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  1. Book ; Online ; E-Book: Viral gastroenteritis

    Svensson, Lennart / Desselberger, Ulrich / Greenberg, Harry B. / Estes, Mary K.

    molecular epidemiology and pathogenesis

    2016  

    Author's details edited by Lennart Svensson, Ulrich Desselberger, Harry B. Greenberg, Mary K. Estes
    Keywords Gastroenteritis / virology ; Gastroenteritis / epidemiology ; RNA Virus Infections / virology ; Rotavirus / pathogenicity ; Norovirus / pathogenicity ; Avastrovirus / pathogenicity
    Subject code 616.3/3019
    Language English
    Size 1 Online-Ressource (xxvi, 563 Seiten), Illustrationen
    Publisher Elsevier AP
    Publishing place Amsterdam
    Publishing country Netherlands
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    HBZ-ID HT019448231
    ISBN 978-0-12-802659-5 ; 9780128022412 ; 0-12-802659-6 ; 0128022418
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Article ; Online: Viral Gastroenteritis: Sickness Symptoms and Behavioral Responses.

    Hellysaz, Arash / Neijd, Magdalena / Vesikari, Timo / Svensson, Lennart / Hagbom, Marie

    mBio

    2023  Volume 14, Issue 2, Page(s) e0356722

    Abstract: Viral infections have a major impact on physiology and behavior. The clinical symptoms of human rotavirus and norovirus infection are primarily diarrhea, fever, and vomiting, but several other sickness symptoms, such as nausea, loss of appetite, and ... ...

    Abstract Viral infections have a major impact on physiology and behavior. The clinical symptoms of human rotavirus and norovirus infection are primarily diarrhea, fever, and vomiting, but several other sickness symptoms, such as nausea, loss of appetite, and stress response are never or rarely discussed. These physiological and behavioral changes can be considered as having evolved to reduce the spread of the pathogen and increase the chances of survival of the individual as well as the collective. The mechanisms underlying several sickness symptoms have been shown to be orchestrated by the brain, specifically, the hypothalamus. In this perspective, we have described how the central nervous system contributes to the mechanisms underlying the sickness symptoms and behaviors of these infections. Based on published findings, we propose a mechanistic model depicting the role of the brain in fever, nausea, vomiting, cortisol-induced stress, and loss of appetite.
    MeSH term(s) Humans ; Infant ; Gastroenteritis ; Rotavirus Infections ; Norovirus ; Rotavirus ; Enteritis ; Vomiting/etiology ; Nausea/etiology ; Caliciviridae Infections ; Enterovirus Infections ; Feces
    Language English
    Publishing date 2023-03-28
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2557172-2
    ISSN 2150-7511 ; 2161-2129
    ISSN (online) 2150-7511
    ISSN 2161-2129
    DOI 10.1128/mbio.03567-22
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Rotavirus Downregulates Tyrosine Hydroxylase in the Noradrenergic Sympathetic Nervous System in Ileum, Early in Infection and Simultaneously with Increased Intestinal Transit and Altered Brain Activities.

    Hellysaz, Arash / Svensson, Lennart / Hagbom, Marie

    mBio

    2022  Volume 13, Issue 5, Page(s) e0138722

    Abstract: While rotavirus diarrhea has been considered to occur only due to intrinsic intestinal effects within the enteric nervous system, we provide evidence for central nervous system control underlying the clinical symptomology. Our data visualize infection by ...

    Abstract While rotavirus diarrhea has been considered to occur only due to intrinsic intestinal effects within the enteric nervous system, we provide evidence for central nervous system control underlying the clinical symptomology. Our data visualize infection by large-scale three-dimensional (3D) volumetric tissue imaging of a mouse model and demonstrate that rotavirus infection disrupts the homeostasis of the autonomous system by downregulating tyrosine hydroxylase in the noradrenergic sympathetic nervous system in ileum, concomitant with increased intestinal transit. Interestingly, the nervous response was found to occur before the onset of clinical symptoms. In adult infected animals, we found increased pS6 immunoreactivity in the area postrema of the brain stem and decreased phosphorylated STAT5-immunoreactive neurons in the bed nucleus of the stria terminalis, which has been associated with autonomic control, including stress response. Our observations contribute to knowledge of how rotavirus infection induces gut-nerve-brain interaction early in the disease.
    MeSH term(s) Mice ; Animals ; Rotavirus/metabolism ; Rotavirus Infections ; Tyrosine 3-Monooxygenase/metabolism ; STAT5 Transcription Factor ; Diarrhea ; Sympathetic Nervous System/metabolism ; Ileum ; Brain/metabolism
    Chemical Substances Tyrosine 3-Monooxygenase (EC 1.14.16.2) ; STAT5 Transcription Factor
    Language English
    Publishing date 2022-09-12
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2557172-2
    ISSN 2150-7511 ; 2161-2129
    ISSN (online) 2150-7511
    ISSN 2161-2129
    DOI 10.1128/mbio.01387-22
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Hur har omikron uppstått och varför sprider den sig så snabbt?

