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Book ; Thesis: Quantitative validation of CFD simulations of blood flow in cerebral aneurysms

Sun, Qi

in-vitro and in-vivo investigations

(Schriftenreihe des Lehrstuhls für Bildverarbeitung ; 6)

2012

Author's details	Qi Sun
Series title	Schriftenreihe des Lehrstuhls für Bildverarbeitung ; 6
Collection
Keywords	Intrakranielles Aneurysma ; Hämodynamik ; Dreidimensionale Strömung ; Numerische Strömungssimulation ; Bildgebendes Verfahren
Subject	Bildgebendes Diagnoseverfahren ; Diagnostik ; Bilddiagnostik ; Bildgebende Methode ; Medical Imaging ; Medizinische Bildgebung ; Bildgebende Diagnostik ; Bildgebende Verfahren ; Imaging ; CFD ; Computational fluid dynamics ; Numerische Strömungsmechanik ; Strömungsmechanik ; Gehirnarterienaneurysma ; Hirnaneurysma ; Gehirnaneurysma
Language	English
Size	IV, 161 S. : Ill., graph. Darst.
Edition	1. Aufl.
Publisher	Sierke
Publishing place	Göttingen
Publishing country	Germany
Document type	Book ; Thesis
Thesis / German Habilitation thesis	Aachen, Techn. Hochsch., Diss., 2011
HBZ-ID	HT017203044
ISBN	978-3-86844-383-7 ; 3-86844-383-5
Database	Catalogue ZB MED Medicine, Health

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Shelf mark	Loan status	Location
2014 A 4320	available for loan (reading room)	Lesesaal EG

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Article ; Online: Cell signaling and epigenetic regulation of nicotine-induced carcinogenesis.

Sun, Qi / Jin, Chunyuan

Environmental pollution (Barking, Essex : 1987)

2024 Volume 345, Page(s) 123426

Abstract: Nicotine, a naturally occurring tobacco alkaloid responsible for tobacco addiction, has long been considered non-carcinogenic. However, emerging evidence suggests that nicotine may possess carcinogenic properties in mice and could be a potential ... ...

Abstract	Nicotine, a naturally occurring tobacco alkaloid responsible for tobacco addiction, has long been considered non-carcinogenic. However, emerging evidence suggests that nicotine may possess carcinogenic properties in mice and could be a potential carcinogen in humans. This review aims to summarize the potential molecular mechanisms underlying nicotine-induced carcinogenesis, with a specific focus on epigenetic regulation and the activation of nicotinic acetylcholine receptors (nAChRs) in addition to genotoxicity and excess reactive oxygen species (ROS). Additionally, we explore a novel hypothesis regarding nicotine's carcinogenicity involving the downregulation of stem-loop binding protein (SLBP), a critical regulator of canonical histone mRNA, and the polyadenylation of canonical histone mRNA. By shedding light on these mechanisms, this review underscores the need for further research to elucidate the carcinogenic potential of nicotine and its implications for human health.
MeSH term(s)	Humans ; Mice ; Animals ; Nicotine/toxicity ; Histones/metabolism ; Epigenesis, Genetic ; Receptors, Nicotinic/genetics ; Receptors, Nicotinic/metabolism ; Carcinogenesis/chemically induced ; Signal Transduction ; RNA, Messenger/metabolism
Chemical Substances	Nicotine (6M3C89ZY6R) ; Histones ; Receptors, Nicotinic ; RNA, Messenger
Language	English
Publishing date	2024-01-29
Publishing country	England
Document type	Journal Article ; Review
ZDB-ID	280652-6
ISSN	1873-6424 ; 0013-9327 ; 0269-7491
ISSN (online)	1873-6424
ISSN	0013-9327 ; 0269-7491
DOI	10.1016/j.envpol.2024.123426
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Leveraging Human Visual Perception for an Optimized Virtual Reality Experience.

Sun, Qi

IEEE computer graphics and applications

2021 Volume 41, Issue 6, Page(s) 164–170

Abstract: We explore perceptually motivated research through virtual reality (VR) with the human as an experimental medium. We track, study, and model our spatio-temporal gaze behaviors to understand cognitive responses. Furthermore, we leverage this knowledge to ... ...

