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  1. Book ; Online: Electronic Literature as Digital Humanities

    Grigar, Dene / O'Sullivan, James

    Contexts, Forms, and Practices

    (Electronic Literature)

    2021  

    Series title Electronic Literature
    Keywords Literature: history & criticism ; Technology: general issues ; Media studies ; Digital ; literature ; electronic ; ontological approach ; digital humanities ; technology ; development ; e-poetry ; database ; cyberfeminist ; augmented reality ; bots ; hypertext
    Language 0|e
    Size 1 electronic resource (392 pages)
    Publisher Bloomsbury Academic
    Publishing place New York
    Document type Book ; Online
    Note English ; Open Access
    HBZ-ID HT021620511
    ISBN 9781501363498 ; 1501363492
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Article: Œnothera Biennis in Mucous Inflammations.

    Sullivan, James F

    The Southern medical record

    2022  Volume 8, Issue 2, Page(s) 46

    Language English
    Publishing date 2022-08-26
    Publishing country United States
    Document type Journal Article
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Protecting populations from the health harms of air pollution.

    Sullivan, James / Sorensen, Cecilia

    BMJ (Clinical research ed.)

    2023  Volume 383, Page(s) 2020

    MeSH term(s) Humans ; Air Pollution/adverse effects ; Air Pollution/prevention & control ; Air Pollution/analysis ; Air Pollutants/adverse effects ; Air Pollutants/analysis ; Particulate Matter/adverse effects ; Particulate Matter/analysis ; Environmental Exposure/adverse effects ; Environmental Exposure/prevention & control
    Chemical Substances Air Pollutants ; Particulate Matter
    Language English
    Publishing date 2023-10-04
    Publishing country England
    Document type Editorial ; Comment
    ZDB-ID 1362901-3
    ISSN 1756-1833 ; 0959-8154 ; 0959-8146 ; 0959-8138 ; 0959-535X ; 1759-2151
    ISSN (online) 1756-1833
    ISSN 0959-8154 ; 0959-8146 ; 0959-8138 ; 0959-535X ; 1759-2151
    DOI 10.1136/bmj.p2020
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Another Plea for Caution When Using Survey Income Data From the Far-Left Tail.

    Sullivan, James X

    Demography

    2020  Volume 57, Issue 6, Page(s) 2377–2381

    MeSH term(s) Humans ; Income ; Poverty ; Social Problems ; Surveys and Questionnaires
    Language English
    Publishing date 2020-11-19
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 280612-5
    ISSN 1533-7790 ; 0070-3370
    ISSN (online) 1533-7790
    ISSN 0070-3370
    DOI 10.1007/s13524-020-00936-x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: A Cautionary Tale of Using Data From the Tail.

    Sullivan, James X

    Demography

    2020  Volume 57, Issue 6, Page(s) 2361–2368

    MeSH term(s) Humans ; Poverty ; Social Problems ; United States
    Language English
    Publishing date 2020-10-15
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 280612-5
    ISSN 1533-7790 ; 0070-3370
    ISSN (online) 1533-7790
    ISSN 0070-3370
    DOI 10.1007/s13524-020-00926-z
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: c-Abl Inhibitors as Disease-Modifying Therapies for Parkinson's Disease: Gaps and Opportunities.

    Merchant, Kalpana / Sullivan, James

    Movement disorders : official journal of the Movement Disorder Society

    2022  Volume 37, Issue 1, Page(s) 3–5

    MeSH term(s) Brain ; Humans ; Neuroprotective Agents/pharmacology ; Parkinson Disease/drug therapy
    Chemical Substances Neuroprotective Agents
    Language English
    Publishing date 2022-01-18
    Publishing country United States
    Document type Editorial
    ZDB-ID 607633-6
    ISSN 1531-8257 ; 0885-3185
    ISSN (online) 1531-8257
    ISSN 0885-3185
    DOI 10.1002/mds.28907
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Book ; Online: Primary Source Reflection 1

    Sullivan, James

    Community Reflections

    COVID-19 Pandemic Personal Experience

    2020  

    Abstract: Class assignment for HI-102C, Western Civilization Since 1500, Professor Kelly Marino. My paper reflects on my time during the COVID-19 pandemic. I told my personal experiences and moments that I have been through. From March to September. I also related ...

    Abstract Class assignment for HI-102C, Western Civilization Since 1500, Professor Kelly Marino. My paper reflects on my time during the COVID-19 pandemic. I told my personal experiences and moments that I have been through. From March to September. I also related how the COVID-19 pandemic relates to The Bubonic Plague.
    Keywords Higher Education ; Virus Diseases ; covid19
    Publishing date 2020-09-25T07:00:00Z
    Publisher DigitalCommons@SHU
    Publishing country us
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article ; Online: Retinal vascular remodeling in photoreceptor degenerative disease.

    Nguyen, Matthew / Sullivan, James / Shen, Wen

    Experimental eye research

    2023  Volume 234, Page(s) 109566

    Abstract: Abnormal vasculature in the retina, specifically tortuous vessels and capillary degeneration, is common in many of the most prevalent retinal degenerative diseases, currently affecting millions of people across the world. However, the formation and ... ...

