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Article: Occupational Therapy for Functional Impairments Resulting From COVID-19 Infection: A Case Report.

Mannion, Nicole / Sullivan, Nicole

The American journal of occupational therapy : official publication of the American Occupational Therapy Association

2021 Volume 75, Issue Supplement_1, Page(s) 7511210040p1–7511210040p7

Abstract: This case report examines the role of occupational therapy in the recovery of a client who became critically ill with severe acute respiratory syndrome coronavirus 2. In it, we describe evaluation and treatment methods, functional impairments, and ... ...

Abstract	This case report examines the role of occupational therapy in the recovery of a client who became critically ill with severe acute respiratory syndrome coronavirus 2. In it, we describe evaluation and treatment methods, functional impairments, and special considerations when working with a client with severe coronavirus disease 2019 infection. The client was a 43-yr-old Hispanic man treated in a long-term acute-care hospital. Client-centered treatment sessions focused on activities of daily living (ADLs), self-feeding, medication management, and leisure and were implemented in 30- to 45-min sessions 3 times per week for 5 wk. The Activity Measure for Post Acute Care Daily Activities Short Form was used to measure basic mobility, daily activities, and applied cognition in the acute setting. A manual dynamometer was used to measure grip strength, and the Nine-Hole Peg Test was used to measure digit dexterity. Both were used in the context of occupational engagement. Data were collected at evaluation, every 2 wk, and at discharge. The client achieved his goals and demonstrated marked improvement in independence with basic ADLs, leisure activities, bilateral grip strength, and manual dexterity.
MeSH term(s)	Activities of Daily Living ; COVID-19 ; Humans ; Leisure Activities ; Male ; Occupational Therapy ; SARS-CoV-2
Language	English
Publishing date	2021-08-18
Publishing country	United States
Document type	Case Reports
ZDB-ID	219403-x
ISSN	1943-7676 ; 0272-9490 ; 0161-326X
ISSN (online)	1943-7676
ISSN	0272-9490 ; 0161-326X
DOI	10.5014/ajot.2021.049215
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Book ; Online: Virtual Fidgets

Ross, Sam / Sullivan, Nicole / Yoon, Jina

Opportunities and Design Principles for Bringing Fidgeting to Online Learning

2023

Abstract: We present design guidelines for incorporating fidgeting into the virtual world as a tool for students in online lectures. Fidgeting is associated with increased attention and self-regulation, and has the potential to help students focus. Currently there ...

Abstract	We present design guidelines for incorporating fidgeting into the virtual world as a tool for students in online lectures. Fidgeting is associated with increased attention and self-regulation, and has the potential to help students focus. Currently there are no fidgets, physical or virtual, designed for preserving attention specifically in online learning environments, and no heuristics for designing fidgets within this domain. We identify three virtual fidget proxies to serve as design probes for studying student experiences with virtual fidgeting. Through a study of eight students using our virtual fidget proxies in online lectures, we identify eight emergent themes that encompass student experience with virtual fidgeting in lectures. Based on these themes, we present four principles for designing domain-specific virtual fidgets for online lectures. We identify that virtual fidgets for lectures should be context-aware, visually appealing, easy to adopt, and physically interactive. Comment: 6 pages, 3 figures, CHI LBW 2023
Keywords	Computer Science - Human-Computer Interaction
Subject code	629
Publishing date	2023-04-18
Publishing country	us
Document type	Book ; Online
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Article ; Online: Motherhood and DREADD manipulation of the nucleus accumbens weaken established pair bonds in female prairie voles.

Forero, Santiago A / Sailer, Lindsay L / Girčytė, Aistė / Madrid, Jesus E / Sullivan, Nicole / Ophir, Alexander G

Hormones and behavior

2023 Volume 151, Page(s) 105351

Abstract: Monogamous pair bonding has evolved to enhance reproductive success and ensure offspring survival. Although the behavioral and neural mechanisms regulating the formation of pair bonds have been relatively well outlined, how these relationships are ... ...