Abstract	We explore perceptually motivated research through virtual reality (VR) with the human as an experimental medium. We track, study, and model our spatio-temporal gaze behaviors to understand cognitive responses. Furthermore, we leverage this knowledge to advance computer graphics techniques in VR with more efficient rendering, increased display comfort, and safer locomotion.
MeSH term(s)	Computer Graphics ; Humans ; Knowledge ; Virtual Reality ; Visual Perception
Language	English
Publishing date	2021-12-10
Publishing country	United States
Document type	Journal Article
ISSN	1558-1756
ISSN (online)	1558-1756
DOI	10.1109/MCG.2021.3113392
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Light-activated g-C

Da, Yifan / Sun, Qi / Zhang, Limin / Tian, Yang

Chemical communications (Cambridge, England)

2024 Volume 60, Issue 27, Page(s) 3685–3688

Abstract: A novel micro-photoelectrode with a selective molecular sieve was created ... ...

Abstract	A novel micro-photoelectrode with a selective molecular sieve was created for
MeSH term(s)	Animals ; Mice ; Oxygen ; Catalysis ; Porosity ; Brain
Chemical Substances	Oxygen (S88TT14065)
Language	English
Publishing date	2024-03-28
Publishing country	England
Document type	Journal Article
ZDB-ID	1472881-3
ISSN	1364-548X ; 1359-7345 ; 0009-241X
ISSN (online)	1364-548X
ISSN	1359-7345 ; 0009-241X
DOI	10.1039/d4cc00246f
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Time-Resolved Spectroscopy for Dynamic Investigation of Photoresponsive Metal-Organic Frameworks.

Xiao, Yejun / Sun, Qi / Leng, Jing / Jin, Shengye

The journal of physical chemistry letters

2024 Volume 15, Issue 12, Page(s) 3390–3403

Abstract: Photoresponsive MOFs with precise and adjustable reticular structures are attractive for light conversion applications. Uncovering the photoinduced carrier dynamics lays the essential foundation for the further development and optimization of the MOF ... ...

Abstract	Photoresponsive MOFs with precise and adjustable reticular structures are attractive for light conversion applications. Uncovering the photoinduced carrier dynamics lays the essential foundation for the further development and optimization of the MOF material. With the application of time-resolved spectroscopy, photophysical processes including excimer formation, energy transfer/migration, and charge transfer/separation have been widely investigated. However, the identification of distinct photophysical processes in real experimental MOF spectra still remains difficult due to the spectral and dynamic complexity of MOFs. In this Perspective, we summarize the typical spectral features of these photophysical processes and the related analysis methods for dynamic studies performed by time-resolved photoluminescence (TR-PL) and transient absorption (TA) spectroscopy. Based on the recent understanding of excited-state properties of photoresponsive MOFs and the discussion of challenges and future outlooks, this Perspective aims to provide convenience for MOF kinetic analysis and contribute to the further development of photoresponsive MOF material.
Language	English
Publishing date	2024-03-19
Publishing country	United States
Document type	Journal Article ; Review
ISSN	1948-7185
ISSN (online)	1948-7185
DOI	10.1021/acs.jpclett.4c00296
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Conflicts between short- and long-term experiences affect visual perception through modulating sensory or motor response systems: Evidence from Bayesian inference models.

Sun, Qi / Wang, Jing-Yi / Gong, Xiu-Mei

Cognition

2024 Volume 246, Page(s) 105768

Abstract: The independent effects of short- and long-term experiences on visual perception have been discussed for decades. However, no study has investigated whether and how these experiences simultaneously affect our visual perception. To address this question, ... ...

