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Article ; Online: Four-dimensional speckle tracking echocardiography and fragmented QRS in detection of early left ventricular systolic dysfunction in patients with subclinical hyperthyroidism.

Karaca, Yücel / Karasu, Mehdi / Taşolar, Hakan / Evren, Bahri

2023 Volume 51, Issue 6, Page(s) 939–948

Abstract: Background: Thyroid disorders are associated with many cardiovascular risk factors. The importance of thyroid hormones in the pathophysiology of heart failure is underlined by the European guidelines of the European Society of Cardiology. However, the ... ...

Abstract	Background: Thyroid disorders are associated with many cardiovascular risk factors. The importance of thyroid hormones in the pathophysiology of heart failure is underlined by the European guidelines of the European Society of Cardiology. However, the role of subclinical hyperthyroidism (SCH) in subclinical left ventricular (LV) systolic dysfunction is not entirely clear. Methods: This cross-sectional study included 56 SCH patients and 40 healthy volunteers. The 56 SCH group was divided into two subgroups depending on the presence of fragmented QRS (fQRS). In both groups, left ventricular global area strain (LV-GAS), global radial strain (GRS), global longitudinal strain (GLS), and global circumferential strain (GCS) were obtained with four-dimensional (4D) echocardiography. Results: GAS, GRS, GLS, and GCS values were significantly different in SCH patients and in healthy volunteers. GLS and GAS values were lower in the fQRS+ than in the fQRS- group (-17.06 ± 1.00 vs. -19.08 ± 1.71, p < .001, and -26.61 ± 2.38 vs. -30.61 ± 2.57, p < .001, respectively). ProBNP was positively correlated with LV-GLS (r = 0.278, p = .006) and LV-GAS (r = 0.357, p < .001). Multiple linear regression analysis showed that fQRS was an independent predictor of LV-GAS. Conclusions: 4D strain echocardiography may be helpful for the prediction of early cardiac dysfunction in patients with SCH. The presence of fQRS may be an indicator of subclinical LV dysfunction in SCH.
MeSH term(s)	Humans ; Cross-Sectional Studies ; Ventricular Dysfunction, Left/complications ; Ventricular Dysfunction, Left/diagnostic imaging ; Echocardiography/methods ; Hyperthyroidism/complications ; Hyperthyroidism/diagnostic imaging ; Electrocardiography ; Echocardiography, Three-Dimensional/methods ; Ventricular Function, Left/physiology
Language	English
Publishing date	2023-04-01
Publishing country	United States
Document type	Journal Article
ZDB-ID	189393-2
ISSN	1097-0096 ; 0091-2751
ISSN (online)	1097-0096
ISSN	0091-2751
DOI	10.1002/jcu.23459
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Zs.A 1186: Show issues

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Article ; Online: Attention for insertion of temporary cardiac pacemaker in liver transplant patients.

Ince, Volkan / Tasolar, Hakan / Yilmaz, Sezai

Northern clinics of Istanbul

2021 Volume 8, Issue 5, Page(s) 543–544

Language	English
Publishing date	2021-10-22
Publishing country	Turkey
Document type	Journal Article
ZDB-ID	3031921-3
ISSN	2536-4553 ; 2148-4902
ISSN (online)	2536-4553
ISSN	2148-4902
DOI	10.14744/nci.2020.59354
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Article ; Online: The Effect of Marked Nasal Septal Deviation on Left Ventricular Function and Blood Markers.

Karataş, Mehmet / Taşolar, Hakan

The Journal of craniofacial surgery

2019 Volume 30, Issue 3, Page(s) 803–807

Abstract: Objectives: This study aimed to assess the effect of nasal septoplasty in patients with marked nasal septal deviation (MNSD) on subjective perception of nasal patency, echocardiography, and hematologic parameters.: Methods: Seventy-nine consecutive ... ...

