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  1. Book ; Online ; E-Book: The Thorax

    Sverzellati, Nicola / Silva, Mario

    (Cancer Dissemination Pathways,)

    2020  

    Abstract: This book highlights the differences, in terms of neoplastic dissemination pathways, between various types of thoracic cancers. It presents and discusses a comprehensive schematic overview of tumors of the lung parenchyma, of the mediastinum, of the ... ...

    Author's details edited by Nicola Sverzellati, Mario Silva
    Series title Cancer Dissemination Pathways,
    Abstract This book highlights the differences, in terms of neoplastic dissemination pathways, between various types of thoracic cancers. It presents and discusses a comprehensive schematic overview of tumors of the lung parenchyma, of the mediastinum, of the pleura, and of the chest wall. For each tumor, it details the local spread and the lymphatic and vascular dissemination, and it describes the challenging staging of lung tumors with mutations. Illustrations and artwork enrich the content and help readers to understand and visualize tumor spread. The book is of great interest to professionals involved in the study, diagnosis and treatment of thoracic pathologies, as well as to residents in radiology, oncology and pulmonology.
    Keywords Radiology ; Oncology   ; Thoracic surgery ; Imaging / Radiology ; Oncology ; Thoracic Surgery
    Subject code 616.99494
    Language English
    Size 1 online resource (X, 199 p. 116 illus., 65 illus. in color.)
    Edition 1st ed. 2020.
    Publisher Springer International Publishing ; Imprint: Springer
    Publishing place Cham
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    ISBN 3-030-27233-8 ; 3-030-27232-X ; 978-3-030-27233-3 ; 978-3-030-27232-6
    DOI 10.1007/978-3-030-27233-3
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Book: Webb, Müller and Naidich's high-resolution CT of the lung

    Desai, Sujal / Devraj, Anand / Lynch, David A. / Sverzellati, Nicola / Elicker, Brett M.

    2021  

    Title translation High-resolution CT of the lung
    Title variant High-resolution CT of the lung
    Author's details Sujal R. Desai, Anand Devraj, David A. Lynch, Nicola Sverzellati, Brett M. Elicker
    Keywords Lungs/Tomography
    Subject code 616.24075722
    Language English
    Size xii, 715 Seiten, Illustrationen, Diagramme, 28 cm
    Edition Sixth edition
    Publisher Wolters Kluwer
    Publishing place Philadelphia
    Publishing country United States
    Document type Book
    Accompanying material Zugang zur Online-Ausgabe über Code
    HBZ-ID HT020876095
    ISBN 978-1-9751-4443-2 ; 1-9751-4443-0
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2021 A 478 available for loan (reading room) Lesesaal EG
    Zugang zur Online-Ausgabe über Code aus lizenzrechtlichen Gründen nicht verfügbar

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  3. Article ; Online: Deep learning-based radiomics: pacing immunotherapy in lung cancer.

    Sverzellati, Nicola / Marrocchio, Cristina

    The Lancet. Digital health

    2023  Volume 5, Issue 7, Page(s) e396–e397

    MeSH term(s) Humans ; Deep Learning ; Lung Neoplasms/diagnostic imaging ; Lung Neoplasms/therapy ; Immunotherapy
    Language English
    Publishing date 2023-05-31
    Publishing country England
    Document type Journal Article ; Comment
    ISSN 2589-7500
    ISSN (online) 2589-7500
    DOI 10.1016/S2589-7500(23)00086-9
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Giant Uterus and Vaginal Bleeding at 18 Weeks Gestation due to Complete Hydatiform Molar Pregnancy Co-Existing With a Healthy Fetus.

    Dall'Asta, Andrea / Berretta, Roberto / Sverzellati, Nicola / Ghi, Tullio

    Journal of obstetrics and gynaecology Canada : JOGC = Journal d'obstetrique et gynecologie du Canada : JOGC

    2024  , Page(s) 102344

    Language English
    Publishing date 2024-01-03
    Publishing country Netherlands
    Document type Editorial
    ZDB-ID 2171082-X
    ISSN 1701-2163
    ISSN 1701-2163
    DOI 10.1016/j.jogc.2023.102344
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 6445: Show issues Location:
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  5. Article ; Online: Body Composition at CT in Chronic Obstructive Pulmonary Disease: Regional Analysis Is Worthwhile.

