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  1. Article ; Online: Using the heme peroxidase APEX2 to probe intracellular H

    Eid, Mohammad / Barayeu, Uladzimir / Sulková, Kateřina / Aranda-Vallejo, Carla / Dick, Tobias P

    Nature communications

    2024  Volume 15, Issue 1, Page(s) 1239

    Abstract: Currently available genetically encoded ... ...

    Abstract Currently available genetically encoded H
    MeSH term(s) Heme ; Hydrogen Peroxide ; Oxidation-Reduction ; Peroxidases/chemistry ; Peroxidases/metabolism ; Sulfhydryl Compounds
    Chemical Substances Heme (42VZT0U6YR) ; Hydrogen Peroxide (BBX060AN9V) ; Peroxidases (EC 1.11.1.-) ; Sulfhydryl Compounds
    Language English
    Publishing date 2024-02-09
    Publishing country England
    Document type Journal Article
    ZDB-ID 2553671-0
    ISSN 2041-1723 ; 2041-1723
    ISSN (online) 2041-1723
    ISSN 2041-1723
    DOI 10.1038/s41467-024-45511-9
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Poly(4-Styrenesulfonic Acid-co-maleic Anhydride)-Coated NaGdF₄:Yb,Tb,Nd Nanoparticles with Luminescence and Magnetic Properties for Imaging of Pancreatic Islets and β-Cells

    Shapoval, Oleksandr / Engstová, Hana / Jirák, Daniel / Drahokoupil, Jan / Sulková, Kateřina / Berková, Zuzana / Pop-Georgievski, Ognen / Holendová, Blanka / Ježek, Petr / Horák, Daniel

    ACS applied materials & interfaces. 2022 Apr. 13, v. 14, no. 16

    2022  

    Abstract: Novel Yb,Tb,Nd-doped GdF₃ and NaGdF₄ nanoparticles were synthesized by a coprecipitation method in ethylene glycol (EG) in the presence of the poly(4-styrenesulfonic acid-co-maleic anhydride) stabilizer. The particle size and morphology, crystal ... ...

    Abstract Novel Yb,Tb,Nd-doped GdF₃ and NaGdF₄ nanoparticles were synthesized by a coprecipitation method in ethylene glycol (EG) in the presence of the poly(4-styrenesulfonic acid-co-maleic anhydride) stabilizer. The particle size and morphology, crystal structure, and phase change were controlled by adjusting the PSSMA concentration and source of fluoride anions in the reaction. Doping of Yb³⁺, Tb³⁺, and Nd³⁺ ions in the NaGdF₄ host nanoparticles induced luminescence under ultraviolet and near-infrared excitation and high relaxivity in magnetic resonance (MR) imaging (MRI). In vitro toxicity of the nanoparticles and their cellular uptake efficiency were determined in model rat pancreatic β-cells (INS-1E). As the NaGdF₄:Yb,Tb,Nd@PSSMA-EG nanoparticles were non-toxic and possessed good luminescence and magnetic properties, they were applicable for in vitro optical and MRI of isolated pancreatic islets in phantoms. The superior contrast was achieved for in vivo T₂*-weighted MR images of the islets transplanted under the kidney capsule to mice in preclinical trials.
    Keywords anhydrides ; coprecipitation ; crystal structure ; ethylene glycol ; kidneys ; luminescence ; magnetism ; particle size ; phase transition ; rats ; stabilizers ; toxicity
    Language English
    Dates of publication 2022-0413
    Size p. 18233-18247.
    Publishing place American Chemical Society
    Document type Article
    ISSN 1944-8252
    DOI 10.1021/acsami.2c04274
    Database NAL-Catalogue (AGRICOLA)

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  3. Article ; Online: Poly(4-Styrenesulfonic Acid-

    Shapoval, Oleksandr / Engstová, Hana / Jirák, Daniel / Drahokoupil, Jan / Sulková, Kateřina / Berková, Zuzana / Pop-Georgievski, Ognen / Holendová, Blanka / Ježek, Petr / Horák, Daniel

    ACS applied materials & interfaces

    2022  Volume 14, Issue 16, Page(s) 18233–18247

    Abstract: Novel Yb,Tb,Nd-doped ... ...

    Abstract Novel Yb,Tb,Nd-doped GdF
    MeSH term(s) Animals ; Islets of Langerhans/diagnostic imaging ; Luminescence ; Magnetic Resonance Imaging/methods ; Maleic Anhydrides ; Mice ; Nanoparticles/chemistry ; Rats
    Chemical Substances Maleic Anhydrides
    Language English
    Publishing date 2022-04-13
    Publishing country United States
    Document type Journal Article
    ISSN 1944-8252
    ISSN (online) 1944-8252
    DOI 10.1021/acsami.2c04274
    Database MEDical Literature Analysis and Retrieval System OnLINE

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