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  1. Article ; Online: Mathematical modelling of cross-linked polyacrylic-based hydrogels: physical properties and drug delivery.

    Bisotti, Filippo / Pizzetti, Fabio / Storti, Giuseppe / Rossi, Filippo

    Drug delivery and translational research

    2022  Volume 12, Issue 8, Page(s) 1928–1942

    Abstract: Recently, hydrogels have gained significant importance in different applications, such as tissue engineering and drug delivery. They are 3D structures of hydrophilic polymers held together through physical or chemical crosslinking. Important is their ... ...

    Abstract Recently, hydrogels have gained significant importance in different applications, such as tissue engineering and drug delivery. They are 3D structures of hydrophilic polymers held together through physical or chemical crosslinking. Important is their ability to swell in presence of solvents, forming elastic gels able to maintain their original shape. Furthermore, these scaffolds slowly degrade in the physiological environment, leading the growing tissue to replace the former filled site. In this work, hydrogels have been synthetized using branched polyacrylic acid (carbomer) cross-linked with an aliphatic polyetherdiamine (elastamine). In particular, we focused on the description of their equilibrium conditions in swollen state and the dynamic simulation of the swelling process. These hydrogels exhibited a peculiar swelling behaviour characterized by an overshoot of the volume increase before reaching the equilibrium. Notably, such behaviour was found at different pH values. In this manuscript, the swelling behaviour was studied by mathematical modelling. Moreover, the ability of these devices to release drugs was also examined through a literature model to understand the different operating transport mechanisms.
    MeSH term(s) Drug Delivery Systems ; Hydrogels/chemistry ; Models, Theoretical ; Polymers/chemistry ; Tissue Engineering
    Chemical Substances Hydrogels ; Polymers
    Language English
    Publishing date 2022-02-12
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2590155-2
    ISSN 2190-3948 ; 2190-393X
    ISSN (online) 2190-3948
    ISSN 2190-393X
    DOI 10.1007/s13346-022-01129-2
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  2. Article: Least-squares estimation of GARCH(1,1) models with heavy-tailed errors

    Preminger, Arie / Storti, Giuseppe

    The econometrics journal Vol. 20, No. 2 , p. 221-258

    2017  Volume 20, Issue 2, Page(s) 221–258

    Author's details Arie Preminger and Giuseppe Storti
    Keywords Asymptotic normality ; Consistency ; GARCH(1,1) ; Heavy tails ; Least-squares estimation ; Two-step estimator
    Language English
    Publisher Wiley-Blackwell
    Publishing place Oxford [u.a.]
    Document type Article
    ZDB-ID 1412265-0 ; 1475536-1
    ISSN 1368-423X ; 1368-4221
    ISSN (online) 1368-423X
    ISSN 1368-4221
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  3. Article: Optimal Design Procedure of Dual-Reflux Pressure Swing Adsorption Units for Nonlinear Separations

    Rossi, Ester / Rota, Renato / Storti, Giuseppe

    Industrial & engineering chemistry process design and development. 2019 Apr. 03, v. 58, no. 16

    2019  

    Abstract: In the frame of dual-reflux pressure swing adsorption processes, design strategies applicable to the complete separation of binary gas mixtures are available only in the case of linear adsorption isotherms. Therefore, in this work we propose a simple and ...

    Abstract In the frame of dual-reflux pressure swing adsorption processes, design strategies applicable to the complete separation of binary gas mixtures are available only in the case of linear adsorption isotherms. Therefore, in this work we propose a simple and efficient design procedure which enables the selection of suitable operating conditions when sharp separation is required and Langmuir adsorption isotherms are involved. Starting from the available strategy for the linear adsorption case, we adapt it to the nonlinear case tuning properly the pressure ratio. Then, the resulting design strategy is validated by application to selected study cases involving different values of key parameters such as different levels of nonlinearity of the isotherms, but also different values of the pressure ratio, feed composition, and selectivity.
    Keywords adsorption ; nonlinear models ; process design ; sorption isotherms ; system optimization
    Language English
    Dates of publication 2019-0403
    Size p. 6644-6652.
    Publishing place American Chemical Society
    Document type Article
    ZDB-ID 1484436-9
    ISSN 1520-5045 ; 0888-5885
    ISSN (online) 1520-5045
    ISSN 0888-5885
    DOI 10.1021/acs.iecr.8b05889
    Database NAL-Catalogue (AGRICOLA)

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  4. Article: Macroporous Polymer⁻Protein Hybrid Materials for Antibody Purification by Combination of Reactive Gelation and Click-Chemistry.

    Lorenz, Marcel / Paganini, Carolina / Storti, Giuseppe / Morbidelli, Massimo

    Materials (Basel, Switzerland)

    2019  Volume 12, Issue 10

    Abstract: Clickable core-shell nanoparticles based on poly(styrene- ...

