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  1. Article ; Online: An in silico study of the effects of cardiovascular aging on carotid flow waveforms and indexes in a virtual population.

    Suriani, Irene / Bouwman, R Arthur / Mischi, Massimo / Lau, Kevin D

    American journal of physiology. Heart and circulatory physiology

    2024  Volume 326, Issue 4, Page(s) H877–H899

    Abstract: Cardiovascular aging is strongly associated with increased risk of cardiovascular disease and mortality. Moreover, health and lifestyle factors may accelerate age-induced alterations, such as increased arterial stiffness and wall dilation, beyond ... ...

    Abstract Cardiovascular aging is strongly associated with increased risk of cardiovascular disease and mortality. Moreover, health and lifestyle factors may accelerate age-induced alterations, such as increased arterial stiffness and wall dilation, beyond chronological age, making the clinical assessment of cardiovascular aging an important prompt for preventative action. Carotid flow waveforms contain information about age-dependent cardiovascular properties, and their ease of measurement via noninvasive Doppler ultrasound (US) makes their analysis a promising tool for the routine assessment of cardiovascular aging. In this work, the impact of different aging processes on carotid waveform morphology and derived indexes is studied in silico, with the aim of establishing the clinical potential of a carotid US-based assessment of cardiovascular aging. One-dimensional (1-D) hemodynamic modeling was employed to generate an age-specific virtual population (VP) of
    MeSH term(s) Humans ; Aged ; Aging ; Carotid Arteries/diagnostic imaging ; Hemodynamics ; Cardiovascular Diseases ; Ultrasonography
    Language English
    Publishing date 2024-01-12
    Publishing country United States
    Document type Journal Article
    ZDB-ID 603838-4
    ISSN 1522-1539 ; 0363-6135
    ISSN (online) 1522-1539
    ISSN 0363-6135
    DOI 10.1152/ajpheart.00304.2023
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Validation of an aging virtual population for the study of carotid hemodynamics.

    Suriani, Irene / Bouwman, R Arthur / Mischi, Massimo / Lau, Kevin D

    Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference

    2021  Volume 2021, Page(s) 4249–4252

    Abstract: The analysis of carotid ultrasound (US) flow, velocity, and diameter waveforms provides important information about cardiovascular and circulatory health. These can be used to derive clinical indices of atherosclerosis, vascular aging, and hemodynamic ... ...

    Abstract The analysis of carotid ultrasound (US) flow, velocity, and diameter waveforms provides important information about cardiovascular and circulatory health. These can be used to derive clinical indices of atherosclerosis, vascular aging, and hemodynamic status. To derive clinical insight from carotid waveforms, it is essential to understand the relationship of the observed variability in morphology with the underlying hemodynamic status and cardiovascular properties. For this purpose, using a one-dimensional modeling approach, we have developed and validated a virtual population that is able to realistically simulate carotid waveforms of healthy subjects aged between 10 and 80 years old.Clinical Relevance-Our virtual population of carotid waveforms can support the interpretation of US patient data. It can be used, e.g., to investigate how waveform morphology and derived indices relate to individual arterial and cardiac properties.
    MeSH term(s) Adolescent ; Adult ; Aged ; Aged, 80 and over ; Aging ; Carotid Arteries/diagnostic imaging ; Child ; Hemodynamics ; Humans ; Middle Aged ; Ultrasonography ; Young Adult
    Language English
    Publishing date 2021-12-05
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ISSN 2694-0604
    ISSN (online) 2694-0604
    DOI 10.1109/EMBC46164.2021.9630876
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Carotid Doppler ultrasound for non-invasive haemodynamic monitoring: a narrative review.

    Suriani, Irene / van Houte, Joris / de Boer, Esmée C / van Knippenberg, Luuk / Manzari, Sabina / Mischi, Massimo / Bouwman, R Arthur

    Physiological measurement

    2023  Volume 43, Issue 10

    Abstract: Objective. ...

