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  1. Article: [SWOT analysis and strategy research for the training of doctoral candidate in general practice in China].

    Sun, Y J / Ren, J J

    Zhonghua yi xue za zhi

    2023  Volume 103, Issue 22, Page(s) 1662–1665

    Abstract: General practice has entered a stage of rapid development, but the doctoral postgraduate as the reserve strength of discipline development, its cultivation is still at the exploration stage. Through analyzing the internal strengths (S), internal weakness ...

    Abstract General practice has entered a stage of rapid development, but the doctoral postgraduate as the reserve strength of discipline development, its cultivation is still at the exploration stage. Through analyzing the internal strengths (S), internal weakness (W), external opportunities (O), and external threats (T) faced by the Ph.D. student in general practice in training, this paper discusses feasible strategies and plans for the cultivation of general practice to help the cultivation of high-level talents.
    MeSH term(s) Humans ; General Practice ; Students ; China ; Physicians
    Language Chinese
    Publishing date 2023-06-10
    Publishing country China
    Document type English Abstract ; Journal Article
    ZDB-ID 132513-9
    ISSN 0376-2491
    ISSN 0376-2491
    DOI 10.3760/cma.j.cn112137-20221220-02680
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.B 2011: Show issues Location:
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  2. Article: [Comparative study of ultrasound and magnetic resonance imaging in the diagnosis of asymptomatic anterosuperior acetabular labrum tears].

    Fu, Q / Gao, G Y / Xu, Y / Lin, Z H / Sun, Y J / Cui, L G

    Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences

    2023  Volume 55, Issue 4, Page(s) 665–669

    Abstract: Objective: To explore the diagnostic value of ultrasound for asymptomatic anterosuperior acetabular labral tears (ALT).: Methods: From August 2018 to February 2020, a total of 64 asymptomatic volunteers (101 hips) were recruited to complete 3.0T ... ...

    Abstract Objective: To explore the diagnostic value of ultrasound for asymptomatic anterosuperior acetabular labral tears (ALT).
    Methods: From August 2018 to February 2020, a total of 64 asymptomatic volunteers (101 hips) were recruited to complete 3.0T magnetic resonance imaging (MRI) and ultrasound examination. Among these asymptomatic volunteers, 31 were male and 33 were female, with the median age 35 (32, 39) years. Using 3.0T MRI findings as golden standard, the sensitivity, specificity, positive predictive value, negative predictive value and accuracy of ultrasound were calculated.
    Results: The results showed the presence of unilateral or bilateral ALT in 33 (51.56%) asymptomatic vo-lunteers with a total of 47 hips (46.53%). Of the 37 asymptomatic volunteers with bilateral hip MRI examination, 14 had bilateral ALT and 8 had unilateral ALT. Of the 27 asymptomatic volunteers who underwent unilateral hip MRI, 11 had ALT. Of the 33 asymptomatic volunteers with labral tears, 11 were male and 22 were female, with 30 right hips and 17 left hips. The median age was 36 (33, 40) years in the ALT group and 34 (32, 38) years in the non-ALT group. There was no significant difference in age between the two groups (
    Conclusion: The ALT are common findings in asymptomatic volunteers on MRI. Intra-labrum cleft and labral heterogeneous echogenicity are common ultrasonographic signs in asymptomatic volunteers with ALT. The labra were more swollen in the asymptomatic volunteers with ALT compared to those without ALT.
    MeSH term(s) Humans ; Male ; Female ; Adult ; Acetabulum/diagnostic imaging ; Hip Joint ; Hip Injuries/epidemiology ; Hip Injuries/pathology ; Magnetic Resonance Imaging/methods ; Ultrasonography ; Cartilage, Articular/diagnostic imaging ; Arthroscopy
    Language Chinese
    Publishing date 2023-08-01
    Publishing country China
    Document type English Abstract ; Journal Article
    ZDB-ID 2452593-5
    ISSN 1671-167X
    ISSN 1671-167X
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: [Intraductal carcinoma of parotid gland: a case report].

    Sun, Y J / Wang, Z X / Jiang, Z M

    Zhonghua er bi yan hou tou jing wai ke za zhi = Chinese journal of otorhinolaryngology head and neck surgery

    2021  Volume 56, Issue 10, Page(s) 1106–1108

    MeSH term(s) Carcinoma, Intraductal, Noninfiltrating ; Humans ; Parotid Gland ; Parotid Neoplasms
    Language Chinese
    Publishing date 2021-10-19
    Publishing country China
    Document type Case Reports ; Journal Article
    ZDB-ID 2195655-8
    ISSN 1673-0860
    ISSN 1673-0860
    DOI 10.3760/cma.j.cn115330-20210215-00065
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 3733: Show issues Location:
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  4. Article ; Online: Dietary Fiber and All-Cause and Cardiovascular Mortality in Older Adults with Hypertension: A Cohort Study Of NHANES.

