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  1. Article ; Online: Sleep and Risk of Pancreatic Cancer in the UK Biobank.

    Freeman, Joshua R / Saint-Maurice, Pedro F / Zhang, Ting / Matthews, Charles E / Stolzenberg-Solomon, Rachael Z

    Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology

    2024  Volume 33, Issue 4, Page(s) 624–627

    Abstract: Background: Light at night, which may cause circadian disruption, is a potential pancreatic cancer risk factor. However, evidence from related exposures such as poor sleep health and shift work remains inconclusive and sparsely investigated.: Methods!# ...

    Abstract Background: Light at night, which may cause circadian disruption, is a potential pancreatic cancer risk factor. However, evidence from related exposures such as poor sleep health and shift work remains inconclusive and sparsely investigated.
    Methods: We evaluated associations between self-reported typical sleep duration, chronotype, shift work, insomnia symptoms, snoring, and daytime sleeping and pancreatic ductal adenocarcinomas (PDAC) incidence among 475,286 UK Biobank participants. We used Cox proportional hazards models to estimate HRs and 95% confidence intervals (CI) adjusting for age, sex, body mass index, smoking status, duration, and frequency, alcohol intake, diabetes status, race, and employment/shift work.
    Results: Over 14 years of follow-up, 1,079 adults were diagnosed with PDAC. There were no associations observed between sleep characteristics, including sleep duration [<7 vs. 7-<9 hours; HR, 1.03; 95% CI, 0.90-1.19; ≥9 hours; HR, 1.00 (0.81-1.24), evening chronotype ("definitely" an evening person vs. "definitely" a morning person; HR, 0.99 (0.77-1.29)], shift work, insomnia symptoms, snoring, or daytime sleep and PDAC risk.
    Conclusions: Self-reported typical sleep characteristics and shift work were not associated with PDAC risk.
    Impact: Considering the role of light at night and shift work in circadian disruption and cancer risk, it is plausible that poor sleep health among a general population may be related to cancer risk through similar sleep and circadian disrupting processes. This work may suggest that typical sleep characteristics and shift work are not associated with PDAC, although additional work is needed to confirm these findings.
    MeSH term(s) Adult ; Humans ; Sleep Initiation and Maintenance Disorders/complications ; Sleep Initiation and Maintenance Disorders/epidemiology ; Biological Specimen Banks ; Snoring ; UK Biobank ; Work Schedule Tolerance ; Sleep ; Circadian Rhythm ; Risk Factors ; Pancreatic Neoplasms/epidemiology ; Pancreatic Neoplasms/etiology
    Language English
    Publishing date 2024-02-21
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1153420-5
    ISSN 1538-7755 ; 1055-9965
    ISSN (online) 1538-7755
    ISSN 1055-9965
    DOI 10.1158/1055-9965.EPI-23-0983
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Light at Night and Risk of Pancreatic Cancer in the NIH-AARP Diet and Health Study.

    Xiao, Qian / Jones, Rena R / James, Peter / Stolzenberg-Solomon, Rachael Z

    Cancer research

    2021  Volume 81, Issue 6, Page(s) 1616–1622

    Abstract: Circadian disruption may play a role in carcinogenesis. Recent research suggests that light at night (LAN), a circadian disruptor, may be a risk factor for cancer. Moreover, LAN has been linked to obesity and diabetes, two risk factors for pancreatic ... ...