    Lennerstrand, Johan / Svensson, Lennart / Lundkvist, Åke

    Lakartidningen

    2022  Volume 119

    Abstract: Omicron has more than twenty new mutations in the S1 domain of the spike gene as compared to the other previously known variants of SARS-CoV-2. Many of these new mutations, especially those located in the receptor binding domain, are likely to improve ... ...

    Title translation How did Omicron evolve and why does this SARS-CoV-2 variant spread so fast?
    Abstract Omicron has more than twenty new mutations in the S1 domain of the spike gene as compared to the other previously known variants of SARS-CoV-2. Many of these new mutations, especially those located in the receptor binding domain, are likely to improve binding to the ACE2 receptor and to avoid binding to antibodies induced by a previous infection or by vaccination. Today there are several different hypotheses about the origin of Omicron, for example that it would have arisen in an immunosuppressed individual. Alternatively, a SARS-CoV-2 variant could have infected an unknown animal, and re-infection of humans would then have occurred. Furthermore, Omicron may have picked up a piece of a human common cold coronavirus.  The hitherto available data suggest that the rapid spread of Omicron is a combination of properties of the virus replication ability in addition to its ability to avoid pre-existing immune responses.
    MeSH term(s) Animals ; COVID-19 ; Humans ; SARS-CoV-2 ; Spike Glycoprotein, Coronavirus/genetics
    Chemical Substances Spike Glycoprotein, Coronavirus
    Language Swedish
    Publishing date 2022-01-18
    Publishing country Sweden
    Document type Journal Article
    ZDB-ID 391010-6
    ISSN 1652-7518 ; 0023-7205
    ISSN (online) 1652-7518
    ISSN 0023-7205
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Ua VI Zs.411: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  5. Book: Ammoniakavgång vid spridning av flytgödsel

    Svensson, Lennart

    grundläggande studier i klimatkammare och fält = Ammonia volatilization following application of livestock slurry to arable land

    (JTI-rapport ; 172)

    1994  

    Title variant Ammonia volatilization following application of livestock slurry to arable land
    Author's details Lennart Svensson
    Series title JTI-rapport ; 172
    Collection
    Keywords Gülledüngung ; Ammoniakemission ; Messung
    Subject Messen ; Messverfahren ; Messmethode ; Messkonzept ; Gülle
    Size 38 S. : graph. Darst.
    Publishing place Uppsala
    Publishing country Sweden
    Document type Book
    Note Zsfassung in engl. Sprache
    HBZ-ID HT006271444
    Database Catalogue ZB MED Nutrition, Environment, Agriculture

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    In stock of ZB MED Bonn / Germany

    Shelf markLoan statusLocation
    944/1174 available for loan (reading room) Freihandmagazin (U1)

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  6. Book ; Online: Markov Chain Monte Carlo Data Association for Sets of Trajectories

    Xia, Yuxuan / García-Fernández, Ángel F. / Svensson, Lennart

    2023  

    Abstract: This paper considers a batch solution to the multi-object tracking problem based on sets of trajectories. Specifically, we present two offline implementations of the trajectory Poisson multi-Bernoulli mixture (TPMBM) filter for batch data based on Markov ...

    Abstract This paper considers a batch solution to the multi-object tracking problem based on sets of trajectories. Specifically, we present two offline implementations of the trajectory Poisson multi-Bernoulli mixture (TPMBM) filter for batch data based on Markov chain Monte Carlo (MCMC) sampling of the data association hypotheses. In contrast to online TPMBM implementations, the proposed offline implementations solve a large-scale, multi-scan data association problem across the entire time interval of interest, and therefore they can fully exploit all the measurement information available. Furthermore, by leveraging the efficient hypothesis structure of TPMBM filters, the proposed implementations compare favorably with other MCMC-based multi-object tracking algorithms. Simulation results show that the TPMBM implementation using the Metropolis-Hastings algorithm presents state-of-the-art multiple trajectory estimation performance.