    Abstract Abnormal vasculature in the retina, specifically tortuous vessels and capillary degeneration, is common in many of the most prevalent retinal degenerative diseases, currently affecting millions of people across the world. However, the formation and development of abnormal vasculature in the context of retinal degenerative diseases are still poorly understood. The FVB/N (rd1) and rd10 mice are well-studied animal models of retinal degenerative diseases, but how photoreceptor degeneration leads to vascular abnormality in the diseases remains to be elucidated. Here, we used advancements in confocal microscopy, immunohistochemistry, and image analysis software to systematically characterize the pathological vasculature in the FVB/N (rd1) and rd10 mice, known as a chronic, rapid and slower retinal degenerative model, respectively. We demonstrated that there was plexus-specific vascular degeneration in the retinal trilaminar vascular network paralleled to photoreceptor degeneration in the diseased retinas. We also quantitatively analyzed the vascular structural architecture in the wild-type and diseased retinas to provide valuable information on vascular remodeling in retinal degenerative disease.
    MeSH term(s) Mice ; Animals ; Vascular Remodeling ; Mice, Inbred C57BL ; Retina/pathology ; Photoreceptor Cells/pathology ; Retinal Degeneration/pathology ; Disease Models, Animal ; Photoreceptor Cells, Vertebrate/pathology
    Language English
    Publishing date 2023-07-07
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Research Support, U.S. Gov't, Non-P.H.S. ; Research Support, N.I.H., Extramural
    ZDB-ID 80122-7
    ISSN 1096-0007 ; 0014-4835
    ISSN (online) 1096-0007
    ISSN 0014-4835
    DOI 10.1016/j.exer.2023.109566
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Book ; Online: Deterministic Langevin Unconstrained Optimization with Normalizing Flows

    Sullivan, James M. / Seljak, Uros

    2023  

    Abstract: We introduce a global, gradient-free surrogate optimization strategy for expensive black-box functions inspired by the Fokker-Planck and Langevin equations. These can be written as an optimization problem where the objective is the target function to ... ...

    Abstract We introduce a global, gradient-free surrogate optimization strategy for expensive black-box functions inspired by the Fokker-Planck and Langevin equations. These can be written as an optimization problem where the objective is the target function to maximize minus the logarithm of the current density of evaluated samples. This objective balances exploitation of the target objective with exploration of low-density regions. The method, Deterministic Langevin Optimization (DLO), relies on a Normalizing Flow density estimate to perform active learning and select proposal points for evaluation. This strategy differs qualitatively from the widely-used acquisition functions employed by Bayesian Optimization methods, and can accommodate a range of surrogate choices. We demonstrate superior or competitive progress toward objective optima on standard synthetic test functions, as well as on non-convex and multi-modal posteriors of moderate dimension. On real-world objectives, such as scientific and neural network hyperparameter optimization, DLO is competitive with state-of-the-art baselines.

    Comment: 31 pages, 9 figures, 1 table, submitted to JOGO
    Keywords Computer Science - Machine Learning ; Mathematics - Optimization and Control
    Subject code 510
    Publishing date 2023-10-01
    Publishing country us
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  10. Article ; Online: Utilization of glucocorticoids among White and Black patients with systemic lupus erythematosus: Observations from the enrollment visit of a prospective registry.

    Sullivan, James K / Littlejohn, Emily A

    Lupus

    2021  Volume 30, Issue 14, Page(s) 2298–2303

    Abstract: Background: Black patients with systemic lupus erythematosus (SLE) face higher rates of morbidity and mortality compared to White patients. Long-term glucocorticoid use has been associated with worse health outcomes among patients with SLE. We sought to ...

    Abstract Background: Black patients with systemic lupus erythematosus (SLE) face higher rates of morbidity and mortality compared to White patients. Long-term glucocorticoid use has been associated with worse health outcomes among patients with SLE. We sought to quantify chronic glucocorticoid use among Black and White patients with SLE within a prospective registry.
    Methods: Using enrollment data from a registry at a large academic institution, we compared glucocorticoid use among Black and White patients with SLE. Multivariable logistic regression of race and glucocorticoid use was performed, adjusting for covariates exhibiting a bivariate association with glucocorticoids at significance level
    Results: 114 White participants (mean age 45; standard deviation (SD) 15) and 59 Black participants (mean age 42; SD 14) were analyzed. White participants had mean SLEDAI-2K score of 3.7 (SD 5.2). Black participants had mean SLEDAI-2K scores of 6.3 (SD 6.0). Among Black participants, 43 (72%) utilized glucocorticoids compared to White participants 39 (34%) (unadjusted odds ratio (OR) 5.17; 95% confidence interval (CI) 2.59-10.33). We did not observe differences between unadjusted hydroxychloroquine (OR 0.69; 95% CI 0.28-1.65) or conventional disease-modifying anti-rheumatic drug (cDMARD) (OR 1.07; 95% CI 0.57-2.01) utilization among Black and White participants. SLEDAI-2K, disability, recent hospitalization, and past or present hydroxychloroquine or cDMARD use were included in a logistic regression model. Adjusting for covariates, Black participants were more likely to be on glucocorticoids (adjusted OR 5.69; 95% CI 2.17-14.96);
    Conclusion: Adjusting for disease activity and other medications, Black patients had more exposure to chronic glucocorticoids than White patients in the Cleveland Clinic SLE registry. These patients may face increased glucocorticoid-related morbidity, which could contribute significantly to long-term health outcomes and utilization of health care resources. Future research in larger, more diverse registries should be conducted to further characterize patterns of glucocorticoid use.
    MeSH term(s) Adult ; Antirheumatic Agents/therapeutic use ; Glucocorticoids/therapeutic use ; Humans ; Hydroxychloroquine/therapeutic use ; Lupus Erythematosus, Systemic/drug therapy ; Middle Aged ; Registries ; Severity of Illness Index
    Chemical Substances Antirheumatic Agents ; Glucocorticoids ; Hydroxychloroquine (4QWG6N8QKH)
    Language English
    Publishing date 2021-11-21
    Publishing country England
    Document type Journal Article
    ZDB-ID 1154407-7
    ISSN 1477-0962 ; 0961-2033
    ISSN (online) 1477-0962
    ISSN 0961-2033
    DOI 10.1177/09612033211055817
    Database MEDical Literature Analysis and Retrieval System OnLINE

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