    Abstract Circadian disruption may play a role in carcinogenesis. Recent research suggests that light at night (LAN), a circadian disruptor, may be a risk factor for cancer. Moreover, LAN has been linked to obesity and diabetes, two risk factors for pancreatic ductal adenocarcinoma (PDAC). Here we examine the relationship between LAN and PDAC in an epidemiologic study of 464,371 participants from the NIH-AARP Diet and Health Study. LAN was estimated from satellite imagery at baseline (1996), and incident primary PDAC cases were ascertained from state cancer registries. Cox proportional hazards models were used to estimate HRs and two-sided 95% confidence intervals (CI) for the association between quintiles of LAN and PDAC in the overall population stratified by sex. Over up to 16.2 years of follow-up, a total of 2,502 incident PDAC were identified in the cohort. Higher estimated LAN exposure was associated with an elevated PDAC risk. Compared with those living in areas in the lowest LAN quintile, those in areas in the highest quintile had a 27% increase PDAC risk [HR (95% CI), 1.24 (1.03-1.49)], with similar risk for men [1.21 (0.96-1.53)] and women [1.28 (0.94-1.75)]. In addition, stronger associations were observed in normal and overweight groups compared with the obese group (
    MeSH term(s) Aged ; Carcinoma, Pancreatic Ductal/epidemiology ; Carcinoma, Pancreatic Ductal/etiology ; Circadian Clocks/physiology ; Circadian Clocks/radiation effects ; Circadian Rhythm/physiology ; Circadian Rhythm/radiation effects ; Female ; Follow-Up Studies ; Humans ; Incidence ; Lighting/adverse effects ; Lighting/statistics & numerical data ; Male ; Middle Aged ; Obesity/epidemiology ; Overweight/epidemiology ; Pancreatic Neoplasms/epidemiology ; Pancreatic Neoplasms/etiology ; Photoperiod ; Risk Assessment/statistics & numerical data ; Risk Factors ; United States/epidemiology
    Language English
    Publishing date 2021-01-29
    Publishing country United States
    Document type Journal Article ; Observational Study ; Research Support, N.I.H., Extramural ; Research Support, N.I.H., Intramural
    ZDB-ID 1432-1
    ISSN 1538-7445 ; 0008-5472
    ISSN (online) 1538-7445
    ISSN 0008-5472
    DOI 10.1158/0008-5472.CAN-20-2256
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Nested Case-Control Studies Investigating Serum Perfluorooctanoate and Perfluorooctane Sulfonate Levels and Pancreatic Ductal Adenocarcinoma in Two Cohorts.

    Zhang, Ting / Fu, Sheng / Yu, Kai / Albanes, Demetrius / Moore, Steven C / Purdue, Mark P / Stolzenberg-Solomon, Rachael Z

    Environmental health perspectives

    2023  Volume 131, Issue 10, Page(s) 107702

    MeSH term(s) Humans ; Fluorocarbons ; Caprylates ; Case-Control Studies ; Adenocarcinoma ; Alkanesulfonic Acids ; Pancreatic Neoplasms/epidemiology
    Chemical Substances perfluorooctane (6P60ZBK0QL) ; perfluorooctanoic acid (947VD76D3L) ; Fluorocarbons ; Caprylates ; Alkanesulfonic Acids
    Language English
    Publishing date 2023-10-16
    Publishing country United States
    Document type Journal Article
    ZDB-ID 195189-0
    ISSN 1552-9924 ; 0091-6765 ; 1078-0475
    ISSN (online) 1552-9924
    ISSN 0091-6765 ; 1078-0475
    DOI 10.1289/EHP13208
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  4. Article ; Online: Dietary Quality and Circulating Lipidomic Profiles in 2 Cohorts of Middle-Aged and Older Male Finnish Smokers and American Populations.

    Zhang, Ting / Naudin, Sabine / Hong, Hyokyoung G / Albanes, Demetrius / Männistö, Satu / Weinstein, Stephanie J / Moore, Steven C / Stolzenberg-Solomon, Rachael Z

    The Journal of nutrition

    2023  Volume 153, Issue 8, Page(s) 2389–2400

    Abstract: Background: Higher dietary quality is associated with lower disease risks and has not been examined extensively with lipidomic profiles.: Objectives: Our goal was to examine associations of the Healthy Eating Index (HEI)-2015, Alternate HEI-2010 ( ... ...