    Comment: Code will be released at https://github.com/yuhsuansia
    Keywords Electrical Engineering and Systems Science - Signal Processing
    Subject code 006
    Publishing date 2023-12-06
    Publishing country us
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

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  7. Book ; Online: Improving Open-Set Semi-Supervised Learning with Self-Supervision

    Wallin, Erik / Svensson, Lennart / Kahl, Fredrik / Hammarstrand, Lars

    2023  

    Abstract: Open-set semi-supervised learning (OSSL) embodies a practical scenario within semi-supervised learning, wherein the unlabeled training set encompasses classes absent from the labeled set. Many existing OSSL methods assume that these out-of-distribution ... ...

    Abstract Open-set semi-supervised learning (OSSL) embodies a practical scenario within semi-supervised learning, wherein the unlabeled training set encompasses classes absent from the labeled set. Many existing OSSL methods assume that these out-of-distribution data are harmful and put effort into excluding data belonging to unknown classes from the training objective. In contrast, we propose an OSSL framework that facilitates learning from all unlabeled data through self-supervision. Additionally, we utilize an energy-based score to accurately recognize data belonging to the known classes, making our method well-suited for handling uncurated data in deployment. We show through extensive experimental evaluations that our method yields state-of-the-art results on many of the evaluated benchmark problems in terms of closed-set accuracy and open-set recognition when compared with existing methods for OSSL. Our code is available at https://github.com/walline/ssl-tf2-sefoss.

    Comment: WACV2024
    Keywords Computer Science - Machine Learning ; Computer Science - Computer Vision and Pattern Recognition ; Statistics - Machine Learning
    Subject code 006
    Publishing date 2023-01-24
    Publishing country us
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Book ; Thesis: Ammonia volatilization from land spread livestock manure

    Svensson, Lennart

    effects of factors relating to meteorology, soil - manure and application technique

    1992  

    Author's details Lennart Svensson
    Keywords Boden ; Ammoniakemission ; Gülledüngung
    Subject Gülle ; Böden ; Erdboden ; Erde ; Erdreich
    Size Getr. Zählung : graph. Darst.
    Publisher Swedish Inst. of Agricultural Engineering
    Publishing place Uppsala
    Publishing country Sweden
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Uppsala, Swedish Univ. of Agricultural Sciences, Diss., 1993
    HBZ-ID HT004999235
    ISBN 91-576-4739-9 ; 978-91-576-4739-9
    Database Catalogue ZB MED Nutrition, Environment, Agriculture

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    In stock of ZB MED Bonn / Germany

    Shelf markLoan statusLocation
    AY 16365 order for loan Geschlossenes Magazin (U2)

    Order via subito

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  9. Book: Ammoniakavgång vid lagring av nöt- och svingödsel

    Svensson, Lennart

    = Emissions of ammonia during storage of cattle and pig manure

    (Meddelande / Jordbruktstekniska Institutet ; 433)

    1991  

    Title variant Emissions of ammonia during storage of cattle and pig manure
    Author's details [Lennart Svensson]
    Series title Meddelande / Jordbruktstekniska Institutet ; 433
    Meddelande / Jordbrukstekniska Institutet
    Collection Meddelande / Jordbrukstekniska Institutet
    Size 37 S. : graph. Darst.
    Publishing place Uppsala
    Publishing country Sweden
    Document type Book
    Note Zsfassung in engl. Sprache
    HBZ-ID HT006581719
    ISBN 91-7072-094-0 ; 978-91-7072-094-9
    Database Catalogue ZB MED Nutrition, Environment, Agriculture

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    In stock of ZB MED Bonn / Germany

    Shelf markLoan statusLocation
    958/869 available for loan (reading room) Freihandmagazin (U1)

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  10. Book: Begränsning av ammoniakavgång från flytgödselbehållare

    Svensson, Lennart

    en litteraturstudie = Ammonia losses from slurry storages

    (JTI-rapport ; 128)

    1991  

    Title variant Ammonia losses from slurry storages
    Author's details Lennart Svensson
    Series title JTI-rapport ; 128
    Collection
    Size 37, 3 Bl. : graph. Darst.
    Publishing place Uppsala
    Publishing country Sweden
    Document type Book
    Note Zsfassung in engl. Sprache
    HBZ-ID HT006844707
    Database Catalogue ZB MED Nutrition, Environment, Agriculture

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    In stock of ZB MED Bonn / Germany

    Shelf markLoan statusLocation
    964/39 available for loan (reading room) Freihandmagazin (U1)

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