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Article ; Online: A profile of the Grampian Data Safe Haven, a regional Scottish safe haven for health and population data research.

O'Sullivan, Katherine K / Wilde, Katie J

International journal of population data science

2023 Volume 4, Issue 2, Page(s) 1817

Abstract: There has been a recent emphasis to establish and codify large-scale or national Trusted Research Environments (TREs) in the United Kingdom, with a view to limit smaller, local TREs. The basis for this argument is that it avoids duplication of ... ...

Abstract	There has been a recent emphasis to establish and codify large-scale or national Trusted Research Environments (TREs) in the United Kingdom, with a view to limit smaller, local TREs. The basis for this argument is that it avoids duplication of infrastructure, information governance, privacy risks, monopolies and will promote innovation, particularly with commercial partners. However, the work around establishing TREs in the UK largely ignores the long-established local TRE landscape in Scotland, and the way in which local TREs can actually improve data quality, solve technical architecture challenges, promote information governance and risk minimisation, and encourage innovation and collaboration (both academic and commercial). This data centre profile focuses on the Grampian Data Safe Haven (DaSH), a secure, virtual healthcare data analysis and storage centre located in Aberdeen, Scotland. DaSH was co-established by the NHS Grampian Health Board and University of Aberdeen to allow for the secure processing and linking of health data for the Grampian and Scottish population when it is not practicable to obtain consent from individual patients. As an established trusted research environment now in its 10
Language	English
Publishing date	2023-03-16
Publishing country	Wales
Document type	Journal Article
ISSN	2399-4908
ISSN (online)	2399-4908
DOI	10.23889/ijpds.v4i2.1817
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Article ; Online: Multi-Resin Masked Stereolithography (MSLA) 3D Printing for Rapid and Inexpensive Prototyping of Microfluidic Chips with Integrated Functional Components.

Ahmed, Isteaque / Sullivan, Katherine / Priye, Aashish

Biosensors

2022 Volume 12, Issue 8

Abstract: Stereolithography based 3D printing of microfluidics for prototyping has gained a lot of attention due to several advantages such as fast production, cost-effectiveness, and versatility over traditional photolithography-based microfabrication techniques. ...

Abstract	Stereolithography based 3D printing of microfluidics for prototyping has gained a lot of attention due to several advantages such as fast production, cost-effectiveness, and versatility over traditional photolithography-based microfabrication techniques. However, existing consumer focused SLA 3D printers struggle to fabricate functional microfluidic devices due to several challenges associated with micron-scale 3D printing. Here, we explore the origins and mechanism of the associated failure modes followed by presenting guidelines to overcome these challenges. The prescribed method works completely with existing consumer class inexpensive SLA printers without any modifications to reliably print PDMS cast microfluidic channels with channel sizes as low as ~75 μm and embedded channels with channel sizes as low ~200 μm. We developed a custom multi-resin formulation by incorporating Polyethylene glycol diacrylate (PEGDA) and Ethylene glycol polyether acrylate (EGPEA) as the monomer units to achieve micron sized printed features with tunable mechanical and optical properties. By incorporating multiple resins with different mechanical properties, we were able to achieve spatial control over the stiffness of the cured resin enabling us to incorporate both flexible and rigid components within a single 3D printed microfluidic chip. We demonstrate the utility of this technique by 3D printing an integrated pressure-actuated pneumatic valve (with flexible cured resin) in an otherwise rigid and clear microfluidic device that can be fabricated in a one-step process from a single CAD file. We also demonstrate the utility of this technique by integrating a fully functional finger-actuated microfluidic pump. The versatility and accessibility of the demonstrated fabrication method have the potential to reduce our reliance on expensive and time-consuming photolithographic techniques for microfluidic chip fabrication and thus drastically lowering our barrier to entry in microfluidics research.
MeSH term(s)	Lab-On-A-Chip Devices ; Microfluidics/methods ; Microtechnology ; Printing, Three-Dimensional ; Stereolithography
Language	English
Publishing date	2022-08-17
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2662125-3
ISSN	2079-6374 ; 2079-6374
ISSN (online)	2079-6374
ISSN	2079-6374
DOI	10.3390/bios12080652
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Article ; Online: Stress, eating and weight change in first year students: the moderating role of self-compassion.

