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Article ; Online: Enhanced survival of Lacticaseibacillus rhamnosus in simulated gastrointestinal conditions using layer-by-layer encapsulation.

Chehreara, Afsaneh / Tabandeh, Fatemeh / Otadi, Maryam / Alihosseini, Afshar / Partovinia, Ali

2022 Volume 44, Issue 11, Page(s) 1277–1286

Abstract: Objective: The release behavior of Lacticaseibacillus rhamnosus from single bilayer microcapsules of alginate-chitosan (AC) and its double bilayer (ACAC) was investigated in simulated gastric fluid (SGF) and simulated intestinal fluid (SIF). Methods ... ...

Abstract	Objective: The release behavior of Lacticaseibacillus rhamnosus from single bilayer microcapsules of alginate-chitosan (AC) and its double bilayer (ACAC) was investigated in simulated gastric fluid (SGF) and simulated intestinal fluid (SIF). Methods Multilayer polyelectrolyte AC microcapsules were fabricated using the layer-by-layer (LbL) self-assembly technique through electrostatic interactions. Results AC and ACAC microcapsules kept their integrity and mechanical stability in simulated gastric conditions. Bacterial cells remained inside microcapsules in SGF and dissolution of microcapsules was observed in SIF. To improve the bacterial survivability, L. rhamnosus was co-encapsulated in a double bilayer of AC hydrogels with calcium carbonate as an antacid agent. Conclusions The LbL self-assembly technology provides stable and target release for ACAC microcapsules. Therefore, the double bilayer polyelectrolyte microcapsules have a remarkable potential for successful application in the targeted and controlled delivery of different probiotics and drugs.
MeSH term(s)	Capsules ; Hexuronic Acids ; Polyelectrolytes ; Glucuronic Acid ; Lactobacillus rhamnosus ; Alginates ; Chitosan ; Probiotics
Chemical Substances	Capsules ; Hexuronic Acids ; Polyelectrolytes ; Glucuronic Acid (8A5D83Q4RW) ; Alginates ; Chitosan (9012-76-4)
Language	English
Publishing date	2022-09-24
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	423853-9
ISSN	1573-6776 ; 0141-5492
ISSN (online)	1573-6776
ISSN	0141-5492
DOI	10.1007/s10529-022-03289-0
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Article: Multi-Objective Optimization of Copper Bioleaching: Comparative Study of Pure and Co-Cultured Cultivation.

Rakhshani, Yasin / Rahpeyma, Sayyed Shahryar / Tabandeh, Fatemeh / Arabnezhad, Mahmood / Azimi, Ali / Raheb, Jamshid

Iranian journal of biotechnology

2023 Volume 21, Issue 2, Page(s) e3278

Abstract: Background: Bioleaching is a practical method to recover metals from low-grade mineral sulfides. The most frequent bacteria involved in the bioleaching of metals from ores are : Objectives: This study aimed to optimize the bioleaching condition of ... ...

Abstract	Background: Bioleaching is a practical method to recover metals from low-grade mineral sulfides. The most frequent bacteria involved in the bioleaching of metals from ores are Objectives: This study aimed to optimize the bioleaching condition of two indigenous iron- and sulfur-oxidizing bacteria from the Meydouk mine, Iran, and evaluate their function in a semi-pilot operation in pure and mixed cultures. Material and methods: After treatment with sulfuric acid, the bacterial DNA was extracted, and further 16S rRNA was sequenced to characterize the bacterial species. The cultivation condition of these bacteria was optimized using Design-expert (6.1.1 version) software. The copper recovery rate and the differentiation in the ORP rate in the percolation columns were also investigated. These strains were isolated from the Meydouk mine for the first time. Results: 16S rRNA analysis revealed that both bacteria belong to the Conclusions: Utilizing a mixture of both bacteria,
Language	English
Publishing date	2023-04-01
Publishing country	Iran
Document type	Journal Article
ZDB-ID	2223669-7
ISSN	2322-2921 ; 1728-3043
ISSN (online)	2322-2921
ISSN	1728-3043
DOI	10.30498/ijb.2023.328969.3278
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Article ; Online: Hyaluronic acid-graphene quantum dot nanocomposite: Potential target drug delivery and cancer cell imaging.

