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  1. Article ; Online: Spatial difference analysis and dynamic evolution prediction of urban industrial integrated water use efficiency in China

    Zhao Jingfeng / Sun Fan / Li Yan

    Heliyon, Vol 10, Iss 1, Pp e23797- (2024)

    1481  

    Abstract: Comprehensive quantitative assessment of China's urban industrial water use efficiency is effectively promote the green industrial development important steps in order to realize the overall development of high quality. Between 2009 and 2021, 290 in ... ...

    Abstract Comprehensive quantitative assessment of China's urban industrial water use efficiency is effectively promote the green industrial development important steps in order to realize the overall development of high quality. Between 2009 and 2021, 290 in China based on ground level above the panel data of the city, this paper conducts research based on two principles of efficiency improvement and four models of efficiency analysis. The results show that: First, from the perspective of spatial differences, the integrated water use efficiency of urban industry in China presents a slow and uneven upward trend of “low in the east and high in the west, high in the middle and low in the north and south”. Second, from the perspective of driving factors, population density and government public investment on the whole inhibit the development of this efficiency, while GDP development and technological innovation promote it. Third, from the perspective of dynamic evolution prediction, the phenomenon of “beggar-thy-neighbor” and “neighborly kindness” coexist. Therefore, the government should implement industrial water-saving measures according to local conditions, the society should improve the supervision of the behavior of wasting industrial water, and the enterprises should speed up the integration process of industrial primary and repeat water efficiency, so as to promote the comprehensive green transformation of the economy and society.
    Keywords Industrial comprehensive water use efficiency ; Green development ; Spatial difference ; Driving factors ; Dynamic evolution prediction ; Science (General) ; Q1-390 ; Social sciences (General) ; H1-99
    Subject code 710
    Language English
    Publishing date 2024-01-01T00:00:00Z
    Publisher Elsevier
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Article ; Online: A novel RyR2 mutation associated with co-morbid catecholaminergic polymorphic ventricular tachycardia (CPVT) and benign epilepsy with centrotemporal spikes (BECTS).

    Xing, Yinxue / Cui, Tao / Sun, Fan

    Journal of electrocardiology

    2024  Volume 84, Page(s) 75–80

    Abstract: In this case report, we describe a 14-year-old patient with a novel RyR2 gene mutation (c.6577G > T/p.Val2193Leu), identified through a comprehensive review of medical history, examination findings, and follow-up data. The pathogenic potential of this ... ...

    Abstract In this case report, we describe a 14-year-old patient with a novel RyR2 gene mutation (c.6577G > T/p.Val2193Leu), identified through a comprehensive review of medical history, examination findings, and follow-up data. The pathogenic potential of this mutation, which results in the loss of some interatomic forces and compromises the closure of the RyR2 protein pore leading to calcium leakage, was analyzed using the I-TASSER Suite to predict the structural changes in the protein. This mutation manifested clinically as co-morbid catecholaminergic polymorphic ventricular tachycardia (CPVT) and benign epilepsy with centrotemporal spikes (BECTS), a combination not previously documented in the same patient. While seizures were successfully managed with levetiracetam, the patient's exercise-induced syncope episodes could not be controlled with metoprolol, highlighting the complexity and challenge in managing CPVT associated with this novel RyR2 variation.
    Language English
    Publishing date 2024-03-28
    Publishing country United States
    Document type Journal Article
    ZDB-ID 410286-1
    ISSN 1532-8430 ; 0022-0736
    ISSN (online) 1532-8430
    ISSN 0022-0736
    DOI 10.1016/j.jelectrocard.2024.03.013
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: The initial experiences of junior nursing college students when communicating with children during pediatric clinical practicum: A phenomenological study.

    Chang, Li-Chuan / Chen, Chen-Jung / Chen, Chiu-I / Sun, Fan-Ko

    Journal of pediatric nursing

    2024  Volume 76, Page(s) e77–e84

    Abstract: Purpose: Nursing students feel stressed during pediatric clinical practicum due to limited communication encounters with hospitalized children. The purpose of this study was to describe junior nursing college students' experiences of communicating with ... ...