    Zhang, H R / Yang, Y / Tian, W / Sun, Y J

    The journal of nutrition, health & aging

    2021  Volume 26, Issue 4, Page(s) 407–414

    Abstract: Objectives: Several studies have documented that dietary fiber was inversely associated with a variety of diseases, but the association of dietary fiber with the prognosis of older adults with hypertension is unknown. The aim was to assess the ... ...

    Abstract Objectives: Several studies have documented that dietary fiber was inversely associated with a variety of diseases, but the association of dietary fiber with the prognosis of older adults with hypertension is unknown. The aim was to assess the association of dietary fiber with all-cause and cardiovascular mortality in older adults with hypertension.
    Methods: This study enrolled 4906 participants (51.6% were female) aged 65 years or older with hypertension in the National Health and Nutrition Examination Survey (NHANES) 2003-2014 and ascertained mortality through December 31, 2015. Dietary fiber intake data were assessed by using a 24-h recall survey. Participants were grouped by dietary fiber intake quartiles: Q1(fiber < 10.20, g/day), Q2 (10.20 ≤ fiber < 14.45, g/day), Q3 (14.45 ≤ fiber < 19.85, g/day), and Q4 (19.85 ≤ fiber, g/day). Multivariate Cox proportional hazard models were used to evaluate the associations of dietary fiber intake with all-cause and cardiovascular mortality. Kaplan-Meier survival curves and restricted cubic spline models were applied to reveal the relationship between dietary fiber intake and mortality.
    Results: Over the median follow-up duration of 70 months (interquartile range: 38-100 months), 1369 participants were determined as all-cause mortality (27.9%) and 270 participants were identified as cardiovascular mortality (5.5%). In the fully adjusted model, the higher dietary fiber intake group was associated with relatively lower all-cause (Q4 vs Q1: 0.68 (0.58, 0.80); P for trend <0.001) and cardiovascular mortality (Q4 vs Q1: 0.64 (0.45, 0.92); P for trend =0.010). The non-linear relationship was not observed between dietary fiber intake and all-cause or cardiovascular mortality.
    Conclusions: Higher dietary fiber intake was significantly associated with decreased all-cause and cardiovascular mortality in older adults with hypertension. Increasing dietary fiber intake may improve the prognosis of older adults with hypertension.
    MeSH term(s) Aged ; Cardiovascular Diseases ; Cohort Studies ; Diet ; Dietary Fiber ; Female ; Humans ; Hypertension ; Male ; Nutrition Surveys
    Chemical Substances Dietary Fiber
    Language English
    Publishing date 2021-12-09
    Publishing country France
    Document type Journal Article
    ZDB-ID 2081921-3
    ISSN 1760-4788 ; 1279-7707
    ISSN (online) 1760-4788
    ISSN 1279-7707
    DOI 10.1007/s12603-022-1770-3
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: [Clinical analysis of penetrating keratoplasty for infants with congenital corneal opacity].

    Miao, S / Lin, Q / Sun, Y J / Song, Y W / Li, X / Pan, Z Q

    Zhonghua yan ke za zhi] Chinese journal of ophthalmology

    2022  Volume 58, Issue 6, Page(s) 426–432

    Abstract: Objective: ...

    Abstract Objective:
    MeSH term(s) Child ; Corneal Diseases/complications ; Corneal Diseases/surgery ; Corneal Neovascularization/complications ; Corneal Neovascularization/surgery ; Corneal Opacity/surgery ; Eye Abnormalities/surgery ; Follow-Up Studies ; Graft Survival ; Humans ; Infant ; Keratoplasty, Penetrating/adverse effects ; Keratoplasty, Penetrating/methods ; Retrospective Studies ; Treatment Outcome
    Language Chinese
    Publishing date 2022-06-13
    Publishing country China
    Document type Journal Article
    ZDB-ID 604574-1
    ISSN 0412-4081
    ISSN 0412-4081
    DOI 10.3760/cma.j.cn112142-20210729-00356
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.B 2482: Show issues Location:
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    Zs.MO 267: Show issues

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  6. Article: [Accuracy of photogrammetry and conventional impression techniques for complete-arch implant rehabilitation: an

    Sun, Y J / Ma, B W / Yue, X X / Lin, X / Geng, W

    Zhonghua kou qiang yi xue za zhi = Zhonghua kouqiang yixue zazhi = Chinese journal of stomatology

    2022  Volume 57, Issue 2, Page(s) 168–172

    Abstract: Objective: ...

