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  1. Article: Haptics Vs Typodonts for Crown Preparation in Undergraduate Dental Student Education.

    Hadjichristou, C / Symeonidis, D / Dimitriadou, E

    The European journal of prosthodontics and restorative dentistry

    2024  

    Abstract: Objectives: This study aims to compare students' subjective perceptions and objective results by comparing two methods of crown preparation: typodonts and haptics.: Materials and methods: Fifty-four second-year students were given instructions on ... ...

    Abstract Objectives: This study aims to compare students' subjective perceptions and objective results by comparing two methods of crown preparation: typodonts and haptics.
    Materials and methods: Fifty-four second-year students were given instructions on crown preparation for the upper right second premolar. First on typodonts and then with haptics. They were given five minutes to familiarize with the artificial environment and then thirty minutes for the actual preparation. Finally, they completed a questionnaire about their experience. Their preparations were objectively compared by measuring the angle of total occlusal convergence-TOC on the typodonts and with haptics.
    Results: Students reported that haptics can enhance the learning process and that they would use them for skill training in the future. Overall, their experience was rated as positive. The TOC of teeth prepared with haptics was significantly higher than those prepared with typodonts, but all values were within the acceptable range.
    Conclusion: Although students did not prefer haptics to typodonts, haptics appear to be a powerful tool in the educational process because it can be a complementary option to traditional methods at the preclinical level.
    Language English
    Publishing date 2024-01-26
    Publishing country England
    Document type Journal Article
    ZDB-ID 1134782-x
    ISSN 0965-7452
    ISSN 0965-7452
    DOI 10.1922/EJPRD_2647Hadjichristou08
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Systemic immune response after open tension-free inguinal hernia repair under different anesthetic alternatives: a prospective comparative study.

    Symeonidis, D / Diamantis, A / Baloyiannis, I / Tzovaras, G / Tepetes, K

    Il Giornale di chirurgia

    2020  Volume 41, Issue 1, Page(s) 103–109

    Abstract: Purpose: The purpose of the present study was a comparison of the systemic inflammatory response intensity through the estimation of C- reactive protein and albumin levels before and after open tension free inguinal hernia repair performed under ... ...

    Abstract Purpose: The purpose of the present study was a comparison of the systemic inflammatory response intensity through the estimation of C- reactive protein and albumin levels before and after open tension free inguinal hernia repair performed under different anesthetic alternatives.
    Patients and methods: Totally, 125 inguinal hernia patients scheduled for unilateral primary open tension free inguinal repair unRomader local (50 patients), spinal (50 patients) and general anesthesia (25 patients) have been included in this prospective study.
    Results: The group of local anesthesia was associated with the higher postoperative serum levels of albumin compared to the group of general anesthesia (P 0.013). Local anesthesia was also associated with higher postoperative serum albumin levels compared to regional anesthesia but however the difference was not statistically significant (P 0.282). The group of local anesthesia was also associated with the lower postoperative levels of CRP compared to the regional (P 0.0094) and general anesthesia (P 0.0009) groups.
    Conclusion: Local anesthesia proved superior to regional or general anesthesia for open tension free inguinal hernia repair in the given patient sample from the standpoint of the inflammatory and acute phase response.
    MeSH term(s) Anesthesia/methods ; Anesthesia, General ; Anesthesia, Local ; Anesthesia, Spinal ; C-Reactive Protein/analysis ; Hernia, Inguinal/blood ; Hernia, Inguinal/immunology ; Hernia, Inguinal/surgery ; Herniorrhaphy/methods ; Herniorrhaphy/statistics & numerical data ; Humans ; Prospective Studies ; Serum Albumin/analysis ; Systemic Inflammatory Response Syndrome/immunology
    Chemical Substances Serum Albumin ; C-Reactive Protein (9007-41-4)
    Language English
    Publishing date 2020-02-10
    Publishing country Italy
    Document type Comparative Study ; Journal Article
    ZDB-ID 605974-0
    ISSN 1971-145X ; 0391-9005
    ISSN (online) 1971-145X
    ISSN 0391-9005
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  3. Article: BILE: A Literature Review Based Novel Clinical Classification and Treatment Algorithm of Iatrogenic Bile Duct Injuries.

