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  1. Article ; Online: Closure of Gastrocutaneous Fistula Following Bariatric Surgery: a Systematic Review.

    Bawa, Jasmine H / Sulutaura, Liene / Patel, Nikhil M / Sufi, Pratik A / Parmar, Chetan

    Obesity surgery

    2023  Volume 33, Issue 11, Page(s) 3658–3668

    Abstract: Gastrocutaneous fistula (GCF) is a devastating complication that can arise after bariatric and metabolic surgery (BMS). This systematic review examines the success rate of closure techniques of GCF. A systematic search was conducted across MEDLINE, ... ...

    Abstract Gastrocutaneous fistula (GCF) is a devastating complication that can arise after bariatric and metabolic surgery (BMS). This systematic review examines the success rate of closure techniques of GCF. A systematic search was conducted across MEDLINE, Embase and Cochrane databases to identify studies which reported on closure techniques of GCF after BMS in adults. Thirty-three studies (n = 108 patients) were included. Seventeen different techniques were used to close GCF across all studies. The most popular were stents (n = 17), tissue sealants (n = 12) and over-the-scope clips (n = 11). Twenty-one studies used multiple techniques to attempt closure, including endoscopic vacuum therapy and revisional surgery. This systematic review demonstrates current practice focusing on endoscopic methods such as stents and over-the-scope clips, with relative success in closing GCF.
    MeSH term(s) Adult ; Humans ; Gastrostomy/adverse effects ; Cutaneous Fistula/surgery ; Cutaneous Fistula/complications ; Obesity, Morbid/surgery ; Gastric Fistula/etiology ; Gastric Fistula/surgery ; Bariatric Surgery/adverse effects
    Language English
    Publishing date 2023-10-07
    Publishing country United States
    Document type Systematic Review ; Journal Article ; Review
    ZDB-ID 1070827-3
    ISSN 1708-0428 ; 0960-8923
    ISSN (online) 1708-0428
    ISSN 0960-8923
    DOI 10.1007/s11695-023-06861-3
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    Zs.A 3381: Show issues Location:
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  2. Article ; Online: Conservative Managing of Bezoar in Giant Hiatus Hernia Causing Gastric Outlet Obstruction During the COVID-19 Pandemic.

    Khalil, Hany / Parmar, Chetan / Sufi, Pratik

    Obesity surgery

    2021  Volume 31, Issue 6, Page(s) 2780–2782

    MeSH term(s) Bezoars/complications ; Bezoars/surgery ; COVID-19 ; Gastric Outlet Obstruction/etiology ; Gastric Outlet Obstruction/surgery ; Hernia, Hiatal/epidemiology ; Humans ; Obesity, Morbid/surgery ; Pandemics ; SARS-CoV-2
    Language English
    Publishing date 2021-02-12
    Publishing country United States
    Document type Letter
    ZDB-ID 1070827-3
    ISSN 1708-0428 ; 0960-8923
    ISSN (online) 1708-0428
    ISSN 0960-8923
    DOI 10.1007/s11695-021-05250-y
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    Zs.A 3381: Show issues Location:
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  3. Article ; Online: First Report Globally of Bariatric and Metabolic Surgery in Patients Who Have Blindness or Significant Visual Impairment: Lessons Learnt and Recommendations.

    Parmar, Chetan D / Bosch, Karen / Lacea, Emilane / Sufi, Pratik / Dacre, Jane / Burton, Katarina

    Obesity surgery

    2023  Volume 33, Issue 4, Page(s) 1289–1291

    MeSH term(s) Humans ; Obesity, Morbid/surgery ; Bariatric Surgery ; Gastric Bypass ; Blindness/etiology ; Blindness/surgery ; Bariatrics ; Gastrectomy ; Treatment Outcome ; Laparoscopy ; Retrospective Studies
    Language English
    Publishing date 2023-02-04
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1070827-3
    ISSN 1708-0428 ; 0960-8923
    ISSN (online) 1708-0428
    ISSN 0960-8923
    DOI 10.1007/s11695-023-06487-5
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  4. Article ; Online: E-cigarette, Obesity and Bariatric Surgery: Guidelines for the Bariatric Societies.

