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  1. Article ; Online: The trends of mental disorders mortality in China over a 33-year period.

    Luo, Yanan / Wu, Yu / Su, Binbin / Chen, Chen / Zheng, Xiaoying

    Asian journal of psychiatry

    2024  Volume 95, Page(s) 103996

    Abstract: Objectives: We investigated the variations in the trends of mental disorders mortality by age, period, and cohort, over a 33-year period from 1987 to 2020, to reveal the relationship between age, period, cohort, and mental disorders mortality, as well ... ...

    Abstract Objectives: We investigated the variations in the trends of mental disorders mortality by age, period, and cohort, over a 33-year period from 1987 to 2020, to reveal the relationship between age, period, cohort, and mental disorders mortality, as well as providing guidance for resource allocation to prevent mental disorders-related deaths in vulnerable target populations.
    Methods: The data of mental disorders mortality 1987-2020 were from five administrative organizations, which collected from the National Health Commission in China with national monitoring by sex and age, covering 31 provinces in China. The International Classification of Diseases (ICD), its 9th Revision (ICD-9) and its 10th Revision were used to code the mental diseases. From 1987-2002, ICD-9 was used, and ICD-10 was used from 2003 to 2020. The age standardized mortality rates (ASMRs) were calculated using the World Standard Population as the reference. We used joinpoint models to assess the trends of mental disorders mortality in China for the period 1987-2020. And the age-period-cohort models were employed to estimate the age-period-cohort effect on mental disorders mortality.
    Results: The age-standardized overall mental disorders mortality rate (ASMR) showed a downward trend from 1987 to 2020. Further, the ASMR of individuals in urban was higher than that in rural from 1987 to 2001, but, post-2002, this urban-rural disparity in ASMR showed a less clear pattern, with urban areas occasionally surpassing rural areas and vice versa. ASMR is less prevalent among females compared to males overall. The contribution of age effects to mental disorders mortality gradually increases with advancing age, the period effects of mental disorders mortality gradually decrease over time. The cohort effect's contribution to mental disorders mortality decreases in the newly born population, while in the older birth cohorts, the cohort effect's contribution to the mortality rate of mental disorders increases.
    Conclusions: The ASMR exhibits a decreasing trend from 1987 to 2020, and these change trend showed urban-rural and sex differences. The primary factors contributing to this overall decline are period effects and cohort effects. Our results provide valuable information for shaping mental health policies, designing targeted interventions, and preparing for future changes in disease mortality rates. The focus on different demographic factors allows for a nuanced and tailored approach to mental health promotion and intervention strategies.
    MeSH term(s) Humans ; China/epidemiology ; Mental Disorders/mortality ; Mental Disorders/epidemiology ; Male ; Female ; Adult ; Middle Aged ; Young Adult ; Aged ; Adolescent ; Rural Population/statistics & numerical data ; Urban Population/statistics & numerical data ; Urban Population/trends ; Child ; Mortality/trends ; Child, Preschool ; Aged, 80 and over ; Age Factors ; Infant
    Language English
    Publishing date 2024-03-07
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 2456678-0
    ISSN 1876-2026 ; 1876-2018
    ISSN (online) 1876-2026
    ISSN 1876-2018
    DOI 10.1016/j.ajp.2024.103996
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Trends and Patterns of Respiratory Tuberculosis Mortality in Rural and Urban - China, 1987-2021.

    Zhao, Yihao / Su, Binbin / Tian, Yaohua / Shao, Ruitai

    China CDC weekly

    2023  Volume 5, Issue 42, Page(s) 938–942

    Abstract: What is already known about this topic?: In China, an estimated 780,000 individuals contract tuberculosis (TB) every year. With TB ranked as the second most prevalent disease in terms of the morbidity and mortality rates for legally infectious diseases, ...

    Abstract What is already known about this topic?: In China, an estimated 780,000 individuals contract tuberculosis (TB) every year. With TB ranked as the second most prevalent disease in terms of the morbidity and mortality rates for legally infectious diseases, it imparts a substantial disease burden on families and society.
    What is added by this report?: This study identifies specific periods and cohort effects related to trends in respiratory TB mortality in both rural and urban regions of China. The mortality rates have been found to decrease at an annual rate of 5.5% in urban regions and 6.6% in rural ones, with a more marked decline evident in rural areas. These findings represent a significant milestone in the prevention and treatment of respiratory TB in China, especially in its rural locales.
    What are the implications for public health practice?: This research contributes to policymakers' comprehension, assisting in the early formulation of cogent optimization policies, thereby further supporting the United Nations Sustainable Development Goals (SDGs) and the Endeavor to End Respiratory TB Strategy. It is recommended that policymakers prioritize key groups such as children, young adults aged 20-30 in rural areas, and older men (60 years and over) in urban areas when developing these astute optimization policies.
    Language English
    Publishing date 2023-11-03
    Publishing country China
    Document type Journal Article
    ISSN 2096-7071
    ISSN (online) 2096-7071
    DOI 10.46234/ccdcw2023.176
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Epidemiological Shifts in Infectious Diseases in China: Implications and Policy Recommendations.

