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Article ; Online: From provider to professor: Supporting nurse practitioner faculty through NONPF's Faculty Institute.

Sun, Grace / Stanik-Hutt, Julie

Journal of the American Association of Nurse Practitioners

2023 Volume 35, Issue 9, Page(s) 590–597

Abstract: Abstract: Over the past 15 years, the number of practicing nurse practitioners (NPs) has increased exponentially. This growth has been sustained by an increase in the number of schools offering NP preparation. Experienced NPs have assumed faculty ... ...

Abstract	Abstract: Over the past 15 years, the number of practicing nurse practitioners (NPs) has increased exponentially. This growth has been sustained by an increase in the number of schools offering NP preparation. Experienced NPs have assumed faculty positions in these schools. Although educational curricula prepare NPs to deliver high-quality patient care, it does not prepare graduates for academic roles in teaching, dissemination of scholarship, or service leadership to advance the profession. To address these gaps in NP faculty preparation, faculty development resources specific to NP education are needed. The National Organization of Nurse Practitioner Faculties (NONPF) has stepped forward to fill this gap. The NONPF Faculty Institute was created in 2017, and it includes the annual Fall Conference, the Faculty Leadership Mentoring Program, the Webinar Series, and, most recently, the joint NPACE/NONPF New Faculty Development Program. This comprehensive focus on faculty development aligns with NONPF's mission to promote excellence in NP education and advance the NP role in health care. Programs in the NONPF Faculty Institute are specifically designed to address the distinct learning needs of NP faculty. They use "just in time" presentations and active learning strategies to provide NP faculty with easily accessible and targeted content and opportunities for direct application of new skills. The Institute's goal is to provide NP faculty opportunities to prepare themselves to meet the teaching, scholarship and service leadership expectations of academia, the learning needs of students, and advance the impact of NP practice on patient and health care system outcomes.
MeSH term(s)	Humans ; Faculty ; Curriculum ; Education, Nursing, Graduate ; Students ; Nurse Practitioners/education
Language	English
Publishing date	2023-09-01
Publishing country	United States
Document type	Journal Article
ZDB-ID	2716317-9
ISSN	2327-6924 ; 1745-7599 ; 2327-6886 ; 1041-2972
ISSN (online)	2327-6924 ; 1745-7599
ISSN	2327-6886 ; 1041-2972
DOI	10.1097/JXX.0000000000000934
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Article ; Online: The ChatGPT Storm and What Faculty Can Do.

Sun, Grace H / Hoelscher, Stephanie H

Nurse educator

2023 Volume 48, Issue 3, Page(s) 119–124

Abstract: Background: ChatGPT, an artificial intelligence-driven, pretrained, deep learning language model, can generate natural language text in response to a given query. Its rapid growth has led to concerns about ethical use in academia.: Problem: The ... ...

Abstract	Background: ChatGPT, an artificial intelligence-driven, pretrained, deep learning language model, can generate natural language text in response to a given query. Its rapid growth has led to concerns about ethical use in academia. Problem: The exponential rise in the popularity of ChatGPT, and concerns of academic integrity with its use, has raised concerns among faculty for how to best address this issue. Approach: Faculty should understand the potential benefits and limitations of ChatGPT and create assignments that emphasize self-reflection, critical thinking, problem solving, and independent learning. Students must be taught how to critically evaluate information and how to make informed decisions. Conclusions: ChatGPT has the potential to revolutionize nursing education. However, it is critical for faculty to be familiar with its capabilities and limitations in order to foster effective, yet ethical and responsible utilization, while preparing students for the dynamic, rapidly advancing technological landscape in nursing and health care.
MeSH term(s)	Humans ; Artificial Intelligence ; Nursing Education Research ; Education, Nursing ; Faculty, Nursing ; Students, Nursing
Language	English
Publishing date	2023-02-27
Publishing country	United States
Document type	Journal Article
ZDB-ID	1034267-9
ISSN	1538-9855 ; 0363-3624
ISSN (online)	1538-9855
ISSN	0363-3624
DOI	10.1097/NNE.0000000000001390
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Article ; Online: Limbic Keratoconjunctivitis Associated With Dupilumab Treatment in Atopic Dermatitis.