Abstract	The independent effects of short- and long-term experiences on visual perception have been discussed for decades. However, no study has investigated whether and how these experiences simultaneously affect our visual perception. To address this question, we asked participants to estimate their self-motion directions (i.e., headings) simulated from optic flow, in which a long-term experience learned in everyday life (i.e., straight-forward motion being more common than lateral motion) plays an important role. The headings were selected from three distributions that resembled a peak, a hill, and a flat line, creating different short-term experiences. Importantly, the proportions of headings deviating from the straight-forward motion gradually increased in the peak, hill, and flat distributions, leading to a greater conflict between long- and short-term experiences. The results showed that participants biased their heading estimates towards the straight-ahead direction and previously seen headings, which increased with the growing experience conflict. This suggests that both long- and short-term experiences simultaneously affect visual perception. Finally, we developed two Bayesian models (Model 1 vs. Model 2) based on two assumptions that the experience conflict altered the likelihood distribution of sensory representation or the motor response system. The results showed that both models accurately predicted participants' estimation biases. However, Model 1 predicted a higher variance of serial dependence compared to Model 2, while Model 2 predicted a higher variance of the bias towards the straight-ahead direction compared to Model 1. This suggests that the experience conflict can influence visual perception by affecting both sensory and motor response systems. Taken together, the current study systematically revealed the effects of long- and short-term experiences on visual perception and the underlying Bayesian processing mechanisms.
MeSH term(s)	Humans ; Motion Perception/physiology ; Bayes Theorem ; Visual Perception/physiology ; Learning ; Optic Flow
Language	English
Publishing date	2024-03-12
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	1499940-7
ISSN	1873-7838 ; 0010-0277
ISSN (online)	1873-7838
ISSN	0010-0277
DOI	10.1016/j.cognition.2024.105768
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Screening and characterization of an anti-inflammatory pectic polysaccharide from Cucurbita moschata Duch.

Huang, Linlin / Sun, Qi / Li, Quanhong / Li, Xin

International journal of biological macromolecules

2024 Volume 264, Issue Pt 1, Page(s) 130510

Abstract: Pectin polysaccharides have demonstrated diverse biological activities, however, the inflammatory potential of pectin polysaccharides extracted from Cucurbita moschata Duch remains unexplored. This study aims to extract, characterize and evaluate the ... ...

Abstract	Pectin polysaccharides have demonstrated diverse biological activities, however, the inflammatory potential of pectin polysaccharides extracted from Cucurbita moschata Duch remains unexplored. This study aims to extract, characterize and evaluate the effects of pumpkin pectin polysaccharide on lipopolysaccharide (LPS)-induced inflammatory response in RAW264.7 cells and dextran sulfate sodium (DSS)-induced colitis in mice, along with its underlying mechanism of action. Initially, we extracted three fractions of pectin polysaccharides from pumpkin and screened them for anti-inflammatory activity in LPS-induced macrophages, identifying CMDP-3a as the most potent anti-inflammatory fraction. Subsequently, CMDP-3a underwent comprehensive characterization through chromatography and spectroscopic analysis, revealing CMDP-3a as an RG-I-HG type pectin polysaccharide with →4)-α-D-GalpA-(1 → and →4)-α-D-GalpA-(1 → 2,4)-α-L-Rhap-(1 → as the main chain. Further, in the LPS-induced RAW264.7 cells model, treatment with CMDP-3a significantly down-regulated the mRNA expression of inducible nitric oxide synthase (iNOS), cyclooxygenase-2 (COX-2), and pro-inflammatory cytokines (IL-1β, TNF-α, and IL-6) by inhibiting the MAPK and NF-κB signaling pathways. Finally, in a mouse colitis model, CMDP-3a administration obviously inhibited DSS-induced pathological alterations and reduced inflammatory cytokine expressions in the colonic tissues by down-regulating the TLR4/NF-κB and MAPK pathways. These findings provide a molecular basis for the potential application of CMDP-3a in reducing inflammatory responses.
MeSH term(s)	Animals ; Mice ; Cucurbita ; NF-kappa B/metabolism ; Lipopolysaccharides/adverse effects ; Pectins/pharmacology ; Pectins/metabolism ; Anti-Inflammatory Agents/chemistry ; Polysaccharides/pharmacology ; Polysaccharides/therapeutic use ; Polysaccharides/chemistry ; Colitis/chemically induced ; Colitis/drug therapy ; Colitis/pathology ; Cytokines/metabolism ; Nitric Oxide Synthase Type II/metabolism ; Cyclooxygenase 2/metabolism
Chemical Substances	NF-kappa B ; Lipopolysaccharides ; Pectins (89NA02M4RX) ; Anti-Inflammatory Agents ; Polysaccharides ; Cytokines ; Nitric Oxide Synthase Type II (EC 1.14.13.39) ; Cyclooxygenase 2 (EC 1.14.99.1)
Language	English
Publishing date	2024-03-04
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	282732-3
ISSN	1879-0003 ; 0141-8130
ISSN (online)	1879-0003
ISSN	0141-8130
DOI	10.1016/j.ijbiomac.2024.130510
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Article ; Online: Exploring the thermal behavior of nitrocellulose used for lacquers by slow heating experiments