    Abstract Objective:
    MeSH term(s) Aged ; Computer-Aided Design ; Dental Implants ; Dental Impression Materials ; Dental Impression Technique ; Humans ; Models, Dental ; Photogrammetry
    Chemical Substances Dental Implants ; Dental Impression Materials
    Language Chinese
    Publishing date 2022-02-13
    Publishing country China
    Document type Case Reports ; Journal Article
    ZDB-ID 1027950-7
    ISSN 1002-0098
    ISSN 1002-0098
    DOI 10.3760/cma.j.cn112144-20210407-00164
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: [Unilateral internal laryngocele: report of two cases].

    Sun, Y J / Tian, L L / Liu, J R / Zhang, J C / Ge, Jingchun

    Zhonghua er bi yan hou tou jing wai ke za zhi = Chinese journal of otorhinolaryngology head and neck surgery

    2022  Volume 57, Issue 8, Page(s) 1000–1002

    MeSH term(s) Humans ; Laryngeal Diseases/surgery ; Laryngocele/surgery ; Laryngoscopy
    Language Chinese
    Publishing date 2022-08-12
    Publishing country China
    Document type Case Reports ; Journal Article
    ZDB-ID 2195655-8
    ISSN 1673-0860
    ISSN 1673-0860
    DOI 10.3760/cma.j.cn115330-20211128-00765
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    Zs.A 3733: Show issues Location:
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  8. Article ; Online: Effects of miR-221 on the apoptosis of non-small cell lung cancer cells by lncRNA HOTAIR.

    Sun, Y-J / Li, J / Chen, C-H

    European review for medical and pharmacological sciences

    2019  Volume 23, Issue 10, Page(s) 4226–4233

    Abstract: Objective: The aim of this study was to investigate the effects of miR-221 on the proliferation of non-small cell lung cancer (NSCLC) cells through long non-coding RNA (lncRNA) HOX transcript antisense RNA (HO-TAIR), and to explore the possible ... ...

    Abstract Objective: The aim of this study was to investigate the effects of miR-221 on the proliferation of non-small cell lung cancer (NSCLC) cells through long non-coding RNA (lncRNA) HOX transcript antisense RNA (HO-TAIR), and to explore the possible underlying mechanism.
    Patients and methods: Reverse Transcription-Polymerase Chain Reaction (RT-PCR) was applied to detect the expression level of HOTAIR in 38 NSCLC patients. The correlations of HOTAIR expression with clinic-pathological features, as well as the correlation between HOTAIR expression and miR-221 expression was analyzed by RT-PCR. Furthermore, NSCLC cell lines were cultured in vitro, and the expressions of HOTAIR and miR-221 in NSCLC cells were also detected. A549 cells were transfected with miR-221 mimics, miR-221 inhibitors, HOTAIR-small interfering RNAs (siRNAs) and plasmid cytomegalovirus deoxyribonucleic acid (pcDNA)3.1-HOTAIR. The interaction between miR-221 and HOTAIR in transfected cells was analyzed via RT-PCR and Northern blotting. Ultimately, flow cytometry was adopted to analyze the effects of miR-221 on the apoptosis of NSCLC cells through HOTAIR.
    Results: The expression of HOTAIR in tissues of clinical patients only exhibited a correlation with the stage of cancer. The expressions of HOTAIR in patients with stage I and II were remarkably lower than those with stage III and IV. Additionally, the expression of HOTAIR was negatively correlated with the expression of miR-221 (r=-0.7651, p<0.0001). Further studies revealed that there was a negatively regulatory interaction between miR-221 expression and HOTAIR expression. Apoptosis assay results manifested that miR-221 significantly promoted the apoptosis of NSCLC cells by negatively regulating HOTAIR expression.
    Conclusions: MiR-221 promotes the apoptosis of NSCLC cells through negative regulation of lncRNA HOTAIR, which can be used in the treatment of NSCLC.
    MeSH term(s) A549 Cells/drug effects ; Apoptosis ; Carcinoma, Non-Small-Cell Lung/genetics ; Case-Control Studies ; Cell Line, Tumor ; Cell Proliferation ; China/epidemiology ; Female ; Gene Expression Regulation, Neoplastic ; Humans ; Lung Neoplasms/pathology ; Male ; MicroRNAs/genetics ; Middle Aged ; Neoplasm Staging/methods ; RNA, Long Noncoding/genetics ; RNA, Long Noncoding/metabolism ; RNA, Long Noncoding/pharmacology ; RNA, Small Interfering/metabolism ; Transfection/methods
    Chemical Substances HOTAIR long untranslated RNA, human ; MIRN221 microRNA, human ; MicroRNAs ; RNA, Long Noncoding ; RNA, Small Interfering
    Language English
    Publishing date 2019-06-07
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 605550-3
    ISSN 2284-0729 ; 1128-3602 ; 0392-291X
    ISSN (online) 2284-0729
    ISSN 1128-3602 ; 0392-291X
    DOI 10.26355/eurrev_201905_17927
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1887: Show issues Location:
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  9. Article ; Online: Overexpression of lncRNA GAS5 attenuates cardiac fibrosis through regulating PTEN/MMP-2 signal pathway in mice.