    Symeonidis, Dimitrios / Tepetes, Konstantinos / Tzovaras, George / Samara, Athina A / Zacharoulis, Dimitrios

    Journal of clinical medicine

    2023  Volume 12, Issue 11

    Abstract: Purposes: The management of patients with iatrogenic bile duct injuries (IBDI) is a challenging field, often with dismal medico legal projections. Attempts to classify IBDI have been made repeatedly and the final results were either analytical and ... ...

    Abstract Purposes: The management of patients with iatrogenic bile duct injuries (IBDI) is a challenging field, often with dismal medico legal projections. Attempts to classify IBDI have been made repeatedly and the final results were either analytical and extensive but not useful in everyday clinical practice systems, or simple and user friendly but with limited clinical correspondence approaches. The purpose of the present review is to propose a novel, clinical classification system of IBDI by reviewing the relevant literature.
    Methods: A systematic literature review was conducted by performing bibliographic searches in the available electronic databases, including PubMed, Scopus, and the Cochrane Library.
    Results: Based on the literature results, we propose a five (5) stage (A, B, C, D and E) classification system for IBDI (BILE Classification). Each stage is correlated with the recommended and most appropriate treatment. Although the proposed classification scheme is clinically oriented, the anatomical correspondence of each IBDI stage has been incorporated as well, using the Strasberg classification.
    Conclusions: BILE classification represents a novel, simple, and dynamic in nature classification system of IBDI. The proposed classification focuses on the clinical consequences of IBDI and provides an action map that can appropriately guide the treatment plan.
    Language English
    Publishing date 2023-05-31
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2662592-1
    ISSN 2077-0383
    ISSN 2077-0383
    DOI 10.3390/jcm12113786
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  4. Article: Techniques and Current Role of Sentinel Lymph Node (SLN) Concept in Gastric Cancer Surgery.

    Symeonidis, Dimitrios / Tepetes, Konstantinos

    Frontiers in surgery

    2019  Volume 5, Page(s) 77

    Abstract: Gastric cancer patients represent a rather divergent patient group and in certain carefully selected cases of early forms of gastric cancer the D2 gastrectomy could be considered a more radical procedure than the biological and oncological ... ...

    Abstract Gastric cancer patients represent a rather divergent patient group and in certain carefully selected cases of early forms of gastric cancer the D2 gastrectomy could be considered a more radical procedure than the biological and oncological characteristics of the primary tumor on the gastric wall would require. As any unnecessary dissection increases morbidity without always respective survival benefits, an approach that could accurately predict and actually dictate the exact extent of lymph node dissection would be ideal. It is more than logical the assumption that the standard D2 lymphadenectomy could represent an overtreatment in distinct patients groups such as patients with early gastric cancer with favorable pathological characteristics and clinically negative nodes not suitable for endoscopic treatment because this early stage disease shows limited lymph node metastasis incidence and excellent overall survival. Considering that the D2 gastrectomy has a negative impact on the quality of life of gastric cancer patients due to the post-gastrectomy functional results, a concept of a more targeted lymph node dissection, when appropriate, is certainly appealing. It is yet to be proven whether sentinel lymph node navigation surgery can fulfill such expectations providing the appropriate balance between morbidity and oncological safety in selected gastric cancer patients.
    Language English
    Publishing date 2019-01-22
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2773823-1
    ISSN 2296-875X
    ISSN 2296-875X
    DOI 10.3389/fsurg.2018.00077
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  5. Article: From Classic Whipple to Pylorus Preserving Pancreaticoduodenectomy and Ultimately to Pylorus Resecting - Stomach Preserving Pancreaticoduodenectomy: A Review.

    Symeonidis, Dimitrios / Zacharoulis, Dimitrios / Kissa, Labrini / Samara, Athina A / Petsa, Eleana / Tepetes, Konstantinos

    Chirurgia (Bucharest, Romania : 1990)

    2023  Volume 118, Issue 4, Page(s) 335–347

    Abstract: Pancreaticoduodenectomy is the procedure of choice for benign or malignant tumors of the periampullary region. The preservation of the pylorus has been established as the mostly utilized approach during pancreaticoduodenectomy among the majority of ... ...

