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  1. Article ; Online: Recent advances in understanding and managing asthma [version 1; referees

    Su-Ling Loo / Peter A.B. Wark

    F1000Research, Vol

    2 approved]

    2016  Volume 5

    Abstract: This review highlights the important articles published in the area of asthma research from January 2015 to July 2016. In basic science, significant advances have been made in understanding the link between the innate immune response and type II acquired ...

    Abstract This review highlights the important articles published in the area of asthma research from January 2015 to July 2016. In basic science, significant advances have been made in understanding the link between the innate immune response and type II acquired immune responses in asthma and the role of the airway epithelium. Novel information continues to emerge with regard to the pathogenesis and heterogeneity of severe asthma. There have been important translational clinical trials in the areas of childhood asthma, treatment of allergy to improve asthma outcomes, and improving drug delivery to optimize the management of asthma. In addition, there are increasing data concerning the application of biological agents to the management of severe asthma. This body of work discusses the most notable advances in the understanding and management of asthma.
    Keywords Allergy & Hypersensitivity ; Asthma & Allergic Rhinitis ; Immunity to Infections ; Immunopharmacology & Hematologic Pharmacology ; Innate Immunity ; Integrative Physiology ; Leukocyte Signaling & Gene Expression ; Medical Microbiology ; Respiratory Pediatrics ; Respiratory Pharmacology ; Virology ; Medicine ; R ; Science ; Q
    Subject code 610
    Language English
    Publishing date 2016-08-01T00:00:00Z
    Publisher F1000 Research Ltd
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Article ; Online: IL-25 blockade augments antiviral immunity during respiratory virus infection

    Teresa C. Williams / Su-Ling Loo / Kristy S. Nichol / Andrew T. Reid / Punnam C. Veerati / Camille Esneau / Peter A. B. Wark / Christopher L. Grainge / Darryl A. Knight / Thomas Vincent / Crystal L. Jackson / Kirby Alton / Richard A. Shimkets / Jason L. Girkin / Nathan W. Bartlett

    Communications Biology, Vol 5, Iss 1, Pp 1-

    2022  Volume 13

    Abstract: IL-25 and its receptor are expressed in airway epithelial cells of healthy individuals and patients with asthma and antibody-mediated blockade of IL-25 enhances antiviral immunity and blocks virus-exacerbated asthma responses. ...

    Abstract IL-25 and its receptor are expressed in airway epithelial cells of healthy individuals and patients with asthma and antibody-mediated blockade of IL-25 enhances antiviral immunity and blocks virus-exacerbated asthma responses.
    Keywords Biology (General) ; QH301-705.5
    Language English
    Publishing date 2022-05-01T00:00:00Z
    Publisher Nature Portfolio
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

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    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  3. Article ; Online: Corticosteroid suppression of antiviral immunity increases bacterial loads and mucus production in COPD exacerbations

    Aran Singanayagam / Nicholas Glanville / Jason L. Girkin / Yee Man Ching / Andrea Marcellini / James D. Porter / Marie Toussaint / Ross P. Walton / Lydia J. Finney / Julia Aniscenko / Jie Zhu / Maria-Belen Trujillo-Torralbo / Maria Adelaide Calderazzo / Chris Grainge / Su-Ling Loo / Punnam Chander Veerati / Prabuddha S. Pathinayake / Kristy S. Nichol / Andrew T. Reid /
    Phillip L. James / Roberto Solari / Peter A. B. Wark / Darryl A. Knight / Miriam F. Moffatt / William O. Cookson / Michael R. Edwards / Patrick Mallia / Nathan W. Bartlett / Sebastian L. Johnston

    Nature Communications, Vol 9, Iss 1, Pp 1-

    2018  Volume 16

    Abstract: Corticosteroid therapy is frequently used for chronic obstructive pulmonary disease (COPD) but its use is associated with increased risk of pneumonia. Here the authors show that corticosteroid use impairs innate and adaptive immunity to rhinovirus ... ...

    Abstract Corticosteroid therapy is frequently used for chronic obstructive pulmonary disease (COPD) but its use is associated with increased risk of pneumonia. Here the authors show that corticosteroid use impairs innate and adaptive immunity to rhinovirus infection, which is restored by exogenous IFNβ.
    Keywords Science ; Q
    Language English
    Publishing date 2018-06-01T00:00:00Z
    Publisher Nature Publishing Group
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

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    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  4. Article ; Online: Corticosteroid suppression of antiviral immunity increases bacterial loads and mucus production in COPD exacerbations

    Aran Singanayagam / Nicholas Glanville / Jason L. Girkin / Yee Man Ching / Andrea Marcellini / James D. Porter / Marie Toussaint / Ross P. Walton / Lydia J. Finney / Julia Aniscenko / Jie Zhu / Maria-Belen Trujillo-Torralbo / Maria Adelaide Calderazzo / Chris Grainge / Su-Ling Loo / Punnam Chander Veerati / Prabuddha S. Pathinayake / Kristy S. Nichol / Andrew T. Reid /
    Phillip L. James / Roberto Solari / Peter A. B. Wark / Darryl A. Knight / Miriam F. Moffatt / William O. Cookson / Michael R. Edwards / Patrick Mallia / Nathan W. Bartlett / Sebastian L. Johnston

    Nature Communications, Vol 9, Iss 1, Pp 1-

    2018  Volume 16

    Abstract: Corticosteroid therapy is frequently used for chronic obstructive pulmonary disease (COPD) but its use is associated with increased risk of pneumonia. Here the authors show that corticosteroid use impairs innate and adaptive immunity to rhinovirus ... ...

    Abstract Corticosteroid therapy is frequently used for chronic obstructive pulmonary disease (COPD) but its use is associated with increased risk of pneumonia. Here the authors show that corticosteroid use impairs innate and adaptive immunity to rhinovirus infection, which is restored by exogenous IFNβ.
    Keywords Science ; Q
    Language English
    Publishing date 2018-06-01T00:00:00Z
    Publisher Nature Portfolio
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

    More links

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

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