    Parmar, Chetan D / Lee, Lyndcie / Sufi, Pratik

    Obesity surgery

    2019  Volume 29, Issue 9, Page(s) 2982–2984

    Language English
    Publishing date 2019-07-09
    Publishing country United States
    Document type Letter
    ZDB-ID 1070827-3
    ISSN 1708-0428 ; 0960-8923
    ISSN (online) 1708-0428
    ISSN 0960-8923
    DOI 10.1007/s11695-019-04017-w
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  5. Article ; Online: Bariatric Surgery as a Bridge to Facilitate Renal Transplantation in Patients with End-Stage Renal Disease.

    Bosch, Karen D / Harrington, Cuan / Sulutaura, Liene / Lacea, Emilane / Burton, Katarina / Fernandez-Munoz, Naiara / Dugal, Neal / Sufi, Pratik / Al Midani, Ammar / Parmar, Chetan

    Obesity surgery

    2024  Volume 34, Issue 2, Page(s) 355–362

    Abstract: Purpose: Renal transplantation (RT) is not recommended above BMI 40 kg/m: Methods: We reviewed data from 31 patients with RF referred for BS between 2013 and 2021. We compared the outcomes of patients with RF who underwent BS to those who were ... ...

    Abstract Purpose: Renal transplantation (RT) is not recommended above BMI 40 kg/m
    Methods: We reviewed data from 31 patients with RF referred for BS between 2013 and 2021. We compared the outcomes of patients with RF who underwent BS to those who were referred but did not undergo BS. Controls matched for age/BMI/comorbidity (MC) but without RF were used for comparison.
    Results: Of 31 patients referred, 19 proceeded with BS (68% female, median age 52 years, BMI 46.2 ± 4.9 kg/m
    Conclusion: BS in patients with RF increased access to RT and was safe and effective. We therefore recommend consideration of BS in patients with obesity and RF in specialised units.
    MeSH term(s) Humans ; Female ; Middle Aged ; Male ; Obesity, Morbid/surgery ; Kidney Transplantation ; Bariatric Surgery/methods ; Obesity/complications ; Kidney Failure, Chronic/surgery ; Kidney Failure, Chronic/complications ; Retrospective Studies ; Treatment Outcome
    Language English
    Publishing date 2024-01-04
    Publishing country United States
    Document type Review ; Journal Article
    ZDB-ID 1070827-3
    ISSN 1708-0428 ; 0960-8923
    ISSN (online) 1708-0428
    ISSN 0960-8923
    DOI 10.1007/s11695-023-06985-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Depot- and diabetes-specific differences in norepinephrine-mediated adipose tissue angiogenesis, vascular tone, collagen deposition and morphology in obesity.

    Shen, Lei / Dashwood, Michael R / Casale, Carlo / Orie, Nelson N / Evans, Ian M / Sufi, Pratik / Gray, Rosaire / Mohamed-Ali, Vidya

    Life sciences

    2022  Volume 305, Page(s) 120756

    Abstract: Aims: Norepinephrine (NE) is a known regulator of adipose tissue (AT) metabolism, angiogenesis, vasoconstriction and fibrosis. This may be through autocrine/paracrine effects on local resistance vessel function and morphology. The aims of this study ... ...

    Abstract Aims: Norepinephrine (NE) is a known regulator of adipose tissue (AT) metabolism, angiogenesis, vasoconstriction and fibrosis. This may be through autocrine/paracrine effects on local resistance vessel function and morphology. The aims of this study were to investigate, in human subcutaneous and omental adipose tissue (SAT and OAT): NE synthesis, angiogenesis, NE-mediated arteriolar vasoconstriction, the induction of collagen gene expression and its deposition in non-diabetic versus diabetic obese subjects.
    Materials and methods: SAT and OAT from obese patients were used to investigate tissue NE content, tyrosine hydroxylase (TH) density, angiogenesis including capillary density, angiogenic capacity and angiogenic gene expression, NE-mediated arteriolar vasoconstriction and collagen deposition.
    Key findings: In the non-diabetic group, NE concentration, TH immunoreactivity, angiogenesis and maximal vasoconstriction were significantly higher in OAT compared to SAT (p < 0.05). However, arterioles from OAT showed lower NE sensitivity compared to SAT (10
    Significance: SAT depot in non-diabetic obese patients exhibited relatively low NE synthesis, angiogenesis, tissue fibrosis and high vasoreactivity, due to preserved NE sensitivity. The local NE synthesis in OAT and diabetes desensitizes NE-induced vasoconstriction, and may also explain the greater tissue angiogenesis and fibrosis in these depots.
    MeSH term(s) Adipose Tissue/metabolism ; Collagen/metabolism ; Diabetes Mellitus/metabolism ; Fibrosis ; Humans ; Neovascularization, Pathologic/metabolism ; Norepinephrine/metabolism ; Obesity/metabolism
    Chemical Substances Collagen (9007-34-5) ; Norepinephrine (X4W3ENH1CV)
    Language English
    Publishing date 2022-06-30
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 3378-9
    ISSN 1879-0631 ; 0024-3205
    ISSN (online) 1879-0631
    ISSN 0024-3205
    DOI 10.1016/j.lfs.2022.120756
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  7. Article: Depot- and diabetes-specific differences in norepinephrine-mediated adipose tissue angiogenesis, vascular tone, collagen deposition and morphology in obesity