    Abstract Pancreaticoduodenectomy is the procedure of choice for benign or malignant tumors of the periampullary region. The preservation of the pylorus has been established as the mostly utilized approach during pancreaticoduodenectomy among the majority of specialized, in the surgical treatment of pancreatic cancer, centers worldwide. The factors that influenced this predilection are the shorter operation times, the less intraoperative blood loss, the decreased technical difficulty, and the quite similar short- and long-term outcomes compared to the classic Whipple. However, there is a notable trend in the literature highlighting the increased incidence of delayed gastric emptying following pylorus preserving pancreaticoduodenectomy. Among other factors, pylorus dysfunction attributable to the surgical maneuvers has been implemented in the etiology of this complication. In an attempt to overcome this limitation of the pylorus preserving pancreaticoduodenectomy, pylorus resecting pancreaticoduodenectomy with the preservation of the stomach was proposed. In theory, pylorus resecting pancreaticoduodenectomy could maintain the advantages of organ sparing surgery, but at the same time guarantee a more seamless gastric emptying. Only three RCTs, to date, aimed to evaluate the approach with only one reporting results in favor of the pylorus resecting pancreaticoduodenectomy in regard to the incidence of delayed gastric emptying. Further well-designed prospective randomized studies are needed for an accurate assessment of the true role of each of these surgical alternatives on the treatment of pancreatic cancer.
    MeSH term(s) Humans ; Pancreaticoduodenectomy ; Pylorus/surgery ; Gastroparesis/etiology ; Gastroparesis/prevention & control ; Prospective Studies ; Treatment Outcome ; Pancreatic Neoplasms/surgery ; Pancreatic Neoplasms
    Language English
    Publishing date 2023-09-12
    Publishing country Romania
    Document type Review ; Journal Article
    ZDB-ID 419244-8
    ISSN 1842-368X ; 1221-9118 ; 0009-4730 ; 0377-5003
    ISSN (online) 1842-368X
    ISSN 1221-9118 ; 0009-4730 ; 0377-5003
    DOI 10.21614/chirurgia.2023.v.118.i.4.p.335
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Central Pancreatectomy: Balancing between the Favorable Functional Results and the Increased Associated Morbidity.

    Symeonidis, Dimitrios / Paraskeva, Ismini / Samara, Athina A / Kissa, Labrini / Valaroutsos, Alexandros / Petsa, Eleana / Tepetes, Konstantinos

    Surgery journal (New York, N.Y.)

    2024  Volume 10, Issue 1, Page(s) e20–e24

    Abstract: ... ...

    Abstract Introduction
    Language English
    Publishing date 2024-03-14
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2864275-2
    ISSN 2378-5136 ; 2378-5128
    ISSN (online) 2378-5136
    ISSN 2378-5128
    DOI 10.1055/s-0044-1782655
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  7. Article ; Online: Comparison of ointment-based agents after excisional procedures for hemorrhoidal disease: a network meta-analysis of randomized controlled trials.

    Perivoliotis, Konstantinos / Chatzinikolaou, Charito / Symeonidis, Dimitrios / Tepetes, Konstantinos / Baloyiannis, Ioannis / Tzovaras, George

    Langenbeck's archives of surgery

    2023  Volume 408, Issue 1, Page(s) 401

    Abstract: Introduction: Efficient postoperative pain control is important after hemorrhoidal surgery. Although several locally applied medications have been used, current evidence regarding the optimal strategy is still conflicting. This network meta-analysis ... ...

