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Article ; Online: In memoriam prof. dr. Entz László (1951-2023).

Sótonyi, Péter / Szeberin, Zoltán

2023 Volume 76, Issue 2, Page(s) 83–84

Language	English
Publishing date	2023-06-02
Publishing country	Hungary
Document type	Journal Article
ZDB-ID	414068-0
ISSN	1789-4301 ; 0025-0295
ISSN (online)	1789-4301
ISSN	0025-0295
DOI	10.1556/1046.2023.20005
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Article ; Online: Homograftok használata érsebészeti fertőzésekben.

Garbaisz, Dávid / Szeberin, Zoltán / Hidi, László / Sótonyi, Péter

Orvosi hetilap

2023 Volume 164, Issue 32, Page(s) 1256–1262

Abstract: With the growing number of patients with vascular endografts, the number of patients with graft infections has also increased. Septic conditions and the choice of grafts are an important challenge in vascular surgery. The aim of this study was to review ... ...

Title translation	Use of allografts in vascular surgery infections.
Abstract	With the growing number of patients with vascular endografts, the number of patients with graft infections has also increased. Septic conditions and the choice of grafts are an important challenge in vascular surgery. The aim of this study was to review the literature of the last 7 years showing allograft use in septic conditions in vascular surgery which helps provide insight into the current results of vascular allografts. Data were collected between 1st January 2016 and 31st December 2022. A systematic search was conducted for publications of cryopreserved allograft usage for vascular infection in PubMed and Medline databases. The results of the publications were reviewed based on the following key endpoints: study design, patient's characteristics, mortality rate, graft related complication and reintervention rate, graft patency, limb salvage, graft reinfection rate and survival rate. After a systematic search, 16 publications were included. The articles were divided into two groups: aortic and peripheral. The aortic group included 12 studies covering the data of 542 patients. Early mortality rate (<30 days) was between 2.8% and 42.8%. Allograft-related reintervention rates ranged between 5.9% and 29% (early and late). The rate of graft reinfection was below 10%. 4 studies were included in the peripheral group covering the data of 252 patients. Early mortality rate (<30 days) was between 2.0% and 38%. Allograft-related reintervention rates ranged between 4.0% and 55% (early and late). Reinfection rate was around 4%, but only poor quality data were available. Infections in vascular surgery remain a challenging problem, however, cryopreserved allografts show low reinfection rate and reasonable durability, thus, allografts may be an acceptable option for reconstruction. Orv Hetil. 2023; 164(32): 1256-1262.
MeSH term(s)	Humans ; Blood Vessel Prosthesis/adverse effects ; Blood Vessel Prosthesis Implantation/adverse effects ; Reinfection/complications ; Prosthesis-Related Infections/surgery ; Prosthesis-Related Infections/etiology ; Treatment Outcome ; Allografts/surgery ; Retrospective Studies ; Cryopreservation
Language	Hungarian
Publishing date	2023-08-13
Publishing country	Hungary
Document type	Review ; English Abstract ; Journal Article
ZDB-ID	123879-6
ISSN	1788-6120 ; 0030-6002
ISSN (online)	1788-6120
ISSN	0030-6002
DOI	10.1556/650.2023.32830
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Article ; Online: Aortoiliacalis stenoocclusiv betegség fedett sztentekkel végzett endovascularis ellátásával szerzett kezdeti tapasztalataink.

Hidi, László / Lengyel, Balázs / Legeza, Péter / Szeberin, Zoltán

Orvosi hetilap

2022 Volume 163, Issue 39, Page(s) 1553–1558

Abstract: Introduction: Treatment for complex aortoiliac stenoocclusive disease traditionally is open surgical repair. Endovascular approach is associated with less perioperative stress for the patient, and is a reasonable solution. Covered stent implantation is ... ...