    Su, Binbin / Talifu, Zuliyaer / Feng, Luzhao

    China CDC weekly

    2023  Volume 5, Issue 42, Page(s) 948–951

    Abstract: In recent decades, China has experienced significant alterations in its landscape of infectious diseases, with noteworthy reductions in historically prevalent illnesses such as tuberculosis and viral hepatitis. At the same time, emerging pathogens like ... ...

    Abstract In recent decades, China has experienced significant alterations in its landscape of infectious diseases, with noteworthy reductions in historically prevalent illnesses such as tuberculosis and viral hepatitis. At the same time, emerging pathogens like severe acute respiratory syndrome (SARS), Influenza A virus subtype H7N9 (H7N9), and SARS coronavirus 2 (SARS-CoV-2) pose new challenges. These epidemiological shifts, fueled by fast economic development, urbanization, modifications in the healthcare system, and an aging population, present considerable obstacles to the country's public health infrastructure and policy frameworks. This article provides a comprehensive review of these changes, underscoring the driving forces behind them and the resultant impact on health policy and infrastructure. It stresses the challenges and calls for an intensification of surveillance efforts, the establishment of collaborative partnerships both nationally and internationally, the encouragement of worldwide cooperation, and the reinforcement of public health education as pivotal strategies for managing China's changing spectrum of infectious diseases.
    Language English
    Publishing date 2023-07-14
    Publishing country China
    Document type Journal Article
    ISSN 2096-7071
    ISSN (online) 2096-7071
    DOI 10.46234/ccdcw2023.178
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Helicobacter pylori infection and small intestinal bacterial overgrowth: a systematic review and meta-analysis.

    Liao, Liang / Su, Bin-Bin / Xu, Shi-Ping

    BMC microbiology

    2023  Volume 23, Issue 1, Page(s) 386

    Abstract: Background: There is a link between Helicobacter pylori (HP) infection and small intestinal bacterial overgrowth (SIBO) with nonspecific digestive symptoms. Nonetheless, whether HP infection is associated with SIBO in adults remains unclear. Based on a ... ...

    Abstract Background: There is a link between Helicobacter pylori (HP) infection and small intestinal bacterial overgrowth (SIBO) with nonspecific digestive symptoms. Nonetheless, whether HP infection is associated with SIBO in adults remains unclear. Based on a meta-analysis, we evaluated this relationship.
    Results: Observational studies relevant to our research were identified by searching PubMed, Embase, the Cochrane Library, and the Web of Science. We evaluated between-study heterogeneity using the Cochrane Q test and estimated the I
    Conclusions: HP infection may be related to SIBO in adults, which supports the detection of SIBO in patients with digestive symptoms and HP infection.
    MeSH term(s) Adult ; Humans ; Middle Aged ; Intestine, Small/microbiology ; Helicobacter pylori ; Helicobacter Infections ; Proton Pump Inhibitors
    Chemical Substances Proton Pump Inhibitors
    Language English
    Publishing date 2023-12-06
    Publishing country England
    Document type Meta-Analysis ; Systematic Review ; Journal Article
    ZDB-ID 2041505-9
    ISSN 1471-2180 ; 1471-2180
    ISSN (online) 1471-2180
    ISSN 1471-2180
    DOI 10.1186/s12866-023-03063-w
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Study and design of amino acid-based radical enzymes using unnatural amino acids.

    Yuan, Feiyan / Su, Binbin / Yu, Yang / Wang, Jiangyun

    RSC chemical biology

    2023  Volume 4, Issue 6, Page(s) 431–446

    Abstract: Radical enzymes harness the power of reactive radical species by placing them in a protein scaffold, and they are capable of catalysing many important reactions. New native radical enzymes, especially those with amino acid-based radicals, in the category ...

    Abstract Radical enzymes harness the power of reactive radical species by placing them in a protein scaffold, and they are capable of catalysing many important reactions. New native radical enzymes, especially those with amino acid-based radicals, in the category of non-heme iron enzymes (including ribonucleotide reductases), heme enzymes, copper enzymes, and FAD-radical enzymes have been discovered and characterized. We discussed recent research efforts to discover new native amino acid-based radical enzymes, and to study the roles of radicals in processes such as enzyme catalysis and electron transfer. Furthermore, design of radical enzymes in a small and simple scaffold not only allows us to study the radical in a well-controlled system and test our understanding of the native enzymes, but also allows us to create powerful enzymes. In the study and design of amino acid-based radical enzymes, the use of unnatural amino acids allows precise control of p
    Language English
    Publishing date 2023-05-18
    Publishing country England
    Document type Journal Article
    ISSN 2633-0679
    ISSN (online) 2633-0679
    DOI 10.1039/d2cb00250g
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: The Impact of Low Fertility Rates on Labor Demand and Socioeconomic Development in China.