    Abstract Purpose: Nursing students feel stressed during pediatric clinical practicum due to limited communication encounters with hospitalized children. The purpose of this study was to describe junior nursing college students' experiences of communicating with children during pediatric clinical practicums.
    Design and methods: A qualitative phenomenological research design was used. Purposive sampling was used to recruit 18 junior nursing college students who completed their pediatric clinical practicum. Data were collected using semi-structured interviews and were analyzed using Colaizzi's seven-step method for data analysis.
    Results: Three themes emerged from the data. (1) Difficulties in communicating during initial practicum: fear, rejection, self-doubt of communication abilities, and unfamiliarity with the application of communication techniques posed frustrations among nursing students. (2) Efforts to learn during practicum: self-empowerment, seeking a diverse support system, adjusting communication methods, and striving to establish good relationships allowed nursing students to adapt to the pediatric curriculum. (3) Effective communication at the later stages of practicum: mastering fundamental communication techniques and exercising pediatric therapeutic communication techniques allowed nursing students to feel accomplished.
    Conclusions: Junior nursing college students initially encountered difficulties and frustration when communicating with children during their pediatric clinical practicum. This study serves as a guide for educators of pediatric nursing to design courses on communication with hospitalized children.
    Practice implications: These findings could be used to develop foundation courses on communicating with children for first-time pediatric nursing practicum students; for example, formulating a course on therapeutic play for children that encompasses communication techniques, pediatric ward simulation, and introduction to therapeutic play.
    MeSH term(s) Humans ; Female ; Students, Nursing/psychology ; Pediatric Nursing/education ; Male ; Qualitative Research ; Nurse-Patient Relations ; Child ; Education, Nursing, Baccalaureate ; Communication ; Adult ; Young Adult
    Language English
    Publishing date 2024-02-09
    Publishing country United States
    Document type Journal Article
    ZDB-ID 632731-x
    ISSN 1532-8449 ; 0882-5963
    ISSN (online) 1532-8449
    ISSN 0882-5963
    DOI 10.1016/j.pedn.2024.01.022
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Percutaneous lordoplasty for the treatment of severe osteoporotic vertebral compression fractures with kyphosis.

    Song, Tengfei / Sun, Fan / Liu, Shu / Ye, Tianwen

    Frontiers in neurology

    2023  Volume 14, Page(s) 1132919

    Abstract: Objective: The study aimed to explore the safety and effectiveness of percutaneous lordoplasty (PLP) in the treatment of severe osteoporotic vertebral compression fracture (OVCF).: Methods: Included in this prospective study were patients with single- ...

    Abstract Objective: The study aimed to explore the safety and effectiveness of percutaneous lordoplasty (PLP) in the treatment of severe osteoporotic vertebral compression fracture (OVCF).
    Methods: Included in this prospective study were patients with single-segment acute severe OVCF who were treated with PLP in our institution from July 2016 to October 2019. Patients' back pain and quality of life were assessed using the visual analog scale (VAS) and SF-36 scores. Lateral X-ray radiography of the spine was performed to measure the vertebral height, vertebral kyphotic angle, and segmental kyphotic angle, and to evaluate the outcome of fracture reduction and kyphotic correction. Intra-and postoperative complications were recorded.
    Results: Of the 51 included patients, 47 patients were followed up for 12 months. The VAS score decreased from preoperative 7.33 ± 1.92 to postoperative 1.76 ± 0.85 at the 12th month (
    Conclusion: PLP can well reduce the risk of fracture and achieve good kyphotic correction and may prove to be a safe, cost-effective and minimally invasive alternative option for the treatment of severe OVCF with kyphotic deformity.
    Language English
    Publishing date 2023-07-28
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2564214-5
    ISSN 1664-2295
    ISSN 1664-2295
    DOI 10.3389/fneur.2023.1132919
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Critical and distinct roles of cell type-specific NF-κB2 in lung cancer.

    Sun, Fan / Xiao, Yadong / Shapiro, Steven D / Qu, Zhaoxia / Xiao, Gutian

    JCI insight

    2024  Volume 9, Issue 4

    Abstract: Different from the well-studied canonical NF-κB member RelA, the role of the noncanonical NF-κB member NF-κB2 in solid tumors, and lung cancer in particular, is poorly understood. Here we report that in contrast to the tumor-promoting role of RelA, NF- ... ...