    Abstract Background: Higher dietary quality is associated with lower disease risks and has not been examined extensively with lipidomic profiles.
    Objectives: Our goal was to examine associations of the Healthy Eating Index (HEI)-2015, Alternate HEI-2010 (AHEI-2010), and alternate Mediterranean Diet Index (aMED) diet quality indices with serum lipidomic profiles.
    Methods: We conducted a cross-sectional analysis of HEI-2015, AHEI-2010, and aMED with lipidomic profiles from 2 nested case-control studies within the Prostate, Lung, Colorectal and Ovarian Cancer Screening Trial (n = 627) and the Alpha-Tocopherol, Beta-Carotene Cancer Prevention Study (n = 711). We used multivariable linear regression to determine associations of the indices, derived from baseline food-frequency questionnaires (Prostate, Lung, Colorectal and Ovarian Cancer Screening Trial: 1993-2001, Alpha-Tocopherol, Beta-Carotene Cancer Prevention Study: 1985-1988) with serum concentrations of 904 lipid species and 252 fatty acids (FAs) across 15 lipid classes and 28 total FAs, within each cohort and meta-analyzed results using fixed-effect models for lipids significant at Bonferroni-corrected threshold in common in both cohorts.
    Results: Adherence to HEI-2015, AHEI-2010, or aMED was associated positively with 31, 41, and 54 lipid species and 8, 6, and 10 class-specific FAs and inversely with 2, 8, and 34 lipid species and 1, 3, and 5 class-specific FAs, respectively. Twenty-five lipid species and 5 class-specific FAs were common to all indices, predominantly triacylglycerols, FA22:6 [docosahexaenoic acid (DHA)]-containing species, and DHA. All indices were positively associated with total FA22:6. AHEI-2010 and aMED were inversely associated with total FA18:1 (oleic acid) and total FA17:0 (margaric acid), respectively. The identified lipids were most associated with components of seafood and plant proteins and unsaturated:saturated fat ratio in HEI-2015; eicosapentaenoic acid plus DHA in AHEI-2010; and fish and monounsaturated:saturated fat ratio in aMED.
    Conclusions: Adherence to HEI-2015, AHEI-2010, and aMED is associated with serum lipidomic profiles, mostly triacylglycerols or FA22:6-containing species, which are related to seafood and plant proteins, eicosapentaenoic acid-DHA, fish, or fat ratio index components.
    MeSH term(s) Male ; Animals ; United States ; Humans ; Female ; Lipidomics ; Smokers ; Finland ; Cross-Sectional Studies ; alpha-Tocopherol ; beta Carotene ; Eicosapentaenoic Acid ; Diet ; Diet, Mediterranean ; Triglycerides ; Colorectal Neoplasms ; Ovarian Neoplasms
    Chemical Substances alpha-Tocopherol (H4N855PNZ1) ; beta Carotene (01YAE03M7J) ; Eicosapentaenoic Acid (AAN7QOV9EA) ; Triglycerides
    Language English
    Publishing date 2023-06-14
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Intramural
    ZDB-ID 218373-0
    ISSN 1541-6100 ; 0022-3166
    ISSN (online) 1541-6100
    ISSN 0022-3166
    DOI 10.1016/j.tjnut.2023.06.010
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Hemochromatosis, Iron Overload-Related Diseases, and Pancreatic Cancer Risk in the Surveillance, Epidemiology, and End Results (SEER)-Medicare.

    Julián-Serrano, Sachelly / Yuan, Fangcheng / Barrett, Michael J / Pfeiffer, Ruth M / Stolzenberg-Solomon, Rachael Z

    Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology

    2021  Volume 30, Issue 11, Page(s) 2136–2139

    Abstract: Background: Experimental studies suggest that iron overload might increase pancreatic cancer risk. We evaluated whether prediagnostic hemochromatosis and iron-overload diseases, including sideroblastic and congenital dyserythropoietic anemias, and non- ... ...

