LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 10 of total 136

Search options

  1. Book ; Online ; E-Book: Regulating with RNA in bacteria and archaea

    Storz, Gisela / Papenfort, Kai

    2019  

    Author's details edited by Gisela Storz, Kai Papenfort
    Subject code 572.8/8
    Language English
    Size 1 Online-Ressource (xxvii, 593 Seiten), Illustrationen, 29 cm
    Publisher ASM Press
    Publishing place Washington, DC
    Publishing country United States
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    HBZ-ID HT020040048
    ISBN 978-1-68367-024-7 ; 978-0-4296-4695-9 ; 978-0-42964-959-2 ; 978-0-42964-431-3 ; 9781683670230 ; 1-68367-024-8 ; 0-4296-4695-X ; 0-42964-959-2 ; 0-42964-431-0 ; 168367023X
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

    Full text online

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  2. Article: Two for one: regulatory RNAs that encode small proteins.

    Aoyama, Jordan J / Storz, Gisela

    Trends in biochemical sciences

    2023  Volume 48, Issue 12, Page(s) 1035–1043

    Abstract: RNAs are commonly categorized as being either protein-coding mRNAs or noncoding RNAs. However, an increasing number of transcripts, in organisms ranging from bacteria to humans, are being found to have both coding and noncoding functions. In some cases, ... ...

    Abstract RNAs are commonly categorized as being either protein-coding mRNAs or noncoding RNAs. However, an increasing number of transcripts, in organisms ranging from bacteria to humans, are being found to have both coding and noncoding functions. In some cases, the sequences encoding the protein and the regulatory RNA functions are separated, while in other cases the sequences overlap. The protein and RNA can regulate similar or distinct pathways. Here we describe examples illustrating how these dual-function (also denoted bifunctional or dual-component) RNAs are identified and their mechanisms of action and cellular roles. We also discuss the synergy or competition between coding and RNA activity and how these regulators evolved, as well as how more dual-function RNAs might be discovered and exploited.
    MeSH term(s) Humans ; RNA ; RNA, Untranslated ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; Bacteria/metabolism ; RNA, Long Noncoding/genetics
    Chemical Substances RNA (63231-63-0) ; RNA, Untranslated ; RNA, Messenger ; RNA, Long Noncoding
    Language English
    Publishing date 2023-09-28
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 194216-5
    ISSN 1362-4326 ; 0968-0004 ; 0376-5067
    ISSN (online) 1362-4326
    ISSN 0968-0004 ; 0376-5067
    DOI 10.1016/j.tibs.2023.09.002
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 1207: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  3. Book ; Online: ... Bundeswettbewerb "Vorbildliche Strategien kommunaler Suchtprävention" / 2005/2006

    Bretschneider, Michael / Marsen-Storz, Gisela / Rakete, Gerd

    Dokumentation ; Wettbewerb Kommunale Suchtprävention

    2006  

    Institution Deutsches Institut für Urbanistik
    Author's details hrsg. vom Deutschen Institut für Urbanistik (Difu) im Auftr. der Bundeszentrale für Gesundheitliche Aufklärung (BZgA)
    Collection ... Bundeswettbewerb "Vorbildliche Strategien kommunaler Suchtprävention"
    Language German
    Size 1 Online-Ressource (154 Seiten), Diagramme, Karten
    Publishing country Germany
    Document type Book ; Online
    Note Open Access
    HBZ-ID HT021409644
    DOI 10.4126/FRL01-006434560
    Database Repository for Life Sciences

    Full text online

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  4. Article ; Online: New perspectives: Insights into oxidative stress from bacterial studies.

    Storz, Gisela

    Archives of biochemistry and biophysics

    2016  Volume 595, Page(s) 25–27

    Abstract: Studies of the response to hydrogen peroxide as well as the characterization of small, noncoding RNAs and small proteins of less than 50 amino acids in Escherichia coli have given new perspectives on redox sensing, the nature of regulators and gene ... ...

    Abstract Studies of the response to hydrogen peroxide as well as the characterization of small, noncoding RNAs and small proteins of less than 50 amino acids in Escherichia coli have given new perspectives on redox sensing, the nature of regulators and gene organization that are relevant to all organisms.
    MeSH term(s) Bacteria/metabolism ; Bacterial Proteins/metabolism ; Oxidative Stress ; RNA, Bacterial/metabolism
    Chemical Substances Bacterial Proteins ; RNA, Bacterial
    Language English
    Publishing date 2016-04-19
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Intramural
    ZDB-ID 523-x
    ISSN 1096-0384 ; 0003-9861
    ISSN (online) 1096-0384
    ISSN 0003-9861
    DOI 10.1016/j.abb.2015.11.022
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Uc I Zs.237: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  5. Article ; Online: Prevalence of small base-pairing RNAs derived from diverse genomic loci.

    Adams, Philip P / Storz, Gisela

    Biochimica et biophysica acta. Gene regulatory mechanisms

    2020  Volume 1863, Issue 7, Page(s) 194524

    Abstract: Small RNAs (sRNAs) that act by base-pairing have been shown to play important roles in fine-tuning the levels and translation of their target transcripts across a variety of model and pathogenic organisms. Work from many different groups in a wide range ... ...

