presented is a 78-year-old woman with simultaneous development of AMI and AICI. The diagnosis of a suspected CCI was made in the prehospital setting based on hetero anamnestic data, physical examination findings and ST-segment elevation. At the hospital, additional testing (MDCT of the endocranium, echocardiogram and high troponin levels) confirmed both diagnoses. The patient was treated with fibrinolytic therapy but developed cardiac arrest. After extensive CPR efforts, the patient was pronounced dead. Conclusion: It is necessary to create national guidelines for the diagnosis and treatment of this emergency condition as soon as possible. In the meantime, an individualized approach to each patient is the best policy.
Keywords	acute myocardial infarction ; acute cerebral infarction ; cci ; Medicine (General) ; R5-920
Subject code	610
Language	English
Publishing date	2021-01-01T00:00:00Z
Publisher	City Medical emergency department, Belgrade
Document type	Article ; Online
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Article ; Online: Evaluation of beta cell function in newly diagnosed type 2 diabetes mellitus in clinical practice

Stojanović Jelena / Beljić-Živković Teodora

Medicinski Podmladak, Vol 74, Iss 1, Pp 18-

2023 Volume 24

Abstract: Dysfunctions underlining type 2 diabetes mellitus (DM2) evolution are insulin resistance and beta-cell secretory insufficiency. Practical but reliable beta-cell function (BCF) testing is still elusive. Methods of BCF measurement include the homeostasis ... ...

Abstract	Dysfunctions underlining type 2 diabetes mellitus (DM2) evolution are insulin resistance and beta-cell secretory insufficiency. Practical but reliable beta-cell function (BCF) testing is still elusive. Methods of BCF measurement include the homeostasis model assessment (HOMA), glucagon stimulation test (GST), oral glucose tolerance tests (OGTT), intravenous glucose tolerance tests (IVGTT), meal tolerance tests (MTT) and the hyperglycemic clamp procedure. Oral tests have the advantage of simpler use and superior approximation of real-life stimulation inclusive for incretin activation effects. The advantage of the test meal over the OGTT incudes a more adequate simulation of nutrients effect on incretin secretion. Therefore, a standardized test meal (STO) would best reflect the spike in insulin secretion after a meal in real life. Conclusion: Standardized test meal, as potent stimulus of C-peptide secretion, is a promising simple and naturalistic alternative to in vivo assess beta-cell function in an affordable outpatient setting, through analysis of C-peptide response in newly diagnosed diabetic patients, as potent stimulus of C-peptide secretion.
Keywords	standardized test meal ; beta-cell dysfunction ; diabetes mellitus type 2 ; Medicine ; R
Language	English
Publishing date	2023-01-01T00:00:00Z
Publisher	University of Belgrade, Medical Faculty
Document type	Article ; Online
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Article ; Online: Considering ABO Incompatible Living Donor Kidney Transplantation Before Deceased Donor Kidney Transplantation in Children: A Letter to the Editor.

Paessler, Alicia / Stojanovic, Jelena

Transplant international : official journal of the European Society for Organ Transplantation

2023 Volume 36, Page(s) 11613

MeSH term(s)	Humans ; Child ; Living Donors ; Kidney Transplantation ; Kidney ; Graft Rejection ; ABO Blood-Group System ; Blood Group Incompatibility ; Graft Survival
Chemical Substances	ABO Blood-Group System
Language	English
Publishing date	2023-09-18
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	639435-8
ISSN	1432-2277 ; 0934-0874
ISSN (online)	1432-2277
ISSN	0934-0874
DOI	10.3389/ti.2023.11613
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Article ; Online: Management of pediatric patients with a failing kidney transplant: A survey of UK-based renal units.

Letts, Matthew / Arslan, Zainab / Plumb, Lucy / Bailey, Pippa / Griffin, Siân / Stojanovic, Jelena

Pediatric transplantation

2024 Volume 28, Issue 2, Page(s) e14730

MeSH term(s)	Humans ; Child ; Kidney Transplantation ; Kidney ; Surveys and Questionnaires ; United Kingdom
Language	English
Publishing date	2024-03-04
Publishing country	Denmark
Document type	Letter
ZDB-ID	1390284-2
ISSN	1399-3046 ; 1397-3142
ISSN (online)	1399-3046
ISSN	1397-3142
DOI	10.1111/petr.14730
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Article ; Online: The clinical and radiological cerebrovascular abnormalities associated with renovascular hypertension in children: a systematic review.

