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Article: Medicaments, Therapies and their Prices in the Inventary of the Family Batthyány 1650-1654.

Toth, Mária

2018 Volume 62, Issue 1-4, Page(s) 155–184

Abstract: Author - after this short introduction and analysis - published below the pharmaceutical bills sent by various pharmacists for Count Adam Batthyány and for his wife Katalin Aurora For- mentini during the period 1650-1654. Based on these bills author ... ...

Title translation	Patikaszerek, gyógymódok és áraik a Batthyány család inventáriumának irataiból 1650-1654.
Abstract	Author - after this short introduction and analysis - published below the pharmaceutical bills sent by various pharmacists for Count Adam Batthyány and for his wife Katalin Aurora For- mentini during the period 1650-1654. Based on these bills author identifies the illnesses to be cured, the names of pharmacists and the medicaments made by them, including their prices as well. The carefully written bills recorded the names of the medicaments used both in German and Latin. The prices partly proved to be astonishingly high, so author concludes that services of pharmacists that time were utilized exclusively by the rich. Analysing the bills we can identify the illnesses of the Batthyány family and also those of the Turks imprisoned in their castle, whose curing served the economic interest of the count.
MeSH term(s)	Famous Persons ; Fees, Pharmaceutical/history ; History, 17th Century ; Humans ; Hungary
Language	Hungarian
Publishing date	2018-08-01
Publishing country	Hungary
Document type	Historical Article ; Journal Article
ZDB-ID	443122-4
ISSN	0010-3551
ISSN	0010-3551
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Article ; Online: Comprehensive Comparison of Baculoviral and Plasmid Gene Delivery in Mammalian Cells.

Toth, Maria / Reithofer, Manuel / Dutra, Gregory / Pereira Aguilar, Patricia / Dürauer, Astrid / Grabherr, Reingard

Viruses

2024 Volume 16, Issue 3

Abstract: 1) Recombinant protein production in mammalian cells is either based on transient transfection processes, often inefficient and underlying high batch-to-batch variability, or on laborious generation of stable cell lines. Alternatively, BacMam, a ... ...

Abstract	(1) Recombinant protein production in mammalian cells is either based on transient transfection processes, often inefficient and underlying high batch-to-batch variability, or on laborious generation of stable cell lines. Alternatively, BacMam, a transduction process using the baculovirus, can be employed. (2) Six transfecting agents were compared to baculovirus transduction in terms of transient and stable protein expression characteristics of the model protein ACE2-eGFP using HEK293-6E, CHO-K1, and Vero cell lines. Furthermore, process optimization such as expression enhancement using sodium butyrate and TSA or baculovirus purification was assessed. (3) Baculovirus transduction efficiency was superior to all transfection agents for all cell lines. Transduced protein expression was moderate, but an 18-fold expression increase was achieved using the enhancer sodium butyrate. Ultracentrifugation of baculovirus from a 3.5 L bioreactor significantly improved the transduction efficiency and protein expression. Stable cell lines were obtained with each baculovirus transduction, yet stable cell line generation after transfection was highly unreliable. (4) This study demonstrated the superiority of the BacMam platform to standard transfections. The baculovirus efficiently transduced an array of cell lines both transiently and stably and achieved the highest efficiency for all tested cell lines. The feasibility of the scale-up of baculovirus production was demonstrated and the possibility of baculovirus purification was successfully explored.
MeSH term(s)	Animals ; Humans ; Butyric Acid ; HEK293 Cells ; Genetic Vectors/genetics ; Baculoviridae/genetics ; Baculoviridae/metabolism ; Plasmids/genetics ; Mammals
Chemical Substances	Butyric Acid (107-92-6)
Language	English
Publishing date	2024-03-10
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2516098-9
ISSN	1999-4915 ; 1999-4915
ISSN (online)	1999-4915
ISSN	1999-4915
DOI	10.3390/v16030426
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Urbanization reduces gut bacterial microbiome diversity in a specialist ground beetle, Carabus convexus.

Magura, Tibor / Mizser, Szabolcs / Horváth, Roland / Tóth, Mária / Likó, István / Lövei, Gábor L

Molecular ecology

2024 Volume 33, Issue 4, Page(s) e17265

Abstract: Urbanization is rapidly shaping and transforming natural environments, creating networks of modified land types. These urbanization-driven modifications lead to local extinctions of several species, but the surviving ones also face numerous novel ... ...

