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  1. Article ; Online: Patterns of pathologically confirmed metastasis to bone in Near East population.

    Flaifel, Abdallah / Tabaja, Farah / Bannoura, Sami / Loya, Asif / Mushtaq, Sajid / Khalifeh, Ibrahim

    Cancer epidemiology

    2018  Volume 54, Page(s) 7–11

    Abstract: Background: Metastatic tumors to bone constitute the majority of bone malignancies. The site of metastasis to bone and the prognosis depend chiefly on the primary tumor. Despite all the advances in diagnostic techniques, identifying the primary tumor ... ...

    Abstract Background: Metastatic tumors to bone constitute the majority of bone malignancies. The site of metastasis to bone and the prognosis depend chiefly on the primary tumor. Despite all the advances in diagnostic techniques, identifying the primary tumor has not improved significantly.
    Methods: A total of 576 cases (Lebanon; n = 306, Pakistan; n = 270) presenting with microscopic evidence of metastasis to bone were reviewed between 1996 and 2016. Clinical and radiologic data were recorded.
    Results: Out of 20 types of primary tumors, unknown primary (38.2%), followed by breast (23.8%), lung (10.4%) and thyroid (4.9%) tumors were the most commonly presenting with bone metastasis. The primary source of the tumor showed significant correlation with the site of metastasis, time lag to metastasis and radiologic presentation (p < 0.001). Interestingly, a significant variation was noted between the 2 observed populations.
    Conclusion: The patterns of pathologically confirmed metastasis to skeletal sites in Near East population showed a special distribution, and variation was even observed between the 2 studied centers. Understanding the biologic variations of the primary tumors in our population may further explain the variation in patterns of metastasis.
    MeSH term(s) Adult ; Aged ; Aged, 80 and over ; Bone Neoplasms/epidemiology ; Bone Neoplasms/pathology ; Bone Neoplasms/secondary ; Female ; Humans ; Lebanon ; Male ; Middle Aged ; Middle East ; Neoplasm Metastasis ; Pakistan ; Prognosis ; Young Adult
    Language English
    Publishing date 2018-03-10
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 2508729-0
    ISSN 1877-783X ; 1877-7821
    ISSN (online) 1877-783X
    ISSN 1877-7821
    DOI 10.1016/j.canep.2018.03.002
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Building Emotional Resilience in Youth in Lebanon: a School-Based Randomized Controlled Trial of the FRIENDS Intervention.

    Maalouf, Fadi T / Alrojolah, Loay / Ghandour, Lilian / Afifi, Rima / Dirani, Leyla Akoury / Barrett, Paula / Nakkash, Rima / Shamseddeen, Wael / Tabaja, Farah / Yuen, Courtney M / Becker, Anne E

    Prevention science : the official journal of the Society for Prevention Research

    2020  Volume 21, Issue 5, Page(s) 650–660

    Abstract: In Lebanon, approximately one in four adolescents suffers from a psychiatric disorder. Alarmingly, 94% of adolescents with a mental disorder have not sought any treatment. This study assessed the effectiveness of an evidence-based school-based universal ... ...

    Abstract In Lebanon, approximately one in four adolescents suffers from a psychiatric disorder. Alarmingly, 94% of adolescents with a mental disorder have not sought any treatment. This study assessed the effectiveness of an evidence-based school-based universal mental health intervention (the FRIENDS program) in reducing depression and anxiety symptoms in middle school students in Lebanon. A total of 280 6th graders aged 11-13 years were recruited from 10 schools in Beirut. Schools were matched on size and tuition and randomly assigned to intervention or control groups. The FRIENDS program was translated into Arabic, adapted, and then implemented by trained mental health professionals during 10 classroom sessions over 3 months. We assessed sociodemographic and relevant psychological symptoms by self-report, using the Scale for Childhood Anxiety and Related Disorders (SCARED), Mood and Feelings Questionnaire (MFQ), and Strengths and Difficulties Questionnaire (SDQ), at baseline. We re-administered these scales at 3 months post-intervention. There was a significant time × group interaction for the SDQ emotional score (p = 0.011) and total MFQ score (p = 0.039) indicating significant improvement in depressive and emotional symptoms in the intervention group. Subgroup analysis by gender showed a significant time × group interaction for the total SCARED score (p = 0.025) in females but not in males (p = 0.137), consistent with a reduction of anxiety symptoms in this stratum of the intervention group as compared with the control group. The FRIENDS program was effective in reducing general emotional and depressive symptoms among middle school students in this Lebanese study population. This intervention provides an opportunity for promoting mental health in Lebanese schools and reducing the treatment gap in mental health care.
    MeSH term(s) Adolescent ; Anxiety Disorders ; Child ; Female ; Health Promotion ; Humans ; Lebanon ; Male ; Resilience, Psychological ; Schools ; Self Report
    Language English
    Publishing date 2020-04-23
    Publishing country United States
    Document type Journal Article ; Randomized Controlled Trial ; Research Support, Non-U.S. Gov't
    ZDB-ID 2251270-6
    ISSN 1573-6695 ; 1389-4986
    ISSN (online) 1573-6695
    ISSN 1389-4986
    DOI 10.1007/s11121-020-01123-5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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