    Abstract Different from the well-studied canonical NF-κB member RelA, the role of the noncanonical NF-κB member NF-κB2 in solid tumors, and lung cancer in particular, is poorly understood. Here we report that in contrast to the tumor-promoting role of RelA, NF-κB2 intrinsic to lung epithelial and tumor cells had no marked effect on lung tumorigenesis and progression. On the other hand, NF-κB2 limited dendritic cell number and activation in the lung but protected lung macrophages and drove them to promote lung cancer through controlling activation of noncanonical and canonical NF-κB, respectively. NF-κB2 was also required for B cell maintenance and T cell activation. The antitumor activity of lymphocyte NF-κB2 was dominated by the protumor function of myeloid NF-κB2; thus, NF-κB2 has an overall tumor-promoting activity. These studies reveal a cell type-dependent role for NF-κB2 in lung cancer and help understand the complexity of NF-κB action and lung cancer pathogenesis for better design of NF-κB-targeted therapy against this deadliest cancer.
    MeSH term(s) Humans ; NF-kappa B/metabolism ; NF-kappa B p52 Subunit ; Lung Neoplasms
    Chemical Substances NF-kappa B ; NF-kappa B p52 Subunit
    Language English
    Publishing date 2024-02-22
    Publishing country United States
    Document type Journal Article
    ISSN 2379-3708
    ISSN (online) 2379-3708
    DOI 10.1172/jci.insight.164188
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Undergraduate nursing students' learning experiences using design thinking on a human development course: A phenomenological study.

    Yao, YuChun / Long, Ann / Tseng, Yun Shan / Chiang, Chun-Ying / Sun, Fan-Ko

    Nurse education in practice

    2024  Volume 75, Page(s) 103886

    Abstract: Aim: To explore nursing students' perceptions of their design thinking learning experiences on a human development course.: Background: Design thinking is a person-centered analytic and creative learning process that promotes higher order thinking ... ...

    Abstract Aim: To explore nursing students' perceptions of their design thinking learning experiences on a human development course.
    Background: Design thinking is a person-centered analytic and creative learning process that promotes higher order thinking skills rather than knowledge retention alone. Currently, this is the first study that has investigated the use of the design thinking process for nursing students on a human development course.
    Design: A phenomenological research design.
    Methods: The participants were first-year nursing students enrolled on a human development course at a Taiwanese university. In-depth, semi-structured interviews were conducted in 2022 and sufficiently high information power was obtained after 15 participants were interviewed. Data were systematically analysed, summarized and decoded using Colaizzi's seven analysis steps.
    Results: Three themes and twelve subthemes emerged from the data. (1) Challenges experienced with the design thinking learning process: participants experienced anxiety because of the unfamiliar assignments, and they found the assignments to be thought-consuming, time-consuming and energy-consuming, plus the students needed to adapt to working in teams with classmates. (2) Adjustment strategies employed by participants: participants highlighted the importance of teamwork during the design thinking learning process. They achieved consensus through communication and sought support from others to overcome challenges related to design thinking; however, they ultimately needed to engage in problem-solving by themselves. (3) Developing the diversity of academic capabilities: after the human development course, participants experienced enriched mindsets, cognitive abilities, problem-solving skills, interpersonal relationships and knowledge application.
    Conclusions: Design thinking provides creative teaching opportunities and encourages nursing students to engage in experimental and creative learning, which is a meaningful experience for them. Nurse educators could use the insights thus obtained to design a curriculum that sources design thinking as a learning process while facilitating the complexity and diversity of students' higher order thinking skills and not just repetitive learning.
    MeSH term(s) Humans ; Education, Nursing, Baccalaureate ; Students, Nursing/psychology ; Learning ; Curriculum ; Thinking
    Language English
    Publishing date 2024-01-10
    Publishing country Scotland
    Document type Journal Article
    ZDB-ID 2058575-5
    ISSN 1873-5223 ; 1471-5953
    ISSN (online) 1873-5223
    ISSN 1471-5953
    DOI 10.1016/j.nepr.2024.103886
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Book ; Online: FreDo

    Sun, Fan-Keng / Boning, Duane S.

    Frequency Domain-based Long-Term Time Series Forecasting

    2022  

    Abstract: The ability to forecast far into the future is highly beneficial to many applications, including but not limited to climatology, energy consumption, and logistics. However, due to noise or measurement error, it is questionable how far into the future one ...