Sullivan, Katherine / Kuijer, Roeline G / Kerr, Jessica A

Psychology & health

2022 , Page(s) 1–17

Abstract: Objective: The current study sought to examine the drivers of weight change in first-year university students. The study examined the moderating role of self-compassion in the relationship between stress, eating and weight change. Specifically, we ... ...

Abstract	Objective: The current study sought to examine the drivers of weight change in first-year university students. The study examined the moderating role of self-compassion in the relationship between stress, eating and weight change. Specifically, we expected that students low in self-compassion would respond to stress with unhealthy eating resulting in weight gain. We expected students high in self-compassion to be buffered from the negative effects of stress (moderated mediation model). Methods: First-year university students in New Zealand ( Results: Students gained a significant 1.45 kg (SD 3.67 kg) of body weight. Self-compassion moderated the relationship between stress and changes in: (a) unhealthy (but not healthy) food intake, and (b) body weight. For those with low self-compassion, perceived stress was significantly related to an increase in BMI and, unexpectedly, to a decrease in unhealthy food intake. Changes in food intake did not explain changes in BMI. Conclusion: Wellbeing interventions for university students to reduce negative effects of stress should incorporate concurrent training in self-compassion.
Language	English
Publishing date	2022-09-16
Publishing country	England
Document type	Journal Article
ZDB-ID	625255-2
ISSN	1476-8321 ; 0887-0446
ISSN (online)	1476-8321
ISSN	0887-0446
DOI	10.1080/08870446.2022.2122461
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Zs.A 2856: Show issues

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Article ; Online: Body composition estimates using a 2D image analysis system across different environmental conditions: An agreement study.

Metoyer, Casey J / Sullivan, Katherine / Winchester, Lee J / Richardson, Mark T / Esco, Michael R / Fedewa, Michael V

Journal of biophotonics

2024 Volume 17, Issue 4, Page(s) e202300518

Abstract: Purpose: This study examined the agreement between %Fat measurements using a smartphone-based application (IMAGE) across different environmental conditions.: Methods: A single reference image was obtained using an 8 MP smartphone camera under Ambient ...

Abstract	Purpose: This study examined the agreement between %Fat measurements using a smartphone-based application (IMAGE) across different environmental conditions. Methods: A single reference image was obtained using an 8 MP smartphone camera under Ambient Light in front of a white background. Additional photos were obtained using a 0.7 MP, 5 MP, and 12 MP smartphone cameras; low-, moderate-, and bright-lighting conditions; and various color backgrounds including black, green, orange, and gray. Results: %Fat measured using the 0.7 MP camera (27.8 ± 6.2 %Fat) was higher than the reference (26.8 ± 6.1 %Fat) (p < 0.001). The black (32.0 ± 12.0 %Fat), green (27.5 ± 6.3 %Fat), and gray (27.8 ± 6.3 %Fat) backgrounds yielded higher %Fat than the white (p = 0.03, 0.01, and 0.001). All camera, lighting, and background conditions were strongly correlated with the reference (all intraclass correlation coefficient [ICC] >0.98, all standard error of the estimate [SEE] <1.5 %Fat, all p < 0.001), except the black background which yielded poorer agreement with the white background (ICC = 0.69, SEE = 4.5%, p < 0.001). Conclusion: %Fat from IMAGE were strongly correlated across various environmental conditions.
MeSH term(s)	Smartphone ; Image Processing, Computer-Assisted/methods ; Lighting ; Body Composition
Language	English
Publishing date	2024-01-28
Publishing country	Germany
Document type	Journal Article
ZDB-ID	2390063-5
ISSN	1864-0648 ; 1864-063X
ISSN (online)	1864-0648
ISSN	1864-063X
DOI	10.1002/jbio.202300518
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Zs.A 6723: Show issues

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Article ; Online: Agreement between ultrasound protocols for the estimation of body fat percentage: Comparison to a four-compartment model.

