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  1. Book: Az agrárszakoktatás szerepe a mezögazdaság modernizációjában címü konferencia programmja

    Szabó, István

    1997. szeptember 23 - 25

    (Georgikon napok Keszthely ; 39)

    1999  

    Author's details [szerk.: Szabó István ...]
    Series title Georgikon napok Keszthely ; 39
    Collection
    Keywords Bulgarien ; Landwirtschaft ; Modernisierung ; Landwirt ; Ausbildung
    Subject Farmer ; Landwirte ; Agrarwirtschaft ; Agrarsektor ; Landwirtschaftlicher Sektor
    Language Hungarian
    Size 195 S. : graph. Darst., Kt.
    Publisher PATE, Georgikon Mezögazdaságtudományi Kar
    Publishing place Keszthely
    Publishing country Hungary
    Document type Book
    Note Zsfassung engl. und dt. Sprache
    HBZ-ID HT012792836
    ISBN 963-9096-67-9 ; 978-963-9096-67-7
    Database Catalogue ZB MED Nutrition, Environment, Agriculture

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  2. Article ; Online: Supporting grant reviewers through the scientometric ranking of applicants.

    Győrffy, Balázs / Weltz, Boglarka / Szabó, István

    PloS one

    2023  Volume 18, Issue 1, Page(s) e0280480

    Abstract: Introduction: Comparing the scientific output of different researchers applying for a grant is a tedious work. In Hungary, to help reviewers to rapidly rank the scientific productivity of a researcher, a grant decision support tool was established and ... ...

    Abstract Introduction: Comparing the scientific output of different researchers applying for a grant is a tedious work. In Hungary, to help reviewers to rapidly rank the scientific productivity of a researcher, a grant decision support tool was established and is available at www.scientometrics.org. In the present study, our goal was to assess the impact of this decision support tool on grant review procedures.
    Methods: The established, publicly available scientometric portal uses four metrics, including the H-index, the yearly citations without self-citations, the number of publications in the last five years, and the number of highly cited publications of a researcher within eleven independent scientific disciplines. Publication-age matched researchers are then ranked and the results are provided to grant reviewers. A questionnaire was completed by reviewers regarding utilization of the scientometric ranking system. The outcome of the grant selection was analyzed by comparing scientometric parameters of applying and funded applicants. We compared three grant allocation rounds before to two grant allocation rounds after the introduction of the portal.
    Results: The scientometric decision support tool was introduced in 2020 to assist grant selection in Hungary and all basic research grant applicants (n = 6,662) were screened. The average score of funded proposals compared to submitted proposals increased by 94% after the introduction of the ranking. Correlation between ranking scores and actual grant selection was strong in life and material sciences but some scientific panels had opposite correlation in social sciences and humanities. When comparing selection outcome to H-index across all applicants, both type I and type II errors decreased. All together 540 reviewers provided feedback representing all eleven scientific disciplines and 83.05% of the reviewers (especially younger reviewers) found the ranking useful.
    Conclusions: The scientometric decision support tool can save time and increase transparency of grant review processes. The majority of reviewers found the ranking-based scientometric analysis useful when assessing the publication performance of an applicant.
    MeSH term(s) Humans ; Financing, Organized ; Surveys and Questionnaires ; Efficiency ; Research Personnel ; Hungary
    Language English
    Publishing date 2023-01-20
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2267670-3
    ISSN 1932-6203 ; 1932-6203
    ISSN (online) 1932-6203
    ISSN 1932-6203
    DOI 10.1371/journal.pone.0280480
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Book: A növénytan és növényélettan története Keszthelyen

    Szabó, István / Almádi, László

    (Georgikon kiskönyvtár ; 6 : Tudománytörténeti füzet)

    1999  

    Author's details Szabó István ; Almádi László
    Series title Georgikon kiskönyvtár ; 6 : Tudománytörténeti füzet
    Collection
    Language Hungarian
    Size 145 S. : Ill.
    Publisher PATE, Georgikon Mezögazdaságtudományi Kar
    Publishing place Keszthely
    Publishing country Hungary
    Document type Book
    Note Zsfassung in engl. Sprache
    HBZ-ID HT012792898
    ISBN 963-9096-58-X ; 978-963-9096-58-5
    Database Catalogue ZB MED Nutrition, Environment, Agriculture

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  4. Article: Spatiotemporal Distribution of PRRSV-1 Clades in Hungary with a Focus on the Era of Disease Eradication.

    Bálint, Ádám / Jakab, Szilvia / Kaszab, Eszter / Marton, Szilvia / Bányai, Krisztián / Kecskeméti, Sándor / Szabó, István

    Animals : an open access journal from MDPI

    2024  Volume 14, Issue 1

    Abstract: Porcine reproductive and respiratory syndrome (PRRS) is the cause of the most severe economic losses in the pig industry worldwide. PRRSV is extremely diverse in Europe, which poses a significant challenge to disease control within a country or any ... ...

