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  1. Article ; Online: Effects of gender and body weight on fibroblast growth factor 23 responsiveness to estimated dietary phosphorus.

    Ohta, Hiroyuki / Sakuma, Masae / Suzuki, Akitsu / Morimoto, Yuuka / Ishikawa, Makoto / Umeda, Minako / Arai, Hidekazu

    The journal of medical investigation : JMI

    2016  Volume 63, Issue 1-2, Page(s) 58–62

    Abstract: Fibroblast growth factor 23 (FGF23) is a molecule involved in regulating phosphorus homeostasis. Although some studies indicated an association between serum FGF23 levels and sex, the association has not been fully investigated. The purpose of this study ...

    Abstract Fibroblast growth factor 23 (FGF23) is a molecule involved in regulating phosphorus homeostasis. Although some studies indicated an association between serum FGF23 levels and sex, the association has not been fully investigated. The purpose of this study was to evaluate whether sex could influence FGF23 responsiveness to dietary phosphorus intake in healthy individuals. Thirty two healthy subjects between 21 and 28 years were recruited for this study. Subjects performed 24-hour urine collection and blood samples were collected. We estimated phosphorus intake (UC-P) from the urine collection (UC), and evaluated any association between UC-P and serum FGF23 levels. Subsequently, we compared serum FGF23 levels between males and females. Positive correlation was observed between UC-P and serum FGF23 levels. Serum FGF23 levels were significantly higher in males than in females. Serum FGF23 levels/UC-P was significantly higher in females than in males. There was no significant difference in serum FGF23 levels/UC-P/BW between the male and female groups. Our results indicate that there was no gender difference between FGF23 responsiveness to phosphorus intake per body weight.
    MeSH term(s) Adult ; Body Weight ; Female ; Fibroblast Growth Factors/blood ; Humans ; Male ; Phosphorus/urine ; Phosphorus, Dietary/administration & dosage ; Sex Characteristics ; Young Adult
    Chemical Substances Phosphorus, Dietary ; fibroblast growth factor 23 ; Phosphorus (27YLU75U4W) ; Fibroblast Growth Factors (62031-54-3)
    Language English
    Publishing date 2016
    Publishing country Japan
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1435233-3
    ISSN 1349-6867 ; 1343-1420
    ISSN (online) 1349-6867
    ISSN 1343-1420
    DOI 10.2152/jmi.63.58
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

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  2. Article ; Online: Effect of nutrient levels during the far-off period on postpartum productivity in dairy cows.

    Hirabayashi, Haruhi / Kawashima, Kenji / Okimura, Tomoko / Tateno, Ayane / Suzuki, Akitsu / Asakuma, Sadaki / Isobe, Naoki / Obitsu, Taketo / Kushibiki, Shiro / Sugino, Toshihisa

    Animal science journal = Nihon chikusan Gakkaiho

    2017  Volume 88, Issue 8, Page(s) 1162–1170

    Abstract: The present study aimed to determine the effects of differing nutrient levels during the far-off period on postpartum metabolism and milk production in lactating cows. Twenty-six multiparous cows were assigned to three dietary treatments in the far-off ... ...

    Abstract The present study aimed to determine the effects of differing nutrient levels during the far-off period on postpartum metabolism and milk production in lactating cows. Twenty-six multiparous cows were assigned to three dietary treatments in the far-off period: a low-energy diet (L, n = 9, 80% intake of the total digestible nutrients requirement), a moderate-energy diet (M, n = 8, 105%) and a high-energy diet (H, n = 9, 130%). During the close-up period, all cows were provided with 105% intake. After parturition, all cows were fed a lactation diet. The BCS recovery was slow, and low milk yield was found in the H group. In the L group, BCS recovery was favorable after parturition, and lactation persistence was increased. The L group had low rumen endotoxin activity and a high initial ovulation rate after parturition. These findings indicate that a high-energy diet during the far-off period has a deleterious effect on milk production. In contrast, the restricted diet in the far-off period increased adaptability with respect to peri-parturition metabolic changes, improved the post-parturition nutritional state, and increased milk production. Furthermore, it suggests that the nutrient levels in the far-off period affect rumen endotoxin activity and reproductive function after parturition.
    MeSH term(s) Animal Nutritional Physiological Phenomena/physiology ; Animals ; Cattle/physiology ; Diet/veterinary ; Endotoxins/metabolism ; Energy Intake/physiology ; Female ; Lactation ; Ovulation ; Parturition/physiology ; Postpartum Period/metabolism ; Postpartum Period/physiology ; Rumen/metabolism
    Chemical Substances Endotoxins
    Language English
    Publishing date 2017-08
    Publishing country Australia
    Document type Journal Article
    ZDB-ID 2095161-9
    ISSN 1740-0929 ; 1344-3941
    ISSN (online) 1740-0929
    ISSN 1344-3941
    DOI 10.1111/asj.12743
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Availability of 24-h urine collection method on dietary phosphorus intake estimation.

