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  1. Article ; Online: Long-term measurements of ground-level ozone in Windsor, Canada and surrounding areas.

    Zhang, Tianchu / Xu, Xiaohong / Su, Yushan

    Chemosphere

    2022  Volume 294, Page(s) 133636

    Abstract: This study investigated temporal variability of ground-level ozone ( ... ...

    Abstract This study investigated temporal variability of ground-level ozone (O
    MeSH term(s) Air Pollutants/analysis ; Environmental Monitoring ; Ozone/analysis ; Seasons ; Smog/analysis
    Chemical Substances Air Pollutants ; Smog ; Ozone (66H7ZZK23N)
    Language English
    Publishing date 2022-01-22
    Publishing country England
    Document type Journal Article
    ZDB-ID 120089-6
    ISSN 1879-1298 ; 0045-6535 ; 0366-7111
    ISSN (online) 1879-1298
    ISSN 0045-6535 ; 0366-7111
    DOI 10.1016/j.chemosphere.2022.133636
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Long-term measurements of ground-level ozone in Windsor, Canada and surrounding areas

    Zhang, Tianchu / Xu, Xiaohong / Su, Yushan

    Chemosphere. 2022 May, v. 294

    2022  

    Abstract: This study investigated temporal variability of ground-level ozone (O₃) during smog season in Windsor, Canada and surrounding states of the US during 1996–2015. Cluster analysis classified six sites into two groups with similar features of O₃ ... ...

    Abstract This study investigated temporal variability of ground-level ozone (O₃) during smog season in Windsor, Canada and surrounding states of the US during 1996–2015. Cluster analysis classified six sites into two groups with similar features of O₃ concentrations. The first group consists of four urban/suburban sites, Windsor, Allen Park and Lansing in Michigan, and Erie in Ohio, and the second group includes two rural sites, Delaware and National Trail School in Ohio. The similarities among all six sites include (1) diurnal and seasonal variability of O₃ concentrations owing to similar weather conditions, and (2) decreasing peak O₃ (95ᵗʰ percentile) concentrations due to reduced emissions of precursors, thus less photochemical O₃ formation. However, how O₃ levels changed with reduced NOX emissions during the study period and on weekends differed between the two groups. Lower O₃ concentrations were recorded at urban/suburban sites (30 ppb) than at rural sites (34 ppb). At urban sites, annual smog season O₃ concentrations increased by 0.12–3.2 ppb/year. The increasing trends occurred at all percentile levels except for 95ᵗʰ percentile and in most months, due to weakened NO titration effect. At the rural sites, smog-season O₃ concentrations decreased by 0.01–2.71 ppb/year. The decreasing trends were observed at 50-95ᵗʰ percentile levels and in most months. Between the two groups, the urban/suburban group had a greater increment in weekend O₃ concentrations (3.3 vs. 1.6 ppb) due to a greater reduction of local NO emissions on weekend, thus, weakened NO titration effect. Overall, O₃ formation was more sensitive to VOCs during the study period; however, the O₃ formation regime gradually shifted toward more sensitive to NOX during 1996–2007 then became more sensitive to VOCs during 2008–2015. Therefore, controlling anthropogenic VOC emissions is needed to effectively mitigate O₃ pollution in the study region.
    Keywords cluster analysis ; ozone ; photochemistry ; seasonal variation ; smog pollution ; titration ; weather ; Canada ; Delaware ; Michigan ; Ohio
    Language English
    Dates of publication 2022-05
    Publishing place Elsevier Ltd
    Document type Article
    ZDB-ID 120089-6
    ISSN 1879-1298 ; 0045-6535 ; 0366-7111
    ISSN (online) 1879-1298
    ISSN 0045-6535 ; 0366-7111
    DOI 10.1016/j.chemosphere.2022.133636
    Database NAL-Catalogue (AGRICOLA)

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  3. Book ; Online: PruMUX

    Su, Yushan / Murahari, Vishvak / Narasimhan, Karthik / Li, Kai

    Augmenting Data Multiplexing with Model Compression

    2023  

    Abstract: As language models increase in size by the day, methods for efficient inference are critical to leveraging their capabilities for various applications. Prior work has investigated techniques like model pruning, knowledge distillation, and data ... ...