    Abstract Porcine reproductive and respiratory syndrome (PRRS) is the cause of the most severe economic losses in the pig industry worldwide. PRRSV is extremely diverse in Europe, which poses a significant challenge to disease control within a country or any region. With the combination of phylogenetic reconstruction and network analysis, we aimed to uncover the major routes of the dispersal of PRRSV clades within Hungary. In brief, by analyzing >2600 ORF5 sequences, we identified at least 12 clades (including 6 clades within lineage 1 and 3 clades within lineage 3) common in parts of Western Europe (including Denmark, Germany and the Netherlands) and identified 2 novel clades (designated X1 and X2). Of interest, some genetic clades unique to other central European countries, such as the Czech Republic and Poland, were not identified. The pattern of PRRSV clade distribution is consistent with the route of the pig trade among countries, showing that most of the identified clades were introduced from Western Europe when fatteners were transported to Hungary. As a result of rigorous implementation of the national eradication program, the swine population was declared officially free from PRRSV. This map of viral diversity and clade distribution will serve as valuable baseline information for the maintenance of PRRSV-free status in the post-eradication era.
    Language English
    Publishing date 2024-01-04
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2606558-7
    ISSN 2076-2615
    ISSN 2076-2615
    DOI 10.3390/ani14010175
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Development of a farm-specific real-time quantitative RT-PCR assay for the detection and discrimination of wild-type porcine reproductive respiratory syndrome virus and the vaccine strain in a farm under eradication.

    Fornyos, Kinga / Szabó, István / Lebhardt, Károly / Bálint, Ádám

    Acta veterinaria Hungarica

    2022  

    Abstract: Porcine reproductive and respiratory syndrome (PRRS) is one of the most important diseases of swine causing severe economic losses worldwide, therefore intensive efforts are taken to eliminate PRRS virus (PRRSV) from infected herds for complete ... ...

    Abstract Porcine reproductive and respiratory syndrome (PRRS) is one of the most important diseases of swine causing severe economic losses worldwide, therefore intensive efforts are taken to eliminate PRRS virus (PRRSV) from infected herds for complete eradication. The most efficient, fastest but at the same time the most expensive eradication method is depopulation-repopulation. In order to reduce costs, a number of farms prefer to perform their eradication process with continuous production using modified live vaccine (MLV) immunisation. However, the commercial PRRSV RT-PCR kits do not have the capacity to discriminate infected from vaccinated animals. In this paper, we describe a simple discriminatory duplex TaqMan RT-PCR assay based on common forward and reverse primers, as well as two differently labelled MLV- and wild-type PRRSV-specific probes. The discriminatory PCR test we designed is a fast and efficacious method for processing large quantities of samples. The assay is cheap, flexible, easy to apply in different herds using different MLVs, but should be checked, and can be modified based on the sequence data obtained during the permanent monitoring examinations. Owing to its simplicity the test can serve as a significant complementary assay for PRRS control and elimination/eradication.
    Language English
    Publishing date 2022-09-01
    Publishing country Hungary
    Document type Journal Article
    ZDB-ID 605742-1
    ISSN 1588-2705 ; 0236-6290 ; 0365-8198
    ISSN (online) 1588-2705
    ISSN 0236-6290 ; 0365-8198
    DOI 10.1556/004.2022.00020
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Development of a farm-specific real-time quantitative RT-PCR assay for the detection and discrimination of wild-type porcine reproductive respiratory syndrome virus and the vaccine strain in a farm under eradication

    Fornyos, Kinga / Szabó, István / Lebhardt, Károly / Bálint, Ádám

    Acta veterinaria Hungarica. 2022 Sept. 01,

    2022  

    Abstract: Porcine reproductive and respiratory syndrome (PRRS) is one of the most important diseases of swine causing severe economic losses worldwide, therefore intensive efforts are taken to eliminate PRRS virus (PRRSV) from infected herds for complete ... ...