    Abstract The ability to forecast far into the future is highly beneficial to many applications, including but not limited to climatology, energy consumption, and logistics. However, due to noise or measurement error, it is questionable how far into the future one can reasonably predict. In this paper, we first mathematically show that due to error accumulation, sophisticated models might not outperform baseline models for long-term forecasting. To demonstrate, we show that a non-parametric baseline model based on periodicity can actually achieve comparable performance to a state-of-the-art Transformer-based model on various datasets. We further propose FreDo, a frequency domain-based neural network model that is built on top of the baseline model to enhance its performance and which greatly outperforms the state-of-the-art model. Finally, we validate that the frequency domain is indeed better by comparing univariate models trained in the frequency v.s. time domain.
    Keywords Computer Science - Machine Learning ; Computer Science - Artificial Intelligence
    Subject code 006
    Publishing date 2022-05-24
    Publishing country us
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article ; Online: How Protein Labeling Applying

    Xinyu Bian / Sun Fan / Xu Zhixuan

    E3S Web of Conferences, Vol 290, p

    2021  Volume 01020

    Abstract: In recent years, biosensing has played an irreplaceable position in scientific fields as well as our daily lives. A biosensor is an instrument that is sensitive to biological substances and converts its concentration into electrical signals for detection. ...

    Abstract In recent years, biosensing has played an irreplaceable position in scientific fields as well as our daily lives. A biosensor is an instrument that is sensitive to biological substances and converts its concentration into electrical signals for detection. It is an analysis tool or system composed of immobilized biologically sensitive materials as identification elements, appropriate physical and chemical transducers and signal amplification devices, and it has the functions of both a receiver and a converter. Pregnancy test sticks, blood glucose testing, etc. in life are all potential biosensors. The main point of this paper is to introduce several main techniques of biosensing for better understanding, like ELISA, fusion proteins, fluorescent probe and others. In the future, the bright future for them is also worth looking forward to if more researches and experiments can be processed in this area, for example, in the detection and treatment of cancer, medical technology can be further improved.
    Keywords Environmental sciences ; GE1-350
    Language English
    Publishing date 2021-01-01T00:00:00Z
    Publisher EDP Sciences
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  9. Article ; Online: Multi-Object Detection in Security Screening Scene Based on Convolutional Neural Network.

    Sun, Fan / Zhang, Xiangfeng / Liu, Yunzhong / Jiang, Hong

    Sensors (Basel, Switzerland)

    2022  Volume 22, Issue 20

    Abstract: The technique for target detection based on a convolutional neural network has been widely implemented in the industry. However, the detection accuracy of X-ray images in security screening scenarios still requires improvement. This paper proposes a ... ...

    Abstract The technique for target detection based on a convolutional neural network has been widely implemented in the industry. However, the detection accuracy of X-ray images in security screening scenarios still requires improvement. This paper proposes a coupled multi-scale feature extraction and multi-scale attention architecture. We integrate this architecture into the Single Shot MultiBox Detector (SSD) algorithm and find that it can significantly improve the effectiveness of target detection. Firstly, ResNet is used as the backbone network to replace the original VGG network to improve the feature extraction capability of the convolutional neural network for images. Secondly, a multi-scale feature extraction (MSE) structure is designed to enrich the information contained in the multi-stage prediction feature layer. Finally, the multi-scale attention architecture (MSA) is fused onto the prediction feature layer to eliminate the redundant features' interference and extract effective contextual information. In addition, a combination of Adaptive-NMS and Soft-NMS is used to output the final prediction anchor boxes when performing non-maximum suppression. The results of the experiments show that the improved method improves the mean average precision (mAP) value by 7.4% compared to the original approach. New modules make detection much more accurate while keeping the detection speed the same.
    MeSH term(s) Image Processing, Computer-Assisted/methods ; Neural Networks, Computer ; Algorithms ; Plant Extracts
    Chemical Substances Plant Extracts
    Language English
    Publishing date 2022-10-15
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2052857-7
    ISSN 1424-8220 ; 1424-8220
    ISSN (online) 1424-8220
    ISSN 1424-8220
    DOI 10.3390/s22207836
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Comment on "CO

    Sun, Fan / Xing, Xueli / Hong, Hui

    Small (Weinheim an der Bergstrasse, Germany)

    2022  Volume 19, Issue 11, Page(s) e2203647

    Abstract: The previously published report by Wang et al. provides universal equations for evaluating the net ... ...

    Abstract The previously published report by Wang et al. provides universal equations for evaluating the net CO
    Language English
    Publishing date 2022-11-29
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2168935-0
    ISSN 1613-6829 ; 1613-6810
    ISSN (online) 1613-6829
    ISSN 1613-6810
    DOI 10.1002/smll.202203647
    Database MEDical Literature Analysis and Retrieval System OnLINE

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