    Abstract As language models increase in size by the day, methods for efficient inference are critical to leveraging their capabilities for various applications. Prior work has investigated techniques like model pruning, knowledge distillation, and data multiplexing to increase model throughput without sacrificing accuracy. In this paper, we combine two such methods -- structured pruning and data multiplexing -- to compound the speedup gains obtained by either method. Our approach, PruMUX, obtains up to 7.5-29.5X throughput improvement over BERT-base model with accuracy threshold from 80% to 74%. We further study various combinations of parameters (such as sparsity and multiplexing factor) in the two techniques to provide a comprehensive analysis of the tradeoff between accuracy and throughput in the resulting models. We then propose Auto-PruMUX, a meta-level model that can predict the high-performance parameters for pruning and multiplexing given a desired accuracy loss budget, providing a practical method to leverage the combination effectively.

    Comment: Findings of the Association for Computational Linguistics (ACL 2023)
    Keywords Computer Science - Machine Learning ; Computer Science - Artificial Intelligence
    Publishing date 2023-05-24
    Publishing country us
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Article: Design and Optimization of a New Anti-reflux Biliary Stent With Retractable Bionic Valve Based on Fluid-Structure Interaction Analysis.

    Su, Yushan / Xiang, Zhongxia / Song, Xiaofei / Zheng, Shuxian / Xu, Xinsheng

    Frontiers in bioengineering and biotechnology

    2022  Volume 10, Page(s) 824207

    Abstract: Duodenal biliary reflux has been a challenging common problem which could cause dreadful complications after biliary stent implantation. A novel anti-reflux biliary stent with a retractable bionic valve was proposed according to the concertina motion ... ...

    Abstract Duodenal biliary reflux has been a challenging common problem which could cause dreadful complications after biliary stent implantation. A novel anti-reflux biliary stent with a retractable bionic valve was proposed according to the concertina motion characteristics of annelids. A 2D equivalent fluid-structure interaction (FSI) model based on the axial section was established to analyze and evaluate the mechanical performances of the anti-reflux biliary stent. Based on this model, four key parameters (initial shear modulus of material, thickness, pitch, and width) were selected to investigate the influence of design parameters on anti-reflux performance via an orthogonal design to optimize the stent. The results of FSI analysis showed that the retrograde closure ratio of the retractable valve primarily depended on initial shear modulus of material (
    Language English
    Publishing date 2022-03-28
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2719493-0
    ISSN 2296-4185
    ISSN 2296-4185
    DOI 10.3389/fbioe.2022.824207
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Book ; Online: Uptake Behavior of Polycyclic Aromatic Compounds during Field Calibrations of the XAD-Based Passive Air Sampler Across Seasons and Locations

    Li, Yuening / Zhan, Faqiang / Su, Yushan / Lei, Ying Duan / Shunthirasingham, Chubashini / Zhou, Zilin / Abbatt, Jonathan P. D. / Hung, Hayley / Wania, Frank

    eISSN:

    2024  

    Abstract: Polycyclic aromatic compounds (PACs) continue to demand attention due to their widespread presence and well-established health implications. Given that incomplete combustion is a major contributor to PACs and inhalation constitutes a crucial human ... ...