Abstract	Introduction: Treatment for complex aortoiliac stenoocclusive disease traditionally is open surgical repair. Endovascular approach is associated with less perioperative stress for the patient, and is a reasonable solution. Covered stent implantation is an alternative treatment option in this patient population even in the case of aortobiiliac or aortobifemoral bypasses. Objective: Assessing outcomes of aortoiliac covered stent implantation at our vascular center. Method: We retrospectively analysed the data of 36 prospectively registered, consecutive patients who underwent aortoiliac covered stent implantations at our department between the 1th November 2019 and 30th September 2021. Medical records, perioperative complications, preoperative and postoperative Rutherford stages and ankle-brachial index were recorded. One-year survival and primary patency as primary endpoints were presented on Kaplan-Meier curve. Our secondary endpoints were change of the ankle-brachial index and Rutherford stage, and the incidence of the major amputation. Results: 36 patients were included in the study. Mean follow-up time was 12 ± 6.9 months. TASC C-D aortoiliac lesions were the indication of the procedures in 72.2% (n = 26). Patients had critical limb ischaemia in 44% (n = 16). In 64% (n = 23), interventions were performed via percutaneous puncture. In-hospital stay was 5 ± 7 days. Perioperative bleeding and reoperation occured in 4 (11.1%) and 6 (16.6%) cases, respectively. Perioperative mortality was zero. The one-year survival and primary patency were 94.3% and 91.4%, respectively. The postoperative Rutherford stage (3 [2] vs. 1 [1]; p<0.001) and ankle-brachial index (0.4 [0.55] vs. 1 [0.4]; p<0.001) improved significantly compared to the preoperative ones. Unplanned major amputation was not performed. Conclusion: Significant clinical improvement with low perioperative mortality, acceptable morbidity and high one-year primary patency and survival can be obtained by the use of covered stents in the treatment of aortoiliac stenoocclusive disease. This procedure can be an alternative to open surgical repair. Orv Hetil. 2022; 163(39): 1553-1558.
MeSH term(s)	Arterial Occlusive Diseases/surgery ; Endovascular Procedures ; Humans ; Iliac Artery/surgery ; Prosthesis Design ; Retrospective Studies ; Risk Factors ; Stents ; Treatment Outcome ; Vascular Patency
Language	English
Publishing date	2022-09-25
Publishing country	Hungary
Document type	Journal Article
ZDB-ID	123879-6
ISSN	1788-6120 ; 0030-6002
ISSN (online)	1788-6120
ISSN	0030-6002
DOI	10.1556/650.2022.32591
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Article ; Online: Percutan endovascularis aortarekonstrukcióval szerzett kezdeti tapasztalataink.

Berczeli, Márton / Osztrogonácz, Péter / Hidi, László / Szeberin, Zoltán

Orvosi hetilap

2022 Volume 163, Issue 33, Page(s) 1318–1323

Abstract: Introduction: Percutaneous aortic reconstruction is another milestone in aortic surgery. The evolution of vascular closure devices played a key role by enabling arterial closure after large-bore endovascular devices without the need of arterial cut-down. ...

Abstract	Introduction: Percutaneous aortic reconstruction is another milestone in aortic surgery. The evolution of vascular closure devices played a key role by enabling arterial closure after large-bore endovascular devices without the need of arterial cut-down. Objective: Our objective was to determine technical success of percutaneous endovascular aortic repair and to report our initial experience using this technique in a Hungarian cohort. Method: Between 15 October 2020 and 21 March 2021, patients who underwent endovascular aortic reconstruction were prospectively and consecutively collected. Patients who were deemed suitable for common femoral artery percutaneous access were enrolled to the study. Technical success, access-site complications and risk factors were analyzed. Results: A total of 43 patients underwent endovascular aortic reconstruction during the study period, of whom 38 were deemed feasible for percutaneous repair. Dominantly infrarenal aortic aneurysms were treated (n = 26, 68.4%). After ultrasound-guided access, suture-mediated devices were used 2 (1-4) per artery (median, min-max) for closure. Technical success was reported in 37 out of 38 cases (97.4%). Access site complication was reported in 3 (7.9%) cases. The mean (± SD) in-hospital stay was 4.9 (± 1.7) days. Out of the 3 cases, 1 required intraoperative femoral cut-down. Sheath-size larger than 18 Fr (1.26, 0.09-17.75, 0.862) and body mass index (1.17, 0.923-1.5, 0.19) were positively associated with access site complication but no significant correlation was reported (OR, 95% CI, p-value). However, in patients with larger than 30 kg/m2 body mass index (n = 12), access-related complication was significantly higher than in smaller patients (p = 0.008). Conclusion: Percutaneous endovascular aortic repair is a promising and safe option that has a high technical success rate in patients deemed eligible for common femoral artery access. Orv Hetil. 2022; 163(33): 1318-1323.
MeSH term(s)	Aortic Aneurysm ; Blood Vessel Prosthesis Implantation/adverse effects ; Cohort Studies ; Femoral Artery/surgery ; Humans
Language	English
Publishing date	2022-08-14
Publishing country	Hungary
Document type	Journal Article
ZDB-ID	123879-6
ISSN	1788-6120 ; 0030-6002
ISSN (online)	1788-6120
ISSN	0030-6002
DOI	10.1556/650.2022.32568
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Article ; Online: Catheter-directed thrombolysis in acute critical limb ischemia