    Sakuma, Masae / Morimoto, Yuuka / Suzuki, Yukie / Suzuki, Akitsu / Noda, Saaya / Nishino, Kanaho / Ando, Sakiko / Ishikawa, Makoto / Arai, Hidekazu

    Journal of clinical biochemistry and nutrition

    2016  Volume 60, Issue 2, Page(s) 125–129

    Abstract: Accurate assessment of dietary phosphorus intake is necessary to prevent hyperphosphatemia. The aim of this study was to evaluate the 24-h urine collection method for estimation of phosphate intake in healthy males. Two experiments, a 1-day and a 5-day ... ...

    Abstract Accurate assessment of dietary phosphorus intake is necessary to prevent hyperphosphatemia. The aim of this study was to evaluate the 24-h urine collection method for estimation of phosphate intake in healthy males. Two experiments, a 1-day and a 5-day loading test, were performed. After an overnight fast, subjects consumed test meals, 24-h urine collection was performed, and blood samples were obtained. In the 5-day loading test, a phosphorus supplement was orally administered on day 3. The association between the phosphorus content of test meals and urinary excretion, anthropometric indices, and blood biomarkers was analyzed to develop a more precise formula for estimating phosphorus intake. In the 1-day loading test, the standard deviation of predictive phosphorus intake, based on multiple linear regression analysis, was less than that for the phosphorus absorption rate. In the 5-day loading test, urinary phosphorus excretion was similar on days 2, 4 and 5, but was significantly higher on day 3 after phosphorus supplementation. Our results indicate that estimation of dietary phosphorus intake with the 24-h urine collection method, using the amount of phosphorus and urea nitrogen excretion, may increase the precision of short-term monitoring.
    Language English
    Publishing date 2016-12-06
    Publishing country Japan
    Document type Journal Article
    ZDB-ID 632945-7
    ISSN 1880-5086 ; 0912-0009
    ISSN (online) 1880-5086
    ISSN 0912-0009
    DOI 10.3164/jcbn.16-50
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.B 2981: Show issues Location:
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  4. Article ; Online: Nocturnal eating disturbs phosphorus excretion in young subjects: a randomized crossover trial.

    Sakuma, Masae / Noda, Saaya / Morimoto, Yuuka / Suzuki, Akitsu / Nishino, Kanaho / Ando, Sakiko / Umeda, Minako / Ishikawa, Makoto / Arai, Hidekazu

    Nutrition journal

    2015  Volume 14, Page(s) 106

    Abstract: Background: Nocturnal eating have recently increased. Serum phosphorus levels and regulators of phosphorus have circadian variations, so it is suggested that the timing of eating may be important in controlling serum phosphorus levels. However, there ... ...