Abstract	Monogamous pair bonding has evolved to enhance reproductive success and ensure offspring survival. Although the behavioral and neural mechanisms regulating the formation of pair bonds have been relatively well outlined, how these relationships are regulated and maintained across the lifetime of an individual remains relatively unexplored. One way to explore this is to study the maintenance of a social bond across a major life-history transition. The transition to motherhood is among the most poignant moments in the life history of a female, and is associated with significant neural and behavioral changes and shifting priorities. The nucleus accumbens (NAc) is known to modulate social valence and is central to mammalian pair bonding. In this study, we investigated two mechanisms driving variation in bond strength in the socially monogamous prairie vole (Microtus ochrogaster). We manipulated neural activity of the NAc at two distinct stages of life-history, before and after the birth of offspring, to assess how neural activity and social contexts modulate female pair bond strength. Our results showed DREADD (Designer Receptor Exclusively Activated by Designer Drugs) inhibition of the NAc decreases affiliative behavior towards the mating partner, whereas DREADD activation of the NAc increases affiliative behavior of strangers, thereby decreasing social selectivity. We also found a robust "birth effect" on pair bond strength, such that bonds with partners were weakened after the birth of offspring, an effect not attributable to the amount of cohabitation time with a partner. Overall, our data support the hypotheses that NAc activity modulates reward/saliency within the social brain in different ways, and that motherhood comes with a cost for the bond strength between mating partners.
MeSH term(s)	Animals ; Female ; Pair Bond ; Nucleus Accumbens ; Grassland ; Social Behavior ; Arvicolinae/physiology ; DNA-Binding Proteins/pharmacology
Chemical Substances	DNA-Binding Proteins
Language	English
Publishing date	2023-03-30
Publishing country	United States
Document type	Journal Article ; Research Support, U.S. Gov't, Non-P.H.S. ; Research Support, N.I.H., Extramural
ZDB-ID	214409-8
ISSN	1095-6867 ; 0018-506X
ISSN (online)	1095-6867
ISSN	0018-506X
DOI	10.1016/j.yhbeh.2023.105351
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Article ; Online: Student veterans and adjustment to college: Making meaning of military experiences.

Sullivan, Nicole / Freer, Benjamin D / Ulrich, Stefanie

Journal of American college health : J of ACH

2019 Volume 69, Issue 5, Page(s) 503–512

Abstract: Objective: This study examined the relationships among meaning making, military stressor severity, and adjustment to college among student service members/veterans (SSM/Vs).: Participants: Participants were 128 SSM/Vs enrolled in postsecondary ... ...

Abstract	Objective: This study examined the relationships among meaning making, military stressor severity, and adjustment to college among student service members/veterans (SSM/Vs). Participants: Participants were 128 SSM/Vs enrolled in postsecondary education from April to June 2016. Methods: Participants completed online self-report rating scales of stressor severity for their most stressful military event, meaning made of that stressor, and adjustment to college. Results: Regression analyses revealed that made meaning of military stressors was associated with more positive academic, social, and emotional adjustment to college. Stressor severity was not associated with adjustment, nor did made meaning moderate the relationship between stressor severity and adjustment to college. Conclusion: These findings provide preliminary evidence that making meaning of stressful military experiences can promote academic, social, and emotional adjustment to college among SSM/Vs and has implications for incorporating meaning making strategies into university and clinical programs aimed at promoting adjustment to college in this population.
MeSH term(s)	Humans ; Military Personnel ; Self Report ; Students ; Universities ; Veterans
Language	English
Publishing date	2019-11-08
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	604907-2
ISSN	1940-3208 ; 0744-8481
ISSN (online)	1940-3208
ISSN	0744-8481
DOI	10.1080/07448481.2019.1683017
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Article: Effectiveness of Health Promotion, Management, and Maintenance Interventions Within the Scope of Occupational Therapy for Community-Dwelling Older Adults: A Systematic Review.