    Abstract Clickable core-shell nanoparticles based on poly(styrene-
    Language English
    Publishing date 2019-05-14
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2487261-1
    ISSN 1996-1944
    ISSN 1996-1944
    DOI 10.3390/ma12101580
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Model uncertainty and forecast combination in high-dimensional multivariate volatility prediction

    Amendola, Alessandra / Storti, Giuseppe

    Journal of forecasting Vol. 34, No. 2 , p. 83-91

    2015  Volume 34, Issue 2, Page(s) 83–91

    Author's details Alessandra Amendola and Giuseppe Storti
    Keywords forecast combination ; volatility ; multivariate GARCH ; realized covariance matrices ; predictive ability
    Language English
    Publisher Wiley
    Publishing place Chichester
    Document type Article
    ZDB-ID 783432-9 ; 2001645-1
    ISSN 1099-131X ; 0277-6693
    ISSN (online) 1099-131X
    ISSN 0277-6693
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  6. Article ; Online: Recovery of Mineral Oil from Underground Electrical Cables.

    Caimi, Stefano / Colombo, Claudio / Ferrari, Raffaele / Storti, Giuseppe / Morbidelli, Massimo

    International journal of environmental research and public health

    2019  Volume 16, Issue 13

    Abstract: To remove the mineral oil impregnating the insulating paper present in old, disconnected, underground electrical cables, which represents a threat to the environment, two approaches are investigated at laboratory (1 m) and pilot (10 m) scales. The first ... ...

    Abstract To remove the mineral oil impregnating the insulating paper present in old, disconnected, underground electrical cables, which represents a threat to the environment, two approaches are investigated at laboratory (1 m) and pilot (10 m) scales. The first one involves in situ polymerization to clog the inner channel of the cables and to enable the washing of the outer paper region impregnated by the oil by axial flow of a displacing fluid (water). The second approach leaves the inner channel open and employs repeated cycles of pressurization and rest to displace the oil contained in the paper by radially pushing the water from the inner channel into the outer layers. The pressurization and rest times were optimized to obtain the highest oil extraction rate. While the first approach showed limitations in terms of required pressures and operating time, which increase with the length of the cables, the second one was effective at removing 97% of the oil impregnating the paper layers within 25 cycles. Even more relevant, this second solution, in contrast to the first one, can be easily scaled up as it does not depend on the length of the cable, and was successfully tested on a 10 m cable, showing 98% oil recovery.
    MeSH term(s) Electricity ; Energy-Generating Resources ; Environmental Restoration and Remediation ; Mineral Oil ; Polymerization
    Chemical Substances Mineral Oil (8020-83-5)
    Language English
    Publishing date 2019-07-03
    Publishing country Switzerland
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ISSN 1660-4601
    ISSN (online) 1660-4601
    DOI 10.3390/ijerph16132357
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  7. Article ; Online: Current trends in the production of biodegradable bioplastics: The case of polyhydroxyalkanoates.

    Medeiros Garcia Alcântara, João / Distante, Francesco / Storti, Giuseppe / Moscatelli, Davide / Morbidelli, Massimo / Sponchioni, Mattia

    Biotechnology advances

    2020  Volume 42, Page(s) 107582

    Abstract: The global pollution caused by plastics and microplastics is stimulating intense research towards more environmentally friendly materials, preserving the remarkable application characteristics of the currently available polymers. Among these, ... ...

    Abstract The global pollution caused by plastics and microplastics is stimulating intense research towards more environmentally friendly materials, preserving the remarkable application characteristics of the currently available polymers. Among these, polyhydroxyalkanoates (PHAs) have been hailed as the solution to replace conventional, oil-based plastics. Given their biodegradable nature and mechanical properties, their use can be envisioned in a wide range of applications reducing the environmental footprint. Several types of processes have been proposed for their production, which can be grouped in three main classes: (i) microbiological, (ii) enzymatic and (iii) chemical processes. Given the significant amount of literature available on this topic, this review aims to critically analyse what has been proposed so far in each of these classes, with specific reference to their potential to provide bioplastics that can actually replace the currently available materials. A comparison is made, based on the following aspects: achievable molecular structures (such as molecular weight and composition distributions), raw-material and production costs and availability of large-scale production technologies. Finally, some considerations and ideas on what should be further investigated and implemented to realize the economically sustainable production of PHA are brought forward.
    MeSH term(s) Biodegradation, Environmental ; Plastics ; Polyhydroxyalkanoates
    Chemical Substances Plastics ; Polyhydroxyalkanoates
    Language English
    Publishing date 2020-07-02
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Review
    ZDB-ID 47165-3
    ISSN 1873-1899 ; 0734-9750
    ISSN (online) 1873-1899
    ISSN 0734-9750
    DOI 10.1016/j.biotechadv.2020.107582
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  8. Book ; Online: Predictive model of polymer reaction kinetics and coagulation behavior in seeded emulsion co- and ter-polymerizations

    Banetta, Luca / Storti, Giuseppe / Hoogard, George / Simpson, Gareth / Zaccone, Alessio

    2020  

    Abstract: A mathematical model to describe the emulsion polymerization kinetics of co- and ter-polymerizations is developed. The model is based on the classical Smith-Ewart (SE) equations, within the pseudo-homopolymerization approach, with state-of-the-art models ...