    Abstract Background: Nocturnal eating have recently increased. Serum phosphorus levels and regulators of phosphorus have circadian variations, so it is suggested that the timing of eating may be important in controlling serum phosphorus levels. However, there have been no reports on the effects of nocturnal eating on phosphorus metabolism. The objective was to evaluate the effects of nocturnal eating on phosphorus metabolism.
    Methods: Fourteen healthy men participated in two experimental protocols with differing dinner times. The design of this study was a crossover study. The subjects were served test meals three times (breakfast; 07:30 h, lunch; 12:30 h, dinner; 17:30 or 22:30 h) a day. Blood and urine samples were collected to assess diurnal variation until the following morning.
    Results: The following morning, fasting serum phosphorus levels in the late dinner group were markedly higher than those in the early dinner group (p < 0.001), although serum calcium levels were maintained at approximately constant levels throughout the day in both groups. Fluctuations in urinary calcium excretion were synchronized with the timing of dinner eating, however, fluctuations in urinary phosphorus excretion were not synchronized. Urinary phosphorus excretions at night were inhibited in the late dinner group. In the late dinner group, intact parathyroid hormone levels didn't decrease, and they were significantly higher in this group compared with the early dinner group at 20:00 h (p = 0.004). The following morning, fasting serum fibroblast growth factor 23 levels in the late dinner group had not changed, but those in the early dinner group were significantly increased (p = 0.003). Serum free fatty acid levels before dinner were significantly higher in the late dinner group compared with the early dinner group.
    Conclusions: Our results indicate that nocturnal eating inhibits phosphorus excretion. It is suggested that nocturnal eating should be abstained from to manage serum phosphorus levels to within an adequate range.
    MeSH term(s) Adult ; Circadian Rhythm ; Cross-Over Studies ; Feeding Behavior ; Humans ; Male ; Phosphorus/blood ; Phosphorus/urine ; Young Adult
    Chemical Substances Phosphorus (27YLU75U4W)
    Language English
    Publishing date 2015-10-08
    Publishing country England
    Document type Journal Article ; Randomized Controlled Trial ; Research Support, Non-U.S. Gov't
    ISSN 1475-2891
    ISSN (online) 1475-2891
    DOI 10.1186/s12937-015-0096-y
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Estimate of dietary phosphorus intake using 24-h urine collection.

    Morimoto, Yuuka / Sakuma, Masae / Ohta, Hiroyuki / Suzuki, Akitsu / Matsushita, Asami / Umeda, Minako / Ishikawa, Makoto / Taketani, Yutaka / Takeda, Eiji / Arai, Hidekazu

    Journal of clinical biochemistry and nutrition

    2014  Volume 55, Issue 1, Page(s) 62–66

    Abstract: Increases in serum phosphorus levels and dietary phosphorus intake induces vascular calcification, arterial sclerosis and cardiovascular diseases. Limiting phosphorus intake is advisable, however, no assessment methods are capable of estimating dietary ... ...

    Abstract Increases in serum phosphorus levels and dietary phosphorus intake induces vascular calcification, arterial sclerosis and cardiovascular diseases. Limiting phosphorus intake is advisable, however, no assessment methods are capable of estimating dietary phosphorus intake. We hypothesized that urinary phosphorus excretion can be translated into estimation of dietary phosphorus intake, and we evaluated whether a 24-h urine collection method could estimate dietary phosphorus intake. Thirty two healthy subjects were recruited for this study. Subjects collected urine samples over 24 h and weighed dietary records. We calculated dietary protein intake and phosphorus intake from dietary records and urine collection, and investigated associations between the two methods in estimating protein and phosphorus intake. Significant positive correlations were observed between dietary records and UC for protein and phosphorus intake. The average intakes determined from dietary records were significantly higher than from urine collection for both protein and phosphorus. There was a significant positive correlation between both the phosphorus and protein difference in dietary records and urine collection. The phosphorus-protein ratio in urine collection was significantly higher than in dietary records. Our data indicated that the 24-h urine collection method can estimate the amount of dietary phosphorus intake, and the results were superior to estimation by weighed dietary record.
    Language English
    Publishing date 2014-06-14
    Publishing country Japan
    Document type Journal Article
    ZDB-ID 632945-7
    ISSN 1880-5086 ; 0912-0009
    ISSN (online) 1880-5086
    ISSN 0912-0009
    DOI 10.3164/jcbn.14-15
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

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  6. Book: [Seishin'i ni kiku; seishinbyō to sono ryōyō no tebiki]

    Suzuki, Akitsu

    [Asking the psychiatrist; guide to mental illness and its treatment

    1962  

    MeSH term(s) Psychiatry
    Language Japanese
    Size 206 p.
    Publisher Toyokan Shuppansha
    Publishing place Tokyo
    Document type Book
    Database Catalogue of the US National Library of Medicine (NLM)

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