    Abstract Background: Experimental studies suggest that iron overload might increase pancreatic cancer risk. We evaluated whether prediagnostic hemochromatosis and iron-overload diseases, including sideroblastic and congenital dyserythropoietic anemias, and non-alcoholic-related chronic liver disease (NACLD) were associated with pancreatic cancer risk in older adults.
    Methods: We conducted a population-based, case-control study within the U.S. Surveillance, Epidemiology, and End Results Program (SEER)-Medicare linked data. Incident primary pancreatic cancer cases were adults > 66 years. Controls were alive at the time cases were diagnosed and matched to cases (4:1 ratio) by age, sex, and calendar year. Hemochromatosis, iron-overload anemias, and NACLD were reported 12 or more months before pancreatic cancer diagnosis or control selection using Medicare claims data. Adjusted unconditional logistic regression models were used to calculate ORs and 95% confidence intervals (CI) between hemochromatosis, sideroblastic and congenital dyserythropoietic anemias, NACLD, and pancreatic cancer.
    Results: Between 1992 and 2015, 80,074 pancreatic cancer cases and 320,296 controls were identified. Overall, we did not observe statistically significant associations between hemochromatosis, sideroblastic anemia, or congenital dyserythropoietic anemia and pancreatic cancer; however, sideroblastic anemia was associated with later primary pancreatic cancer (OR, 1.30; 95% CI, 1.03-1.64). NACLD was associated with first (OR, 1.10; 95% CI, 1.01-1.19), later (OR, 1.17; 95% CI, 1.02-1.35), and all (OR, 1.12; 95% CI, 1.04-1.20) pancreatic cancer.
    Conclusions: Overall hemochromatosis and iron-overload anemias were not associated with pancreatic cancer, whereas NACLD was associated with increased risk in this large study of older adults.
    Impact: These results partly support the hypothesis that iron-overload diseases increase pancreatic cancer risk.
    MeSH term(s) Age Factors ; Aged ; Aged, 80 and over ; Case-Control Studies ; Causality ; Female ; Hemochromatosis/epidemiology ; Humans ; Male ; Medicare/statistics & numerical data ; Pancreatic Neoplasms/epidemiology ; Population Surveillance ; SEER Program/statistics & numerical data ; United States/epidemiology
    Language English
    Publishing date 2021-09-03
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1153420-5
    ISSN 1538-7755 ; 1055-9965
    ISSN (online) 1538-7755
    ISSN 1055-9965
    DOI 10.1158/1055-9965.EPI-21-0476
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Autoimmune conditions and pancreatic cancer risk in older American adults.

    Yuan, Fangcheng / Pfeiffer, Ruth M / Julián-Serrano, Sachelly / Arjani, Simran / Barrett, Michael J / Koshiol, Jill / Stolzenberg-Solomon, Rachael Z

    International journal of cancer

    2022  Volume 152, Issue 2, Page(s) 172–182

    Abstract: Pancreatic cancer (PC) is highly fatal, and its incidence is increasing in the United States. Population-based registry studies suggest associations between a few autoimmune conditions and PC risk, albeit based on a relatively small number of cases. We ... ...

    Abstract Pancreatic cancer (PC) is highly fatal, and its incidence is increasing in the United States. Population-based registry studies suggest associations between a few autoimmune conditions and PC risk, albeit based on a relatively small number of cases. We conducted a population-based, nested case-control study to examine the associations between autoimmune conditions and PC risk within the Surveillance, Epidemiology, and End Results Program (SEER)-Medicare population. Incident primary malignant PC cases (n = 80 074) were adults ≥66 years and diagnosed between 1992 and 2015. Controls (n = 320 296) were alive at the time cases were diagnosed and frequency-matched to cases (4:1 ratio) by age, sex, and year of diagnosis. We used multivariable-adjusted, unconditional logistic regression to calculate odds ratios (ORs) and 95% confidence intervals (CIs) for 45 autoimmune conditions identified from Medicare claims. Eight autoimmune conditions including ankylosing spondylitis (OR = 1.45; 95% CI: 1.14-1.84), Graves' disease (OR = 1.18; 95% CI: 1.03-1.34), localized scleroderma (OR = 1.27; 95% CI: 1.06-1.52), pernicious anemia (OR = 1.08; 95% CI: 1.02-1.14), primary sclerosing cholangitis (OR = 1.37; 95% CI: 1.18-1.59), pure red cell aplasia (OR = 1.31; 95% CI: 1.16-1.47), type 1 diabetes (OR = 1.11; 95% CI: 1.07-1.15), and ulcerative colitis (OR = 1.18; 95% CI: 1.07-1.31) were associated with increased PC risk (false discovery rate-adjusted P values <.10). In subtype analyses, these conditions were associated with pancreatic ductal adenocarcinoma, whereas only ulcerative colitis was associated with pancreatic neuroendocrine tumors. Our results support the hypothesis that autoimmune conditions may play a role in PC development.
    MeSH term(s) Humans ; Aged ; Adult ; United States/epidemiology ; Case-Control Studies ; Colitis, Ulcerative ; Medicare ; Pancreas ; Pancreatic Neoplasms/epidemiology ; Pancreatic Neoplasms/etiology ; Autoimmune Diseases/complications ; Autoimmune Diseases/epidemiology ; Pancreatic Neoplasms
    Language English
    Publishing date 2022-09-05
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Intramural
    ZDB-ID 218257-9
    ISSN 1097-0215 ; 0020-7136
    ISSN (online) 1097-0215
    ISSN 0020-7136
    DOI 10.1002/ijc.34235
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  7. Article ; Online: Is the Women's Health Initiative (WHI) Dietary Modification Associated With a Reduced Risk of Pancreatic Cancer?