    Abstract Polycyclic aromatic compounds (PACs) continue to demand attention due to their widespread presence and well-established health implications. Given that incomplete combustion is a major contributor to PACs and inhalation constitutes a crucial human exposure pathway, a comprehensive understanding of the concentrations, spatial distributions, and fates of a broad range of PACs in the atmosphere is important. Passive air samplers (PASs) are a commonly utilized technique for PAC sampling and monitoring. In this study, we present the results from two 1-year calibration experiments, one starting in summer and the other in winter, using a passive air sampler equipped with XAD resin as the sorbent (XAD-PAS). Throughout both experiments, PACs were consistently sorbed during the initial 6-month period. However, the sorbed amounts for many PACs exhibited a decrease after half a year of deployment. Three hypotheses to explain this phenomenon were explored, including the uptake of atmospheric particles, evaporation from the sorbent, and reactions with photo-oxidants. All had to be rejected based on the obtained data, additional laboratory experiments, and model results. Model simulations were further used to (i) confirm that a loss process must be invoked to explain the observed uptake behavior and (ii) estimate the kinetics of that loss process for different PACs. Sampling rates (SRs) for 28 PACs derived from the linearized uptake curves during the first 6 months of deployment were comparable to those of other semi-volatile organic compounds obtained during the same calibration experiment, and they also demonstrate a consistent negative correlation with volatility.
    Subject code 910
    Language English
    Publishing date 2024-01-29
    Publishing country de
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Book ; Online: Uptake behavior of polycyclic aromatic compounds during field calibrations of the XAD-based passive air sampler across seasons and locations

    Li, Yuening / Zhan, Faqiang / Su, Yushan / Lei, Ying Duan / Shunthirasingham, Chubashini / Zhou, Zilin / Abbatt, Jonathan P. D. / Hung, Hayley / Wania, Frank

    eISSN: 1867-8548

    2024  

    Abstract: Polycyclic aromatic compounds (PACs) continue to demand attention due to their widespread presence and well-established health implications. Given that incomplete combustion is a major contributor to PACs and inhalation constitutes a crucial human ... ...

    Abstract Polycyclic aromatic compounds (PACs) continue to demand attention due to their widespread presence and well-established health implications. Given that incomplete combustion is a major contributor to PACs and inhalation constitutes a crucial human exposure pathway, a comprehensive understanding of the concentrations, spatial distributions, and fates of a broad range of PACs in the atmosphere is important. Passive air samplers (PASs) are a commonly utilized technique for PAC sampling and monitoring. In this study, we present the results from two 1-year calibration experiments, one starting in summer and the other in winter, using a passive air sampler equipped with XAD resin as the sorbent (XAD-PAS). Throughout both experiments, PACs were consistently sorbed during the initial 6-month period. However, the sorbed amounts for many PACs exhibited a decrease after half a year of deployment. Three hypotheses to explain this phenomenon were explored, including the uptake of atmospheric particles, evaporation from the sorbent, and reactions with photo-oxidants. All had to be rejected based on the obtained data, additional laboratory experiments, and model results. Model simulations were further used to (i) confirm that a loss process must be invoked to explain the observed uptake behavior and (ii) estimate the kinetics of that loss process for different PACs. Sampling rates (SRs) for 28 PACs derived from the linearized uptake curves during the first 6 months of deployment were comparable to those of other semi-volatile organic compounds obtained during the same calibration experiment, and they also demonstrate a consistent negative correlation with volatility.
    Subject code 910
    Language English
    Publishing date 2024-01-29
    Publishing country de
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  7. Article ; Online: Design and evaluation of a novel anti-reflux biliary stent with cone spiral valve.

    Wang, Yue / Song, Xiao-Fei / Su, Yu-Shan / Xu, Xin-Sheng

    Proceedings of the Institution of Mechanical Engineers. Part H, Journal of engineering in medicine

    2020  Volume 235, Issue 1, Page(s) 54–64

    Abstract: Endoscopic placement of biliary stent is a well-established palliative treatment for biliary obstruction. However, duodenobiliary reflux after stent placement has been a common problem which may lead to dreadful complications. This paper designed a novel ...