Abstract	Urbanization is rapidly shaping and transforming natural environments, creating networks of modified land types. These urbanization-driven modifications lead to local extinctions of several species, but the surviving ones also face numerous novel selection pressures, including exposure to pollutants, habitat alteration, and shifts in food availability and diversity. Based on the assumption that the environmental pool of microorganisms is reduced in urban habitats due to habitat alteration, biodiversity loss, and pollution, we hypothesized that the diversity of bacterial microbiome in digestive tracts of arthropods would be lower in urban than rural habitats. Investigating the gut bacterial communities of a specialist ground beetle, Carabus convexus, in forested rural versus urban habitats by next generation high-throughput sequencing of the bacterial 16S rRNA gene, we identified 3839 bacterial amplicon sequence variants. The composition of gut bacterial samples did not significantly differ by habitat (rural vs. urban), sex (female vs. male), sampling date (early vs. late spring), or their interaction. The microbiome diversity (evaluated by the Rényi diversity function), however, was higher in rural than urban adults. Our findings demonstrate that urbanization significantly reduced the diversity of the gut bacterial microbiome in C. convexus.
MeSH term(s)	Animals ; Male ; Female ; Urbanization ; Gastrointestinal Microbiome/genetics ; Coleoptera/genetics ; RNA, Ribosomal, 16S/genetics ; Ecosystem ; Biodiversity ; Microbiota ; Bacteria/genetics
Chemical Substances	RNA, Ribosomal, 16S
Language	English
Publishing date	2024-01-12
Publishing country	England
Document type	Journal Article
ZDB-ID	1126687-9
ISSN	1365-294X ; 0962-1083
ISSN (online)	1365-294X
ISSN	0962-1083
DOI	10.1111/mec.17265
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Urban Individuals of Three Rove Beetle Species Are Not More Exploratory or Risk-Taking Than Rural Conspecifics

Magura, Tibor / Horváth, Roland / Mizser, Szabolcs / Tóth, Mária / Nagy, Dávid D. / Csicsek, Réka / Balla, Emőke / Lövei, Gábor L.

Insects. 2022 Aug. 22, v. 13, no. 8

2022

Abstract: Urbanization is creating changes in environmental and habitat conditions, as well as creating disturbance and threats to urban-associated species. Some traits, such as high exploratory and risk-taking behavior, are beneficial to allow colonization of ... ...

Abstract	Urbanization is creating changes in environmental and habitat conditions, as well as creating disturbance and threats to urban-associated species. Some traits, such as high exploratory and risk-taking behavior, are beneficial to allow colonization of urban habitats and coping with urbanization-derived pressures. In this study the exploratory and risk-taking behavior of rural and urban individuals of three forest-associated rove beetle species were tested during their main reproductive period by five frequently used behavioral measures. Individuals of all studied species were similarly ranked by all behavioral measures, indicating that the studied rove beetles responded consistently in the different contexts. However, the behavior of beetles was consistent over time for all/most studied species only by using two measures of exploratory behavior. These provide evidence for the existence of the exploratory dimension of personality in rove beetles. We found a higher exploratory behavior in males than females in Ocypus nitens which can be explained by the active searching of males for mating partners. There were no urbanization-related differences in the exploratory behavior of individuals, suggesting that behavioral changes (being more exploratory) may not yield additional fitness benefits in these rove beetle species with good dispersal capacity.
Keywords	Staphylinidae ; habitats ; personality ; risk behavior ; urbanization
Language	English
Dates of publication	2022-0822
Publishing place	Multidisciplinary Digital Publishing Institute
Document type	Article
ZDB-ID	2662247-6
ISSN	2075-4450
ISSN	2075-4450
DOI	10.3390/insects13080757
Database	NAL-Catalogue (AGRICOLA)

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Article ; Online: SPECIFIC APPROACHES OF PRODUCTIVITY IN SERVICES. VALUES OF SEVERAL COMPARATIVE INDICATORS

Jivan Alexandru / Toth Maria

Annals of the University of Oradea : Economic Science, Vol 22, Iss 1, Pp 465-

2013 Volume 471

Abstract: The paper proposes a synthesis of several specific approaches of productivity in services, in order to provide a better argued theoretical basis for a realistic assessment of the values of several comparative indicators. From a conceptual point of view, ... ...