Zatykó, Dóra Zoé / Pomozi, Enikő / Pataki, Ákos / Szeberin, Zoltán

Orvosi hetilap

2022 Volume 163, Issue 11, Page(s) 424–430

Title translation	Akut, kritikus alsó végtagi ischaemia kezelése katéteres thrombolysissel.
MeSH term(s)	Catheters ; Chronic Limb-Threatening Ischemia ; Humans ; Male ; Middle Aged ; Retrospective Studies ; Thrombolytic Therapy/methods ; Treatment Outcome
Language	Hungarian
Publishing date	2022-03-13
Publishing country	Hungary
Document type	Journal Article
ZDB-ID	123879-6
ISSN	1788-6120 ; 0030-6002
ISSN (online)	1788-6120
ISSN	0030-6002
DOI	10.1556/650.2022.32376
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Article: Unusual hybrid repair of a thoracoabdominal and mesenteric aneurysm with aberrant right hepatic artery.

Vecsey-Nagy, Milán / Szeberin, Zoltán / Csobay-Novák, Csaba

Journal of vascular surgery cases and innovative techniques

2021 Volume 7, Issue 3, Page(s) 458–461

Abstract: Hybrid approaches for the treatment of thoracoabdominal aortic aneurysms that combine visceral debranching and endovascular repair are feasible alternatives to open surgery for certain high-risk patients. A 70-year-old man was admitted with a rapidly ... ...

Abstract	Hybrid approaches for the treatment of thoracoabdominal aortic aneurysms that combine visceral debranching and endovascular repair are feasible alternatives to open surgery for certain high-risk patients. A 70-year-old man was admitted with a rapidly expanding thoracoabdominal aneurysm involving the superior mesenteric artery, associated with an aberrant hepatic artery. An iliovisceral debranching was performed, followed by the endovascular repair of the thoracoabdominal aorta with a standard thoracic device. The ostial aneurysm was excluded by retrograde implantation of a covered stent from the superior mesenteric artery. Such approach can be considered as a viable alternative in the management of complex thoracoabdominal aneurysms.
Language	English
Publishing date	2021-06-04
Publishing country	United States
Document type	Case Reports
ISSN	2468-4287
ISSN	2468-4287
DOI	10.1016/j.jvscit.2021.05.016
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Article: The impact of increasing saline flush volume to reduce the amount of residual air in the delivery system of aortic prostheses-a randomized controlled trial.

Szentiványi, András / Borzsák, Sarolta / Vecsey-Nagy, Milán / Süvegh, András / Hüttl, Artúr / Fontanini, Daniele Mariastefano / Szeberin, Zoltán / Csobay-Novák, Csaba

Frontiers in cardiovascular medicine

2024 Volume 11, Page(s) 1335903

Abstract: Background: Air embolism is a known risk during thoracic endovascular aortic repair (TEVAR) and is associated with an incomplete deairing of the delivery system despite the saline lavage recommended by the instructions for use (IFU). As the delivery ... ...