    Liu, H-L / Chen, C-H / Sun, Y-J

    European review for medical and pharmacological sciences

    2019  Volume 23, Issue 10, Page(s) 4414–4418

    Abstract: Objective: The present study aimed at investigating the effect and mechanism of lncRNA Growth Arrest-Specific 5 (GAS5) in cardiac fibrosis induced by isoproterenol (ISO) in vivo.: Materials and methods: The C57BL/6 mice were injected subcutaneously ... ...

    Abstract Objective: The present study aimed at investigating the effect and mechanism of lncRNA Growth Arrest-Specific 5 (GAS5) in cardiac fibrosis induced by isoproterenol (ISO) in vivo.
    Materials and methods: The C57BL/6 mice were injected subcutaneously with ISO to induce cardiac fibrosis and injected intracoronary with lentivirus pcDNA-GAS5. After 3 weeks, cardiac function was detected by echocardiography. The interstitial collagen volume was stained by Masson trichrome. The expression of GAS5 was measured by Reverse Transcriptase-Polymerase Chain Reaction (RT-PCR). The expressions of phosphatase and tensin homologue (PTEN), matrix metalloprotease-2 (MMP-2), α-smooth muscle actin (α-SMA), and collagen I protein were measured by Western blot.
    Results: Our results indicated that the expression of GAS5 was significantly down-regulated in the fibrotic myocardium. Overexpression of GAS5 after injection with pcDNA-GAS5 could attenuate cardiac fibrosis and improve cardiac function through increasing the expression of PTEN and decreasing the expression of MMP-2, α-SMA, and collagen I.
    Conclusions: Overexpression of GAS5 could attenuate cardiac fibrosis induced by ISO. The molecular mechanism was associated with the regulation of PTEN/MMP-2 signaling pathway.
    MeSH term(s) Actins/genetics ; Adrenergic beta-Antagonists ; Animals ; Collagen Type I/genetics ; Echocardiography ; Fibrosis ; Heart Diseases/chemically induced ; Heart Diseases/genetics ; Heart Diseases/pathology ; Isoproterenol ; Male ; Matrix Metalloproteinase 2/genetics ; Mice ; Mice, Inbred C57BL ; Myocardium/pathology ; PTEN Phosphohydrolase/genetics ; RNA, Long Noncoding/biosynthesis ; RNA, Long Noncoding/genetics ; Signal Transduction
    Chemical Substances Acta2 protein, mouse ; Actins ; Adrenergic beta-Antagonists ; Collagen Type I ; RNA, Long Noncoding ; PTEN Phosphohydrolase (EC 3.1.3.67) ; Pten protein, mouse (EC 3.1.3.67) ; Matrix Metalloproteinase 2 (EC 3.4.24.24) ; Mmp2 protein, mouse (EC 3.4.24.24) ; Isoproterenol (L628TT009W)
    Language English
    Publishing date 2019-06-06
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 605550-3
    ISSN 2284-0729 ; 1128-3602 ; 0392-291X
    ISSN (online) 2284-0729
    ISSN 1128-3602 ; 0392-291X
    DOI 10.26355/eurrev_201905_17949
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: [Efficacy of emergent systemic-pulmonary arterial anastomosis (Potts shunt) in a child with severe idiopathic pulmonary hypertension].

    Zhang, H / Peng, Y X / Sun, Y J / Xu, Z M / Bai, J

    Zhonghua xin xue guan bing za zhi

    2021  Volume 49, Issue 6, Page(s) 621–623

    MeSH term(s) Anastomosis, Surgical ; Child ; Familial Primary Pulmonary Hypertension ; Humans ; Hypertension, Pulmonary/surgery ; Pulmonary Arterial Hypertension ; Pulmonary Artery/surgery
    Language Chinese
    Publishing date 2021-04-07
    Publishing country China
    Document type Journal Article
    ZDB-ID 603425-1
    ISSN 0253-3758
    ISSN 0253-3758
    DOI 10.3760/cma.j.cn112148-20200803-00612
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