Sullivan, Katherine / Metoyer, Casey J / Winchester, Lee J / Esco, Michael R / Fedewa, Michael V

Clinical physiology and functional imaging

2023 Volume 43, Issue 5, Page(s) 373–381

Abstract: The purpose of this study was to examine the agreement between body fat percentage (%Fat) estimates derived from a standardized ultrasound protocol (% ... ...

Abstract	The purpose of this study was to examine the agreement between body fat percentage (%Fat) estimates derived from a standardized ultrasound protocol (%Fat
MeSH term(s)	Humans ; Adipose Tissue/diagnostic imaging ; Body Composition/physiology ; Ultrasonography ; Sports ; Absorptiometry, Photon ; Skinfold Thickness ; Reproducibility of Results
Language	English
Publishing date	2023-06-04
Publishing country	England
Document type	Journal Article
ZDB-ID	2071203-0
ISSN	1475-097X ; 1475-0961
ISSN (online)	1475-097X
ISSN	1475-0961
DOI	10.1111/cpf.12835
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Zs.A 1650: Show issues

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Article ; Online: Impact of Statewide Statute Limiting Days' Supply to Opioid-Naive Patients.

Sullivan, Katherine J / Gabella, Barbara / Ziegler, Katherine / Tolle, Heather / Giano, Zachary / Hoppe, Jason

American journal of preventive medicine

2023 Volume 66, Issue 1, Page(s) 112–118

Abstract: Introduction: To address the ongoing opioid crisis, states use policy enactment to restrict prescribing by licensed healthcare providers and mandate the use of Prescription Drug Monitoring Programs. There have been mixed results regarding the ... ...

Abstract	Introduction: To address the ongoing opioid crisis, states use policy enactment to restrict prescribing by licensed healthcare providers and mandate the use of Prescription Drug Monitoring Programs. There have been mixed results regarding the effectiveness of such state policies. The purpose of this study is to evaluate the impact of Colorado Senate Bill 18-022, which limits opioid prescriptions to ≤7-day supply among patients without an opioid prescription in the previous year (i.e., are opioid naive). Methods: This is a retrospective interrupted time-series analysis of opioid prescribing to evaluate the weekly percentage of opioid prescriptions consistent with statutory limits for ≤7-day supply among opioid-naive patients before and after enactment using Prescription Drug Monitoring Programs data from May 21, 2017 to May 25, 2019. Statistical analysis was performed in 2021-2022. Results: The weekly percentage of opioid prescriptions ≤7-day supply increased by an average of 0.12% per week (p<0.0001) from 79.7% to 87.4% in the week before enactment. The week after enactment, the average increased by 0.2% (p=0.67). The year after enactment, the average weekly percentage change was 0.07% per week, a 0.05% decrease (p=0.01). Conclusions: Statutory limits on days' supply among opioid-naive patients had little impact on opioid prescribing in Colorado. Legislating limits on opioid prescribing should be evaluated using Prescription Drug Monitoring Program data and considered for deimplementation when not impactful.
MeSH term(s)	Humans ; Analgesics, Opioid/therapeutic use ; Retrospective Studies ; Practice Patterns, Physicians' ; Prescriptions ; Prescription Drug Monitoring Programs ; Drug Prescriptions
Chemical Substances	Analgesics, Opioid
Language	English
Publishing date	2023-08-20
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	632646-8
ISSN	1873-2607 ; 0749-3797
ISSN (online)	1873-2607
ISSN	0749-3797
DOI	10.1016/j.amepre.2023.08.015
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Zs.A 2096: Show issues

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Article: The Reliability of CT Scan Measurements of Pelvic Incidence in the Evaluation of Adult Spondylolisthesis.

Shi, Jinhui / Kurra, Swamy / Danaher, Michael / Bailey, Frank / Sullivan, Katherine H / Lavelle, William

Cureus

2022 Volume 14, Issue 1, Page(s) e21696

Abstract: Background: Pelvic incidence (PI) has been described as a parameter that may be a risk factor for lumbar spondylolisthesis (SPL). Studies have reported PI measurement is more precise in CT scans. Very limited studies have measured PI using CT scans to ... ...