    Stolzenberg-Solomon, Rachael Z / Katki, Hormuzd A

    Journal of the National Cancer Institute

    2017  Volume 110, Issue 1

    MeSH term(s) Diet, Fat-Restricted ; Female ; Humans ; Pancreatic Neoplasms ; Women's Health
    Language English
    Publishing date 2017-09-15
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 2992-0
    ISSN 1460-2105 ; 0027-8874 ; 0198-0157
    ISSN (online) 1460-2105
    ISSN 0027-8874 ; 0198-0157
    DOI 10.1093/jnci/djx139
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  8. Article ; Online: Epidemiology and Inherited Predisposition for Sporadic Pancreatic Adenocarcinoma.

    Stolzenberg-Solomon, Rachael Z / Amundadottir, Laufey T

    Hematology/oncology clinics of North America

    2015  Volume 29, Issue 4, Page(s) 619–640

    Abstract: Given the changing demographics of Western populations, the numbers of pancreatic cancer cases are projected to increase during the next decade. Diabetes, recent cigarette smoking, and excess body weight are the cancer's most consistent risk factors. The ...

    Abstract Given the changing demographics of Western populations, the numbers of pancreatic cancer cases are projected to increase during the next decade. Diabetes, recent cigarette smoking, and excess body weight are the cancer's most consistent risk factors. The search for common and rare germline variants that influence risk of pancreatic cancer through genome-wide association studies and high-throughput-sequencing-based studies is underway and holds the promise of increasing the knowledge of variants and genes that play a role in inherited susceptibility of this disease. Research reported in this review has advanced the understanding of pancreatic cancer.
    MeSH term(s) Adenocarcinoma/epidemiology ; Adenocarcinoma/genetics ; Animals ; Genetic Predisposition to Disease ; Genome-Wide Association Study ; Humans ; Incidence ; Pancreatic Neoplasms/epidemiology ; Pancreatic Neoplasms/genetics ; Risk Factors ; United States/epidemiology
    Language English
    Publishing date 2015-07-31
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Intramural ; Review
    ZDB-ID 93115-9
    ISSN 1558-1977 ; 0889-8588
    ISSN (online) 1558-1977
    ISSN 0889-8588
    DOI 10.1016/j.hoc.2015.04.009
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  9. Article ; Online: Prediagnostic Serum Vitamin D, Vitamin D Binding Protein Isoforms, and Cancer Survival.

    Weinstein, Stephanie J / Mondul, Alison M / Layne, Tracy M / Yu, Kai / Huang, Jiaqi / Stolzenberg-Solomon, Rachael Z / Ziegler, Regina G / Purdue, Mark P / Huang, Wen-Yi / Abnet, Christian C / Freedman, Neal D / Albanes, Demetrius

    JNCI cancer spectrum

    2022  Volume 6, Issue 2

    Abstract: Background: Higher circulating vitamin D has been associated with improved overall cancer survival, but data for organ-specific cancers are mixed.: Methods: We examined the association between prediagnostic serum 25-hydroxyvitamin D [25(OH)D], the ... ...

