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  1. Article ; Online: When More Could Mean Less Intervention: The Tale Of Tracheostomy Timing in Critical Illness.

    Szakmany, Tamas

    Critical care medicine

    2023  Volume 51, Issue 2, Page(s) 333–335

    MeSH term(s) Humans ; Tracheostomy ; Critical Illness/therapy ; Respiration, Artificial ; Time Factors ; Critical Care
    Language English
    Publishing date 2023-01-20
    Publishing country United States
    Document type Journal Article
    ZDB-ID 197890-1
    ISSN 1530-0293 ; 0090-3493
    ISSN (online) 1530-0293
    ISSN 0090-3493
    DOI 10.1097/CCM.0000000000005753
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1261: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  2. Article ; Online: Anesthesia and immunomodulation: from basic science to clinical trials.

    Szakmany, Tamas

    Minerva anestesiologica

    2020  Volume 86, Issue 2, Page(s) 126–128

    MeSH term(s) Anesthesia ; Anesthesiology ; Anesthetics ; Immunomodulation ; Perioperative Medicine
    Chemical Substances Anesthetics
    Language English
    Publishing date 2020-03-02
    Publishing country Italy
    Document type Editorial ; Comment
    ZDB-ID 123584-9
    ISSN 1827-1596 ; 0026-4717 ; 0375-9393
    ISSN (online) 1827-1596
    ISSN 0026-4717 ; 0375-9393
    DOI 10.23736/S0375-9393.19.14327-1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 516: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 192: Show issues

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  3. Article ; Online: Noninvasive ventilatory support in COVID-19: operating in the evidence free zone.

    Szakmany, Tamas

    Minerva anestesiologica

    2020  Volume 86, Issue 11, Page(s) 1126–1128

    MeSH term(s) COVID-19/therapy ; Humans ; Noninvasive Ventilation
    Keywords covid19
    Language English
    Publishing date 2020-10-15
    Publishing country Italy
    Document type Editorial
    ZDB-ID 123584-9
    ISSN 1827-1596 ; 0026-4717 ; 0375-9393
    ISSN (online) 1827-1596
    ISSN 0026-4717 ; 0375-9393
    DOI 10.23736/S0375-9393.20.15158-7
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 516: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
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    Zs.MO 192: Show issues

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  4. Article ; Online: The authors reply.

    Villar, Jesús / González-Martin, Jesús M / Szakmany, Tamas

    Critical care medicine

    2024  Volume 52, Issue 2, Page(s) e106–e107

    Language English
    Publishing date 2024-01-19
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 197890-1
    ISSN 1530-0293 ; 0090-3493
    ISSN (online) 1530-0293
    ISSN 0090-3493
    DOI 10.1097/CCM.0000000000006115
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1261: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  5. Article ; Online: Intravenous immunoglobulin in sepsis: can we find the right dose?

    Szakmany, Tamas

    Minerva anestesiologica

    2018  Volume 85, Issue 2, Page(s) 115–117

    MeSH term(s) Historically Controlled Study ; Humans ; Immunoglobulins, Intravenous ; Retrospective Studies ; Sepsis ; Shock, Septic
    Chemical Substances Immunoglobulins, Intravenous
    Language English
    Publishing date 2018-10-30
    Publishing country Italy
    Document type Editorial ; Comment
    ZDB-ID 123584-9
    ISSN 1827-1596 ; 0026-4717 ; 0375-9393
    ISSN (online) 1827-1596
    ISSN 0026-4717 ; 0375-9393
    DOI 10.23736/S0375-9393.18.13349-9
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 516: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 192: Show issues

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  6. Article ; Online: The role of rotational thromboelastometry in understanding the coagulation problems in COVID-19 associated critical illness.

    Duric, Natalie / Szakmany, Tamas

    Anaesthesiology intensive therapy

    2022  Volume 53, Issue 4, Page(s) 336–342

    Abstract: In critically ill patients with COVID-19, concomitant abnormalities of coagulation have been seen with an unusually high incidence, often despite seemingly appropriate prophylactic anti-coagulation. It appears that standard coagulation tests are limited ... ...

    Abstract In critically ill patients with COVID-19, concomitant abnormalities of coagulation have been seen with an unusually high incidence, often despite seemingly appropriate prophylactic anti-coagulation. It appears that standard coagulation tests are limited in their ability to accurately reflect the severity of the prothrombotic phenotype observed in severe COVID-19 infections. In this narrative review we consider the role of a global haemostatic assay, rotational thromboelastometry (ROTEM), as a near bedside test allowing a more comprehensive assessment of haemostatic function in the context of COVID-19 infection. A comprehensive literature search was conducted on PubMed using the keywords "COVID-19" OR "SARS-CoV-2" AND "Rotational thromboelastometry". Sixteen original articles were included for analysis and two existing literature reviews were considered. Whilst not the perfect substitute for in vivo coagulation, studies utilising rotational thromboelastometry assays in COVID-19 patients have demonstrated increased maximum clot firmness (consistent with hypercoagulability) and reduced maximum lysis (consistent with "fibrinolytic shutdown"). There is a possible association with disease severity and degree of hypercoagulability and hypofibrinolysis as a possible tool for risk stratification and the potential modulation of fibrinogen-dependent maximum clot firmness with enhanced anticoagulation strategies. Precisely how these coagulation abnormalities can be modified by optimum, individualised medical interventions to improve clinical outcomes, however, remains unclear.
    MeSH term(s) Blood Coagulation ; COVID-19/complications ; Critical Illness ; Humans ; SARS-CoV-2 ; Thrombelastography
    Language English
    Publishing date 2022-03-08
    Publishing country Poland
    Document type Journal Article ; Review
    ISSN 1731-2531
    ISSN (online) 1731-2531
    DOI 10.5114/ait.2021.109401
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Redefining ARDS: a paradigm shift.

