Artikel ; Online: An efficient Sn(ii)-catalyzed one-pot synthesis of a 3-substituted azetidine-2,4-dione framework.
Organic & biomolecular chemistry
2017 Band 15, Heft 11, Seite(n) 2385–2391
Abstract: A novel Sn(ii)-catalyzed tandem cyclization reaction of aromatic aldehydes with ethyl cyanoacetate has been achieved to afford a series of 3-substituted azetidine-2,4-diones in good to excellent yields. This protocol provides straightforward access to ... ...
| Abstract | A novel Sn(ii)-catalyzed tandem cyclization reaction of aromatic aldehydes with ethyl cyanoacetate has been achieved to afford a series of 3-substituted azetidine-2,4-diones in good to excellent yields. This protocol provides straightforward access to construct the azetidine core through sequential Knoevenagel condensation, hydration and the C-N cyclization reaction. |
|---|---|
| Sprache | Englisch |
| Erscheinungsdatum | 2017-03-21 |
| Erscheinungsland | England |
| Dokumenttyp | Journal Article |
| ZDB-ID | 2097583-1 |
| ISSN | 1477-0539 ; 1477-0520 |
| ISSN (online) | 1477-0539 |
| ISSN | 1477-0520 |
| DOI | 10.1039/c7ob00294g |
| Datenquelle | MEDical Literature Analysis and Retrieval System OnLINE |
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