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  1. AU="Subramanian, Harshith"
  2. AU="Hasib, Al"
  3. AU="Gao, Hongyang"
  4. AU="Bedrosian, P. A."
  5. AU="Hotujac, Ljubomir"
  6. AU="Falato, C"
  7. AU="Mayrink, Marcelo Oliveira"
  8. AU="Davidoff, Dahlia F"
  9. AU=Endo A
  10. AU="Chunlei Yu"
  11. AU="Nagao, Asuteka"
  12. AU="Derwael, Céline" AU="Derwael, Céline"
  13. AU="Yao, Yang"
  14. AU=Strutz Frank
  15. AU="Won-Sang Lee"
  16. AU="the ICHseq Investigators" AU="the ICHseq Investigators"
  17. AU="Green, J G"
  18. AU="Xinguang Yang"
  19. AU="Masamed, Rinat"
  20. AU="Flores-Estrada, Diana"
  21. AU="Castellanos, Jason A"
  22. AU="Kiberd, Bryce A"
  23. AU="Kaushal, Deepak"
  24. AU="Rouzaire, Paul"
  25. AU="Mohammed A. S. Abourehab"
  26. AU="Basa, S."
  27. AU="Rohner, Eliane"
  28. AU="Abu-Mahfouz, Adnan M"
  29. AU="Falanti, Andrea"
  30. AU="Yujing Dang"
  31. AU="Clare Duncan"
  32. AU="Calvo Soto, Andrea Patricia"
  33. AU="Joanna I. Olszewska"
  34. AU="Francesco Cavallieri"
  35. AU="Betaieb, Ehssen"
  36. AU="Fan, Xiaoyu"
  37. AU="Riveros-Magaña, Alma Rocío"
  38. AU="Zhang, Wei-Fen"
  39. AU="Ciuca, Catrinel"
  40. AU="Friend, James R"
  41. AU="Colin R. Jackson"
  42. AU="Messina, Claudia"
  43. AU="Faircloth, Chelsey"
  44. AU="Md. Zabirul Islam" AU="Md. Zabirul Islam"
  45. AU="Butcher, Xochitl"
  46. AU="Espay, Alberto J."

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  1. Artikel ; Online: Rodent Gymnastics: Neurobehavioral Assays in Ischemic Stroke.

    Nampoothiri, Sreekala S / Potluri, Tanvi / Subramanian, Harshith / Krishnamurthy, Rajanikant G

    Molecular neurobiology

    2016  Band 54, Heft 9, Seite(n) 6750–6761

    Abstract: Despite years of research, most preclinical trials on ischemic stroke have remained unsuccessful owing to poor methodological and statistical standards leading to "translational roadblocks." Various behavioral tests have been established to evaluate ... ...

    Abstract Despite years of research, most preclinical trials on ischemic stroke have remained unsuccessful owing to poor methodological and statistical standards leading to "translational roadblocks." Various behavioral tests have been established to evaluate traits such as sensorimotor function, cognitive and social interactions, and anxiety-like and depression-like behavior. A test's validity is of cardinal importance as it influences the chance of a successful translation of preclinical results to clinical settings. The mission of choosing a behavioral test for a particular project is, therefore, imperative and the present review aims to provide a structured way to evaluate rodent behavioral tests with implications in ischemic stroke.
    Mesh-Begriff(e) Animals ; Brain Ischemia/diagnosis ; Brain Ischemia/psychology ; Exploratory Behavior/physiology ; Hand Strength/physiology ; Mice ; Motor Activity/physiology ; Rats ; Rotarod Performance Test/methods ; Rotarod Performance Test/psychology ; Stroke/diagnosis ; Stroke/psychology
    Sprache Englisch
    Erscheinungsdatum 2016-10-17
    Erscheinungsland United States
    Dokumenttyp Journal Article ; Review
    ZDB-ID 645020-9
    ISSN 1559-1182 ; 0893-7648
    ISSN (online) 1559-1182
    ISSN 0893-7648
    DOI 10.1007/s12035-016-0195-6
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  2. Artikel ; Online: Development of a genetic toolset for the highly engineerable and metabolically versatile Acinetobacter baylyi ADP1.

    Biggs, Bradley W / Bedore, Stacy R / Arvay, Erika / Huang, Shu / Subramanian, Harshith / McIntyre, Emily A / Duscent-Maitland, Chantel V / Neidle, Ellen L / Tyo, Keith E J

    Nucleic acids research

    2020  Band 48, Heft 9, Seite(n) 5169–5182

    Abstract: One primary objective of synthetic biology is to improve the sustainability of chemical manufacturing. Naturally occurring biological systems can utilize a variety of carbon sources, including waste streams that pose challenges to traditional chemical ... ...

    Abstract One primary objective of synthetic biology is to improve the sustainability of chemical manufacturing. Naturally occurring biological systems can utilize a variety of carbon sources, including waste streams that pose challenges to traditional chemical processing, such as lignin biomass, providing opportunity for remediation and valorization of these materials. Success, however, depends on identifying micro-organisms that are both metabolically versatile and engineerable. Identifying organisms with this combination of traits has been a historic hindrance. Here, we leverage the facile genetics of the metabolically versatile bacterium Acinetobacter baylyi ADP1 to create easy and rapid molecular cloning workflows, including a Cas9-based single-step marker-less and scar-less genomic integration method. In addition, we create a promoter library, ribosomal binding site (RBS) variants and test an unprecedented number of rationally integrated bacterial chromosomal protein expression sites and variants. At last, we demonstrate the utility of these tools by examining ADP1's catabolic repression regulation, creating a strain with improved potential for lignin bioprocessing. Taken together, this work highlights ADP1 as an ideal host for a variety of sustainability and synthetic biology applications.
    Mesh-Begriff(e) Acinetobacter/genetics ; Acinetobacter/metabolism ; Cloning, Molecular/methods ; Genome, Bacterial ; Genomics ; Lignin/metabolism ; Metabolic Engineering ; Promoter Regions, Genetic ; Ribosomes/metabolism
    Chemische Substanzen Lignin (9005-53-2)
    Sprache Englisch
    Erscheinungsdatum 2020-05-04
    Erscheinungsland England
    Dokumenttyp Journal Article ; Research Support, N.I.H., Extramural ; Research Support, U.S. Gov't, Non-P.H.S.
    ZDB-ID 186809-3
    ISSN 1362-4962 ; 1362-4954 ; 0301-5610 ; 0305-1048
    ISSN (online) 1362-4962 ; 1362-4954
    ISSN 0301-5610 ; 0305-1048
    DOI 10.1093/nar/gkaa167
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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    Verfügbar in ZB MED Köln/Königswinter

    Zs.A 1067: Hefte anzeigen Standort:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
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    Über subito bestellen

    Dieser Service ist kostenpflichtig (siehe Lieferbedingungen von subito). Bestellungen, die einen Artikel nebst Supplementary Material umfassen, werden grundsätzlich wie mehrfache Bestellungen bearbeitet. Gebühren fallen in diesen Fällen für jede einzelne Bestellung an.

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