Mudalige, Nadeesha L / Ranasinghe, Chavini / Stojanovic, Jelena

Pediatric nephrology (Berlin, Germany)

2021 Volume 37, Issue 1, Page(s) 49–59

Abstract: Renovascular disease is an important secondary cause of hypertension in childhood. In this cohort, many may have undiagnosed cerebrovascular disease, and some children present acutely with cerebrovascular complications. However, these associations are ... ...

Abstract	Renovascular disease is an important secondary cause of hypertension in childhood. In this cohort, many may have undiagnosed cerebrovascular disease, and some children present acutely with cerebrovascular complications. However, these associations are yet to be defined in the literature.A systematic review of clinical and radiological abnormalities associated with renovascular hypertension in the global pediatric (< 18 years) population. The MEDLINE, Embase, and Google Scholar databases were searched, from database inception to 26 January 2021. Primary articles were unrestricted by study design and geographical location but were limited to those published in English.A total of 303 individuals (median age: 7.6 years [range 10 days-17.9 years]; M:F, 174:129) from 34 studies were included, across 13 countries. Twenty-seven individual cases were published for children with coexisting renovascular hypertension and cerebrovascular disease. Most children had bilateral renal artery stenosis, secondary to fibromuscular dysplasia and had coexisting occlusive cerebrovascular disease. The majority presented with neurological symptoms, and cerebral complication ranged from asymptomatic cerebrovascular stenosis to acute stroke and posterior reversible encephalopathy syndrome. The location or underlying etiology of the renovascular disease did not predict the location or extent of the cerebrovascular disease. The evidence from the cohort studies was limited, as none specifically established a cohort of children with coexisting disease. Furthermore, the conclusions drawn were subjected to considerable bias from the treating clinicians.A prospective cohort of children with renovascular hypertension and cerebrovascular complications should be established so the long-term prognosis and impact of treatment may be better understood.
MeSH term(s)	Cerebrovascular Disorders/complications ; Cerebrovascular Disorders/diagnostic imaging ; Child ; Humans ; Hypertension, Renovascular/diagnostic imaging ; Hypertension, Renovascular/etiology ; Radiology
Language	English
Publishing date	2021-07-08
Publishing country	Germany
Document type	Journal Article ; Review ; Systematic Review
ZDB-ID	631932-4
ISSN	1432-198X ; 0931-041X
ISSN (online)	1432-198X
ISSN	0931-041X
DOI	10.1007/s00467-021-05165-x
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Article ; Online: Diagnosis and Treatment of Renovascular Disease in Children.

Patel, Premal A / Stojanovic, Jelena

Seminars in roentgenology

2019 Volume 54, Issue 4, Page(s) 367–383

MeSH term(s)	Child ; Endovascular Procedures ; Humans ; Kidney Diseases/diagnostic imaging ; Kidney Diseases/therapy ; Radiography, Interventional ; Vascular Diseases/diagnostic imaging ; Vascular Diseases/therapy
Language	English
Publishing date	2019-06-26
Publishing country	United States
Document type	Journal Article ; Review
ZDB-ID	80310-8
ISSN	1558-4658 ; 0037-198X
ISSN (online)	1558-4658
ISSN	0037-198X
DOI	10.1053/j.ro.2019.06.007
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Article ; Online: Safety, efficacy, and timing of transplantation(s) in propionic and methylmalonic aciduria.

Chakrapani, Anupam / Stojanovic, Jelena / Vara, Roshni / De Nictolis, Francesca / Spada, Marco / Dionisi-Vici, Carlo

Journal of inherited metabolic disease

2023 Volume 46, Issue 3, Page(s) 466–481

Abstract: Propionic (PA) and methylmalonic aciduria (MMA) share many clinical similarities, which include the risk of acute metabolic encephalopathies, and some long-term complications, such as optic neuropathy, pancreatic involvement, developmental disability, ... ...