Abstract	Objectives: This study aimed to assess the effect of nasal septoplasty in patients with marked nasal septal deviation (MNSD) on subjective perception of nasal patency, echocardiography, and hematologic parameters. Methods: Seventy-nine consecutive patients (mean age, 29.9 ± 9.7 years; 57 men and 22 women) at least 18 years old were diagnosed as MNSD consistent with presenting symptom of chronic nasal obstruction lasting at least 3 months. Complete blood count measurement to assess mean platelet volume (MPV) and neutrophil to lymphocyte ratio (NLR), the Nasal Obstruction Symptom Evaluation (NOSE) questionnaire, and echocardiography were performed for all patients just before and at postoperative third month of septoplasty. Results: The MPV (0.021), NLR (<0.001), and NOSE (<0.001) were all significantly decreased, and global longitudinal strain (GLS) value (<0.001) were also significantly increased at postoperative third month. Correlation analysis also indicated that ΔNLR was positively correlated with ΔGLS (r = 0.385, P < 0.001), and ΔNOSE (r = 0.436, P < 0.001), and correlated negatively with the ΔMPV (r = -0.302, P = 0.024). ΔGLS was also positively correlated with the ΔNOSE (r = 0.769, P < 0.001). Conclusion: Septoplasty for MNSD could provide not only alleviation of otorhinolaryngologic symptoms but also improvement in subclinical left ventricular systolic dysfunction and decline in MPV and NLR levels.
MeSH term(s)	Adult ; Echocardiography ; Female ; Humans ; Lymphocyte Count ; Male ; Mean Platelet Volume ; Nasal Obstruction/etiology ; Nasal Obstruction/physiopathology ; Nasal Obstruction/surgery ; Nasal Septum/abnormalities ; Nasal Septum/surgery ; Neutrophils ; Postoperative Period ; Prospective Studies ; Rhinoplasty ; Surveys and Questionnaires ; Ventricular Function, Left ; Young Adult
Language	English
Publishing date	2019-01-16
Publishing country	United States
Document type	Journal Article
ZDB-ID	1159501-2
ISSN	1536-3732 ; 1049-2275
ISSN (online)	1536-3732
ISSN	1049-2275
DOI	10.1097/SCS.0000000000005112
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Zs.A 3761: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (2.OG) ab Jg. 2022: Lesesaal (EG)
Zs.MO 175: Show issues

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Article ; Online: Assessment of a New Electrocardiographic Marker for the Diagnosis of Myocardial Infarction With Non-obstructive Coronary Arteries.

Demirelli, Selami / Md, Kemal Abid Tekin / Taşolar, Hakan / Çalapkorur, Bekir / Ergün, Gökhan / Demirci, Erkan

Angiology

2022 Volume 74, Issue 3, Page(s) 288–295

Abstract: Myocardial infarction with non-obstructive coronary arteries (MINOCA) is clinically defined as myocardial infarction in the absence of obstructive atherosclerosis on coronary angiography. Diagnosis may require multiple diagnostic tools in addition to ... ...

Abstract	Myocardial infarction with non-obstructive coronary arteries (MINOCA) is clinically defined as myocardial infarction in the absence of obstructive atherosclerosis on coronary angiography. Diagnosis may require multiple diagnostic tools in addition to standard coronary angiography, including cardiac imaging or provocative tests, according to clinical suspicion. We assessed the usefulness of the DETERMINE (Defibrillators to Reduce Risk by Magnetic Resonance Imaging Evaluation) score for distinguishing patients with MINOCA from those with non-ST segment elevation myocardial infarction with obstructive coronary artery disease (NSTEMI-CAD) in a single-center observational study. The patients were divided into two groups according to coronary angiography findings. The study included 277 patients: 227 with NSTEMI-CAD and 50 with MINOCA. The DETERMINE score (6.1 ± 3.7
MeSH term(s)	Humans ; MINOCA ; Non-ST Elevated Myocardial Infarction/diagnostic imaging ; Non-ST Elevated Myocardial Infarction/complications ; Myocardial Infarction/etiology ; Coronary Artery Disease/diagnostic imaging ; Coronary Artery Disease/complications ; Coronary Angiography/methods ; Coronary Vessels/diagnostic imaging ; Risk Factors
Language	English
Publishing date	2022-04-22
Publishing country	United States
Document type	Observational Study ; Journal Article
ZDB-ID	80040-5
ISSN	1940-1574 ; 0003-3197
ISSN (online)	1940-1574
ISSN	0003-3197
DOI	10.1177/00033197221089373
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Article ; Online: The importance of pulmonary pulse transit time in indicating right ventricular dysfunction and pulmonary arterial stiffness in rheumatoid arthritis.

Ulutas, Zeynep / Tasolar, Hakan / Bayramoglu, Adil / Yigit, Yakup / Kuloglu, Huseyın Emre / Karaca, Yucel / Yolbas, Servet / Hidayet, Siho / Akaycan, Julide

Journal of clinical ultrasound : JCU

2023 Volume 51, Issue 8, Page(s) 1321–1328

Abstract: Subject: Rheumatoid arthritis patients are at risk of developing cardiovascular disease such as right heart failure and pulmonary hypertension (PH). Arterial stiffness can be used to assess pulmonary hemodynamics. Noninvasive approaches can also be used ...