Sun, Qi / Qiu, Yue

Cellulose. 2023 Jan., v. 30, no. 1 p.427-447

2023

Abstract: This paper studied the spontaneous combustion risks of nitrocellulose used for lacquers by experimental and mathematical methods. The heat generation behavior and kinetic parameters of thermal decomposition of nitrocellulose in different nitrogen ... ...

Abstract	This paper studied the spontaneous combustion risks of nitrocellulose used for lacquers by experimental and mathematical methods. The heat generation behavior and kinetic parameters of thermal decomposition of nitrocellulose in different nitrogen contents and of different masses were analyzed, by heating samples with a microcalorimeter at heating rates of 0.5 °C min⁻¹ and lower under both air and inert atmosphere. The effects of heating rate and atmosphere on thermal behavior were identified. The iso-conversional models were used to calculate the kinetics. A critical conversion rate of 0.2–0.3 was identified for nitrocellulose in different contents. When the conversion rate was lower than the critical value, the activation energy increased slightly. After reaching the critical value, the activation energy continued to decrease. The activation energy at the initial decomposition stage was derived by a simplified kinetic algorithm. Based on Semenov model and Frank-Kamenetskii model, the critical ignition temperature and self-accelerating decomposition temperature of nitrocellulose in standard 25 kg, 100 kg and 150 kg packages were derived and compared to typical energetic materials. Nitrocellulose with a higher nitrogen content or in a larger package size had lower apparent activation energy and SADT. Values of SADT could be easily reached with external heat sources, indicating the potential thermal risks of nitrocellulose stored in large sizes under slow heating conditions.
Keywords	activation energy ; air ; algorithms ; cellulose ; combustion ; heat ; models ; nitrogen ; nitrogen content ; temperature ; thermal degradation ; thermal properties
Language	English
Dates of publication	2023-01
Size	p. 427-447.
Publishing place	Springer Netherlands
Document type	Article ; Online
ZDB-ID	1496831-9
ISSN	1572-882X ; 0969-0239
ISSN (online)	1572-882X
ISSN	0969-0239
DOI	10.1007/s10570-022-04903-0
Database	NAL-Catalogue (AGRICOLA)

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Article: Preparation and Strength Formation Mechanism of Calcined Oyster Shell, Red Mud, Slag, and Iron Tailing Composite Cemented Paste Backfill.

Lu, Hongxu / Sun, Qi

Materials (Basel, Switzerland)

2022 Volume 15, Issue 6

Abstract: The use of bulk solid-waste iron tailing (IOT), red mud (RM), and oyster shells to prepare cemented paste backfill (CPB) can effectively solve the ecological problems caused by industrial solid waste storage and improve the utilization rate of such ... ...

