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Article ; Online: Histone editing elucidates the functional roles of H3K27 methylation and acetylation in mammals.

Sankar, Aditya / Mohammad, Faizaan / Sundaramurthy, Arun Kumar / Wang, Hua / Lerdrup, Mads / Tatar, Tulin / Helin, Kristian

Nature genetics

2022  Volume 54, Issue 6, Page(s) 754–760

Abstract: Posttranslational modifications of histones (PTMs) are associated with specific chromatin and gene expression ... ...

Abstract Posttranslational modifications of histones (PTMs) are associated with specific chromatin and gene expression states
MeSH term(s) Acetylation ; Animals ; Chromatin/genetics ; Chromatin/metabolism ; Drosophila melanogaster/genetics ; Histones/genetics ; Histones/metabolism ; Mammals/genetics ; Methylation ; Mice ; Polycomb Repressive Complex 2/genetics ; Protein Processing, Post-Translational/genetics
Chemical Substances Chromatin ; Histones ; Polycomb Repressive Complex 2 (EC 2.1.1.43)
Language English
Publishing date 2022-06-06
Publishing country United States
Document type Journal Article ; Research Support, Non-U.S. Gov't ; Research Support, N.I.H., Extramural
ZDB-ID 1108734-1
ISSN 1546-1718 ; 1061-4036
ISSN (online) 1546-1718
ISSN 1061-4036
DOI 10.1038/s41588-022-01091-2
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