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  1. AU="Suarez, Eric S"
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  1. Article: Genetic Mutations and Multifactorial Inheritance: Dilated Cardiomyopathy.

    Suarez, Eric S / Knollmann-Ritschel, Barbara E C

    Academic pathology

    2017  Volume 4, Page(s) 2374289517711715

    Abstract: The following fictional case is intended as a learning tool within the Pathology Competencies for Medical Education (PCME), a set of national standards for teaching pathology. These are divided into three basic competencies: Disease Mechanisms and ... ...

    Abstract The following fictional case is intended as a learning tool within the Pathology Competencies for Medical Education (PCME), a set of national standards for teaching pathology. These are divided into three basic competencies: Disease Mechanisms and Processes, Organ System Pathology, and Diagnostic Medicine and Therapeutic Pathology. For additional information, and a full list of learning objectives for all three competencies, see http://journals.sagepub.com/doi/10.1177/2374289517715040.
    Language English
    Publishing date 2017-07-24
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2819382-9
    ISSN 2374-2895
    ISSN 2374-2895
    DOI 10.1177/2374289517711715
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Neuroblastoma, ganglioneuroblastoma, and ganglioneuroma: radiologic-pathologic correlation.

    Lonergan, Gael J / Schwab, Cornelia M / Suarez, Eric S / Carlson, Christian L

    Radiographics : a review publication of the Radiological Society of North America, Inc

    2002  Volume 22, Issue 4, Page(s) 911–934

    Abstract: Neuroblastoma, ganglioneuroblastoma, and ganglioneuroma are tumors of the sympathetic nervous system that arise from primitive sympathogonia and are referred to collectively as neuroblastic tumors. They arise wherever sympathetic tissue exists and may be ...

    Abstract Neuroblastoma, ganglioneuroblastoma, and ganglioneuroma are tumors of the sympathetic nervous system that arise from primitive sympathogonia and are referred to collectively as neuroblastic tumors. They arise wherever sympathetic tissue exists and may be seen in the neck, posterior mediastinum, adrenal gland, retroperitoneum, and pelvis. The three tumors differ in their degree of cellular and extracellular maturation; immature tumors tend to be aggressive and occur in younger patients (median age, just under 2 years), whereas mature tumors occur in older children (median age, approximately 7 years) and tend to behave in a benign fashion. The most benign tumor is the ganglioneuroma, which is composed of gangliocytes and mature stroma. Ganglioneuroblastoma is composed of both mature gangliocytes and immature neuroblasts and has intermediate malignant potential. Neuroblastoma is the most immature, undifferentiated, and malignant tumor of the three. Neuroblastoma, however, may have a relatively benign course, even when metastatic. Thus, these neuroblastic tumors vary widely in their biologic behavior. Features such as DNA content, tumor proto-oncogenes, and catecholamine synthesis influence prognosis, and their presence or absence aids in categorizing patients as high, intermediate, or low risk. Treatment consists of surgery and, usually, chemotherapy. Despite recent advances in treatment, including bone marrow transplantation, neuroblastoma remains a relatively lethal tumor, accounting for 10% of pediatric cancers but 15% of cancer deaths in children.
    MeSH term(s) Ganglioneuroblastoma/diagnostic imaging ; Ganglioneuroblastoma/pathology ; Ganglioneuroma/diagnostic imaging ; Ganglioneuroma/pathology ; Humans ; Magnetic Resonance Imaging ; Neoplasm Staging ; Neuroblastoma/diagnostic imaging ; Neuroblastoma/pathology ; Prognosis ; Risk Factors ; Tomography, X-Ray Computed
    Language English
    Publishing date 2002-07
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 603172-9
    ISSN 1527-1323 ; 0271-5333
    ISSN (online) 1527-1323
    ISSN 0271-5333
    DOI 10.1148/radiographics.22.4.g02jl15911
    Database MEDical Literature Analysis and Retrieval System OnLINE

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