Abstract	The use of bulk solid-waste iron tailing (IOT), red mud (RM), and oyster shells to prepare cemented paste backfill (CPB) can effectively solve the ecological problems caused by industrial solid waste storage and improve the utilization rate of such materials. In this study, a new type of CPB was prepared by partially replacing slag with RM, with calcined oyster shell (COS) as the alkaline activator and IOT as aggregate. The central composite design (CCD) method was used to design experiments to predict the effects of the COS dosage, RM substitution rate, solid mass, and aggregate-binder ratio using 28-dUCS, slump, and the cost of CPB. In this way, a regression model was established. The quantum genetic algorithm (QGA) was used to optimize the regression model, and X-ray diffraction (XRD), Fourier transform infrared (FTIR), scanning electron microscope (SEM), and energy dispersive spectroscopy (EDS) microscopic tests are performed on CPB samples of different ages with the optimal mix ratio. The results showed that COS is a highly active alkaline substance that provides an alkaline environment for polymerization reactions. In the alkaline medium, the hematite and goethite in RM and quartz in IOT gradually dissolved and participated in the process of polymerization. The main polymerization products of the CPB samples are calcium-silicate-hydrogel (C-S-H), calcium-aluminosilicate-hydrogel (C-A-S-H), and aluminosilicate crystals such as quartz, albite, and foshagite. These products are intertwined and filled in the internal pores of the CPB, enabling the pore contents to decrease and the interiors of the CPB samples to gradually connect into a whole. In this way, the compressive strength is increased.
Language	English
Publishing date	2022-03-16
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2487261-1
ISSN	1996-1944
ISSN	1996-1944
DOI	10.3390/ma15062199
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Deciphering the effects of antibiotics on nitrogen removal and bacterial communities of autotrophic denitrification systems in a three-dimensional biofilm electrode reactor.

Sun, Qi / Zhu, Guangcan

Environmental pollution (Barking, Essex : 1987)

2022 Volume 315, Page(s) 120476

Abstract: In this study, three-dimensional biofilm electrode reactors (3D-BERs) were constructed, and the effects of metronidazole (MNZ) on the nitrogen removal performance and bacterial communities of autotrophic denitrification systems were evaluated. The ... ...

Abstract	In this study, three-dimensional biofilm electrode reactors (3D-BERs) were constructed, and the effects of metronidazole (MNZ) on the nitrogen removal performance and bacterial communities of autotrophic denitrification systems were evaluated. The results showed that nitrogen removal decreased slightly as the MNZ concentration increased. Specifically, nitrate-nitrogen removal efficiency decreased from 97.98% to 89.39%, 86.93%, 82.64%, and 82.77% within 12 h after the addition of 1, 3, 5, and 10 mg/L MNZ, respectively. The 3D-BERs showed excellent MNZ degradation ability, especially at a concentration of 10 mg/L. The MNZ removal efficiency could be as high as 94.38% within 6 h, and the average removal rate increased as the MNZ concentration increased. High-throughput sequencing results showed significant changes in the bacterial community under different MNZ concentrations. As the antibiotic concentration increased, the relative abundances of Hydrogenophaga and Silanimonas increased, from only 0.09% and 0.01% without antibiotics to 3.55% and 2.35%, respectively, at an antibiotic concentration of 10 mg/L. Changes in antibiotic concentration altered the abundances of genes involved in nitrogen metabolism. Redundancy analysis showed that MNZ removal efficiency was positively correlated with SBR1031, SC-I-84, Hydrogenophaga, Silanimonas and Denitratesoma, whereas the removal efficiencies of nitrate-nitrogen and total nitrogen were negatively correlated with these genera. The results of this study provide a theoretical basis for studying the toxic effects of antibiotics on the denitrification process and also provide guidance for the control of antibiotics and nitrogen pollution in ecosystems.
MeSH term(s)	Denitrification ; Nitrogen/metabolism ; Nitrates ; Bioreactors ; Anti-Bacterial Agents/toxicity ; Ecosystem ; Biofilms ; Bacteria/genetics ; Bacteria/metabolism ; Electrodes ; Waste Water
Chemical Substances	Nitrogen (N762921K75) ; Nitrates ; Anti-Bacterial Agents ; Waste Water
Language	English
Publishing date	2022-10-19
Publishing country	England
Document type	Journal Article
ZDB-ID	280652-6
ISSN	1873-6424 ; 0013-9327 ; 0269-7491
ISSN (online)	1873-6424
ISSN	0013-9327 ; 0269-7491
DOI	10.1016/j.envpol.2022.120476
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