Abstract	Subject: Rheumatoid arthritis patients are at risk of developing cardiovascular disease such as right heart failure and pulmonary hypertension (PH). Arterial stiffness can be used to assess pulmonary hemodynamics. Noninvasive approaches can also be used to assess pulmonary hemodynamics. Recently, there have been reports that pulmonary pulse transit time (PPTT) may also be a useful measure. This study aims to examine the effects of pulmonary hemodynamic alterations on PPTT in RA patients. Methods: Forty RA patients and 40 healthy controls were included in the study. Sociodemographic characteristics, laboratory data, and echocardiographic examinations were performed in both groups. Conventional echocardiographic examination included left and right ventricular systolic and diastolic diameters, right ventricular myocardial performance index (RVMPI), right ventricular diastolic function, estimated pulmonary artery systolic pressure (sPAP), tricuspid annular plane systolic excursion (TAPSE), pulmonary artery stiffness (PAS), and PPTT. Right ventricular diastolic and systolic volumes, right ventricular ejection fraction (RVEF), and right ventricular fractional area change (RVFAC) were determined by four-dimensional echocardiography (4DE). Results: There was no difference between the sPAP values of the patients. RVMPI and PAS were increased in RA patients compared with controls. The PPTT was shortened in RA patients and correlated with RVEF, RVFAC, RVMPI, TAPSE/sPAP, disease duration, and C-reactive protein (CRP). In univariate linear regression analysis, PPTT (p < .001) was thought to be an independent predictor of PAS. RVFAC, disease duration, and PAS were also independent predictors of PPTT. Conclusion: In RA patients, PPTT may be the first evidence of early abnormalities in pulmonary vascular hemodynamics. PPTT and PAS are the values that may predict each other in RA patients. Due to its more practical application, PPTT can be used instead of PAS to assess pulmonary hemodynamics.
Language	English
Publishing date	2023-08-02
Publishing country	United States
Document type	Journal Article
ZDB-ID	189393-2
ISSN	1097-0096 ; 0091-2751
ISSN (online)	1097-0096
ISSN	0091-2751
DOI	10.1002/jcu.23531
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Zs.A 1186: Show issues

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Article ; Online: Effects of Septoplasty on Tp-e Interval and Tp-e/QT Ratio in Patients With Nasal Septal Deviation.

Taşolar, Hakan / Karataş, Mehmet / Demiröz Aslan, Duygu

The Journal of craniofacial surgery

2019 Volume 31, Issue 1, Page(s) 91–94

Abstract: Objectives: There are multiple nasal airway pathologies leading to upper airway obstruction, and one of the most common ones is nasal septum deviation (NSD). Our study aimed to evaluate the effect of nasal septal surgery in patients with NSD on ... ...

Abstract	Objectives: There are multiple nasal airway pathologies leading to upper airway obstruction, and one of the most common ones is nasal septum deviation (NSD). Our study aimed to evaluate the effect of nasal septal surgery in patients with NSD on ventricular arrhythmogenesis using the novel electrocardiographic parameters, Tp-e interval, and Tp-e/QT ratio. Methods: This retrospective cross-sectional study included 102 consecutive patients diagnosed with NSD. All participants completed a validated outcomes instrument (the NOSE scale), echocardiographic and electrocardiographic evaluation before and 3 months after septoplasty. The degree of nasal septal deviation was evaluated with the Dreher classification. Results: All of the electrocardiography parameters (except heart rate and QTmin) were significantly decreased with the septoplasty operation. Electrocardiographic parameters have significantly decreased especially in marked NSD patients. (Δ = difference between the preoperative and postoperative values) ΔNOSE was positively correlated both ΔcTp-e (r = 0.348, P < .001) and ΔcTp-e/QT values (r = 0.536, P < .001). Conclusion: Consequently, marked NSD was associated with increased risk of arrhythmogenesis, which were too much improved after septoplasty. So, treatment of especially marked NSD not only reduces otolaryngological complaints, but also leads to improvement of ventricular repolarization parameters.
MeSH term(s)	Adult ; Cross-Sectional Studies ; Electrocardiography ; Female ; Heart Rate ; Humans ; Male ; Nasal Septum/surgery ; Nose Deformities, Acquired/surgery ; Postoperative Period ; Retrospective Studies ; Rhinoplasty/adverse effects ; Young Adult
Language	English
Publishing date	2019-08-31
Publishing country	United States
Document type	Journal Article
ZDB-ID	1159501-2
ISSN	1536-3732 ; 1049-2275
ISSN (online)	1536-3732
ISSN	1049-2275
DOI	10.1097/SCS.0000000000005890
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Zs.A 3761: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (2.OG) ab Jg. 2022: Lesesaal (EG)
Zs.MO 175: Show issues

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Article ; Online: Left ventricular myocardial performance index in prediabetic patients without coronary artery disease.