    Abstract Objective.
    MeSH term(s) Humans ; Hemodynamic Monitoring ; Cardiac Output ; Monitoring, Physiologic ; Ultrasonography, Doppler
    Language English
    Publishing date 2023-03-01
    Publishing country England
    Document type Journal Article ; Review ; Research Support, Non-U.S. Gov't
    ZDB-ID 1149545-5
    ISSN 1361-6579 ; 0967-3334
    ISSN (online) 1361-6579
    ISSN 0967-3334
    DOI 10.1088/1361-6579/ac96cb
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Investigation of a Ballistocardiogram-Based Technique for Unobtrusive Monitoring of Fluid Accumulation in the Body

    Suriani, Irene / Bulut, Murtaza / van Lieshout, Ron / Bouma, Peter / Dellimore, Kiran

    Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference

    2020  Volume 2020, Page(s) 5146–5149

    Abstract: We introduce a novel monitoring solution for fluid accumulation in the human body (e.g. internal bleeding), based on observation of a selected energy-describing feature of the Ballistocardiogram (BCG) signal. It is hypothesized that, because of ... ...

    Abstract We introduce a novel monitoring solution for fluid accumulation in the human body (e.g. internal bleeding), based on observation of a selected energy-describing feature of the Ballistocardiogram (BCG) signal. It is hypothesized that, because of additional damping generated by the fluid, BCG signal energy decreases as compared to its baseline value. Data were collected from 15 human volunteers via accelerometers attached to the participants' body, and an electromechanical-film (EMFi) sensor-equipped bed. Fluid accumulation along the gastrointestinal (GI) tract was induced by means of water intake by the participants, and the BCG signal was recorded before and after intake. Based on performance evaluation, we selected a suitable energy feature and sensing channel amongst the ones investigated. The chosen feature showed a significant decrease in signal energy from baseline to after-intake condition (p-value<0.001), and identified the presence of fluid accumulation with high sensitivity (90% in bed-based, and 100% in standing-position monitoring).
    MeSH term(s) Ballistocardiography ; Drinking ; Humans
    Language English
    Publishing date 2020-10-05
    Publishing country United States
    Document type Journal Article
    ISSN 2694-0604
    ISSN (online) 2694-0604
    DOI 10.1109/EMBC44109.2020.9176094
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Evaluating corrected carotid flow time as a non-invasive parameter for trending cardiac output and stroke volume in cardiac surgery patients.

    van Houte, Joris / Raaijmaakers, Anniek E / Mooi, Frederik J / Meijs, Loek P B / de Boer, Esmée C / Suriani, Irene / Houterman, Saskia / Montenij, Leon J / Bouwman, Arthur R

    Journal of ultrasound

    2022  Volume 26, Issue 1, Page(s) 89–97

    Abstract: Purpose: The corrected carotid flow time (ccFT) is derived from a pulsed-wave Doppler signal at the common carotid artery. Several equations are currently used to calculate ccFT. Its ability to assess the intravascular volume status non-invasively has ... ...

