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  1. Article ; Online: Invasive Mechanical Ventilation.

    Szafran, Jennifer C / Patel, Bhakti K

    Critical care clinics

    2024  Volume 40, Issue 2, Page(s) 255–273

    Abstract: Invasive mechanical ventilation allows clinicians to support gas exchange and work of breathing in patients with respiratory failure. However, there is also potential for iatrogenesis. By understanding the benefits and limitations of different modes of ... ...

    Abstract Invasive mechanical ventilation allows clinicians to support gas exchange and work of breathing in patients with respiratory failure. However, there is also potential for iatrogenesis. By understanding the benefits and limitations of different modes of ventilation and goals for gas exchange, clinicians can choose a strategy that provides appropriate support while minimizing harm. The ventilator can also provide crucial diagnostic information in the form of respiratory mechanics. These, and the mechanical ventilation strategy, should be regularly reassessed.
    MeSH term(s) Humans ; Respiration, Artificial ; Respiratory Mechanics
    Language English
    Publishing date 2024-02-09
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 1006423-0
    ISSN 1557-8232 ; 0749-0704
    ISSN (online) 1557-8232
    ISSN 0749-0704
    DOI 10.1016/j.ccc.2024.01.003
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Interprofessional Education Without Limits: A Video-Based Workshop.

    Szafran, Jennifer C Houpy / Thompson, Katherine / Pincavage, Amber T / Saathoff, Mark / Kostas, Tia

    MedEdPORTAL : the journal of teaching and learning resources

    2021  Volume 17, Page(s) 11125

    Abstract: Introduction: Interprofessional collaboration improves patient outcomes. Many institutions lack access to learners from other health care professions, limiting the feasibility of many published interprofessional curricula. We created a video-based ... ...

    Abstract Introduction: Interprofessional collaboration improves patient outcomes. Many institutions lack access to learners from other health care professions, limiting the feasibility of many published interprofessional curricula. We created a video-based workshop to fill the need for an introductory interactive interprofessional activity for third-year medical students (MS 3) in their internal medicine clerkship, in which other health care students and standardized patients were not readily accessible.
    Methods: This session introduced medical students to the interprofessional model of care through a video workshop. Learners engaged in reflective observation as a video presented a physician interviewing a patient. The training and roles of interprofessional providers were discussed with the aid of video demonstrations. Learners completed postworkshop and postmedicine clerkship surveys with responses indicated using a Likert scale (1 =
    Results: Sixty-seven MS 3s participated in this workshop; postworkshop survey response rate was 82%. Of students who responded to the surveys, 87% agreed that the video increased their understanding of when it would be beneficial to consult interprofessional team members. Students' confidence in interacting with interprofessional team members improved from a mean of 3.0 before the workshop to 3.7 after the workshop. At the end of the medicine clerkship, 71% indicated that the video improved their ability to work with interprofessional team members at least moderately.
    Discussion: This video-based workshop improved students' self-rated understanding of interprofessional team members' roles and increased their confidence interacting with other members of the interprofessional health care team.
    MeSH term(s) Aged ; Curriculum ; Humans ; Interprofessional Education ; Interprofessional Relations ; Patient Care Team ; Students, Medical
    Language English
    Publishing date 2021-03-24
    Publishing country United States
    Document type Journal Article ; Research Support, U.S. Gov't, P.H.S.
    ISSN 2374-8265
    ISSN (online) 2374-8265
    DOI 10.15766/mep_2374-8265.11125
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Mitochondrial One-Carbon Metabolism is Required for TGF-β-Induced Glycine Synthesis and Collagen Protein Production.

    Meliton, Angelo Y / Cetin-Atalay, Rengül / Tian, Yufeng / Szafran, Jennifer C Houpy / Shin, Kun Woo D / Cho, Takugo / Sun, Kaitlyn A / Woods, Parker S / Shamaa, Obada R / Chen, Bohao / Muir, Alexander / Mutlu, Gökhan M / Hamanaka, Robert B

    bioRxiv : the preprint server for biology

    2023  

    Abstract: A hallmark of Idiopathic Pulmonary Fibrosis is the TGF-β-dependent activation of lung fibroblasts, leading to excessive deposition of collagen proteins and progressive scarring. We have previously shown that synthesis of collagen by lung fibroblasts ... ...

    Abstract A hallmark of Idiopathic Pulmonary Fibrosis is the TGF-β-dependent activation of lung fibroblasts, leading to excessive deposition of collagen proteins and progressive scarring. We have previously shown that synthesis of collagen by lung fibroblasts requires
    Language English
    Publishing date 2023-11-07
    Publishing country United States
    Document type Preprint
    DOI 10.1101/2023.11.07.566074
    Database MEDical Literature Analysis and Retrieval System OnLINE

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