Article: WT1 peptide cancer vaccine.
Nihon rinsho. Japanese journal of clinical medicine
2018 Volume 75, Issue 2, Page(s) 263–269
Abstract: Wilms'tumor gene 1(WT1) is a leukemia cell-specific marker, and WT1 protein is pan- tumor-associated antigen (TAA) that was ranked as a top among 75 TAAs. WT1 peptide vaccine has been performing for over 800 patients with 58 kinds of malignancies ... ...
Abstract | Wilms'tumor gene 1(WT1) is a leukemia cell-specific marker, and WT1 protein is pan- tumor-associated antigen (TAA) that was ranked as a top among 75 TAAs. WT1 peptide vaccine has been performing for over 800 patients with 58 kinds of malignancies including leukemia and various types of solid tumors. Clinical results are promising, and adverse effects are limited to skin eruption on the vaccine injection sites. Two types of WT1 peptide vaccines are under clinical studies by pharmaceutical companies for the development of medicine. |
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MeSH term(s) | Cancer Vaccines/immunology ; Cancer Vaccines/therapeutic use ; Humans ; Immunotherapy ; Neoplasms/immunology ; Neoplasms/therapy ; Vaccines, Subunit/immunology ; Vaccines, Subunit/therapeutic use ; WT1 Proteins/immunology |
Chemical Substances | Cancer Vaccines ; Vaccines, Subunit ; WT1 Proteins ; WT1 protein, human |
Language | Japanese |
Publishing date | 2018-12-16 |
Publishing country | Japan |
Document type | Journal Article |
ZDB-ID | 390903-7 |
ISSN | 0047-1852 |
ISSN | 0047-1852 |
Database | MEDical Literature Analysis and Retrieval System OnLINE |
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