    Abstract Porcine reproductive and respiratory syndrome (PRRS) is one of the most important diseases of swine causing severe economic losses worldwide, therefore intensive efforts are taken to eliminate PRRS virus (PRRSV) from infected herds for complete eradication. The most efficient, fastest but at the same time the most expensive eradication method is depopulation-repopulation. In order to reduce costs, a number of farms prefer to perform their eradication process with continuous production using modified live vaccine (MLV) immunisation. However, the commercial PRRSV RT-PCR kits do not have the capacity to discriminate infected from vaccinated animals. In this paper, we describe a simple discriminatory duplex TaqMan RT-PCR assay based on common forward and reverse primers, as well as two differently labelled MLV- and wild-type PRRSV-specific probes. The discriminatory PCR test we designed is a fast and efficacious method for processing large quantities of samples. The assay is cheap, flexible, easy to apply in different herds using different MLVs, but should be checked, and can be modified based on the sequence data obtained during the permanent monitoring examinations. Owing to its simplicity the test can serve as a significant complementary assay for PRRS control and elimination/eradication.
    Keywords Betaarterivirus suid 1 ; farms ; immunization ; live vaccines ; porcine reproductive and respiratory syndrome ; swine ; viruses
    Language English
    Dates of publication 2022-0901
    Publishing place Akadémiai Kiadó
    Document type Article
    ZDB-ID 605742-1
    ISSN 1588-2705 ; 0365-8198 ; 0236-6290
    ISSN (online) 1588-2705
    ISSN 0365-8198 ; 0236-6290
    DOI 10.1556/004.2022.00020
    Database NAL-Catalogue (AGRICOLA)

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  7. Article ; Online: MicroRNAs as Biomarkers and Therapeutic Targets in Heart Failure

    Szabó István Adorján / Frigy Atilla

    Acta Medica Marisiensis, Vol 65, Iss 3, Pp 77-

    2019  Volume 79

    Abstract: Heart failure still represents a real challenge both in everyday practice and research, due to the complex issues related to its pathogenesis and management. Humoral biomarkers have emerged in the last decades as useful tools in the diagnosis, risk ... ...

    Abstract Heart failure still represents a real challenge both in everyday practice and research, due to the complex issues related to its pathogenesis and management. Humoral biomarkers have emerged in the last decades as useful tools in the diagnosis, risk stratification and guiding the treatment of heart failure. These molecules are related to different pathological and adaptive processes, like myocardial injury, neurohormonal activation and cardiac remodeling, their most widespread representatives being the natriuretic peptides (e.g. NT-proBNP). The role of altered gene expression and transcription as the basis of myocardial structural and functional changes in heart failure is largely recognized. MicroRNAs (miRNAs) are non-coding RNAs which have a major role in post-transcriptional gene expression by interfering with messenger RNA molecules. Our short review summarizes the molecular biology of miRNAs and their possible role as biomarkers in the diagnosis and prognosis of heart failure. Furthermore, the therapeutical perspectives conferred by these molecules are also presented.
    Keywords mirna ; biomarkers ; heart failure ; Medicine ; R
    Subject code 610
    Language English
    Publishing date 2019-09-01T00:00:00Z
    Publisher Sciendo
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article ; Online: Slaughterhouse Visual and Palpation Method for Estimating the Economic Damage of Porcine Proliferative Enteropathy (PPE)

    Szabó, István / Makkai, István / Máté, Péter / Molnár, Tamás / Swam, Hanny / von Berg, Stephan / Holtkamp, Derald J. / Glávits, Róbert / Szabó, István / Ózsvári, László / Búza, László

    Animals. 2023 Feb. 03, v. 13, no. 3, p. 542

    2023  , Page(s) 542

    Abstract: Background: Ileitis is a wasting disease of pigs. Clinical symptoms are diarrhea in growing pigs, wasting and reduced performance. Ileitis is ubiquitous in pig producing countries all around the world. It is estimated that the economic losses caused by ... ...

    Abstract Background: Ileitis is a wasting disease of pigs. Clinical symptoms are diarrhea in growing pigs, wasting and reduced performance. Ileitis is ubiquitous in pig producing countries all around the world. It is estimated that the economic losses caused by the disease are USD 4.65 per fattening pig, and American pig farmers lose USD 56.1 million annually. It has become necessary to develop a slaughterhouse ileitis monitoring method that is simple, feasible to perform at modern slaughter lines, leads to immediate results and is cost effective. The practical experiences of applying the method are presented below. Methods: Our studies were performed on pig herds and slaughterhouses in Central European countries (Hungary, Romania, Poland, Croatia, and Slovakia). Experiences were evaluated based on visual and palpation. The results of our investigations were evaluated by a scoring method. Authors made histological and immunohistochemical examinations of investigated ileums. The hypothetic economic losses due to the disease in each farm were determined by estimating the loss of profit according to Holtkamp’s presentation in 2019. Results: The essentials of the method we have developed are: it can be performed during slaughterhouse processing, it does not interfere with or make it impossible to carry out normal technological processes, and the results of the procedure are correlated with the results of other laboratory diagnostic tests for ileitis (histology, immunohistochemistry, herd serology, fecal PCR). It is noteworthy that the results of the method can be used to immediately estimate the impact of Lawsonia intracellularis infection on the performance of the herd from which the slaughter animals come. Conclusion: Using the results of the slaughtered pigs’ visual and tactile examination at the slaughterhouse, the magnitude of the loss caused by Lawsonia intracellularis infection can be estimated quickly and accurately, and the return on investment of the strategy to be applied can be accurately planned.
    Keywords Lawsonia intracellularis ; cost effectiveness ; diarrhea ; farms ; herds ; immunohistochemistry ; porcine proliferative enteritis ; serology ; slaughter ; slaughterhouses ; swine ; Croatia ; Hungary ; Poland ; Romania ; Slovakia
    Language English
    Dates of publication 2023-0203
    Size p. 542
    Publishing place Multidisciplinary Digital Publishing Institute
    Document type Article ; Online
    ZDB-ID 2606558-7
    ISSN 2076-2615
    ISSN 2076-2615
    DOI 10.3390/ani13030542
    Database NAL-Catalogue (AGRICOLA)