    Abstract Endoscopic placement of biliary stent is a well-established palliative treatment for biliary obstruction. However, duodenobiliary reflux after stent placement has been a common problem which may lead to dreadful complications. This paper designed a novel anti-reflux biliary stent with a cone spiral valve. Fluid-Structure Interaction (FSI) simulations were established to evaluate the efficiency of the anti-reflux stent comparing with a clinically applied standard stent. According to the stress distribution of the valve, the fatigue performance in the stress concentration area was analyzed. The results show that when the antegrade flow through the valve, the cone spiral valve could stretch and open to realize adequate drainage under the normal physiological pressure of biliary tract; When the duodenal reflux through the valve, the valve would be compressed and close with a result of nearly zero at the outlet flow rate. Furthermore, the anti-reflux stent achieved improved radial mechanical performance with 2.7 times higher radial stiffness than standard stent. Finite element analysis (FEA) also indicates that compared with the standard stent, the addition of the anti-reflux valve had little negative effect on flexibility of the stent. Fatigue analysis results showed that the valve was reliable. This research provides the new stent with a cone spiral valve and proves that it is technically feasible and effective for preventing the duodenobiliary reflux while ensuring the antegrade bile flow without compromising the other biomechanical performances.
    MeSH term(s) Biliary Tract ; Cholestasis ; Humans ; Palliative Care ; Stents
    Language English
    Publishing date 2020-09-28
    Publishing country England
    Document type Journal Article
    ZDB-ID 1065942-0
    ISSN 2041-3033 ; 0046-2039 ; 0954-4119
    ISSN (online) 2041-3033
    ISSN 0046-2039 ; 0954-4119
    DOI 10.1177/0954411920959986
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: The decisive role of subordination in social hierarchy in weanling mice and young children.

    Chou, Yu-Ju / Lu, Yi-Han / Ma, Yu-Kai / Su, Yu-Shan / Kuo, Tsung-Han

    iScience

    2021  Volume 24, Issue 2, Page(s) 102073

    Abstract: Social hierarchy plays important roles in maintaining social structures. Despite similarity in concept, frameworks of human hierarchy have seldom been investigated in parallel with other animals. Moreover, the importance of subordination in hierarchical ... ...

    Abstract Social hierarchy plays important roles in maintaining social structures. Despite similarity in concept, frameworks of human hierarchy have seldom been investigated in parallel with other animals. Moreover, the importance of subordination in hierarchical formation has been largely underestimated in previous research. Here we established, compared, and investigated hierarchy in children and weanling mice. Temperament assessments suggested that children who are less persistent, low emotional intensity, and withdrew easily were more likely to be subordinate in competitive scenarios independent of task characteristics and interaction experiences. The tube test further showed that conflicts between mice were not resolved by winner approach but by loser withdrawal, which was mainly determined by intrinsic subordinate status regardless of opponents. Our study presents evolutionary conserved hierarchical relationships in young and a critical role of the intrinsic subordinate characteristics in hierarchical determination. These findings provide a new perspective on social interactions with potential implications for preschool education.
    Language English
    Publishing date 2021-01-19
    Publishing country United States
    Document type Journal Article
    ISSN 2589-0042
    ISSN (online) 2589-0042
    DOI 10.1016/j.isci.2021.102073
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Short-Term Hyperuricemia Leads to Structural Retinal Changes That Can be Reversed by Serum Uric Acid Lowering Agents in Mice.

    Pai, Hung-Liang / Hsieh, Sophie Meng-Tien / Su, Yu-Shan / Sue, Xin-Yuan / Chang, Han-Hsin / Lin, David Pei-Cheng

    Investigative ophthalmology & visual science

    2022  Volume 63, Issue 10, Page(s) 8

    Abstract: Purpose: Metabolic disorders have been implicated in ocular diseases, such as age-related macular degeneration (AMD) and diabetic retinopathy (DR). Recently, hyperuricemia (HUA) has been proposed as another risk factor for AMD, although no cause-and- ... ...