    Abstract Introduction: Efficient postoperative pain control is important after hemorrhoidal surgery. Although several locally applied medications have been used, current evidence regarding the optimal strategy is still conflicting. This network meta-analysis assessed analgesic efficacy and safety of the various topical medications in patients submitted to excisional procedures for hemorrhoids.
    Methods: The present study followed the Cochrane Handbook for Systematic Reviews of Interventions and the PRISMA guidelines. The last systematic literature screening was performed at 15 June 2023. Comparisons were based on a random effects multivariate network meta-analysis under a Bayesian framework.
    Results: Overall, 26 RCTs and 2132 patients were included. Regarding postoperative pain, EMLA cream (surface under the cumulative ranking curve (SUCRA) 80.3%) had the highest ranking at 12-h endpoint, while aloe vera cream (SUCRA 82.36%) scored first at 24 h. Metronidazole ointments had the highest scores at 7 and 14 days postoperatively. Aloe vera had the best analgesic profile (24-h SUCRA 84.8% and 48-h SUCRA 80.6%) during defecation. Lidocaine (SUCRA 87.9%) displayed the best performance regarding overall morbidity rates.
    Conclusions: Due to the inconclusive results and several study limitations, further RCTs are required.
    MeSH term(s) Humans ; Hemorrhoids/surgery ; Ointments/therapeutic use ; Network Meta-Analysis ; Bayes Theorem ; Randomized Controlled Trials as Topic ; Pain, Postoperative ; Analgesics/therapeutic use
    Chemical Substances Ointments ; Analgesics
    Language English
    Publishing date 2023-10-14
    Publishing country Germany
    Document type Meta-Analysis ; Journal Article
    ZDB-ID 1423681-3
    ISSN 1435-2451 ; 1435-2443
    ISSN (online) 1435-2451
    ISSN 1435-2443
    DOI 10.1007/s00423-023-03128-4
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  8. Article ; Online: The role of the Rafaelo procedure in the management of hemorrhoidal disease: a systematic review and meta-analysis.

    Christodoulou, Prokopis / Baloyiannis, Ioannis / Perivoliotis, Konstantinos / Symeonidis, Dimitrios / Tzovaras, George

    Techniques in coloproctology

    2022  Volume 27, Issue 2, Page(s) 103–115

    Abstract: Background: The aim of this study was to summarize the current evidence regarding the role of the Rafaelo procedure in the management of hemorrhoidal disease (HD).: Methods: This study was based on the Cochrane Handbook for Systematic Reviews of ... ...

    Abstract Background: The aim of this study was to summarize the current evidence regarding the role of the Rafaelo procedure in the management of hemorrhoidal disease (HD).
    Methods: This study was based on the Cochrane Handbook for Systematic Reviews of Interventions and the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. A literature search was performed (Medline, Scopus, CENTRAL, and Web of Science) from inception to 25/09/2022. Grey literature databases were also reviewed. The primary endpoint was the pooled complications rate of the Rafaelo procedure in patients with HD. Secondary endpoints included short- (bleeding, pain, thrombosis, necrosis, urinary retention, fever, oedema, anal fissure, and readmission) and long-term (stenosis, meteorism, constipation, anal tags, anal hyposensibility, reoperation, and recurrence) postoperative complication rates. Both prospective and retrospective studies were considered. Quality evaluation was performed via the ROBINS-I tool. Certainty of Evidence was based on the Grading of Recommendations, Assessment, Development, and Evaluation (GRADE) methodology.
    Results: Overall, 6 non-randomized studies and 327 patients were included. The overall complication rate was 17.6% (95% CI 8.8-26.3%). Short-term complications were bleeding (7.5%, 95% CI 2.5-12.5%), thrombosis (2.2%, 95% CI 0.4-4.8%), and pain (1.6%, 95% CI 0.2-3.3%). Reoperation and recurrence rates were 1.8% (95% CI 0.3-3.4%) and 4.8% (95% CI 1.2-8.4%), respectively. A significant improvement in the presenting symptoms was noted. Method approval and patient satisfaction rates were 89.1% (95% CI 81.7-96.6%) and 95% (95% CI 89.8-100%), correspondingly. Overall CoE was "Very Low".
    Conclusions: Further randomized controlled trials are required to delineate the exact role of the Rafaelo procedure in HD.
    MeSH term(s) Humans ; Hemorrhoids/surgery ; Retrospective Studies ; Prospective Studies ; Neoplasm Recurrence, Local ; Pain
    Language English
    Publishing date 2022-11-13
    Publishing country Italy
    Document type Meta-Analysis ; Systematic Review ; Journal Article ; Review
    ZDB-ID 2083309-X
    ISSN 1128-045X ; 1123-6337
    ISSN (online) 1128-045X
    ISSN 1123-6337
    DOI 10.1007/s10151-022-02730-w
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  9. Article ; Online: The role of bursectomy in the surgical management of gastric cancer: a meta-analysis and systematic review.