    Abstract A mathematical model to describe the emulsion polymerization kinetics of co- and ter-polymerizations is developed. The model is based on the classical Smith-Ewart (SE) equations, within the pseudo-homopolymerization approach, with state-of-the-art models for radical entry and desorption. For co- and ter-polymerizations there are unknown parameters in the model which are related to monomer-specific gel-effect coefficients, that are needed to compute the bimolecular termination reaction rates. The unknown parameters are determined through extensive calibration of the model on literature data for homo- and co-polymerizations of \textit{n}-butyl acrylate (n-BA) and methyl methacrylate (MMA). The so-obtained predictive model is then applied to the modelling of the ter-polymerization of n-BA and MMA with 2-hydroxyethyl methacrylate (2-HEMA) with sodium persulphate (SPR) as initiator: predictions for the time-evolution of particle size and conversion are in excellent agreement with experimental measurements using Dynamic Light Scattering (DLS) and Gas Chromatography (GC), upon tuning the gel-effect coefficient related to 2-HEMA. The developed model is used to quantify the surfactant surface coverage of the particles as well as the total concentration of counterions in the system throughout the entire polymerization process. This key information provides a way to rationalize and control the coagulation behavior during the whole polymerization process.
    Keywords Physics - Chemical Physics ; Condensed Matter - Materials Science ; Condensed Matter - Soft Condensed Matter
    Subject code 660
    Publishing date 2020-07-30
    Publishing country us
    Document type Book ; Online
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  9. Article ; Online: Core-Shell Morphology of Redispersible Powders in Polymer-Cement Waterproof Mortars.

    Caimi, Stefano / Timmerer, Elias / Banfi, Michela / Storti, Giuseppe / Morbidelli, Massimo

    Polymers

    2018  Volume 10, Issue 10

    Abstract: Redispersible powders based on soft core-hard shell polymer particles can be used as additives in polymer-cement mortars. The role of this morphology on the spray-drying production of these powders and on the crack-bridging properties of the ... ...

    Abstract Redispersible powders based on soft core-hard shell polymer particles can be used as additives in polymer-cement mortars. The role of this morphology on the spray-drying production of these powders and on the crack-bridging properties of the corresponding cement-based membranes is investigated. Different polymer latexes at high solid content with varied core-shell ratio, shell thickness and chemical composition (hardness) were prepared from styrene and 2-ethylhexyl acrylate monomers via semi-batch emulsion polymerization. The latexes were characterized in terms of size, composition, and glass transition temperature (
    Language English
    Publishing date 2018-10-10
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2527146-5
    ISSN 2073-4360 ; 2073-4360
    ISSN (online) 2073-4360
    ISSN 2073-4360
    DOI 10.3390/polym10101122
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  10. Article ; Online: Modeling analysis of ultrasonic attenuation and angular scattering measurements of suspended particles.

    Fleckenstein, Peter / Storti, Giuseppe / Deschwanden, Fabian / Gruber, Peter / Lattuada, Marco

    The Journal of the Acoustical Society of America

    2018  Volume 143, Issue 2, Page(s) 1049

    Abstract: A combination of two models previously developed by Faran, and Atkinson and Kytömaa (Faran-AK model) was used to calculate the ultrasonic attenuation and the backscattering signal of a suspension of particles. The model of Atkinson and Kytömaa yielded ... ...

    Abstract A combination of two models previously developed by Faran, and Atkinson and Kytömaa (Faran-AK model) was used to calculate the ultrasonic attenuation and the backscattering signal of a suspension of particles. The model of Atkinson and Kytömaa yielded the viscoelastic contributions while the model of Faran yielded the scattering contribution. A comparison with the more fundamental model by Epstein, Carhart, Allegra, and Hawley validated the combination, where the combination used here proved to be computationally less intensive and more stable. The Faran-AK model outputs were also compared with ultrasound measurements of glass beads with two different particle size distributions and varying concentrations. The comparison showed a very reasonable agreement of model and experiment.
    Language English
    Publishing date 2018-04-06
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 219231-7
    ISSN 1520-8524 ; 0001-4966
    ISSN (online) 1520-8524
    ISSN 0001-4966
    DOI 10.1121/1.5024233
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    Zs.B 591: Show issues Location:
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