Berger, Sue / Escher, Anne / Mengle, Emily / Sullivan, Nicole

The American journal of occupational therapy : official publication of the American Occupational Therapy Association

2018 Volume 72, Issue 4, Page(s) 7204190010p1–7204190010p10

Abstract: Objective: This systematic review examined the effectiveness of health promotion, management, and maintenance interventions within the scope of occupational therapy to improve occupational performance and quality of life (QOL) and decrease health care ... ...

Abstract	Objective: This systematic review examined the effectiveness of health promotion, management, and maintenance interventions within the scope of occupational therapy to improve occupational performance and quality of life (QOL) and decrease health care utilization for community-dwelling older adults. Method: Thirty-eight articles representing 36 studies were included in the review. Articles were published 2008-2015 and described studies of participants with a mean age of 65 or older who were living in the community. Results: Strong evidence supports the use of group, individual, or a combination of group and individual interventions to improve occupational performance. Group interventions were also effective at improving QOL. The evidence was insufficient that any of these interventions decreased health care utilization. Conclusion: Addressing health promotion, management, and maintenance is within the scope of occupational therapy practice and has been shown to improve occupational performance and QOL for older adults. Implications for practice and future research are discussed.
MeSH term(s)	Activities of Daily Living ; Aged ; Aging ; Health Behavior ; Health Education ; Health Promotion ; Humans ; Independent Living ; Occupational Therapy ; Quality of Life ; Residential Facilities
Language	English
Publishing date	2018-06-07
Publishing country	United States
Document type	Journal Article ; Systematic Review
ZDB-ID	219403-x
ISSN	1943-7676 ; 0272-9490 ; 0161-326X
ISSN (online)	1943-7676
ISSN	0272-9490 ; 0161-326X
DOI	10.5014/ajot.2018.030346
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Article: Palliative Care in the Hip Fracture Patient.

Sullivan, Nicole M / Blake, Lindsay E / George, Masil / Mears, Simon C

Geriatric orthopaedic surgery & rehabilitation

2019 Volume 10, Page(s) 2151459319849801

Abstract: Introduction: Older patients with hip fracture have a 20% to 30% mortality rate in the year after surgery. Nonoperative care has higher 1-year mortality rates and is generally only pursued in those with an extraordinarily high surgical risk. As the ... ...

Abstract	Introduction: Older patients with hip fracture have a 20% to 30% mortality rate in the year after surgery. Nonoperative care has higher 1-year mortality rates and is generally only pursued in those with an extraordinarily high surgical risk. As the population ages, more patients with hip fracture may fall into this category. The orthopedic surgeon is typically the main consultant responsible for deciding between surgery and conservative management, and the reasoning behind one decision over the other is often poorly understood. We undertook a review to determine decision-making tools for surgery in high-risk patients with hip fracture. Materials and methods: A review was conducted using PubMed to determine articles published using the terms palliative care, conservative care, nonoperative, hip fracture, orthopedic procedures, fracture fixation, and surgery. Our search resulted in 13 articles to review. These were further screened to determine tools for use in surgical decision-making. Results: Several potential decision-making tools were found in our search. The potential tools to identify patients who would benefit from nonoperative treatment included the Palliative Performance Scale for severe dementia, the Lawton Instrumental Activities of Daily Living and Katz Activities of Daily Living scales for prefracture immobility, a combination of clinical signs and laboratory tests to determine risk of imminent death, and the Charlson Comorbidity Score for additional serious comorbidities. No tools have been prospectively tested in a clinical setting. Discussion: Evaluation of each patient using a variety of decision making tools should help the orthopedic surgeon determine which patients would be better suited to non-operative management. After determining the benefit of non-operative care, they must effectively allow the fracture to heal while ameliorating pain. Palliative care physicians can fulfill this role by providing support and symptom relief. Conclusions: Surgical decision-making for hip fracture repair in the elderly patients is not straight forward. Several tools may be helpful to the surgeon in determining who may be better suited for nonoperative care or a palliative care referral. Prospective data do not exist in these decision-making tools.
Language	English
Publishing date	2019-05-30
Publishing country	United States
Document type	Journal Article
ZDB-ID	2589094-3
ISSN	2151-4593 ; 2151-4585
ISSN (online)	2151-4593
ISSN	2151-4585
DOI	10.1177/2151459319849801
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Article ; Online: Understanding Veterans' Causal Attributions of Physical Symptoms.