Lin, Robert Y / Sun, Grace

The journal of allergy and clinical immunology. In practice

2022 Volume 10, Issue 9, Page(s) 2450–2451

MeSH term(s)	Antibodies, Monoclonal, Humanized/therapeutic use ; Dermatitis, Atopic/drug therapy ; Humans ; Interleukin-13 ; Keratoconjunctivitis/drug therapy ; Treatment Outcome
Chemical Substances	Antibodies, Monoclonal, Humanized ; Interleukin-13 ; dupilumab (420K487FSG)
Language	English
Publishing date	2022-08-02
Publishing country	United States
Document type	Journal Article
ZDB-ID	2843237-X
ISSN	2213-2201 ; 2213-2198
ISSN (online)	2213-2201
ISSN	2213-2198
DOI	10.1016/j.jaip.2022.06.029
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Article ; Online: 'I Thought It Was My Diabetes': An Acute Presentation of Neuromyelitis Optica Spectrum Disorder.

Nicely, Preston / Sun, Grace / Gupta, Simran / Lawlor, Maxwell / Selvaraj, Vijairam

Rhode Island medical journal (2013)

2024 Volume 107, Issue 3, Page(s) 10–13

Abstract: Neuromyelitis Optica Spectrum Disorder (NMOSD) is an immune-mediated neuroinflammatory disease of the central nervous system. Patients typically present with sensory deficits, weakness, and incontinence. This is a case of a 43-year-old female with ... ...

Abstract	Neuromyelitis Optica Spectrum Disorder (NMOSD) is an immune-mediated neuroinflammatory disease of the central nervous system. Patients typically present with sensory deficits, weakness, and incontinence. This is a case of a 43-year-old female with diabetes mellitus admitted for acute onset leg weakness and stool incontinence. Spinal MRI imaging revealed transverse myelitis, and her lab work was significant for an anti-aquaporin 4 (AQP4) antibody titer of 1:2,560. Initial treatment consisted of a high-dose steroid taper and plasmapheresis. This unique case illustrates the importance in recognizing delayed presentations of rare neuroinflammatory conditions previously assumed to be a sequela of diabetic neuropathy.
MeSH term(s)	Female ; Humans ; Adult ; Neuromyelitis Optica/diagnosis ; Neuromyelitis Optica/diagnostic imaging ; Autoantibodies/therapeutic use ; Disease Progression ; Diabetes Mellitus ; Magnetic Resonance Imaging
Chemical Substances	Autoantibodies
Language	English
Publishing date	2024-03-01
Publishing country	United States
Document type	Case Reports ; Journal Article
ZDB-ID	419430-5
ISSN	2327-2228 ; 0363-7913
ISSN (online)	2327-2228
ISSN	0363-7913
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Book ; Online: Exploring The Contribution of Innate Immune Cells to Breast Cancer Immunotherapy

Sun, Grace / Patel, Sandip

2023

Abstract: Breast cancer is the leading type of cancer in women. About 10-15% of breast cancers are triple-negative breast cancer (TNBC), a subtype with the worst prognosis. Due to the lack of estrogen, progesterone and HER2 receptor expression, chemotherapies have ...

Abstract	Breast cancer is the leading type of cancer in women. About 10-15% of breast cancers are triple-negative breast cancer (TNBC), a subtype with the worst prognosis. Due to the lack of estrogen, progesterone and HER2 receptor expression, chemotherapies have been the standard of care for decades. Immunotherapy has emerged as promising for TNBC treatment. In 2020, the Food and Drug Administration (FDA) granted approval to pembrolizumab in combination with chemotherapy for patients with advanced triple-negative breast cancer. However, only a subgroup of advanced TNBC patients live longer whose tumors have a PD-L1 Combined Positive Score of at least 10 (CPS>=10). There is still an unmet medical need to provide alternative treatment for the rest of patients. Interestingly, a few of patients at UCSD Moores Cancer Center were found to have had excellent responses to pembrolizumab despite low CPS scores (termed Elite Responders). The hypothesis of this project is that there may be an alternative immune response mechanism and/or crosstalk happening between the innate and adaptive immune systems, especially in Natural Killer Cells and Macrophages, that contributed to this unexpected excellent response. Our procedure used ACDBio RNAscope Multiplex Fluorescence v2 method to spatially analyze innate immune cells (Natural Killer cells and macrophages) and adaptive immune cells (T-cells) in the Tumor Micro Environment. Our data demonstrated increased tumor infiltration of innate immune cells (macrophage and Natural Killer cells) in the Elite Responders. This conclusion indicated the joint effort of two immune systems (innate and adaptive) which eventually led to increased survival.
Keywords	Quantitative Biology - Cell Behavior
Subject code	616 ; 610
Publishing date	2023-07-06
Publishing country	us
Document type	Book ; Online
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Article ; Online: Oligomeric Amyloid-β and Tau Alter Cell Adhesion Properties and Induce Inflammatory Responses in Cerebral Endothelial Cells Through the RhoA/ROCK Pathway.

