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  1. Article: Patient-Specific 3D-Printed Models in Pediatric Congenital Heart Disease.

    Sun, Zhonghua

    Children (Basel, Switzerland)

    2023  Volume 10, Issue 2

    Abstract: Three-dimensional (3D) printing technology has become increasingly used in the medical field, with reports demonstrating its superior advantages in both educational and clinical value when compared with standard image visualizations or current diagnostic ...

    Abstract Three-dimensional (3D) printing technology has become increasingly used in the medical field, with reports demonstrating its superior advantages in both educational and clinical value when compared with standard image visualizations or current diagnostic approaches. Patient-specific or personalized 3D printed models serve as a valuable tool in cardiovascular disease because of the difficulty associated with comprehending cardiovascular anatomy and pathology on 2D flat screens. Additionally, the added value of using 3D-printed models is especially apparent in congenital heart disease (CHD), due to its wide spectrum of anomalies and its complexity. This review provides an overview of 3D-printed models in pediatric CHD, with a focus on educational value for medical students or graduates, clinical applications such as pre-operative planning and simulation of congenital heart surgical procedures, and communication between physicians and patients/parents of patients and between colleagues in the diagnosis and treatment of CHD. Limitations and perspectives on future research directions for the application of 3D printing technology into pediatric cardiology practice are highlighted.
    Language English
    Publishing date 2023-02-07
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2732685-8
    ISSN 2227-9067
    ISSN 2227-9067
    DOI 10.3390/children10020319
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Logic-Based Fixed-Time Control for Uncertain Nonlinear Systems With Unknown Control Directions.

    Sun, Zhonghua / Hua, Changchun

    IEEE transactions on cybernetics

    2024  Volume PP

    Abstract: The fixed-time control problem is investigated for a class of uncertain nonlinear systems subjected to multiple unknown control directions. The control coefficients of nonlinear systems under consideration are time varying and their signs are not ... ...

    Abstract The fixed-time control problem is investigated for a class of uncertain nonlinear systems subjected to multiple unknown control directions. The control coefficients of nonlinear systems under consideration are time varying and their signs are not required to be identical. To tackle this challenge, a switching mechanism along with a novel dynamic boundary function is proposed. Utilizing the devised dynamic boundary function, adaptive parameters are introduced into the controller to effectively handle system uncertainties. It is proved that the system output converges to a small neighborhood of the origin in fixed time and the boundedness of all system signals is maintained. Finally, two simulation examples are used to show the validity of the presented switching control strategy.
    Language English
    Publishing date 2024-04-17
    Publishing country United States
    Document type Journal Article
    ISSN 2168-2275
    ISSN (online) 2168-2275
    DOI 10.1109/TCYB.2024.3380008
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Chest CT Imaging in the Diagnosis of COVID-19: Rapid Publications are not Equal to Quality of Research.

    Sun, Zhonghua

    Current medical imaging

    2021  Volume 17, Issue 4, Page(s) 447–451

    MeSH term(s) COVID-19 ; Humans ; SARS-CoV-2 ; Thorax ; Tomography, X-Ray Computed
    Language English
    Publishing date 2021-06-01
    Publishing country United Arab Emirates
    Document type Editorial ; Comment
    ISSN 1573-4056
    ISSN (online) 1573-4056
    DOI 10.2174/157340561704210419121707
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: 3D Printing in Medical Applications.

    Sun, Zhonghua

    Current medical imaging

    2021  Volume 17, Issue 7, Page(s) 811–813

    MeSH term(s) Printing, Three-Dimensional
    Language English
    Publishing date 2021-08-20
    Publishing country United Arab Emirates
    Document type Editorial
    ISSN 1573-4056
    ISSN (online) 1573-4056
    DOI 10.2174/157340561707210702114259
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Digital Variance Angiography: A Promising Alternative Technology to Traditional Angiography for Improvement of Image Quality with Reduction of Radiation and Contrast Medium Doses.

    Sun, Zhonghua

    Cardiovascular and interventional radiology

    2021  Volume 44, Issue 3, Page(s) 460–461

    MeSH term(s) Angiography ; Contrast Media ; Humans ; Technology
    Chemical Substances Contrast Media
    Language English
    Publishing date 2021-01-03
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 603082-8
    ISSN 1432-086X ; 0342-7196 ; 0174-1551
    ISSN (online) 1432-086X
    ISSN 0342-7196 ; 0174-1551
    DOI 10.1007/s00270-020-02739-4
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Use of Three-dimensional Printing in the Development of Optimal Cardiac CT Scanning Protocols.

    Sun, Zhonghua

    Current medical imaging

    2020  Volume 16, Issue 8, Page(s) 967–977

    Abstract: Three-dimensional (3D) printing is increasingly used in medical applications with most of the studies focusing on its applications in medical education and training, pre-surgical planning and simulation, and doctor-patient communication. An emerging area ...