    Villar, Jesús / Szakmany, Tamas / Grasselli, Giacomo / Camporota, Luigi

    Critical care (London, England)

    2023  Volume 27, Issue 1, Page(s) 416

    Abstract: Although the defining elements of "acute respiratory distress syndrome" (ARDS) have been known for over a century, the syndrome was first described in 1967. Since then, despite several revisions of its conceptual definition, it remains a matter of debate ...

    Abstract Although the defining elements of "acute respiratory distress syndrome" (ARDS) have been known for over a century, the syndrome was first described in 1967. Since then, despite several revisions of its conceptual definition, it remains a matter of debate whether ARDS is a discrete nosological entity. After almost 60 years, it is appropriate to examine how critical care has modeled this fascinating syndrome and affected patient's outcome. Given that the diagnostic criteria of ARDS (e.g., increased pulmonary vascular permeability and diffuse alveolar damage) are difficult to ascertain in clinical practice, we believe that a step forward would be to standardize the assessment of pulmonary and extrapulmonary involvement in ARDS to ensure that each patient can receive the most appropriate and effective treatment. The selection of treatments based on arbitrary ranges of PaO
    MeSH term(s) Humans ; Respiratory Distress Syndrome/therapy ; Respiratory Distress Syndrome/drug therapy ; Lung ; Treatment Outcome ; Critical Care
    Language English
    Publishing date 2023-10-31
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2041406-7
    ISSN 1466-609X ; 1364-8535
    ISSN (online) 1466-609X
    ISSN 1364-8535
    DOI 10.1186/s13054-023-04699-w
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5517: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  9. Article: Sepsis outcomes in patients with pre-existing liver disease.

    Kopczynska, Maja / Szakmany, Tamas

    Clinical and experimental hepatology

    2021  Volume 7, Issue 4, Page(s) 358–363

    Abstract: Aim of the study: To determine the characteristics, including the use of various diagnostic criteria, outcomes and treatment strategies in septic patients treated outside of the critical care area with pre-existing liver disease (LD).: Material and ... ...

    Abstract Aim of the study: To determine the characteristics, including the use of various diagnostic criteria, outcomes and treatment strategies in septic patients treated outside of the critical care area with pre-existing liver disease (LD).
    Material and methods: The study population included patients recruited into two annual 24-hour prospective point-prevalence studies on the general wards and emergency departments across all Welsh acute hospitals in 2016 and 2017. Data were collected on patient demographics, observations and SIRS, SOFA and qSOFA scores.
    Results: Out of 839 recruited patients, 24 (2.9%) had a past medical history of LD. 12/24 (50%) had a SIRS score ≥ 2, 21/24 (87.5%) a SOFA score ≥ 2 and 3/24 (12.5%) a qSOFA score ≥ 2. Patients with LD had 2.4 times higher odds (95% CI = 1.07-5.53,
    Conclusions: The 90-day mortality was greater in patients with LD than the rest of the population. Management of sepsis in LD patients poses a challenge with current therapeutic bundles being underused and of unclear significance in improving patient outcome.
    Language English
    Publishing date 2021-12-10
    Publishing country Poland
    Document type Journal Article
    ZDB-ID 2937940-4
    ISSN 2449-8238 ; 2392-1099
    ISSN (online) 2449-8238
    ISSN 2392-1099
    DOI 10.5114/ceh.2021.111421
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Cytokine inhibitors in COVID-19: looking back to move forward.

    Szakmany, Tamas / Duric, Natalie

    Minerva anestesiologica

    2021  Volume 87, Issue 8, Page(s) 848–850

    MeSH term(s) COVID-19 ; Cytokines ; Humans ; SARS-CoV-2
    Chemical Substances Cytokines
    Language English
    Publishing date 2021-09-12
    Publishing country Italy
    Document type Journal Article ; Comment
    ZDB-ID 123584-9
    ISSN 1827-1596 ; 0026-4717 ; 0375-9393
    ISSN (online) 1827-1596
    ISSN 0026-4717 ; 0375-9393
    DOI 10.23736/S0375-9393.21.15837-7
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 516: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 192: Show issues

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