Abstract	Background: Air embolism is a known risk during thoracic endovascular aortic repair (TEVAR) and is associated with an incomplete deairing of the delivery system despite the saline lavage recommended by the instructions for use (IFU). As the delivery systems are identical and residual air remains frequently in the abdominal aortic aneurysm sac, endovascular aortic repair (EVAR) can be used to examine the effectiveness of deairing maneuvers. We aimed to evaluate whether increasing the flush volume can result in a more complete deairing. Methods: Patients undergoing EVAR were randomly assigned according to flushing volume (Group A, 1× IFU; Group B, 4× IFU). The Terumo Aortic Anaconda and Treo and Cook Zenith Alpha Abdominal stent grafts were randomly implanted in equal distribution (10-10-10). The quantity of air trapped in the aneurysm sac was measured using a pre-discharge computed tomography angiography (CTA). Thirty patients were enrolled and equally distributed between the two groups, with no differences observed in any demographic or anatomical factors. Results: The presence of air was less frequent in Group A compared to that in Group B [7 (47%) vs. 13 (87%), Discussion: These findings suggest that increased flushing volume is associated with a higher amount of trapped air; thus, following the IFU might be associated with a reduced risk of air embolization. Furthermore, significant differences were identified between devices in terms of the amount of trapped air. Clinical trial registration: [NCT04909190], [ClinicalTrials.gov].
Language	English
Publishing date	2024-03-22
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2781496-8
ISSN	2297-055X
ISSN	2297-055X
DOI	10.3389/fcvm.2024.1335903
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Article ; Online: Hasi aorta aneurysma másodlagos rupturáinak kezelése orvos által módosított fenesztrált grafttal, endocsavarozással, majd nyitott műtéttel.

Hüttl, Artúr / Nagy, Zsuzsa / Szentiványi, András / Szeberin, Zoltán / Csobay-Novák, Csaba

Orvosi hetilap

2023 Volume 164, Issue 36, Page(s) 1426–1431

Abstract: Secondary rupture is a late complication of endovascular aneurysm repair (EVAR). Open surgery is a technically feasible treatment option in most cases, however, late conversion carries a significant risk of morbidity and mortality, as it usually requires ...

Title translation	Secondary ruptures of an abdominal aortic aneurysm treated with a physician-modified fenestrated endograft, endoanchors and finally with open repair.
Abstract	Secondary rupture is a late complication of endovascular aneurysm repair (EVAR). Open surgery is a technically feasible treatment option in most cases, however, late conversion carries a significant risk of morbidity and mortality, as it usually requires at least partial explantation of the in situ device, which is of major concern especially if suprarenal fixation is present. Endovascular treatment of these cases is usually challenging, especially since the custom-made devices that are often needed are not readily available but having a production time of several weeks. To overcome this limitation, physician-modified stent grafts are getting accepted to treat such urgent cases. We present the case of a patient receiving EVAR who later experienced two ruptures, treated first with a physician-modified endograft and adjunctive endoanchoring, later with open ligation of the lumbar arteries. Orv Hetil. 2023; 164(36): 1426-1431.
MeSH term(s)	Humans ; Aortic Aneurysm, Abdominal/surgery ; Blood Vessel Prosthesis Implantation ; Endovascular Procedures ; Stents ; Physicians
Language	Hungarian
Publishing date	2023-09-10
Publishing country	Hungary
Document type	Case Reports ; English Abstract ; Journal Article
ZDB-ID	123879-6
ISSN	1788-6120 ; 0030-6002
ISSN (online)	1788-6120
ISSN	0030-6002
DOI	10.1556/650.2023.32856
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Article: In situ

Banga, Peter / Legeza, Peter / Szeberin, Zoltán

Interventional medicine & applied science

2020 Volume 11, Issue 2, Page(s) 122–124

Abstract: Objectives: Treatment of paravisceral aortic infections poses several challenges because standard therapy with excision of all infected tissues and extraanatomic reconstruction is frequently not possible without jeopardizing visceral perfusion. : ... ...