Hossen, Faruk / Geng, Xue / Sun, Grace Y / Yao, Xincheng / Lee, James C

Molecular neurobiology

2024

Abstract: Dysfunction of cerebral endothelial cells (CECs) has been implicated in the pathology of Alzheimer's disease (AD). Despite evidence showing cytotoxic effects of oligomeric amyloid-β (oAβ) and Tau (oTau) in the central nervous system, their direct effects ...

Abstract	Dysfunction of cerebral endothelial cells (CECs) has been implicated in the pathology of Alzheimer's disease (AD). Despite evidence showing cytotoxic effects of oligomeric amyloid-β (oAβ) and Tau (oTau) in the central nervous system, their direct effects on CECs have not been fully investigated. In this study, we examined the direct effects of oAβ, oTau, and their combination on cell adhesion properties and inflammatory responses in CECs. We found that both oAβ and oTau increased cell stiffness, as well as the p-selectin/Sialyl-Lewis
Language	English
Publishing date	2024-04-02
Publishing country	United States
Document type	Journal Article
ZDB-ID	645020-9
ISSN	1559-1182 ; 0893-7648
ISSN (online)	1559-1182
ISSN	0893-7648
DOI	10.1007/s12035-024-04138-z
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Zs.A 2411: Show issues

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Article: Gender-specific responses to multifaceted factors associated with disordered eating among adolescents of 7th to 9th grade.

Chen, Duan-Rung / Sun, Grace / Levin, Brianna

Journal of eating disorders

2022 Volume 10, Issue 1, Page(s) 5

Abstract: Background: The prevalence of disordered eating is increasing among adolescents in Asia. The prevalence and predictors of disordered eating in boys have often gone unrecognized. This study examined gender-specific responses to multifaceted factors ... ...

Abstract	Background: The prevalence of disordered eating is increasing among adolescents in Asia. The prevalence and predictors of disordered eating in boys have often gone unrecognized. This study examined gender-specific responses to multifaceted factors associated with disordered eating, including personal, behavioral, family, and school-related characteristics. Methods: After excluding responses with incomplete information, a sample of 729 adolescents (48.97% boys) between the ages of 13 and 16 were surveyed through convenience sampling from 37 classrooms in three junior high schools in New Taipei City of Taiwan were analyzed. The Eating Attitudes Test-26 questionnaire was used to identify disordered eating. Results: No difference in the prevalence of disordered eating between the genders was found. Adolescent girls exhibit a preoccupation with fatness and a desire to be thinner, whereas boys are more likely to engage in extreme dieting behaviors such as vomiting, keeping the stomach empty, and avoiding sweets. Girls engaging in disordered eating reported relatively high levels of interpersonal stress involving family member weight-teasing, low peer acceptance, and high peer pressure to control weight. High intensity of regular exercise was found in girls with disordered eating. The perception of body weight is a more critical factor of engaging in disordered eating for boys than girls. Adolescents with immigrant parents were associated with disordered eating among both genders. Conclusions: Changing gender-specific weight-related norms in schools and families is essential to reduce the prevalence of disordered eating, particularly among girls. Future studies using representative samples to confirm this study's findings are warranted.
Language	English
Publishing date	2022-01-10
Publishing country	England
Document type	Journal Article
ZDB-ID	2699357-0
ISSN	2050-2974
ISSN	2050-2974
DOI	10.1186/s40337-021-00524-3
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Article ; Online: Sex and Gender Reporting in Ophthalmology.

Aguwa, Ugochi T / Sun, Grace / Woreta, Fasika

JAMA ophthalmology

2022

Language	English
Publishing date	2022-10-20
Publishing country	United States
Document type	Journal Article
ZDB-ID	2701705-9
ISSN	2168-6173 ; 2168-6165
ISSN (online)	2168-6173
ISSN	2168-6165
DOI	10.1001/jamaophthalmol.2022.4255
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Article ; Online: Presence of Diversity or Inclusion Information on US Ophthalmology Residency Program Websites.

