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  1. Article ; Online: Diffuse large B-cell lymphoma with composite germinal center and non-germinal center types: A report of two cases.

    Sugitani, Ayumi / Fukuhara, Suguru / Shibata, Maki / Ichihara, Ryosuke / Furukawa, Haruhi / Maeshima, Akiko Miyagi

    Journal of clinical and experimental hematopathology : JCEH

    2023  Volume 63, Issue 3, Page(s) 181–186

    Abstract: We report two cases of diffuse large B-cell lymphoma (DLBCL) with composite germinal center B-cell (GCB) and non-GCB types. Case 1 was a 72-year-old woman with inguinal lymph node swelling. Two morphologically different lesions were concurrently observed ...

    Abstract We report two cases of diffuse large B-cell lymphoma (DLBCL) with composite germinal center B-cell (GCB) and non-GCB types. Case 1 was a 72-year-old woman with inguinal lymph node swelling. Two morphologically different lesions were concurrently observed in needle biopsy specimens. One lesion was DLBCL with centroblastic morphology and a GCB phenotype (CD10
    MeSH term(s) Male ; Female ; Humans ; Aged ; Adult ; Neoplasm Recurrence, Local/pathology ; Lymphoma, Large B-Cell, Diffuse/pathology ; B-Lymphocytes/pathology ; Germinal Center/metabolism ; Germinal Center/pathology ; Biopsy, Needle ; Prognosis
    Language English
    Publishing date 2023-07-28
    Publishing country Japan
    Document type Case Reports ; Journal Article
    ZDB-ID 2395568-5
    ISSN 1880-9952 ; 1880-9952
    ISSN (online) 1880-9952
    ISSN 1880-9952
    DOI 10.3960/jslrt.23020
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Ovarian Mesonephric-Like Adenocarcinoma With Recurrent Liver Metastases: A Case Report with Analysis of Therapeutic Molecular Targets.

    Sugitani, Ayumi / Ogawa, Ayako / Yoshida, Hiroshi / Kobayashi-Kato, Mayumi / Kikkawa, Nao / Tanase, Yasuhito / Uno, Masaya / Ishikawa, Mitsuya / Kato, Tomoyasu

    International journal of surgical pathology

    2023  Volume 32, Issue 3, Page(s) 578–585

    Abstract: Ovarian mesonephric-like adenocarcinoma (MLA) is a rare cancer subtype. We describe a patient with ovarian MLA wherein liver metastases developed 1 month after surgery. A phenotypic analysis of the tumor was performed to identify molecular therapeutic ... ...

    Abstract Ovarian mesonephric-like adenocarcinoma (MLA) is a rare cancer subtype. We describe a patient with ovarian MLA wherein liver metastases developed 1 month after surgery. A phenotypic analysis of the tumor was performed to identify molecular therapeutic targets. A 53-year-old woman, without any symptoms, underwent uterine cancer screening. Transvaginal ultrasonography revealed an ovarian mass, and subsequent pelvic magnetic resonance imaging showed a 13 × 10 cm multicystic ovarian lesion with a solid part. No extra ovarian lesions were observed and a staging laparotomy was performed. Pathological examination revealed an MLA of the left ovary (stage IC1). The tumor comprised tumor cells in a tubular pattern with intraluminal eosinophilic material, as well as mixed glandular and papillary, cord-like, and solid patterns. Endometriosis was also observed. Immunohistochemically, the tumor cells were positive for PAX8, GATA3 (focal), TTF1 (focal), and CD10 (luminal) and negative for the estrogen receptor, progesterone receptor, and WT1. One month after surgery, computed tomography revealed multiple liver metastases. Additional immunohistochemistry for therapeutic targets revealed that the tumor cells were weakly positive for human epidermal growth factor receptor 2 (focal; score 1+), pan-tropomyosin receptor kinase-negative, programmed death-ligand 1-negative, and PMS2 and MSH6 intact. The companion homologous recombination deficiency test (MyChoice
    MeSH term(s) Female ; Humans ; Middle Aged ; Ovarian Cysts ; Ovarian Neoplasms/diagnosis ; Ovarian Neoplasms/surgery ; Ovarian Neoplasms/pathology ; Adenocarcinoma/pathology ; Liver Neoplasms/diagnosis ; Liver Neoplasms/surgery
    Language English
    Publishing date 2023-06-21
    Publishing country United States
    Document type Case Reports ; Review ; Journal Article
    ZDB-ID 1336393-1
    ISSN 1940-2465 ; 1066-8969
    ISSN (online) 1940-2465
    ISSN 1066-8969
    DOI 10.1177/10668969231183631
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 4500: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  3. Article ; Online: Radiologically Undetectable Latent Pulmonary Lymphocyte Infiltration Suggesting the Need for Early Glucocorticoid Therapy: An Autopsy Case of Rapidly Progressive COVID-19 Pneumonia with Lymphopenia.

    Tanomogi, Naoki / Otani, Toshinori / Araki, Junko / Sugitani, Ayumi / Itagaki, Shingo / Kiriu, Takahiro / Shimada, Kota

    Internal medicine (Tokyo, Japan)

    2021  Volume 60, Issue 13, Page(s) 2145–2148

    Abstract: We herein report a fatal case of coronavirus disease 2019 (COVID-19) pneumonia with rapid progression of respiratory failure and lymphopenia. Excessive recruitment and sequestration of lymphocytes in the lung were suggested as the pathophysiology ... ...

    Abstract We herein report a fatal case of coronavirus disease 2019 (COVID-19) pneumonia with rapid progression of respiratory failure and lymphopenia. Excessive recruitment and sequestration of lymphocytes in the lung were suggested as the pathophysiology underlying COVID-19-associated lymphopenia. Interestingly, the autopsy in this case revealed lymphocytic infiltration in the lungs even at sites that appeared normal on autopsy imaging. These findings suggest that in COVID-19 cases with risk factors of severe exacerbation, early glucocorticoid administration should be considered, especially if lymphopenia is present, even if the imaging findings show only mild abnormalities.
    MeSH term(s) Autopsy ; COVID-19 ; Glucocorticoids/therapeutic use ; Humans ; Lung/diagnostic imaging ; Lymphocytes ; Lymphopenia ; SARS-CoV-2
    Chemical Substances Glucocorticoids
    Language English
    Publishing date 2021-05-14
    Publishing country Japan
    Document type Journal Article
    ZDB-ID 32371-8
    ISSN 1349-7235 ; 0021-5120 ; 0918-2918
    ISSN (online) 1349-7235
    ISSN 0021-5120 ; 0918-2918
    DOI 10.2169/internalmedicine.7234-21
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 240: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

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