Abstract	Background: Pelvic incidence (PI) has been described as a parameter that may be a risk factor for lumbar spondylolisthesis (SPL). Studies have reported PI measurement is more precise in CT scans. Very limited studies have measured PI using CT scans to evaluate SPL. We analyzed the reliability of CT scans to measure PI to evaluate SPL and compared it to patients without SPL. Methods: A retrospective, cross-sectional study of PI in a consecutive cohort of patients' pelvic/abdominal CT scans from an emergency room visit at a Level 1 trauma center between 2013 and 2016. Inclusion criteria was >18 years and had no lumbar or pelvis fracture. A total of 361 patients met the criteria for our study. We documented age, average PI, and SPL (type, grading, and location). Sagittal CT scans were used to measure PI (between hip axis to an orthogonal line originating at the center of superior end plate axis of first sacral vertebra). Patients were categorized: with SPL (n=45) and without SPL (n=316). Subgroups were comprised based on the location of SPL (L4/L5 and L5/S1) and type of SPL. Analysis of variance (ANOVA) and chi-square tests used; p≤0.05 considered statistically significant. Results: Patients with SPL were significantly older versus patients without SPL, p=0.006. There were no statistical differences in PI between patients with and without SPL (p=0.29); between subgroups of patients with SPL at L4/L5 and without SPL (p=0.52); between subgroups with type of SPL at L4/L5 and without SPL (p=0.47); and between SPL patients at L5/S1 and without SPL (p=0.40). Patients with isthmic SPL at L5/S1 had nearly significant higher PIs (p=0.06) compared to those without SPL or with degenerative SPL at L5/S1. There was a trend towards higher PI in Grade 2 SPL patients at L5/S1, p=0.18. Conclusions: Patients with SPL were significantly older than patients without SPL. The two trends observed were that PI was higher in patients with isthmic SPL at L5/S1 and an increased PI with Grade 2 isthmic SPL at L5/S1. Our reported CT PI measurements correlated with reported PI measured using standard radiographs in patients with SPL. CT scans may be a reliable modality to evaluate adult SPL.
Language	English
Publishing date	2022-01-28
Publishing country	United States
Document type	Journal Article
ZDB-ID	2747273-5
ISSN	2168-8184
ISSN	2168-8184
DOI	10.7759/cureus.21696
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Article ; Online: Creating an ignorance-base: Exploring known unknowns in the scientific literature.

Boguslav, Mayla R / Salem, Nourah M / White, Elizabeth K / Sullivan, Katherine J / Bada, Michael / Hernandez, Teri L / Leach, Sonia M / Hunter, Lawrence E

Journal of biomedical informatics

2023 Volume 143, Page(s) 104405

Abstract: Background: Scientific discovery progresses by exploring new and uncharted territory. More specifically, it advances by a process of transforming unknown unknowns first into known unknowns, and then into knowns. Over the last few decades, researchers ... ...