Abstract	Propionic (PA) and methylmalonic aciduria (MMA) share many clinical similarities, which include the risk of acute metabolic encephalopathies, and some long-term complications, such as optic neuropathy, pancreatic involvement, developmental disability, and similar management approaches, but they also represent distinct clinical and biochemical entities. In the severe forms of PA and MMA, most long-term complications cannot be prevented with conventional clinical management. Organ transplantation represents a form of partial enzyme replacement to improve the long-term outlook for these disorders. There is evidence that early liver transplant in both disorders greatly improves metabolic stability and reduces the risk of long-term complications. For MMA, early liver transplant reduces methylmalonic acid levels which in turns reduces its effects on kidneys, and therefore slows progression of chronic kidney disease. However, established organ damage cannot be reversed. For patients with MMA who present with chronic kidney disease, consideration should be given for combined liver and kidney transplants. Transplantation in PA and MMA carries a high risk of complications and requires highly specialised pre-operative and peri-operative management. Involvement of a multidisciplinary team is essential and should include metabolic team, nephrologist, hepatologist, hepatobiliary and renal transplant surgeons, anaesthesiologists, cardiologists, intensive care team, dieticians and specialist nurses. These patients require life-long multidisciplinary follow-up. There is increasing evidence in the literature on excellent short to medium-term patient and allograft survival following transplantation when patients are managed by a multidisciplinary team in a specialist centre. Improved early diagnosis and reductions in transplant-related mortality and morbidity have allowed early transplantation to be used electively to further improve the outcome.
MeSH term(s)	Humans ; Amino Acid Metabolism, Inborn Errors/diagnosis ; Liver Transplantation ; Kidney Transplantation/adverse effects ; Renal Insufficiency, Chronic/complications ; Methylmalonic Acid ; Propionic Acidemia/diagnosis
Chemical Substances	Methylmalonic Acid (8LL8S712J7)
Language	English
Publishing date	2023-04-24
Publishing country	United States
Document type	Journal Article ; Review ; Research Support, Non-U.S. Gov't
ZDB-ID	438341-2
ISSN	1573-2665 ; 0141-8955
ISSN (online)	1573-2665
ISSN	0141-8955
DOI	10.1002/jimd.12613
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Article ; Online: The cyclical character of economic policy in Serbia 2001-2012

Radović-Stojanović Jelena

Economic Annals, Vol 59, Iss 202, Pp 157-

2014 Volume 182

Abstract: This paper investigates the cyclical character of economic policy in Serbia in the period 2001-2012. For this purpose the cyclical movement of the following monetary and fiscal variables have been analysed: M2 money supply, the retail price index, the ... ...

Abstract	This paper investigates the cyclical character of economic policy in Serbia in the period 2001-2012. For this purpose the cyclical movement of the following monetary and fiscal variables have been analysed: M2 money supply, the retail price index, the consumer price index, and the real effective exchange rate as the monetary policy indicators, and budget revenues and budget expenditures as the fiscal policy indicators. In the evaluation of the cyclical character of the economic policy, cross-correlation between the cyclical component of economic policy indicators and the gross domestic product at various lags has been observed. The results of cross-correlation analysis suggest that the budget expenditures are countercyclical and lead the aggregate cycle while the budget revenues are procyclical. The cyclical character of M2 money supply in the Serbian economy is somewhat contradictory, so further investigations of the cyclical character of monetary policy and mutual interdependence of money and output are required. The real effective exchange rate is countercyclical. The prices are procyclical and lag behind the cycles in aggregate economic activity. The procyclical character of prices indicates that the causes of the cyclical fluctuations of aggregate economic activities in Serbia in the period from 2001 to 2012 were on the demand side.
Keywords	growth cycles ; counter cyclical economic policy ; Serbia ; Economic theory. Demography ; HB1-3840 ; Social Sciences ; H
Subject code	339
Language	English
Publishing date	2014-01-01T00:00:00Z
Publisher	Faculty of Economics, Belgrade
Document type	Article ; Online
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Article ; Online: Psychological Concerns of Children Undergoing Kidney Transplantation During the Pandemic: Single-centre Experience.