    Abstract Small RNAs (sRNAs) that act by base-pairing have been shown to play important roles in fine-tuning the levels and translation of their target transcripts across a variety of model and pathogenic organisms. Work from many different groups in a wide range of bacterial species has provided evidence for the importance and complexity of sRNA regulatory networks, which allow bacteria to quickly respond to changes in their environment. However, despite the expansive literature, much remains to be learned about all aspects of sRNA-mediated regulation, particularly in bacteria beyond the well-characterized Escherichia coli and Salmonella enterica species. Here we discuss what is known, and what remains to be learned, about the identification of regulatory base-pairing RNAs produced from diverse genomic loci including how their expression is regulated. This article is part of a Special Issue entitled: RNA and gene control in bacteria edited by Dr. M. Guillier and F. Repoila.
    MeSH term(s) Bacteria/genetics ; Bacteria/metabolism ; Base Pairing ; Gene Expression Regulation, Bacterial ; Genetic Loci ; RNA, Bacterial/genetics ; RNA, Bacterial/metabolism ; RNA, Small Untranslated/genetics ; RNA, Small Untranslated/metabolism
    Chemical Substances RNA, Bacterial ; RNA, Small Untranslated
    Language English
    Publishing date 2020-03-05
    Publishing country Netherlands
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, N.I.H., Intramural ; Review
    ZDB-ID 2918786-2
    ISSN 1876-4320 ; 1874-9399
    ISSN (online) 1876-4320
    ISSN 1874-9399
    DOI 10.1016/j.bbagrm.2020.194524
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 7156: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  6. Article: New perspectives: Insights into oxidative stress from bacterial studies

    Storz, Gisela

    Archives of biochemistry and biophysics. 2016 Apr. 01, v. 595

    2016  

    Abstract: Studies of the response to hydrogen peroxide as well as the characterization of small, noncoding RNAs and small proteins of less than 50 amino acids in Escherichia coli have given new perspectives on redox sensing, the nature of regulators and gene ... ...

    Abstract Studies of the response to hydrogen peroxide as well as the characterization of small, noncoding RNAs and small proteins of less than 50 amino acids in Escherichia coli have given new perspectives on redox sensing, the nature of regulators and gene organization that are relevant to all organisms.
    Keywords Escherichia coli ; amino acids ; hydrogen peroxide ; non-coding RNA ; oxidative stress ; proteins ; regulator genes
    Language English
    Dates of publication 2016-0401
    Size p. 25-27.
    Publishing place Elsevier Inc.
    Document type Article
    ZDB-ID 523-x
    ISSN 1096-0384 ; 0003-9861
    ISSN (online) 1096-0384
    ISSN 0003-9861
    DOI 10.1016/j.abb.2015.11.022
    Database NAL-Catalogue (AGRICOLA)

    Full text online

    More links

    Kategorien

    In stock of ZB MED Bonn / Germany

    Z 4' 70/107: Show issues
    Archiv: Show issues

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  7. Article ; Online: Dual-function Spot 42 RNA encodes a 15-amino acid protein that regulates the CRP transcription factor.

    Aoyama, Jordan J / Raina, Medha / Zhong, Aoshu / Storz, Gisela

    Proceedings of the National Academy of Sciences of the United States of America

    2022  Volume 119, Issue 10, Page(s) e2119866119

    Abstract: SignificanceDual-function RNAs base pair with target messenger RNAs as small regulatory RNAs and encode small protein regulators. However, only a limited number of these dual-function regulators have been identified. In this study, we show that a well- ... ...

    Abstract SignificanceDual-function RNAs base pair with target messenger RNAs as small regulatory RNAs and encode small protein regulators. However, only a limited number of these dual-function regulators have been identified. In this study, we show that a well-characterized base-pairing small RNA surprisingly also encodes a 15-amino acid protein. The very small protein binds the cyclic adenosine monophosphate receptor protein transcription factor to block activation of some promoters, raising the question of how many other transcription factors are modulated by unidentified small proteins.
    MeSH term(s) Amino Acids/chemistry ; Base Pairing ; Escherichia coli/genetics ; Escherichia coli/metabolism ; Escherichia coli Proteins/genetics ; Escherichia coli Proteins/metabolism ; Glucose/metabolism ; Histidine/metabolism ; Operon ; Promoter Regions, Genetic ; Protein Binding ; RNA, Bacterial/genetics ; RNA, Small Untranslated/genetics ; Temperature ; Transcription Factors/metabolism
    Chemical Substances Amino Acids ; Escherichia coli Proteins ; RNA, Bacterial ; RNA, Small Untranslated ; Transcription Factors ; Histidine (4QD397987E) ; Glucose (IY9XDZ35W2)
    Language English
    Publishing date 2022-03-03
    Publishing country United States
    Document type Journal Article
    ZDB-ID 209104-5
    ISSN 1091-6490 ; 0027-8424
    ISSN (online) 1091-6490
    ISSN 0027-8424
    DOI 10.1073/pnas.2119866119
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 1148: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  8. Article ; Online: Small Proteins; Big Questions.