Abstract	Background: Scientific discovery progresses by exploring new and uncharted territory. More specifically, it advances by a process of transforming unknown unknowns first into known unknowns, and then into knowns. Over the last few decades, researchers have developed many knowledge bases to capture and connect the knowns, which has enabled topic exploration and contextualization of experimental results. But recognizing the unknowns is also critical for finding the most pertinent questions and their answers. Prior work on known unknowns has sought to understand them, annotate them, and automate their identification. However, no knowledge-bases yet exist to capture these unknowns, and little work has focused on how scientists might use them to trace a given topic or experimental result in search of open questions and new avenues for exploration. We show here that a knowledge base of unknowns can be connected to ontologically grounded biomedical knowledge to accelerate research in the field of prenatal nutrition. Results: We present the first ignorance-base, a knowledge-base created by combining classifiers to recognize ignorance statements (statements of missing or incomplete knowledge that imply a goal for knowledge) and biomedical concepts over the prenatal nutrition literature. This knowledge-base places biomedical concepts mentioned in the literature in context with the ignorance statements authors have made about them. Using our system, researchers interested in the topic of vitamin D and prenatal health were able to uncover three new avenues for exploration (immune system, respiratory system, and brain development) by searching for concepts enriched in ignorance statements. These were buried among the many standard enriched concepts. Additionally, we used the ignorance-base to enrich concepts connected to a gene list associated with vitamin D and spontaneous preterm birth and found an emerging topic of study (brain development) in an implied field (neuroscience). The researchers could look to the field of neuroscience for potential answers to the ignorance statements. Conclusion: Our goal is to help students, researchers, funders, and publishers better understand the state of our collective scientific ignorance (known unknowns) in order to help accelerate research through the continued illumination of and focus on the known unknowns and their respective goals for scientific knowledge.
MeSH term(s)	Female ; Humans ; Infant, Newborn ; Knowledge ; Knowledge Bases ; Premature Birth ; Publications ; Vitamin D ; Natural Language Processing
Chemical Substances	Vitamin D (1406-16-2)
Language	English
Publishing date	2023-06-01
Publishing country	United States
Document type	Journal Article ; Research Support, N.I.H., Extramural
ZDB-ID	2057141-0
ISSN	1532-0480 ; 1532-0464
ISSN (online)	1532-0480
ISSN	1532-0464
DOI	10.1016/j.jbi.2023.104405
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Article ; Online: Disparities in physical activity between sexual minority and heterosexual women: A systematic review and meta-analysis.

Sullivan, Katherine / Simmang, Madelyn K / Aguiar, Elroy J / Winchester, Lee J / Wind, Stefanie A / Esco, Michael R / Fedewa, Michael V

Preventive medicine

2023 Volume 175, Page(s) 107708

Abstract: Research examining potential differences in physical activity (PA) between sexual minority women (SMW) and heterosexual women have yielded inconsistent results.: Objective: Therefore, the purpose of this systematic review and meta-analysis is to ... ...

Abstract	Research examining potential differences in physical activity (PA) between sexual minority women (SMW) and heterosexual women have yielded inconsistent results. Objective: Therefore, the purpose of this systematic review and meta-analysis is to examine potential differences in PA between SMW and heterosexual women and to identify potential moderators that may partially explain observed differences in PA. Methods: All studies were peer reviewed, published in English, and included a continuous measure of PA for SMW and heterosexual women. A standardized mean difference effect size (ES) was used to compare groups, with random effects models used to estimate a mean ES and 95% CI using a 3-level meta-analysis model to adjust for the correlation between effects nested within studies. Results: The cumulative results of 24 effects gathered from 7 studies indicated there was no difference in PA between SMW (n = 1619) and heterosexual women (n = 103,295) (ES = -0.038, 95%CI -0.179 to 0.102, p = 0.576). Despite no mean differences, moderate-high heterogeneity was observed, indicating that the results were not consistent across effects (I Conclusions: Although the results of the current analysis did not indicate significant differences in PA behaviors between SMW and heterosexual women, age and BMI modify the association and are curvilinear in nature; such that smaller differences in PA were observed between SMW and heterosexual women when samples were middle-aged and overweight.
Language	English
Publishing date	2023-09-17
Publishing country	United States
Document type	Journal Article ; Review
ZDB-ID	184600-0
ISSN	1096-0260 ; 0091-7435
ISSN (online)	1096-0260
ISSN	0091-7435
DOI	10.1016/j.ypmed.2023.107708
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Zs.A 878: Show issues

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Article: Conflict and coffee

Gong, Erick / Sullivan, Katherine A

Journal of African economies Vol. 26, No. 3 , p. 322-341

are higher coffee prices fuelling rebellion in Uganda?

2017 Volume 26, Issue 3, Page(s) 322–341

Author's details	Erick Gong and Katherine A. Sullivan
Keywords	conflict ; commodities ; rebellion ; income shocks
Language	English
Publisher	Univ. Press
Publishing place	Oxford
Document type	Article
ZDB-ID	1106568-0 ; 1494618-x
ISSN	1464-3723 ; 0963-8024
ISSN (online)	1464-3723
ISSN	0963-8024
Database	ECONomics Information System

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