Askin, Lutfu / Cetin, Mustafa / Tasolar, Hakan / Akturk, Erdal

Echocardiography (Mount Kisco, N.Y.)

2018 Volume 35, Issue 4, Page(s) 445–449

Abstract: Introduction: Prediabetes is a high-risk condition for diabetes mellitus type 2, which is an important public health issue. The myocardial performance index (MPI) is a noninvasive Doppler measurement of global ventricular function. We evaluated the MPI ... ...

Abstract	Introduction: Prediabetes is a high-risk condition for diabetes mellitus type 2, which is an important public health issue. The myocardial performance index (MPI) is a noninvasive Doppler measurement of global ventricular function. We evaluated the MPI and left ventricular (LV) function in prediabetic patients who did not have coronary artery disease. Methods: In total, 80 prediabetics (34 females and 46 males) and an equal number of sex-matched healthy volunteers (35 females and 45 males) were enrolled prospectively. All subjects underwent laboratory analyses and echocardiographic examinations, including MPI measurements. Results: There was a moderate increase in MPI between healthy controls and prediabetics (P < .001). Prediabetes was strongly associated with MPI (r = .553, P < .001). We found that MPI was associated with prediabetes on multivariate logistic regression analysis (Odds Ratio (OR) = 1.967, 95% confidence interval [CI] = 1.574-2.459, P < .001). Conclusions: The results of this study show that systolic functions and LV diastolic parameters were adversely affected in prediabetic patients. Prediabetes is closely associated with subclinical LV systolic and diastolic dysfunction as assessed by MPI.
MeSH term(s)	Coronary Artery Disease ; Diastole ; Echocardiography/methods ; Female ; Heart Ventricles/diagnostic imaging ; Heart Ventricles/physiopathology ; Humans ; Male ; Middle Aged ; Prediabetic State/complications ; Prediabetic State/physiopathology ; Prospective Studies ; Systole ; Ventricular Dysfunction, Left/complications ; Ventricular Dysfunction, Left/diagnostic imaging ; Ventricular Dysfunction, Left/physiopathology ; Ventricular Function, Left
Language	English
Publishing date	2018-02-04
Publishing country	United States
Document type	Journal Article
ZDB-ID	843645-9
ISSN	1540-8175 ; 0742-2822
ISSN (online)	1540-8175
ISSN	0742-2822
DOI	10.1111/echo.13822
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Zs.A 2170: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (1.OG) ab Jg. 2022: Lesesaal (EG)
Zs.MO 359: Show issues

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Article ; Online: Author`s Reply.

Hidayet, Şıho / Demir, Vahit / Turan, Yasar / Gurel, Gulhan / Taşolar, Hakan

Anatolian journal of cardiology

2019 Volume 22, Issue 5, Page(s) 279–280

MeSH term(s)	Behcet Syndrome ; Humans
Language	English
Publishing date	2019-11-01
Publishing country	Turkey
Document type	Letter ; Comment
ZDB-ID	2278670-3
ISSN	2149-2271 ; 2149-2263
ISSN (online)	2149-2271
ISSN	2149-2263
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Article ; Online: Left ventricular myocardial performance index in prehypertensive patients with normal coronary arteries.

Yaşar, Erdoğan / Taşolar, Hakan / Açikgöz, Nusret

Blood pressure monitoring

2017 Volume 22, Issue 3, Page(s) 149–153

Abstract: Objectives: Prehypertension, which may be the precursor of hypertension, is an important public health problem in the community. Myocardial performance index (MPI) is a noninvasive Doppler measurement of global ventricular function. Thus, our aim was to ...