Vahedi, Nasrin / Tabandeh, Fatemeh / Mahmoudifard, Matin

Biotechnology and applied biochemistry

2021 Volume 69, Issue 3, Page(s) 1068–1079

Abstract: Nowadays, the use of nanoparticle-based drug delivery systems has received much more attention. In this regard, here, graphene quantum dots (GQD) were used as drug carriers as well as imaging agents for cancer cells. In order to optimize the dose of the ... ...

Abstract	Nowadays, the use of nanoparticle-based drug delivery systems has received much more attention. In this regard, here, graphene quantum dots (GQD) were used as drug carriers as well as imaging agents for cancer cells. In order to optimize the dose of the drug and reduce its side effects for healthy cells, hyaluronic acid was decorated on the surface of GQD to target cancer cells. The morphology and size of the synthesized nanoparticles alone and conjugated with hyaluronic acid were investigated using scanning electron microscopy (SEM) and transmission electron microscopy (TEM); TEM images revealed a particles size of ∼5.67 and ∼8.69 nm, respectively. In the presence of 1-ethyl-3-[3(dimethylamino)propyl]carbodiimide hydrochloride/N-hydroxysuccinimide (EDC/NHS), hyaluronic acid was bounded to dopamine hydrochloride and was prepared to react with GQD. After synthesis of graphene quantum dot-hyaluronic acid nanocomposite, curcumin (CUR) as a drug model was loaded on the synthesized nanocarriers, and its loading percentage was measured. The results showed that 98.02% of the drug was loaded on the nanocarriers. Also, the conjugation of each agent on the nanocarrier was approved by photoluminescence spectroscopy, Fourier transform infrared spectroscopy (FTIR), and UV-visible absorption techniques, and the results showed that the reactions were performed correctly. The effect of GQD, graphene quantum dot-hyaluronic acid, CUR, graphene quantum dot-hyaluronic acid-CUR on the viability of HeLa and L929 cells was evaluated by the MTT test. The results showed that the synthesized nanocarrier is completely biocompatible, and the drug nanocarriers reduce HeLa cell viability significantly due to the mediation of hyaluronic acid-CD44 for drug cell uptake. Simultaneously with drug delivery, the other goal of these nanocarriers is to image cancer cells by emitting fluorescent light. Fluorescent microscopy showed that these nanocarriers were adsorbed on HeLa cells, unlike L929 cells.
MeSH term(s)	Curcumin ; Drug Delivery Systems ; Graphite/chemistry ; Graphite/pharmacology ; HeLa Cells ; Humans ; Hyaluronic Acid/chemistry ; Nanocomposites/chemistry ; Neoplasms/drug therapy ; Quantum Dots/chemistry
Chemical Substances	Graphite (7782-42-5) ; Hyaluronic Acid (9004-61-9) ; Curcumin (IT942ZTH98)
Language	English
Publishing date	2021-05-10
Publishing country	United States
Document type	Journal Article
ZDB-ID	883433-7
ISSN	1470-8744 ; 0885-4513
ISSN (online)	1470-8744
ISSN	0885-4513
DOI	10.1002/bab.2178
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Article: Enhanced hyaluronic acid production in Streptococcus zooepidemicus by an optimized culture medium containing hyaluronidase inhibitor

Samadi, Mohaddeseh / Khodabandeh Shahraky, Mahvash / Tabandeh, Fatemeh / Aminzadeh, Saeed / Dina, Morshedi

Preparative biochemistry & biotechnology. 2022 Apr. 1, v. 52, no. 4

2022

Abstract: This study describes the hyaluronic acid (HA) production by S. zooepidemicus ATCC 43079, and the effect of the hyaluronidase enzyme on HA levels. The hyaluronidase production, glucose consumption, and lactate formation were recorded during fermentation. ... ...