    Shen, Lei / Dashwood, Michael R. / Casale, Carlo / Orie, Nelson N. / Evans, Ian M. / Sufi, Pratik / Gray, Rosaire / Mohamed-Ali, Vidya

    Life sciences. 2022 Sept. 15, v. 305

    2022  

    Abstract: Norepinephrine (NE) is a known regulator of adipose tissue (AT) metabolism, angiogenesis, vasoconstriction and fibrosis. This may be through autocrine/paracrine effects on local resistance vessel function and morphology. The aims of this study were to ... ...

    Abstract Norepinephrine (NE) is a known regulator of adipose tissue (AT) metabolism, angiogenesis, vasoconstriction and fibrosis. This may be through autocrine/paracrine effects on local resistance vessel function and morphology. The aims of this study were to investigate, in human subcutaneous and omental adipose tissue (SAT and OAT): NE synthesis, angiogenesis, NE-mediated arteriolar vasoconstriction, the induction of collagen gene expression and its deposition in non-diabetic versus diabetic obese subjects. SAT and OAT from obese patients were used to investigate tissue NE content, tyrosine hydroxylase (TH) density, angiogenesis including capillary density, angiogenic capacity and angiogenic gene expression, NE-mediated arteriolar vasoconstriction and collagen deposition. In the non-diabetic group, NE concentration, TH immunoreactivity, angiogenesis and maximal vasoconstriction were significantly higher in OAT compared to SAT (p < 0.05). However, arterioles from OAT showed lower NE sensitivity compared to SAT (10⁻⁸ M to 10–⁷.⁵ M, p < 0.05). A depot-specific difference in collagen deposition was also observed, being greater in OAT than SAT. In the diabetic group, no significant depot-specific differences were seen in NE synthesis, angiogenesis, vasoconstriction or collagen deposition. SAT arterioles showed significantly lower sensitivity to NE (10⁻⁸ M to 10–⁷.⁵ M, p < 0.05) compared to the non-diabetic group. SAT depot in non-diabetic obese patients exhibited relatively low NE synthesis, angiogenesis, tissue fibrosis and high vasoreactivity, due to preserved NE sensitivity. The local NE synthesis in OAT and diabetes desensitizes NE-induced vasoconstriction, and may also explain the greater tissue angiogenesis and fibrosis in these depots.
    Keywords adipose tissue ; angiogenesis ; autocrine signaling ; collagen ; diabetes ; fibrosis ; gene expression ; humans ; immune response ; metabolism ; norepinephrine ; obesity ; tyrosine 3-monooxygenase ; vasoconstriction
    Language English
    Dates of publication 2022-0915
    Publishing place Elsevier Inc.
    Document type Article
    ZDB-ID 3378-9
    ISSN 1879-0631 ; 0024-3205
    ISSN (online) 1879-0631
    ISSN 0024-3205
    DOI 10.1016/j.lfs.2022.120756
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  8. Article ; Online: Reply to "Bleeding in Sleeve Gastrectomy-A Simple and Cost-Effective Solution".

    Mukherjee, Samrat / Alhamdani, Ali / Sufi, Pratik / Parmar, Chetan

    Obesity surgery

    2017  Volume 27, Issue 3, Page(s) 814–815

    Language English
    Publishing date 2017-03
    Publishing country United States
    Document type Letter
    ZDB-ID 1070827-3
    ISSN 1708-0428 ; 0960-8923
    ISSN (online) 1708-0428
    ISSN 0960-8923
    DOI 10.1007/s11695-016-2507-3
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  9. Article ; Online: Gastro-Colic Fistula After Sleeve Gastrectomy Leak: Our Experience with this Rare Complication.