Kimber, Justin / Sullivan, Nicole / Anastasides, Nicole / Slotkin, Sarah / McAndrew, Lisa M

International journal of behavioral medicine

2020 Volume 28, Issue 3, Page(s) 299–307

Abstract: Background: Illness beliefs are significant contributors to health outcomes. Beliefs about the cause of physical symptoms are considered particularly important among those with medically unexplained symptoms and illnesses (MUS); yet little is known ... ...

Abstract	Background: Illness beliefs are significant contributors to health outcomes. Beliefs about the cause of physical symptoms are considered particularly important among those with medically unexplained symptoms and illnesses (MUS); yet little is known about causal beliefs among those with the most severe MUS (i.e., Veterans). The goal of the current study was to examine Veteran's causal attributions of their physical symptoms. Method: A total of 91 combat Veterans with MUS were surveyed using a mixed-methods design about the cause of their physical symptoms, physical symptom severity, and PTSD symptoms. Causal attributions of physical symptoms were analyzed through thematic response analysis and grouped into categories. Chi-square analysis was used to assess the distribution of causal attribution types across Veterans with varying physical symptom severity and PTSD symptom severity. Results: Veterans with MUS reported an average of 7.9 physical symptoms, and attributed the cause of their symptoms to seven different categories ("Do not Know," "Stress/Mental Health," "Deployment/Environment," "Functional/Symptom," "Medically Explained," "Medically Unexplained Syndrome," and "Lifestyle"). Exploratory chi-square analysis revealed significant differences in causal attributions across physical symptom severity and severity of PTSD symptoms. Veterans with more severe PTSD and Veterans with more severe physical symptoms were more likely to attribute their MUS to stress/mental health or to a medically unexplained syndrome compared with those with low/no PTSD symptoms and physical symptom severity. Veterans with minimal PTSD and Veterans with minimal physical symptom severity were more likely to attribute the cause of their MUS to lifestyle choices (e.g., exercise/diet) compared with those with high PTSD and physical symptom severity. Conclusion: Veterans with MUS endorse multiple, varied causal attributions for their physical symptoms, suggesting more complex causal beliefs than typically assumed. This has important implications for patient-provider communication and development of concordance around MUS treatment.
Language	English
Publishing date	2020-07-20
Publishing country	England
Document type	Journal Article
ZDB-ID	1187972-5
ISSN	1532-7558 ; 1070-5503
ISSN (online)	1532-7558
ISSN	1070-5503
DOI	10.1007/s12529-020-09918-0
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Article ; Online: Treatment and life goals among veterans with Gulf War illness.

Sullivan, Nicole / Schorpp, Hannah / Crosky, Sarah / Thien, Scott / Helmer, Drew A / Litke, David R / Pigeon, Wilfred R / Quigley, Karen S / McAndrew, Lisa M

PloS one

2023 Volume 18, Issue 11, Page(s) e0295168

Abstract: Medically unexplained syndromes (MUS), also termed persistent physical symptoms, are both prevalent and disabling. Yet treatments for MUS are marked by high rates of patient dissatisfaction, as well as disagreement between patients and providers on the ... ...