Paessler, Alicia / Boyle, Sheila / Marks, Stephen / Kessaris, Nicos / Stojanovic, Jelena

BMJ paediatrics open

2021 Volume 5, Issue 1, Page(s) e001174

Abstract: Many paediatric kidney transplant programmes were closed during the COVID-19 pandemic, and due to the vulnerable nature of patients with end-stage kidney disease (ESKD), there were new concerns once these programmes reopened. We surveyed children and ... ...

Abstract	Many paediatric kidney transplant programmes were closed during the COVID-19 pandemic, and due to the vulnerable nature of patients with end-stage kidney disease (ESKD), there were new concerns once these programmes reopened. We surveyed children and families who received a kidney transplant during the pandemic. We found that half of the participants felt scared and/or anxious about receiving a kidney transplant during the pandemic, and 2/8 participants were worried about catching COVID-19 during their recovery. While detailed counselling and additional safety precautions contributed to a good experience, patients and parents still demonstrated fear towards transplantation.
MeSH term(s)	COVID-19 ; Child ; Humans ; Kidney Failure, Chronic/epidemiology ; Kidney Transplantation/adverse effects ; Pandemics ; SARS-CoV-2
Language	English
Publishing date	2021-07-29
Publishing country	England
Document type	Journal Article
ISSN	2399-9772
ISSN (online)	2399-9772
DOI	10.1136/bmjpo-2021-001174
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Article ; Online: Pediatric renal transplantation-A UNOS database analysis of donor-recipient size mismatch.

Kostakis, Ioannis D / Chandak, Pankaj / Assia-Zamora, Sergio / Gogalniceanu, Petrut / Loukopoulos, Ioannis / Calder, Francis / Stojanovic, Jelena / Kessaris, Nicos

Pediatric transplantation

2023 Volume 27, Issue 3, Page(s) e14470

Abstract: Background: We used the BSAi (Donor BSA/Recipient BSA) to assess whether transplanting a small or large kidney into a pediatric recipient relative to his/her size influences renal transplant outcomes.: Methods: We included 14 322 single-kidney ... ...

Abstract	Background: We used the BSAi (Donor BSA/Recipient BSA) to assess whether transplanting a small or large kidney into a pediatric recipient relative to his/her size influences renal transplant outcomes. Methods: We included 14 322 single-kidney transplants in pediatric recipients (0-17 years old) (01/2000-02/2020) from the United Network for Organ Sharing database. We divided cases into four BSAi groups (BSAi ≤ 1, 1 < BSAi ≤ 2, 2 < BSAi ≤ 3, BSAi > 3). Results: There were no differences concerning delayed graft function (DGF) or primary non-function (PNF) rates, whether the grafts were from living or brain-dead donors. In both transplants coming from living donors and brain-dead donors, cases with BSAi > 3 and cases with 2 < BSAi ≤ 3 had similar graft survival (p = .13 for transplants from living donors, p = .413 for transplants from brain-dead donors), and both groups had longer graft survival than cases with 1 < BSAi ≤ 2 and cases with BSAi ≤ 1 (p < .001). The difference in 10-year graft survival rates between cases with BSAi > 3 and cases with BSAi ≤ 1 reached around 25% in both donor types. The better graft survival in transplants with BSAi > 2 was confirmed in multivariable analysis. Conclusions: There is no significant impact of donor-recipient size mismatch on DGF and PNF rates in pediatric renal transplants. However, graft survival is significantly improved when the donor's size is more than twice the pediatric recipient's size.
MeSH term(s)	Humans ; Child ; Male ; Female ; Infant, Newborn ; Infant ; Child, Preschool ; Adolescent ; Kidney Transplantation ; Tissue Donors ; Living Donors ; Kidney Diseases ; Graft Survival ; Survival Rate ; Brain Death ; Registries
Language	English
Publishing date	2023-01-18
Publishing country	Denmark
Document type	Journal Article
ZDB-ID	1390284-2
ISSN	1399-3046 ; 1397-3142
ISSN (online)	1399-3046
ISSN	1397-3142
DOI	10.1111/petr.14470
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