    Sverzellati, Nicola / Cademartiri, Filippo

    Radiology

    2021  Volume 299, Issue 3, Page(s) 712–714

    MeSH term(s) Body Composition ; Humans ; Pulmonary Disease, Chronic Obstructive/diagnostic imaging ; Tomography, X-Ray Computed
    Language English
    Publishing date 2021-04-06
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 80324-8
    ISSN 1527-1315 ; 0033-8419
    ISSN (online) 1527-1315
    ISSN 0033-8419
    DOI 10.1148/radiol.2021204737
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Ue I Zs.106: Show issues Location:
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  6. Article ; Online: Is COVID Evolution Due to Occurrence of Pulmonary Vascular Thrombosis?

    Saba, Luca / Sverzellati, Nicola

    Journal of thoracic imaging

    2020  Volume 35, Issue 6, Page(s) 344–345

    Abstract: In this hypothesis paper, we suggest that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) may induce intravascular pulmonary thrombosis, which may result in the rapid worsening of clinical conditions and, eventually, exitus. Previously ... ...

    Abstract In this hypothesis paper, we suggest that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) may induce intravascular pulmonary thrombosis, which may result in the rapid worsening of clinical conditions and, eventually, exitus. Previously published papers have demonstrated that increased levels of D-dimer at hospital admission correlate with a more severe disease (0.5 mg/L) or occurrence of death (1 mg/L). The potential prothrombotic action of the SARS-CoV-2 is supported by the topographical involvement of the lung regions with a predilection for the lower lobe with peripheral involvement. If this hypothesis is demonstrated, this could suggest the benefit of using antithrombotic/coagulation regimens for SARS-CoV-2 and, at the same time, the urgency to identify drugs that could alter the inflammatory storm, thus protecting the vessel wall.
    MeSH term(s) COVID-19/blood ; COVID-19/complications ; COVID-19/physiopathology ; Fibrin Fibrinogen Degradation Products/metabolism ; Humans ; Lung/physiopathology ; Lung Diseases/blood ; Lung Diseases/etiology ; Lung Diseases/physiopathology ; SARS-CoV-2 ; Thrombosis/blood ; Thrombosis/etiology ; Thrombosis/physiopathology
    Chemical Substances Fibrin Fibrinogen Degradation Products ; fibrin fragment D
    Keywords covid19
    Language English
    Publishing date 2020-04-29
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 632900-7
    ISSN 1536-0237 ; 0883-5993
    ISSN (online) 1536-0237
    ISSN 0883-5993
    DOI 10.1097/RTI.0000000000000530
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2187: Show issues Location:
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    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  7. Article ; Online: Drug-induced interstitial lung disease.

    Spagnolo, Paolo / Bonniaud, Philippe / Rossi, Giulio / Sverzellati, Nicola / Cottin, Vincent

    The European respiratory journal

    2022  Volume 60, Issue 4

    Abstract: Interstitial lung disease (ILD) secondary to drug-induced lung injury is an increasingly common cause of morbidity and mortality. The number of drugs associated with the development of ILD continues to rise, mainly due to the use of novel monoclonal ... ...

    Abstract Interstitial lung disease (ILD) secondary to drug-induced lung injury is an increasingly common cause of morbidity and mortality. The number of drugs associated with the development of ILD continues to rise, mainly due to the use of novel monoclonal antibodies and biologicals for neoplastic and rheumatological diseases, and includes, among others, chemotherapeutics, molecular targeting agents, immune checkpoint inhibitors, antibiotics, antiarrhythmics and conventional or biological disease-modifying antirheumatic drugs. Drug-induced ILD (DI-ILD) manifests with a variety of clinical patterns, ranging from mild respiratory symptoms to rapidly progressive respiratory failure and death. In most cases, there are no pathognomonic clinical, laboratory, radiological or pathological features and the diagnosis of DI-ILD is suspected in the presence of exposure to a drug known to cause lung toxicity and after exclusion of alternative causes of ILD. Early identification and permanent discontinuation of the culprit drug are the cornerstones of treatment with systemic glucocorticoids being used in patients with disabling or progressive disease. However, for certain drugs, such as checkpoint inhibitors, the frequency of lung toxicity is such that mitigation strategies are put in place to prevent this complication, and occurrence of DI-ILD is not necessarily synonymous with permanent drug discontinuation, particularly in the absence of valid therapeutic alternatives.
    MeSH term(s) Humans ; Lung Diseases, Interstitial/diagnosis ; Antirheumatic Agents/therapeutic use ; Antibodies, Monoclonal ; Biological Factors
    Chemical Substances Antirheumatic Agents ; Antibodies, Monoclonal ; Biological Factors
    Language English
    Publishing date 2022-10-27
    Publishing country England
    Document type Journal Article ; Review ; Research Support, Non-U.S. Gov't
    ZDB-ID 639359-7
    ISSN 1399-3003 ; 0903-1936
    ISSN (online) 1399-3003
    ISSN 0903-1936
    DOI 10.1183/13993003.02776-2021
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 2322: Show issues Location:
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    Zs.MO 292: Show issues

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  8. Article ; Online: Thoracic computed tomography in the progressive fibrotic phenotype.