Abstract	The paper proposes a synthesis of several specific approaches of productivity in services, in order to provide a better argued theoretical basis for a realistic assessment of the values of several comparative indicators. From a conceptual point of view, the paper will take as a base some definitions of productivity as a quantitative and industrial indicator, revealing certain aspects that need a widening of the area of approach, in the purpose of being suitable for immaterial activities. Based on the brief analysis of productivity, performance and servicity indicators, the research establishes correlations between them in the immaterial field. Elder and, as well, most recent analyses found in the field literature are used, from most rigorous sources, and they are supplemented with own approaches; such approaches ore pointing out several most specific features that are specially set for services and intellect-intensive activities. Technical and financial aspects of common productivity are taken into account, as well as performance in realising various goals, non-economic here included, and the service components, in a complex approach. The presentation focus on nuance features in the quoted references, in the purpose of a fine defining of the indictors and approaches. Specific particularization is achieved based on the literature. Methodologically, the paper is approaching in an unorthodox manner, the plus of value issued from the human activity, i.e. being in a view coming from a fine analysis of the service performed by any economic activity, in a market system. The conceptual importance of these comparative indicators is concisely highlighted, and it consists mainly in the opening that can become a useful ground for practical applicative analyses, which actually are proposed in the future developments of the topic. The research results reveal the relationship between these comparative indicators as well as some conceptual differences between them. Their application can be made for material and immaterial economic activities, at different levels of economic entities concerned.
Keywords	productivity ; performance ; services ; Social Sciences ; H ; Economic theory. Demography ; HB1-3840
Publishing date	2013-07-01T00:00:00Z
Publisher	University of Oradea
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article: Are There Personality Differences between Rural vs. Urban-Living Individuals of a Specialist Ground Beetle, Carabus convexus?

Magura, Tibor / Mizser, Szabolcs / Horváth, Roland / Nagy, Dávid D. / Tóth, Mária / Csicsek, Réka / Lövei, Gábor L.

Insects. 2021 July 15, v. 12, no. 7

2021

Abstract: The world-wide, rapid urbanization is leading to substantial changes in environmental and habitat conditions. These changes, as well as disturbances accompanying urbanization have considerable effects at various levels of the biological organization on ... ...

Abstract	The world-wide, rapid urbanization is leading to substantial changes in environmental and habitat conditions. These changes, as well as disturbances accompanying urbanization have considerable effects at various levels of the biological organization on wildlife. Understanding behavioral responses to such changes is essential for identifying which organisms may successfully adapt to the altered conditions. In this study, individuals of a forest specialist ground beetle, Carabus convexus, from rural and urban forest patches were tested for their exploratory and risk-taking behavior. Beetles responded consistently in the different contexts; furthermore, by behaving consistently over time, demonstrated that they had personalities. Agglomerative cluster analysis identified two groups of behavioral traits: the exploratory and the risk-taking dimension of personality. Urban females were significantly more exploratory than urban males which can be an adaptation to find high quality food needed to mature eggs in urban habitats, as well as to select favorable microsites for oviposition. Moreover, urban females and males showed more risk-taking behavior than rural females. Urban beetles with more risk-taking behavior may be better able to cope with frequent urbanization-driven disturbance events.
Keywords	Carabidae ; cluster analysis ; habitats ; oviposition ; personality ; risk behavior ; urban forests ; urbanization ; wildlife
Language	English
Dates of publication	2021-0715
Publishing place	Multidisciplinary Digital Publishing Institute
Document type	Article
ZDB-ID	2662247-6
ISSN	2075-4450
ISSN	2075-4450
DOI	10.3390/insects12070646
Database	NAL-Catalogue (AGRICOLA)

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Article: Differences in Life History Traits in Rural vs. Urban Populations of a Specialist Ground Beetle, Carabus convexus

Magura, Tibor / Mizser, Szabolcs / Horváth, Roland / Nagy, Dávid D. / Tóth, Mária / Csicsek, Réka / Lövei, Gábor L.

Insects. 2021 June 10, v. 12, no. 6

2021

Abstract: Urbanization is increasing worldwide and causes substantial changes in environmental parameters, generating various kinds of stress on arthropods, with several harmful consequences. We examined a forest specialist ground beetle, Carabus convexus, in ... ...