    Parmar, Chetan D / Khalil, Hany / Lakdawala, Muffazal / Bhan, Chetan / Sufi, Pratik

    Obesity surgery

    2019  Volume 29, Issue 11, Page(s) 3771–3772

    Abstract: Background: Sleeve gastrectomy (SG) is one of the commonest bariatric procedure performed worldwide (Asian Journal of Endoscopic Surgery 7:314-6, 2014). Leaks reported in 1 to 7% of cases are difficult to manage after SG. Leaks can be graded into acute ( ...

    Abstract Background: Sleeve gastrectomy (SG) is one of the commonest bariatric procedure performed worldwide (Asian Journal of Endoscopic Surgery 7:314-6, 2014). Leaks reported in 1 to 7% of cases are difficult to manage after SG. Leaks can be graded into acute (within 7 days), early (within 1-6 weeks), late (after 6 weeks) and chronic (after 12 weeks) (Asian Journal of Endoscopic Surgery 7:314-6, 2014). Oesophageal stents can be used for acute leaks. Gastro-colic fistula (GCF) is a rare complication following a chronic leak after SG (Asian Journal of Endoscopic Surgery 7:314-6, 2014). We would like to share our experience of a rare and challenging case of GCF after SG leak.
    Method: Prospectively collected data in our tertiary bariatric centre was retrieved.
    Results: A 31-year-old female with body mass index (BMI) of 46.2 kg/m
    Conclusion: SG leaks can add long-term morbidity. Stent can be used successfully to treat SG leak if used judiciously. There should be low threshold for investigating patients with EWL of > 100% for anatomical complications like stricture, fistula or kink in the gastric sleeve. We wanted to make the bariatric fraternity aware of a rare late (> 12 weeks) complication of gastro-colic fistula after successfully treated SG leak. Limited literature is published about this rare complication and its management which ranges from conservative management to stent placement to surgical intervention (Asian Journal of Endoscopic Surgery 7:314-6, 2014; Clinical Case Reports 6:1342-1346, 2008; Surgery for Obesity and Related Diseases 6:308-12, 2010). It can be dealt with successfully with minimally invasive technique by a multidisciplinary team in an experienced tertiary bariatric unit.
    MeSH term(s) Adult ; Anastomotic Leak ; Colon/physiopathology ; Colon/surgery ; Endoscopy, Digestive System ; Female ; Gastrectomy/adverse effects ; Gastric Fistula ; Humans ; Obesity, Morbid/surgery ; Stents ; Stomach/physiopathology ; Stomach/surgery
    Language English
    Publishing date 2019-07-11
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 1070827-3
    ISSN 1708-0428 ; 0960-8923
    ISSN (online) 1708-0428
    ISSN 0960-8923
    DOI 10.1007/s11695-019-04086-x
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  10. Article ; Online: Primary Banded Sleeve Gastrectomy: a Systematic Review.

    Parmar, Chetan D / Efeotor, O / Ali, A / Sufi, Pratik / Mahawar, K K

    Obesity surgery

    2018  Volume 29, Issue 2, Page(s) 698–704

    Abstract: We aim to investigate any advantages of primary banded sleeve gastrectomy (BSG) over laparoscopic sleeve gastrectomy (LSG). A literature search was performed according to the PRISMA guidelines. There were 236 patients with the mean age of 45.4 years, BMI ...

    Abstract We aim to investigate any advantages of primary banded sleeve gastrectomy (BSG) over laparoscopic sleeve gastrectomy (LSG). A literature search was performed according to the PRISMA guidelines. There were 236 patients with the mean age of 45.4 years, BMI of 47.9 kg/m
    MeSH term(s) Gastrectomy/methods ; Humans ; Laparoscopy ; Obesity, Morbid/surgery ; Postoperative Complications ; Reoperation/statistics & numerical data ; Weight Loss
    Language English
    Publishing date 2018-12-14
    Publishing country United States
    Document type Comparative Study ; Journal Article ; Systematic Review
    ZDB-ID 1070827-3
    ISSN 1708-0428 ; 0960-8923
    ISSN (online) 1708-0428
    ISSN 0960-8923
    DOI 10.1007/s11695-018-03626-1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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