    Abstract Background: Higher circulating vitamin D has been associated with improved overall cancer survival, but data for organ-specific cancers are mixed.
    Methods: We examined the association between prediagnostic serum 25-hydroxyvitamin D [25(OH)D], the recognized biomarker of vitamin D status, and cancer survival in 4038 men and women diagnosed with 1 of 11 malignancies during 22 years of follow-up (median = 15.6 years) within the Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial. Multivariable-adjusted proportional hazards regression estimated hazard ratios (HR) and 95% confidence intervals (CI) for associations between baseline 25(OH)D concentration and subsequent cancer survival; we also stratified on the common vitamin D binding protein isoforms (Gc1f, Gc1s, and Gc2) defined by two single-nucleotide polymorphisms (rs7041 and rs4588) in the vitamin D binding protein gene GC. All P values were 2-sided.
    Results: Higher 25(OH)D concentrations were associated with greater overall cancer survival (HR for cancer mortality = 0.83, 95% CI = 0.70 to 0.98 for highest vs lowest quintile; Ptrend = .05) and lung cancer survival (HR = 0.63, 95% CI = 0.44 to 0.90; Ptrend = .03). These associations were limited to cases expressing the Gc2 isoform (HR = 0.38 for Gc2-2, 95% CI = 0.14 to 1.05 for highest vs lowest quintile; Ptrend = .02; and HR = 0.30 for Gc1-2/Gc2-2 combined, 95% CI = 0.16 to 0.56; Ptrend < .001 for overall and lung cancer, respectively).
    Conclusions: Higher circulating 25(OH)D was associated with improved overall and lung cancer survival. As this was especially evident among cases with the genetically determined Gc2 isoform of vitamin D binding protein, such individuals may gain a cancer survival advantage by maintaining higher 25(OH)D blood concentrations.
    MeSH term(s) Female ; Humans ; Lung Neoplasms/genetics ; Male ; Polymorphism, Single Nucleotide ; Protein Isoforms/genetics ; Vitamin D ; Vitamin D-Binding Protein/genetics
    Chemical Substances Protein Isoforms ; Vitamin D-Binding Protein ; Vitamin D (1406-16-2)
    Language English
    Publishing date 2022-05-22
    Publishing country England
    Document type Journal Article ; Research Support, N.I.H., Intramural
    ISSN 2515-5091
    ISSN (online) 2515-5091
    DOI 10.1093/jncics/pkac019
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  10. Article ; Online: Vitamin D and pancreatic cancer.

    Stolzenberg-Solomon, Rachael Z

    Annals of epidemiology

    2008  Volume 19, Issue 2, Page(s) 89–95

    Abstract: Sun exposure has been associated with lower death rates for pancreatic cancer in ecological studies. Skin exposure to solar ultraviolet B radiation induces cutaneous production of precursors to 25-hydroxy (OH) vitamin D (D) and is considered the primary ... ...

    Abstract Sun exposure has been associated with lower death rates for pancreatic cancer in ecological studies. Skin exposure to solar ultraviolet B radiation induces cutaneous production of precursors to 25-hydroxy (OH) vitamin D (D) and is considered the primary contributor to vitamin D status in most populations. Pancreatic islet and duct cells express 25-(OH) D(3)-1alpha-hydroxylase that generates the biologically active 1,25-dihydroxy(OH)(2) D form. Thus, 25(OH)D concentrations could affect pancreatic function and possibly pancreatic cancer etiology. Serum 25-(OH)D is the major circulating vitamin D metabolite and is considered the best indicator of vitamin D status as determined by the sun and diet. Although recent prospective epidemiologic studies of higher predicted vitamin D status score and vitamin D intake and pancreatic cancer risk suggest protective associations, a nested case-control study showed a significant 3-fold increased risk for pancreatic cancer with higher vitamin D status. Limitations of these studies include the former do not measure vitamin D status on pancreatic cancer cases and the later was conducted in a male smoker population. More research is needed, particularly examination of pre-diagnostic vitamin D status and risk of pancreatic cancer, prior to conclusions for vitamin D's potential role in the etiology of this highly fatal cancer.
    MeSH term(s) Humans ; Male ; Pancreatic Neoplasms/blood ; Pancreatic Neoplasms/epidemiology ; Vitamin D/administration & dosage ; Vitamin D/analogs & derivatives ; Vitamin D/blood
    Chemical Substances Vitamin D (1406-16-2) ; 25-hydroxyvitamin D (A288AR3C9H)
    Language English
    Publishing date 2008-05-27
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, N.I.H., Intramural ; Research Support, Non-U.S. Gov't ; Review
    ZDB-ID 1074355-8
    ISSN 1873-2585 ; 1047-2797
    ISSN (online) 1873-2585
    ISSN 1047-2797
    DOI 10.1016/j.annepidem.2008.03.010
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