    Abstract Purpose: The corrected carotid flow time (ccFT) is derived from a pulsed-wave Doppler signal at the common carotid artery. Several equations are currently used to calculate ccFT. Its ability to assess the intravascular volume status non-invasively has recently been investigated. The purpose of this study was to evaluate the correlation and trending ability of ccFT with invasive cardiac output (CO) and stroke volume (SV) measurements.
    Methods: Eighteen cardiac surgery patients were included in this prospective observational study. ccFT measurements were obtained at three time points: after induction of anesthesia (T1), after a passive leg raise (T2), and post-bypass (T3). Simultaneously, CO and SV were measured by calibrated pulse contour analysis. Three different equations (Bazett, Chambers, and Wodey) were used to calculate ccFT. The correlation and percentage change in time (concordance) between ccFT and CO and between ccFT and SV were evaluated.
    Results: Mean ccFT values differed significantly for the three equations (p < 0.001). The correlation between ccFT and CO and between ccFT and SV was highest for Bazett's (ρ = 0.43, p < 0.0001) and Wodey's (ρ = 0.33, p < 0.0001) equations, respectively. Concordance between ΔccFT and ΔCO and between ΔccFT and ΔSV was highest for Bazett's (100%) and Wodey's (82%) equations, respectively. Subgroup analysis demonstrated that correlation and concordance between SV and ccFT improved when assessed within limited heart rate (HR) ranges.
    Conclusion: The use of different ccFT equations leads to variable correlation and concordance rates between ccFT and CO/SV measurements. Bazett's equation acceptably tracked CO changes in time, while the trending capability of SV was poor.
    MeSH term(s) Humans ; Stroke Volume/physiology ; Cardiac Output/physiology ; Cardiac Surgical Procedures ; Carotid Arteries/diagnostic imaging ; Prospective Studies
    Language English
    Publishing date 2022-04-09
    Publishing country Italy
    Document type Observational Study ; Journal Article
    ZDB-ID 2365426-0
    ISSN 1876-7931 ; 1971-3495
    ISSN (online) 1876-7931
    ISSN 1971-3495
    DOI 10.1007/s40477-022-00678-z
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  6. Article ; Online: Correlation of Carotid Doppler Blood Flow With Invasive Cardiac Output Measurements in Cardiac Surgery Patients.

    van Houte, Joris / Mooi, Frederik J / Montenij, Leon J / Meijs, Loek P B / Suriani, Irene / Conjaerts, Bente C M / Houterman, Saskia / Bouwman, Arthur R

    Journal of cardiothoracic and vascular anesthesia

    2021  Volume 36, Issue 4, Page(s) 1081–1091

    Abstract: Objective: Carotid Doppler ultrasound has been a topic of recent interest, as it may be a promising noninvasive hemodynamic monitoring tool. In this study, the relation between carotid artery blood flow and invasive cardiac output (CO) was evaluated.: ...

    Abstract Objective: Carotid Doppler ultrasound has been a topic of recent interest, as it may be a promising noninvasive hemodynamic monitoring tool. In this study, the relation between carotid artery blood flow and invasive cardiac output (CO) was evaluated.
    Design: A prospective, observational study.
    Setting: A single-institution, tertiary referral hospital.
    Participants: Eighteen elective cardiac surgery patients.
    Interventions: CO was measured by calibrated pulse contour analysis. Simultaneously, carotid artery pulsed-wave Doppler measurements were obtained in the operating room in three clinical settings: after induction of anesthesia (T1), after a passive leg raise maneuverer (T2), and at the end of surgery (T3).
    Measurements and main results: Correlation and trending between carotid artery blood flow and invasive CO were evaluated. Furthermore, two Bland-Altman plots were constructed to evaluate the level of agreement between carotid artery-derived CO and invasive CO measurements. Carotid artery blood flow correlated moderately with invasive CO (ρ = 0.67, 95% confidence interval 0.56-0.76, p < 0.05). Concordance between the percentage change of carotid artery blood flow and invasive CO from T1 to T3 was 72%. The level of agreement between carotid artery-derived CO and invasive CO was ±2.29; ±2.57 L/min, with a bias of 0.1; -0.54 L/min, and mean error of 50% and 48%, for the two Bland-Altman analyses, respectively. Intraexamination precision was acceptable.
    Conclusions: In cardiac surgery patients, carotid artery blood flow correlated moderately with invasive CO measurements. However, the trending ability of carotid artery blood flow was poor, and carotid artery-derived CO tended not to be interchangeable with invasive CO.
    MeSH term(s) Cardiac Output/physiology ; Cardiac Surgical Procedures ; Humans ; Monitoring, Intraoperative ; Prospective Studies ; Reproducibility of Results ; Thermodilution
    Language English
    Publishing date 2021-10-05
    Publishing country United States
    Document type Journal Article ; Observational Study
    ZDB-ID 1067317-9
    ISSN 1532-8422 ; 1053-0770
    ISSN (online) 1532-8422
    ISSN 1053-0770
    DOI 10.1053/j.jvca.2021.09.043
    Database MEDical Literature Analysis and Retrieval System OnLINE

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