    Abstract Purpose: Metabolic disorders have been implicated in ocular diseases, such as age-related macular degeneration (AMD) and diabetic retinopathy (DR). Recently, hyperuricemia (HUA) has been proposed as another risk factor for AMD, although no cause-and-effect experimental data have been published. In this study, we investigated whether HUA would initiate AMD or related retinal damages in hyperuricemic mice.
    Methods: HUA was induced in male ICR mice by dietary supplements of uric acid and oxonic acid potassium salt, with or without treatments by allopurinol or benzbromarone for various durations. Serum uric acid and angiotensin II concentrations were measured by enzyme-linked immunosorbent assay (ELISA) at regular intervals. The retinal damages were assessed by hematoxylin and eosin staining, immunostaining, and TUNEL assay. The cause-and-effect of HUA was compared among the study groups.
    Results: The results showed that the total thickness of photoreceptor inner and outer segments, as well as the thickness of the photoreceptor outer segment alone, were reduced under HUA. Furthermore, HUA elevated serum angiotensin II, which indicated activation of the renin-angiotensin system (RAS), leading to higher matrix metalloproteinase-2 (MMP-2) expression, and glial activation in the ganglion cell layer. HUA also led to the reduction of retinal pigment epithelium gap junction protein connexin-43 and apoptosis. Uric acid lowering agents, allopurinol or benzbromarone, were effective in ameliorating the impairments.
    Conclusions: HUA may pose as a causative factor of retinal injuries. The reduction of serum uric acid may reduce the detrimental effects caused by HUA.
    MeSH term(s) Allopurinol/pharmacology ; Angiotensin II ; Animals ; Benzbromarone/pharmacology ; Hyperuricemia/drug therapy ; Macular Degeneration/complications ; Male ; Matrix Metalloproteinase 2 ; Mice ; Mice, Inbred ICR ; Uric Acid
    Chemical Substances Angiotensin II (11128-99-7) ; Uric Acid (268B43MJ25) ; Benzbromarone (4POG0RL69O) ; Allopurinol (63CZ7GJN5I) ; Matrix Metalloproteinase 2 (EC 3.4.24.24)
    Language English
    Publishing date 2022-09-13
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 391794-0
    ISSN 1552-5783 ; 0146-0404
    ISSN (online) 1552-5783
    ISSN 0146-0404
    DOI 10.1167/iovs.63.10.8
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Nucleon Transversity Distribution in the Continuum and Physical Mass Limit from Lattice QCD.

    Yao, Fei / Walter, Lisa / Chen, Jiunn-Wei / Hua, Jun / Ji, Xiangdong / Jin, Luchang / Lahrtz, Sebastian / Ma, Lingquan / Mohanta, Protick / Schäfer, Andreas / Shu, Hai-Tao / Su, Yushan / Sun, Peng / Xiong, Xiaonu / Yang, Yi-Bo / Zhang, Jian-Hui

    Physical review letters

    2024  Volume 131, Issue 26, Page(s) 261901

    Abstract: We report a state-of-the-art lattice QCD calculation of the isovector quark transversity distribution of the proton in the continuum and physical mass limit using large-momentum effective theory. The calculation is done at four lattice spacings a={0.098, ... ...

    Abstract We report a state-of-the-art lattice QCD calculation of the isovector quark transversity distribution of the proton in the continuum and physical mass limit using large-momentum effective theory. The calculation is done at four lattice spacings a={0.098,0.085,0.064,0.049}  fm and various pion masses ranging between 220 and 350 MeV, with proton momenta up to 2.8 GeV. The result is nonperturbatively renormalized in the hybrid scheme with self-renormalization, which treats the infrared physics at large correlation distance properly, and extrapolated to the continuum, physical mass, and infinite momentum limit. We also compare with recent global analyses for the nucleon isovector quark transversity distribution.
    Language English
    Publishing date 2024-01-12
    Publishing country United States
    Document type Journal Article
    ZDB-ID 208853-8
    ISSN 1079-7114 ; 0031-9007
    ISSN (online) 1079-7114
    ISSN 0031-9007
    DOI 10.1103/PhysRevLett.131.261901
    Database MEDical Literature Analysis and Retrieval System OnLINE

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