Abstract	Medically unexplained syndromes (MUS), also termed persistent physical symptoms, are both prevalent and disabling. Yet treatments for MUS are marked by high rates of patient dissatisfaction, as well as disagreement between patients and providers on the management of persistent physical symptoms. A better understanding of patient-generated goals could increase collaborative goal setting and promote person-centered care, a critical component of MUS treatment; yet research in this area is lacking. This paper aimed to develop a typology of treatment and life goals among Gulf War veterans with a medically unexplained syndrome (Gulf War Illness). We examined participants' responses to open-ended questions about treatment and life goals using Braun and Clarke's thematic analysis methodology. Results showed that treatment goals could be categorized into four overarching themes: 1) Get better/healthier, 2) Improve quality of life, 3) Improve or seek additional treatment, and 4) Don't know/Don't have any. Life goals were categorized into six overarching themes: 1) Live a fulfilling life, 2) Live a happy life, 3) Live a healthy life, 4) Be productive/financially successful, 5) Manage GWI, and 6) Don't know/Don't have any. Treatment goals were largely focused on getting better/healthier (e.g., improving symptoms), whereas life goals focused on living a fulfilling life. Implications for the treatment of Gulf War Illness and patient-provider communication are discussed. ClinicalTrials.gov Identifier: NCT02161133.
MeSH term(s)	Humans ; Goals ; Gulf War ; Persian Gulf Syndrome/therapy ; Persian Gulf Syndrome/diagnosis ; Quality of Life ; Veterans
Language	English
Publishing date	2023-11-30
Publishing country	United States
Document type	Clinical Trial ; Journal Article
ZDB-ID	2267670-3
ISSN	1932-6203 ; 1932-6203
ISSN (online)	1932-6203
ISSN	1932-6203
DOI	10.1371/journal.pone.0295168
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Article ; Online: Phage-derived anti-idiotype and anti-YTE antibodies in development of MK-1654 pharmacokinetic and immune response assays.

Li, April / Swanson, Michael / Sullivan, Nicole / Homan, Ying / Nahas, Debbie / Mukhopadhyay, Shreya / Li, Hualin Helen / Cao, Yu / Xu, Weifeng / Tang, Huaping / Vora, Kalpit A / Chen, Zhifeng

Bioanalysis

2023 Volume 15, Issue 16, Page(s) 1049–1067

Abstract: Background: ...

Abstract	Background:
MeSH term(s)	Animals ; Humans ; Bacteriophages ; Antibodies, Neutralizing ; Antibodies, Monoclonal ; Immunity
Chemical Substances	MK-1654 ; Antibodies, Neutralizing ; Antibodies, Monoclonal
Language	English
Publishing date	2023-07-29
Publishing country	England
Document type	Journal Article
ISSN	1757-6199
ISSN (online)	1757-6199
DOI	10.4155/bio-2023-0081
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Article ; Online: Veteran Beliefs About the Causes of Gulf War Illness and Expectations for Improvement.

Kane, Naomi S / Hassabelnaby, Raghad / Sullivan, Nicole L / Graff, Fiona / Litke, David R / Quigley, Karen S / Pigeon, Wilfred R / Rath, Joseph F / Helmer, Drew A / McAndrew, Lisa M

International journal of behavioral medicine

2023 Volume 31, Issue 1, Page(s) 169–174

Abstract: Background: Individuals' beliefs about the etiology of persistent physical symptoms (PPS) are linked to differences in coping style. However, it is unclear which attributions are related to greater expectations for improvement.: Method and results: A ...

Abstract	Background: Individuals' beliefs about the etiology of persistent physical symptoms (PPS) are linked to differences in coping style. However, it is unclear which attributions are related to greater expectations for improvement. Method and results: A cross-sectional regression analysis (N = 262) indicated that Veterans with Gulf War Illness (GWI) who attributed their GWI to behavior, (e.g., diet and exercise), had greater expectations for improvement (p = .001) than those who attributed their GWI to deployment, physical, or psychological causes (p values > .05). Conclusions: Findings support the possible clinical utility of exploring perceived contributing factors of PPS, which may increase perceptions that improvement of PPS is possible. Trial registration: ClinicalTrials.gov Identifier: NCT02161133.
MeSH term(s)	Humans ; Veterans ; Persian Gulf Syndrome ; Cross-Sectional Studies ; Motivation ; Exercise
Language	English
Publishing date	2023-03-27
Publishing country	England
Document type	Journal Article
ZDB-ID	1187972-5
ISSN	1532-7558 ; 1070-5503
ISSN (online)	1532-7558
ISSN	1070-5503
DOI	10.1007/s12529-023-10166-1
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