    Perivoliotis, Konstantinos / Baloyiannis, Ioannis / Symeonidis, Dimitrios / Tepetes, Konstantinos

    Updates in surgery

    2020  Volume 72, Issue 4, Page(s) 939–950

    Abstract: In order to delineate the exact role of bursectomy (BS) in gastric cancer surgery, we designed and conducted the present meta-analysis. This meta-analysis adhered to the PRISMA guidelines and the Cochrane Handbook for Systematic Reviews of Interventions. ...

    Abstract In order to delineate the exact role of bursectomy (BS) in gastric cancer surgery, we designed and conducted the present meta-analysis. This meta-analysis adhered to the PRISMA guidelines and the Cochrane Handbook for Systematic Reviews of Interventions. A systematic literature review of the electronic databases (Medline, Scopus, Web of Science) was performed. Trial sequential analysis (TSA) was introduced for the validation of the pooled analyses. The level of evidence was attributed based on the GRADE approach. Overall, nine studies and 3599 patients were included in our meta-analysis. BS did not lead to an increase in the overall morbidity rate (OR 1.17, 95% CI 0.97-1.42, p = 0.09). Equivalence was, also, identified in all specific postoperative complications. Similarly, mortality rates were comparable (p = 0.69). Moreover, BS was related to a significantly higher operative time (p < 0.001) and perioperative blood loss (p = 0.002). Finally, resection of the omental bursa was not associated with improved R0 excision rates (p = 0.92), lymph node harvest (p = 0.1) or survival outcomes (OS p = 0.15 and DFS p = 0.97). BS displayed a suboptimal perioperative performance without any significant oncological efficacy. Due to certain limitations and the low level of evidence, further high-quality RCTs are required.
    MeSH term(s) Blood Loss, Surgical/statistics & numerical data ; Gastrectomy/methods ; Humans ; Operative Time ; Peritoneal Cavity/surgery ; Postoperative Complications/epidemiology ; Stomach Neoplasms/mortality ; Stomach Neoplasms/surgery ; Survival Rate ; Treatment Outcome
    Language English
    Publishing date 2020-06-03
    Publishing country Italy
    Document type Journal Article ; Meta-Analysis ; Systematic Review
    ZDB-ID 2572692-4
    ISSN 2038-3312 ; 2038-131X
    ISSN (online) 2038-3312
    ISSN 2038-131X
    DOI 10.1007/s13304-020-00801-x
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  10. Article: Surgical Repair of Iatrogenic Duodenal Injuries with a Roux-en-Y Duodenojejunostomy: A Physiology-oriented Approach.

    Symeonidis, Dimitrios / Samara, Athina A / Diamantis, Alexandros / Sgantzou, Ioanna-Konstantina / Floros, Theodoros / Zacharoulis, Dimitrios

    Chirurgia (Bucharest, Romania : 1990)

    2022  Volume 117, Issue 3, Page(s) 341–348

    Abstract: Introduction: ...

    Abstract Introduction:
    MeSH term(s) Aged, 80 and over ; Anastomosis, Roux-en-Y ; Duodenum/injuries ; Duodenum/surgery ; Female ; Humans ; Iatrogenic Disease ; Jejunum/surgery ; Male ; Treatment Outcome
    Language English
    Publishing date 2022-06-30
    Publishing country Romania
    Document type Journal Article
    ZDB-ID 419244-8
    ISSN 1842-368X ; 1221-9118 ; 0009-4730 ; 0377-5003
    ISSN (online) 1842-368X
    ISSN 1221-9118 ; 0009-4730 ; 0377-5003
    DOI 10.21614/chirurgia.2524
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