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  1. Article ; Online: Indications for commencing aspirin for the prevention of pregnancy-induced hypertension and pre-eclampsia spectrum disorders.

    Pathiraja, P D M / Alrub, Nada Abu / Sunanda, Gargeswari

    Australian journal of general practice

    2022  Volume 51, Issue 10, Page(s) 767–768

    MeSH term(s) Aspirin/therapeutic use ; Female ; Humans ; Hypertension, Pregnancy-Induced/drug therapy ; Hypertension, Pregnancy-Induced/prevention & control ; Pre-Eclampsia/prevention & control ; Pregnancy
    Chemical Substances Aspirin (R16CO5Y76E)
    Language English
    Publishing date 2022-10-02
    Publishing country Australia
    Document type Journal Article
    ZDB-ID 2924889-9
    ISSN 2208-7958 ; 2208-794X
    ISSN (online) 2208-7958
    ISSN 2208-794X
    DOI 10.31128/AJGP-01-22-6289
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: The prevalence and significance of gestational cannabis use at an Australian tertiary hospital.

    Dunn, Mikaela L / Bradley, Clare / Ayonrinde, Oyedeji A / Van Rooyen, Derrick M / Tait, Robert J / White, Scott W / Fisher, Petrovia / Sunanda, Gargeswari / Mehta, Shailender / Ayonrinde, Oyekoya T

    The Australian & New Zealand journal of obstetrics & gynaecology

    2022  Volume 63, Issue 1, Page(s) 6–12

    Abstract: Background: Cannabis is one of the most common non-prescribed psychoactive substances used in pregnancy. The prevalence of gestational cannabis use is increasing.: Aim: The aim was to examine the prevalence of gestational cannabis use and associated ... ...

    Abstract Background: Cannabis is one of the most common non-prescribed psychoactive substances used in pregnancy. The prevalence of gestational cannabis use is increasing.
    Aim: The aim was to examine the prevalence of gestational cannabis use and associated pregnancy and neonate outcomes.
    Materials and methods: A retrospective observational study involving pregnant women delivering in 2019 was conducted at a tertiary hospital in Perth, Western Australia. Gestational cannabis and other substance use records were based on maternal self-report. Pregnancy outcomes included neonatal gestational age, birthweight, birth length, head circumference, resuscitation measures, special care nursery admission, 5-min Apgar score and initial neonatal feeding method.
    Results: Among 3104 pregnant women (mean age: 31 years), gestational cannabis use was reported by 1.6% (n = 50). Cannabis users were younger, more likely to use other substances and experience mental illness or domestic violence compared with non-users. Neonates born to cannabis users had a lower mean gestational age, birthweight and birth length compared to those born to non-cannabis users. Gestational cannabis use (odds ratio (OR) 3.3, 95% confidence interval (CI) 1.6-6.7) and tobacco smoking (OR 2.2, 95% CI 1.5-3.6) were associated with increased odds of a low-birthweight neonate. Combined cannabis and tobacco use during pregnancy further increased the likelihood of low birthweight (LBW, adjusted OR 3.9, 95% CI 1.6-9.3). Multivariate logistic regression analysis adjusted for maternal sociodemographical characteristics, mental illness, alcohol, tobacco and other substance use demonstrated gestational cannabis use to be independently associated with LBW (OR 2.3, 95% CI 1.1-5.2).
    Conclusion: Gestational cannabis use was independently associated with low birthweight, synergistically affected by tobacco smoking.
    MeSH term(s) Infant, Newborn ; Pregnancy ; Female ; Humans ; Adult ; Birth Weight ; Cannabis/adverse effects ; Prevalence ; Tertiary Care Centers ; Australia/epidemiology ; Pregnancy Outcome/epidemiology ; Substance-Related Disorders
    Language English
    Publishing date 2022-07-18
    Publishing country Australia
    Document type Observational Study ; Journal Article
    ZDB-ID 390815-x
    ISSN 1479-828X ; 0004-8666
    ISSN (online) 1479-828X
    ISSN 0004-8666
    DOI 10.1111/ajo.13589
    Database MEDical Literature Analysis and Retrieval System OnLINE

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