    Devaraj, Anand / Milanese, Gianluca / Sverzellati, Nicola

    Current opinion in pulmonary medicine

    2021  Volume 27, Issue 5, Page(s) 350–354

    Abstract: Purpose of review: To discuss rationale and methods for determining progressive lung fibrosis on thoracic computed tomography (CT) and describe limitations and challenges.: Recent findings: Identifying patients with progressive lung fibrosis is ... ...

    Abstract Purpose of review: To discuss rationale and methods for determining progressive lung fibrosis on thoracic computed tomography (CT) and describe limitations and challenges.
    Recent findings: Identifying patients with progressive lung fibrosis is important to determine optimal treatment. Serial high-resolution computed tomography is a method of determining disease progression. A number of studies are reviewed in this article, that have explored various parameters (both visual and automated) that signify progressive fibrosis on CT.
    Summary: To reliably use serial CT as a marker of disease progression in fibrotic lung disease, clinicians and radiologists need to be aware of the optimal methods for identifying changes in disease extent, and understand their limitations.
    MeSH term(s) Fibrosis ; Humans ; Lung/diagnostic imaging ; Phenotype ; Pulmonary Fibrosis/diagnostic imaging ; Retrospective Studies ; Tomography, X-Ray Computed
    Language English
    Publishing date 2021-07-17
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Review
    ZDB-ID 1285505-4
    ISSN 1531-6971 ; 1070-5287 ; 1078-1641
    ISSN (online) 1531-6971
    ISSN 1070-5287 ; 1078-1641
    DOI 10.1097/MCP.0000000000000804
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 4900: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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  9. Article ; Online: The Global Reading Room: Workup of Mediastinal Lymphadenopathy.

    Kim, Tae Jung / Little, Brent P / Manos, Daria / Sverzellati, Nicola

    AJR. American journal of roentgenology

    2022  Volume 220, Issue 2, Page(s) 301–302

    MeSH term(s) Humans ; Lymphadenopathy/diagnostic imaging ; Mediastinal Diseases/diagnostic imaging ; Mediastinum/diagnostic imaging ; Lymph Nodes ; Retrospective Studies
    Language English
    Publishing date 2022-05-18
    Publishing country United States
    Document type Journal Article
    ZDB-ID 82076-3
    ISSN 1546-3141 ; 0361-803X ; 0092-5381
    ISSN (online) 1546-3141
    ISSN 0361-803X ; 0092-5381
    DOI 10.2214/AJR.22.27984
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Ue I Zs.57: Show issues Location:
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  10. Article ; Online: Multiphase micro-computed tomography reconstructions provide dynamic respiratory function in a mouse lung fibrosis model.

    Pennati, Francesca / Belenkov, Sasha / Buccardi, Martina / Ferrini, Erica / Sverzellati, Nicola / Villetti, Gino / Aliverti, Andrea / Stellari, Franco Fabio

    iScience

    2024  Volume 27, Issue 3, Page(s) 109262

    Abstract: Micro-computed tomography derived functional biomarkers used in lung disease research can significantly complement end-stage histomorphometric measures while also allowing for longitudinal studies. However, no approach for visualizing lung dynamics ... ...

    Abstract Micro-computed tomography derived functional biomarkers used in lung disease research can significantly complement end-stage histomorphometric measures while also allowing for longitudinal studies. However, no approach for visualizing lung dynamics across a full respiratory cycle has yet been described. Using bleomycin-induced lung fibrosis and the antifibrotic drug nintedanib as a test model, we implemented a four-dimensional (4D) micro-CT imaging approach consisting of 30 reconstructed volumes per respiratory cycle, coupled with deep-learning-assisted segmentation of lung volumes. 4D micro-CT provided an accurate description of inhalatory and exhalatory lung dynamics under resting conditions and revealed an inflammation-related obstructive pattern at day 7, followed by a restrictive pattern associated with fibrosis development at day 21. A milder restriction and fibrotic pathology resulted from nintedanib treatment. The similarity of 4D micro-CT data with those produced by diagnostic measurements, also points to its great potential as an exploratory tool for the discovery of clinically relevant therapeutic compounds.
    Language English
    Publishing date 2024-02-16
    Publishing country United States
    Document type Journal Article
    ISSN 2589-0042
    ISSN (online) 2589-0042
    DOI 10.1016/j.isci.2024.109262
    Database MEDical Literature Analysis and Retrieval System OnLINE

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