Abstract	Objectives: Treatment of paravisceral aortic infections poses several challenges because standard therapy with excision of all infected tissues and extraanatomic reconstruction is frequently not possible without jeopardizing visceral perfusion. Methods: Medical documentation and CT angiography studies were retrospectively reviewed for a patient in a tertiary care center. Results: A 62-year-old male patient presented with an infected pseudoaneurysm of the paravisceral aorta at the level of the celiac artery. He had previously undergone multiple orthopedic surgical interventions and developed methicillin-resistant Conclusion: In case of infected aortic pseudoaneurysm, the use of cryopreserved aortic allograft is a reliable choice for reconstruction of the aorta.
Language	English
Publishing date	2020-02-14
Publishing country	Hungary
Document type	Case Reports
ZDB-ID	2573851-3
ISSN	2061-5094 ; 2061-1617
ISSN (online)	2061-5094
ISSN	2061-1617
DOI	10.1556/1646.11.2019.11
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Article ; Online: Comparison of arterial and venous allograft bypass in chronic limb-threatening ischemia.

Garbaisz, Dávid / Osztrogonácz, Péter / Boros, András Mihály / Hidi, László / Sótonyi, Péter / Szeberin, Zoltán

PloS one

2022 Volume 17, Issue 10, Page(s) e0275628

Abstract: Introduction: Femoro-popliteal bypass with autologous vascular graft is a key revascularization method in chronic limb-threatening ischemia (CLTI). However, the lack of suitable autologous conduit may occur in 15-45% of the patients, necessitating the ... ...

Abstract	Introduction: Femoro-popliteal bypass with autologous vascular graft is a key revascularization method in chronic limb-threatening ischemia (CLTI). However, the lack of suitable autologous conduit may occur in 15-45% of the patients, necessitating the implantation of prosthetic or allogen grafts. Only little data is available on the outcome of allograft use in CLTI. Aims: Our objective were to evaluate the long term results of infrainguinal allograft bypass surgery in patients with chronic limb-threatening ischemia (CLTI) and compare the results of arterial and venous allografts. Methods: Single center, retrospective study analysing the outcomes of infrainguinal allograft bypass surgery in patients with CLTI between January 2007 and December 2017. Results: During a 11-year period, 134 infrainguinal allograft bypasses were performed for CLTI [91 males (67.9%)]. Great saphenous vein (GSV) was implanted in 100 cases, superficial femoral artery (SFA) was implanted in 34 cases. Early postoperative complications appeared in 16.4% of cases and perioperative mortality (<30 days) was 1.4%. Primary patency at one, three and five years was 59%, 44% and 41%, respectively, while secondary patency was 60%, 45% and 41%, respectively. Primary patency of the SFA allografts was significantly higher than GSV allografts (1 year: SFA: 84% vs. GSV: 51% p = 0,001; 3 years: SFA: 76% vs. GSV: 32% p = 0,001; 5 years: SFA: 71% vs. GSV: 30% p = 0.001). Both primary and secondary patency of SFA allograft implanted in below-knee position were significantly higher than GSV bypasses (p = 0.0006; p = 0.0005, respectively). Limb salvage at one, three and five years following surgery was 74%, 64% and 62%, respectively. Long-term survival was 53% at 5 years. Conclusion: Allograft implantation is a suitable method for limb salvage in CLTI. The patency of arterial allograft is better than venous allograft patency, especially in below-knee position during infrainguinal allograft bypass surgery.
MeSH term(s)	Male ; Humans ; Ischemia ; Vascular Patency ; Chronic Limb-Threatening Ischemia ; Retrospective Studies ; Saphenous Vein/surgery ; Limb Salvage ; Allografts ; Treatment Outcome ; Peripheral Arterial Disease ; Risk Factors
Language	English
Publishing date	2022-10-27
Publishing country	United States
Document type	Journal Article
ZDB-ID	2267670-3
ISSN	1932-6203 ; 1932-6203
ISSN (online)	1932-6203
ISSN	1932-6203
DOI	10.1371/journal.pone.0275628
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