    Abstract Three-dimensional (3D) printing is increasingly used in medical applications with most of the studies focusing on its applications in medical education and training, pre-surgical planning and simulation, and doctor-patient communication. An emerging area of utilising 3D printed models lies in the development of cardiac computed tomography (CT) protocols for visualisation and detection of cardiovascular disease. Specifically, 3D printed heart and cardiovascular models have shown potential value in the evaluation of coronary plaques and coronary stents, aortic diseases and detection of pulmonary embolism. This review article provides an overview of the clinical value of 3D printed models in these areas with regard to the development of optimal CT scanning protocols for both diagnostic evaluation of cardiovascular disease and reduction of radiation dose. The expected outcomes are to encourage further research towards this direction.
    MeSH term(s) Heart ; Humans ; Models, Cardiovascular ; Printing, Three-Dimensional ; Review Literature as Topic ; Tomography ; Tomography, X-Ray Computed
    Language English
    Publishing date 2020-02-28
    Publishing country United Arab Emirates
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ISSN 1573-4056
    ISSN (online) 1573-4056
    DOI 10.2174/1573405616666200124124140
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: 3D Printed Coronary Models Offer Potential Value in Visualising Coronary Anatomy and Coronary Stents for Investigation of Coronary CT Protocols.

    Sun, Zhonghua

    Current medical imaging

    2020  Volume 16, Issue 6, Page(s) 625–628

    Language English
    Publishing date 2020-08-10
    Publishing country United Arab Emirates
    Document type Editorial
    ISSN 1573-4056
    ISSN (online) 1573-4056
    DOI 10.2174/157340561606200523215058
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Diagnostic Value of Chest CT in Coronavirus Disease 2019 (COVID-19).

    Sun, Zhonghua

    Current medical imaging

    2020  Volume 16, Issue 4, Page(s) 274–275

    MeSH term(s) Betacoronavirus ; COVID-19 ; China ; Coronavirus ; Coronavirus Infections ; Humans ; Pandemics ; Pneumonia, Viral ; SARS-CoV-2 ; Tomography, X-Ray Computed
    Keywords covid19
    Language English
    Publishing date 2020-03-20
    Publishing country United Arab Emirates
    Document type Editorial ; Comment
    ISSN 1573-4056
    ISSN (online) 1573-4056
    DOI 10.2174/1573405616999200320163751
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Clinical Applications of Patient-Specific 3D Printed Models in Cardiovascular Disease: Current Status and Future Directions.

    Sun, Zhonghua

    Biomolecules

    2020  Volume 10, Issue 11

    Abstract: Three-dimensional (3D) printing has been increasingly used in medicine with applications in many different fields ranging from orthopaedics and tumours to cardiovascular disease. Realistic 3D models can be printed with different materials to replicate ... ...

    Abstract Three-dimensional (3D) printing has been increasingly used in medicine with applications in many different fields ranging from orthopaedics and tumours to cardiovascular disease. Realistic 3D models can be printed with different materials to replicate anatomical structures and pathologies with high accuracy. 3D printed models generated from medical imaging data acquired with computed tomography, magnetic resonance imaging or ultrasound augment the understanding of complex anatomy and pathology, assist preoperative planning and simulate surgical or interventional procedures to achieve precision medicine for improvement of treatment outcomes, train young or junior doctors to gain their confidence in patient management and provide medical education to medical students or healthcare professionals as an effective training tool. This article provides an overview of patient-specific 3D printed models with a focus on the applications in cardiovascular disease including: 3D printed models in congenital heart disease, coronary artery disease, pulmonary embolism, aortic aneurysm and aortic dissection, and aortic valvular disease. Clinical value of the patient-specific 3D printed models in these areas is presented based on the current literature, while limitations and future research in 3D printing including bioprinting of cardiovascular disease are highlighted.
    MeSH term(s) Bioprinting ; Cardiovascular Diseases/diagnostic imaging ; Cardiovascular Diseases/pathology ; Humans ; Imaging, Three-Dimensional/methods ; Magnetic Resonance Imaging ; Printing, Three-Dimensional ; Tomography, X-Ray Computed
    Language English
    Publishing date 2020-11-20
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2701262-1
    ISSN 2218-273X ; 2218-273X
    ISSN (online) 2218-273X
    ISSN 2218-273X
    DOI 10.3390/biom10111577
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Coronary computed tomography angiography assessment of relationship between right coronary artery-aorta angle and the development of coronary artery disease.

    Geerlings-Batt, Jade / Sun, Zhonghua

    Quantitative imaging in medicine and surgery

    2023  Volume 13, Issue 3, Page(s) 1948–1956

    Abstract: Whilst a correlation has been established between wide left main coronary artery bifurcation [left anterior descending-left circumflex (LAD-LCx)] angle (>80°) and the development of coronary artery disease (CAD), this retrospective, causal-comparative ... ...

    Abstract Whilst a correlation has been established between wide left main coronary artery bifurcation [left anterior descending-left circumflex (LAD-LCx)] angle (>80°) and the development of coronary artery disease (CAD), this retrospective, causal-comparative pilot study aimed to explore whether a relationship exists between right coronary artery (RCA)-aorta angle and CAD. Thirty normal cases were identified via radiology reports and selected as the control group with coronary computed tomography angiography (CCTA) scans performed on a 320-slice computed tomography (CT) scanner. Thirty CAD cases were selected with invasive coronary angiography performed to confirm the degree of stenosis, and CCTA performed on dual source and 320-slice CT scanners. An independent sample
    Language English
    Publishing date 2023-02-03
    Publishing country China
    Document type Journal Article
    ZDB-ID 2653586-5
    ISSN 2223-4306 ; 2223-4292
    ISSN (online) 2223-4306
    ISSN 2223-4292
    DOI 10.21037/qims-22-655
    Database MEDical Literature Analysis and Retrieval System OnLINE

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