    Gray, Todd / Storz, Gisela / Papenfort, Kai

    Journal of bacteriology

    2021  Volume 204, Issue 1, Page(s) e0034121

    Abstract: In recent years, there has been increased appreciation that a whole category of proteins, small proteins of around 50 amino acids or fewer in length, has been missed by annotation as well as by genetic and biochemical assays. With the increased ... ...

    Abstract In recent years, there has been increased appreciation that a whole category of proteins, small proteins of around 50 amino acids or fewer in length, has been missed by annotation as well as by genetic and biochemical assays. With the increased recognition that small proteins are stable within cells and have regulatory functions, there has been intensified study of these proteins. As a result, important questions about small proteins in bacteria and archaea are coming to the fore. Here, we give an overview of these questions, the initial answers, and the approaches needed to address these questions more fully. More detailed discussions of how small proteins can be identified by ribosome profiling and mass spectrometry approaches are provided by two accompanying reviews (N. Vazquez-Laslop, C. M. Sharma, A. S. Mankin, and A. R. Buskirk, J Bacteriol 204:e00294-21, 2022, https://doi.org/10.1128/JB.00294-21; C. H. Ahrens, J. T. Wade, M. M. Champion, and J. D. Langer, J Bacteriol 204:e00353-21, 2022, https://doi.org/10.1128/JB.00353-21). We are excited by the prospects of new insights and possible therapeutic approaches coming from this emerging field.
    MeSH term(s) Amino Acid Sequence ; Bacteria/genetics ; Bacteria/metabolism ; Bacterial Proteins/chemistry ; Bacterial Proteins/metabolism ; Gene Expression Regulation, Bacterial ; Genome, Bacterial ; Open Reading Frames
    Chemical Substances Bacterial Proteins
    Language English
    Publishing date 2021-07-26
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, N.I.H., Intramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 2968-3
    ISSN 1098-5530 ; 0021-9193
    ISSN (online) 1098-5530
    ISSN 0021-9193
    DOI 10.1128/JB.00341-21
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Ud II Zs.50: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  9. Article ; Online: Synthetic dual-function RNA reveals features necessary for target regulation.

    Aoyama, Jordan J / Raina, Medha / Storz, Gisela

    Journal of bacteriology

    2021  Volume 204, Issue 1, Page(s) JB0034521

    Abstract: Small base pairing RNAs (sRNAs) and small proteins comprise two classes of regulators that allow bacterial cells to adapt to a wide variety of growth conditions. A limited number of transcripts encoding both of these activities, regulation of mRNA ... ...

    Abstract Small base pairing RNAs (sRNAs) and small proteins comprise two classes of regulators that allow bacterial cells to adapt to a wide variety of growth conditions. A limited number of transcripts encoding both of these activities, regulation of mRNA expression by base pairing and synthesis of a small regulatory protein, have been identified. Given that few have been characterized, little is known about the interplay between the two regulatory functions. To investigate the competition between the two activities, we constructed synthetic dual-function RNAs, hereafter referred to as MgtSR or MgtRS, comprised of the
    Language English
    Publishing date 2021-08-30
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2968-3
    ISSN 1098-5530 ; 0021-9193
    ISSN (online) 1098-5530
    ISSN 0021-9193
    DOI 10.1128/JB.00345-21
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Ud II Zs.50: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  10. Article ; Online: σ

    Melamed, Sahar / Zhang, Aixia / Jarnik, Michal / Mills, Joshua / Silverman, Aviezer / Zhang, Hongen / Storz, Gisela

    eLife

    2023  Volume 12

    Abstract: Flagella are important for bacterial motility as well as for pathogenesis. Synthesis of these structures is energy intensive and, while extensive transcriptional regulation has been described, little is known about the posttranscriptional regulation. ... ...

    Abstract Flagella are important for bacterial motility as well as for pathogenesis. Synthesis of these structures is energy intensive and, while extensive transcriptional regulation has been described, little is known about the posttranscriptional regulation. Small RNAs (sRNAs) are widespread posttranscriptional regulators, most base pairing with mRNAs to affect their stability and/or translation. Here, we describe four UTR-derived sRNAs (UhpU, MotR, FliX and FlgO) whose expression is controlled by the flagella sigma factor σ
    MeSH term(s) Escherichia coli Proteins/metabolism ; RNA, Small Untranslated/metabolism ; RNA, Bacterial/metabolism ; Escherichia coli/genetics ; Escherichia coli/metabolism ; Flagella/genetics ; Flagella/metabolism ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; Gene Expression Regulation, Bacterial ; Host Factor 1 Protein/genetics
    Chemical Substances Escherichia coli Proteins ; RNA, Small Untranslated ; RNA, Bacterial ; RNA, Messenger ; Host Factor 1 Protein
    Language English
    Publishing date 2023-10-16
    Publishing country England
    Document type Journal Article ; Research Support, N.I.H., Intramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 2687154-3
    ISSN 2050-084X ; 2050-084X
    ISSN (online) 2050-084X
    ISSN 2050-084X
    DOI 10.7554/eLife.87151
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

To top