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  9. Article ; Online: Overview of Registered Clinical Trials on Manual Therapy: Possible Implications of Genetic Testing for Personalized Treatment.

    Pozsgai, Miklos / Szabo, Istvan / Nusser, Nora / Varnai, Reka / Sipeky, Csilla

    In vivo (Athens, Greece)

    2022  Volume 36, Issue 1, Page(s) 294–305

    Abstract: Background/aim: Manual therapy (MT) is a frequently applied intervention offering individualized treatment in the clinic. In addition to the traditional approaches of MT, measuring molecular response to MT may offer better understanding of MT outcomes ... ...

    Abstract Background/aim: Manual therapy (MT) is a frequently applied intervention offering individualized treatment in the clinic. In addition to the traditional approaches of MT, measuring molecular response to MT may offer better understanding of MT outcomes in order to provide specific personalized treatment. The aim of this study was to summarize MT-related registered clinical trials, as well as to search for any evidence on MT and genetics.
    Patients and methods: A comprehensive search was conducted within the Clinical Trials database with predefined keywords mining for all types of MT-related clinical trials.
    Results: From the 47 trials, 20 had results and 27 had no results. MT alleviated pain and improved function almost in all trials. One registered clinical trial had investigated molecular outcomes of MT.
    Conclusion: MT is an effective and individualized treatment offering option in the management of several conditions. Interestingly, a clinical trial was found investigating molecular genetics and MT pinpointing an already existing link between genetics and MT. Therefore, further clinical trials may focus on genetics and MT for providing specific personalized treatment in future.
    MeSH term(s) Clinical Trials as Topic ; Exercise Therapy ; Genetic Testing ; Humans ; Musculoskeletal Manipulations ; Pain Management ; Precision Medicine
    Language English
    Publishing date 2022-01-01
    Publishing country Greece
    Document type Journal Article
    ZDB-ID 807031-3
    ISSN 1791-7549 ; 0258-851X
    ISSN (online) 1791-7549
    ISSN 0258-851X
    DOI 10.21873/invivo.12702
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Finding possible pharmacological effects of identified organic compounds in medicinal waters (BTEX and phenolic compounds).

    Szabó, István / Varga, Csaba

    International journal of biometeorology

    2019  Volume 64, Issue 6, Page(s) 989–995

    Abstract: Medicinal thermal waters consist of a mixture of different organic and inorganic compounds. Traditionally, these waters are only characterized and classified by their inorganic composition; however, the bioavailability of the majority of these inorganic ... ...

    Abstract Medicinal thermal waters consist of a mixture of different organic and inorganic compounds. Traditionally, these waters are only characterized and classified by their inorganic composition; however, the bioavailability of the majority of these inorganic compounds is limited. Many authors investigate the organic fractions of thermal waters. These authors propose that these compounds have a potential effect on health. To elucidate the underlying mechanisms, it is crucial to know the composition of the organic fractions. The absorption of these compounds on intact skin or mucosa is notable. Some of them have local anaesthetic effect or affect receptors in the central nervous system. In the knowledge of the chemical composition, we are able to estimate the possible pharmacological effect or might be able to assess possible toxicity risks. In the present article, we aim to review possible health effects of two of the identified organic fractions: benzene and alkylbenzenes and phenolic compounds that might correlate with the therapeutic effect on rheumatological or other diseases.
    MeSH term(s) Balneology ; Benzene ; Organic Chemicals ; Phenols ; Water
    Chemical Substances Organic Chemicals ; Phenols ; Water (059QF0KO0R) ; Benzene (J64922108F)
    Language English
    Publishing date 2019-10-31
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 280324-0
    ISSN 1432-1254 ; 0020-7128
    ISSN (online) 1432-1254
    ISSN 0020-7128
    DOI 10.1007/s00484-019-01808-9
    Database MEDical Literature Analysis and Retrieval System OnLINE

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