Abstract	Urbanization is increasing worldwide and causes substantial changes in environmental parameters, generating various kinds of stress on arthropods, with several harmful consequences. We examined a forest specialist ground beetle, Carabus convexus, in forested habitats to evaluate the changes in four important life history traits between rural and urban populations. Analyzing beetles from the overwintered cohort in their first breeding season, we found no significant differences in body length or body mass between the rural and urban individuals. Body condition, judged by fat reserve scores, was similarly poor in both habitats, indicating that beetles were not able to accumulate substantial fat reserves at either habitat. Females with ripe eggs in their ovaries were first captured at the same time in both areas. The number of ripe eggs, however, was significantly higher in females of the low-density urban population (6.13 eggs/female) than in those of the high-density rural population (4.14 eggs/female), indicating density-dependent fecundity. Altered environmental and habitat conditions by urbanization, however, seemed to cause high mortality during egg hatching and/or larval development, preventing the growth of the urban population to the level of rural one.
Keywords	Carabidae ; body condition ; body length ; body weight ; eggs ; fecundity ; females ; forests ; larval development ; life history ; mortality ; rural population ; urban population ; urbanization
Language	English
Dates of publication	2021-0610
Publishing place	Multidisciplinary Digital Publishing Institute
Document type	Article
ZDB-ID	2662247-6
ISSN	2075-4450
ISSN	2075-4450
DOI	10.3390/insects12060540
Database	NAL-Catalogue (AGRICOLA)

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Article: Urban Individuals of Three Rove Beetle Species Are Not More Exploratory or Risk-Taking Than Rural Conspecifics.

Magura, Tibor / Horváth, Roland / Mizser, Szabolcs / Tóth, Mária / Nagy, Dávid D / Csicsek, Réka / Balla, Emőke / Lövei, Gábor L

Insects

2022 Volume 13, Issue 8

Abstract	Urbanization is creating changes in environmental and habitat conditions, as well as creating disturbance and threats to urban-associated species. Some traits, such as high exploratory and risk-taking behavior, are beneficial to allow colonization of urban habitats and coping with urbanization-derived pressures. In this study the exploratory and risk-taking behavior of rural and urban individuals of three forest-associated rove beetle species were tested during their main reproductive period by five frequently used behavioral measures. Individuals of all studied species were similarly ranked by all behavioral measures, indicating that the studied rove beetles responded consistently in the different contexts. However, the behavior of beetles was consistent over time for all/most studied species only by using two measures of exploratory behavior. These provide evidence for the existence of the exploratory dimension of personality in rove beetles. We found a higher exploratory behavior in males than females in
Language	English
Publishing date	2022-08-22
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2662247-6
ISSN	2075-4450
ISSN	2075-4450
DOI	10.3390/insects13080757
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: DIMENSIONS OF HUMAN CAPITAL â€“ SPECIFIC HEALTH APPROACH OF NATIONS CAPITAL

Toth Maria / Jivan Alexandru

Annals of the University of Oradea : Economic Science, Vol 1, Iss 1, Pp 312-

2012 Volume 317

Abstract: The paper proposes sythesizing the most important correlations between the dimensions of human capital, in order to provide a better theoretical basis for assessing realistic valence motivated human resources sustainable development of society. In terms ... ...

Abstract	The paper proposes sythesizing the most important correlations between the dimensions of human capital, in order to provide a better theoretical basis for assessing realistic valence motivated human resources sustainable development of society. In terms of conceptual work based on the fundamental role of health capital and the neglect that often has its problems, especially in developing countries. Based on the review abstract theory of human capital, research establishes correlations between dimensions. It shows the importance of ethical component in professionalism and existence of moral capital rooted in medical ethics. Specific breakdowns of health capital, referring to the health of the population and medical services. The research findings highlight the profound connection between morality and productivity seemingly nonexistent (customized to the case of medical services), about joint economic approaches ignored. It also means that the moral, professional and medical staff working in social capital formation influence the health of a nation.
Keywords	Human capital ; health capital ; medical services ; productivity ; Economic theory. Demography ; HB1-3840 ; Social Sciences ; H ; DOAJ:Economics ; DOAJ:Business and Economics
Subject code	170
Publishing date	2012-07-01T00:00:00Z
Publisher	University of Oradea
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article: Are There Personality Differences between Rural vs. Urban-Living Individuals of a Specialist Ground Beetle,

Magura, Tibor / Mizser, Szabolcs / Horváth, Roland / Nagy, Dávid D / Tóth, Mária / Csicsek, Réka / Lövei, Gábor L

Insects

2021 Volume 12, Issue 7

Abstract	The world-wide, rapid urbanization is leading to substantial changes in environmental and habitat conditions. These changes, as well as disturbances accompanying urbanization have considerable effects at various levels of the biological organization on wildlife. Understanding behavioral responses to such changes is essential for identifying which organisms may successfully adapt to the altered conditions. In this study, individuals of a forest specialist ground beetle,
Language	English
Publishing date	2021-07-15
Publishing country	Switzerland
Document type	Journal Article
ISSN	2075-4450
ISSN	2075-4450
DOI	10.3390/insects12070646
Database	MEDical Literature Analysis and Retrieval System OnLINE

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