Abstract	Objectives: Prehypertension, which may be the precursor of hypertension, is an important public health problem in the community. Myocardial performance index (MPI) is a noninvasive Doppler measurement of global ventricular function. Thus, our aim was to evaluate left ventricule (LV) functions with the MPI in prehypertensive patients with normal coronary artery angiography. Patients and materials: Forty prehypertensive patients (21 women and 19 men), with blood pressures between 120/80 and 139/89 mmHg, and 40 normotensive controls (18 women and 22 men), with blood pressures under 120/80 mmHg, were included in the study. Patient population comprised those who underwent coronary angiography because of typical angina and had normal coronary arteries. The MPI was calculated and compared between the two groups. Results: No statistically significant differences were found between the two groups in terms of age, sex, or other demographic characteristics (P>0.05). Moreover, LV ejection fraction, late diastolic flow, deceleration time, isovolumetric contraction time, and ejection time values were not significantly different between the two groups (P>0.05). However, early diastolic mitral inflow velocity, E/A ratio, isovolumetric relaxation, and MPI were all significantly higher in the patient group than in the control group. Conclusion: The MPI was increased in prehypertensive patients. This result demonstrates that LV diastolic and systolic functions may be negatively affected in patients with prehypertension. The advantages of our method are as follows: it is simple, it does not demand special equipment, and it is not time consuming.
Language	English
Publishing date	2017-06
Publishing country	England
Document type	Journal Article
ZDB-ID	1324472-3
ISSN	1473-5725 ; 1359-5237
ISSN (online)	1473-5725
ISSN	1359-5237
DOI	10.1097/MBP.0000000000000248
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Zs.A 4626: Show issues

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Article ; Online: Comparison of the Predictive Roles of Risk Scores of In-Hospital Major Adverse Cardiovascular Events in Patients with Non-ST Elevation Myocardial Infarction Undergoing Percutaneous Coronary Intervention.

Aktürk, Erdal / Aşkın, Lütfü / Taşolar, Hakan / Türkmen, Serdar / Kaya, Hakan

Medical principles and practice : international journal of the Kuwait University, Health Science Centre

2018 Volume 27, Issue 5, Page(s) 459–465

Abstract: Objective: We evaluated the relationship between various risk scores (SYNTAX score [SS], SYNTAX score-II [SS-II], thrombolysis in myocardial infarction [TIMI] risk scores, and Global Registry of Acute Coronary Events [GRACE] risk scores) and major ... ...

Abstract	Objective: We evaluated the relationship between various risk scores (SYNTAX score [SS], SYNTAX score-II [SS-II], thrombolysis in myocardial infarction [TIMI] risk scores, and Global Registry of Acute Coronary Events [GRACE] risk scores) and major adverse cardiovascular events (MACE) in non-ST elevation myocardial infarction (NSTEMI) patients undergoing percutaneous coronary intervention (PCI). Subjects and methods: The study population were selected from among 589 patients who underwent coronary angiography with a diagnosis of NSTEMI. TIMI and GRACE risk scores were calculated. SS and SS-II were calculated in all patients, and points were added according to the predefined algorithm, taking into account the other 6 clinical variables being monitored (age, sex, left ventricular ejection fraction, creatinine clearance, chronic obstructive pulmonary disease, and peripheral artery disease). Patients were classified into tertile 1 (SS < 22), tertile 2 (SS 23-32), and tertile 3 (SS > 32). Results: The group with high SS-II for PCI values in the risk scores were observed from tertile 1 to tertile 3 (from 25.0 ± 7.7 to 31.6 ± 9.4, p < 0.001, respectively). The SS-II score in patients with PCI was an independent predictor of MACE, in-hospital mortality, nonfatal myocardial infarction, and stent thrombosis (OR 1.082, 95% CI 1.036-1.131, p < 0.001). The overall MACE, in-hospital mortality, and nonfatal myocardial infarction rates were significantly higher in the high SS-II for PCI group (p < 0.001). Conclusion: TIMI and GRACE risk scores were able to predict MACE. In addition to these, SS-II was also able to predict in-hospital mortality, nonfatal myocardial infarction, and stent thrombosis.
MeSH term(s)	Adult ; Aged ; Aged, 80 and over ; Coronary Angiography ; Cross-Sectional Studies ; Decision Support Systems, Clinical ; Female ; Hospital Mortality ; Hospitals ; Humans ; Logistic Models ; Male ; Middle Aged ; Myocardial Infarction/mortality ; Non-ST Elevated Myocardial Infarction/complications ; Percutaneous Coronary Intervention ; Peripheral Arterial Disease ; Predictive Value of Tests ; Pulmonary Disease, Chronic Obstructive ; Risk Assessment/methods ; Risk Factors ; Severity of Illness Index ; Thrombosis/complications ; Thrombosis/epidemiology ; Turkey/epidemiology
Language	English
Publishing date	2018-04-19
Publishing country	Switzerland
Document type	Comparative Study ; Journal Article ; Observational Study
ZDB-ID	645108-1
ISSN	1423-0151 ; 1011-7571
ISSN (online)	1423-0151
ISSN	1011-7571
DOI	10.1159/000489399
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