    Wu, Yutong / Su, Binbin / Li, Jun

    China CDC weekly

    2023  Volume 5, Issue 27, Page(s) 599–604

    Language English
    Publishing date 2023-07-12
    Publishing country China
    Document type Journal Article
    ISSN 2096-7071
    ISSN (online) 2096-7071
    DOI 10.46234/ccdcw2023.115
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Long-term Trends in Healthy and Unhealthy Life Expectancy Among Adults Aged 60 - A Global Perspective, 1990-2019.

    Su, Binbin / Luo, Yanan / Zhong, Panliang / Zheng, Xiaoying

    China CDC weekly

    2023  Volume 5, Issue 39, Page(s) 877–883

    Abstract: What is already known about this topic?: Traditionally, life expectancy has served as a pivotal measure for assessing population health. However, there is an increasing focus on distinguishing healthy years of life from those characterized by illness, ... ...

    Abstract What is already known about this topic?: Traditionally, life expectancy has served as a pivotal measure for assessing population health. However, there is an increasing focus on distinguishing healthy years of life from those characterized by illness, particularly among the elderly population.
    What is added by this report?: This study conducts an exhaustive global analysis of the trends in healthy and unhealthy life expectancy among adults aged 60 and over from 1990 to 2019. These trends are further correlated with socio-demographic indicators and health services metrics.
    What are the implications for public health practice?: Comprehending the dynamics between healthy and unhealthy life years can equip policymakers with the necessary insights to prioritize interventions. These interventions can thereby secure both quality and longevity of life for the increasingly aging population.
    Language English
    Publishing date 2023-10-10
    Publishing country China
    Document type Journal Article
    ISSN 2096-7071
    ISSN (online) 2096-7071
    DOI 10.46234/ccdcw2023.167
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Transitions in Chronic Disease Mortality in China: Evidence and Implications.

    Su, Binbin / Guo, Shuai / Zheng, Xiaoying

    China CDC weekly

    2023  Volume 5, Issue 50, Page(s) 1131–1134

    Language English
    Publishing date 2023-12-13
    Publishing country China
    Document type Journal Article
    ISSN 2096-7071
    ISSN (online) 2096-7071
    DOI 10.46234/ccdcw2023.211
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Simulating human walking: a model-based reinforcement learning approach with musculoskeletal modeling.

    Su, Binbin / Gutierrez-Farewik, Elena M

    Frontiers in neurorobotics

    2023  Volume 17, Page(s) 1244417

    Abstract: Introduction: Recent advancements in reinforcement learning algorithms have accelerated the development of control models with high-dimensional inputs and outputs that can reproduce human movement. However, the produced motion tends to be less human- ... ...

    Abstract Introduction: Recent advancements in reinforcement learning algorithms have accelerated the development of control models with high-dimensional inputs and outputs that can reproduce human movement. However, the produced motion tends to be less human-like if algorithms do not involve a biomechanical human model that accounts for skeletal and muscle-tendon properties and geometry. In this study, we have integrated a reinforcement learning algorithm and a musculoskeletal model including trunk, pelvis, and leg segments to develop control modes that drive the model to walk.
    Methods: We simulated human walking first without imposing target walking speed, in which the model was allowed to settle on a stable walking speed itself, which was 1.45
    Results: Simulated hip and knee kinematics agreed well with those in experimental observations, but ankle kinematics were less well-predicted.
    Discussion: We finally demonstrated that our reinforcement learning framework also has the potential to model and predict pathological gait that can result from muscle weakness.
    Language English
    Publishing date 2023-10-12
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2453002-5
    ISSN 1662-5218
    ISSN 1662-5218
    DOI 10.3389/fnbot.2023.1244417
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Long-term risk of psychiatric disorder and psychotropic prescription after SARS-CoV-2 infection among UK general population.

    Wang, Yunhe / Su, Binbin / Xie, Junqing / Garcia-Rizo, Clemente / Prieto-Alhambra, Daniel

    Nature human behaviour

    2024  

    Abstract: Despite evidence indicating increased risk of psychiatric issues among COVID-19 survivors, questions persist about long-term mental health outcomes and the protective effect of vaccination. Using UK Biobank data, three cohorts were constructed: SARS-CoV- ... ...

    Abstract Despite evidence indicating increased risk of psychiatric issues among COVID-19 survivors, questions persist about long-term mental health outcomes and the protective effect of vaccination. Using UK Biobank data, three cohorts were constructed: SARS-CoV-2 infection (n = 26,101), contemporary control with no evidence of infection (n = 380,337) and historical control predating the pandemic (n = 390,621). Compared with contemporary controls, infected participants had higher subsequent risks of incident mental health at 1 year (hazard ratio (HR): 1.54, 95% CI 1.42-1.67; P = 1.70 × 10
    Language English
    Publishing date 2024-03-21
    Publishing country England
    Document type Journal Article
    ISSN 2397-3374
    ISSN (online) 2397-3374
    DOI 10.1038/s41562-024-01853-4
    Database MEDical Literature Analysis and Retrieval System OnLINE

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