Ledesma Vicioso, Nahomy / Woreta, Fasika / Sun, Grace

JAMA ophthalmology

2022 Volume 140, Issue 6, Page(s) 606–609

Abstract: Importance: Groups historically underrepresented in medicine also remain underrepresented within ophthalmology. Prospective applicants, in particular women and racial and ethnic minority groups, consider program factors related to gender diversity, ... ...

Abstract	Importance: Groups historically underrepresented in medicine also remain underrepresented within ophthalmology. Prospective applicants, in particular women and racial and ethnic minority groups, consider program factors related to gender diversity, ethnic diversity, and program culture more than nonminority groups. A prospective applicant's decision to apply to a particular residency program may be influenced by the information presented on the program's website. Objective: To evaluate for presence of diversity or inclusion information on US ophthalmology program websites. Design, setting, and participants: This quality improvement study, conducted from May 1 to June 2, 2021, included a cross-sectional review of ophthalmology program websites. Ophthalmology program websites were reviewed for the presence of 6 predetermined diversity or inclusion information criteria. Main outcomes and measures: The presence of 6 predetermined diversity or inclusion information criteria. Association between program size and ranking with presence of diversity or inclusion information criteria was assessed. Results: Of the 121 US program websites reviewed, 29 (24%) met at least 1 of the 6 predetermined criteria. Programs with more than 12 residents (odds ratio [OR], 3.58; 95% CI, 1.39-9.55; P = .004) and programs ranked within the top 20 best hospitals for ophthalmology (OR, 3.28; 95% CI, 1.05-10.1; P = .02) were more likely to have at least 1 of the diversity or inclusion information criteria on their website. Conclusion and relevance: Results of this quality improvement study suggest that the majority of US ophthalmology residency programs do not have information regarding diversity or inclusion on their websites. Although this investigation cannot determine how an ophthalmology residency program's website reflects the diversity and inclusion within the program, these findings suggest that there is a gap in the information that prospective applicants can collect when evaluating ophthalmology residency program websites.
MeSH term(s)	Cross-Sectional Studies ; Ethnicity ; Female ; Humans ; Internship and Residency ; Minority Groups ; Ophthalmology/education ; Prospective Studies
Language	English
Publishing date	2022-05-12
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2701705-9
ISSN	2168-6173 ; 2168-6165
ISSN (online)	2168-6173
ISSN	2168-6165
DOI	10.1001/jamaophthalmol.2022.1326
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Article ; Online: Current and Emerging Therapeutic Targets for the Treatment of Cholangiocarcinoma: An Updated Review.

Hadfield, Matthew J / DeCarli, Kathryn / Bash, Kinan / Sun, Grace / Almhanna, Khaldoun

International journal of molecular sciences

2023 Volume 25, Issue 1

Abstract: Cholangiocarcinoma is a malignancy of the bile ducts that is often associated with late diagnosis, poor overall survival, and limited treatment options. The standard of care therapy for cholangiocarcinoma has been cytotoxic chemotherapy with modest ... ...

Abstract	Cholangiocarcinoma is a malignancy of the bile ducts that is often associated with late diagnosis, poor overall survival, and limited treatment options. The standard of care therapy for cholangiocarcinoma has been cytotoxic chemotherapy with modest improvements in overall survival with the addition of immune checkpoint inhibitors. The discovery of actionable mutations has led to the advent of targeted therapies against FGFR and IDH-1, which has expanded the treatment landscape for this patient population. Significant efforts have been made in the pre-clinical space to explore novel immunotherapeutic approaches, as well as antibody-drug conjugates. This review provides an overview of the current landscape of treatment options, as well as promising future therapeutic targets.
MeSH term(s)	Humans ; Cholangiocarcinoma/drug therapy ; Bile Ducts ; Immune Checkpoint Inhibitors ; Bile Duct Neoplasms/drug therapy ; Bile Ducts, Intrahepatic
Chemical Substances	Immune Checkpoint Inhibitors
Language	English
Publishing date	2023-12-30
Publishing country	Switzerland
Document type	Journal Article ; Review
ZDB-ID	2019364-6
ISSN	1422-0067 ; 1422-0067 ; 1661-6596
ISSN (online)	1422-0067
ISSN	1422-0067 ; 1661-6596
DOI	10.3390/ijms25010543
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