Abstract	This study describes the hyaluronic acid (HA) production by S. zooepidemicus ATCC 43079, and the effect of the hyaluronidase enzyme on HA levels. The hyaluronidase production, glucose consumption, and lactate formation were recorded during fermentation. The HA production, and productivity at different amounts of glucose, yeast extract and pH were evaluated by response surface statistical approach in presence of 6-O-palmytoil-l-ascorbic acid as a chemical inhibitor for biocatalyst hyaluronidase. Under optimum conditions, HA production was increased two-fold from 190 ± 17 mg L⁻¹ in basal medium to 384.6 ± 7.5 mg L⁻¹ in the optimized medium containing enzyme inhibitor. Furthermore, the results indicated that the chemical inhibitor could suppress the biocatalyst activity and prevent the HA loss at the end of the exponential phase of S. zooepidemicus ATCC 43079.
Keywords	Streptococcus equi subsp. zooepidemicus ; biocatalysts ; biotechnology ; culture media ; fermentation ; glucose ; hyaluronic acid ; hyaluronoglucosaminidase ; lactic acid ; pH ; statistical analysis ; yeast extract
Language	English
Dates of publication	2022-0401
Size	p. 413-423.
Publishing place	Taylor & Francis
Document type	Article
ZDB-ID	1322522-4
ISSN	1532-2297 ; 1082-6068
ISSN (online)	1532-2297
ISSN	1082-6068
DOI	10.1080/10826068.2021.1955710
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Article ; Online: Effects of bioactive peptides derived from feather keratin on plasma cholesterol level, lipid oxidation of meat, and performance of broiler chicks

Alahyaribeik, Samira / Nazarpour, Madineh / Tabandeh, Fatemeh / Honarbakhsh, Shirin / Sharifi, Seyed davood

Trop Anim Health Prod. 2022 Oct., v. 54, no. 5 p.271-271

2022

Abstract: In this research, the effect of mixed feather bioactive peptides (MFBPs) added in water, on intestinal health, meat quality, and plasma cholesterol level of broiler chickens, was evaluated. A total of 80 day-old male broiler chicks (Ross 308) were ... ...

Abstract	In this research, the effect of mixed feather bioactive peptides (MFBPs) added in water, on intestinal health, meat quality, and plasma cholesterol level of broiler chickens, was evaluated. A total of 80 day-old male broiler chicks (Ross 308) were randomly divided into two treatments with four replication pens. The dietary treatments were the drinking water with no additives (control) and drinking water containing 50 mg/L of MFBPs. Live weight and feed intake were measured at the end of starter (1–10 days), grower (11–24 days), and finisher (25–36 days) periods by calculating the average daily gain and feed conversion ratio. The results indicate that body weight gain was greater (P < 0.05) in birds that received MFBPs in the final period. At 24 days of age, the villus height and muscle layer thickness in different parts of the intestine were higher in birds that received bioactive peptides but epithelial thickness was lower than that in control birds (P < 0.05). In addition, the administration of MFBPs decreased (P < 0.01) serum total cholesterol, triglyceride, and low-density lipoprotein in broilers. Supplementation with MFBPs significantly reduced (P < 0.01) the malondialdehyde (MDA) amount in the thigh muscle. In conclusion, using the MFBPs in the diet of broilers could improve meat quality, cholesterol concentration in serum, and gut health.
Keywords	average daily gain ; blood serum ; body weight changes ; cholesterol ; diet ; feed conversion ; feed intake ; intestines ; keratin ; lipid peroxidation ; low density lipoprotein ; males ; malondialdehyde ; meat ; meat quality ; muscles ; peptides ; triacylglycerols ; villi
Language	English
Dates of publication	2022-10
Size	p. 271.
Publishing place	Springer Netherlands
Document type	Article ; Online
ZDB-ID	603363-5
ISSN	1573-7438 ; 0049-4747
ISSN (online)	1573-7438
ISSN	0049-4747
DOI	10.1007/s11250-022-03244-1
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Article ; Online: Enhanced survival of Lacticaseibacillus rhamnosus in simulated gastrointestinal conditions using layer-by-layer encapsulation

Chehreara, Afsaneh / Tabandeh, Fatemeh / Otadi, Maryam / Alihosseini, Afshar / Partovinia, Ali

Biotechnol Lett. 2022 Nov., v. 44, no. 11 p.1277-1286

2022

Abstract: OBJECTIVE: The release behavior of Lacticaseibacillus rhamnosus from single bilayer microcapsules of alginate-chitosan (AC) and its double bilayer (ACAC) was investigated in simulated gastric fluid (SGF) and simulated intestinal fluid (SIF). Methods ... ...

Abstract	OBJECTIVE: The release behavior of Lacticaseibacillus rhamnosus from single bilayer microcapsules of alginate-chitosan (AC) and its double bilayer (ACAC) was investigated in simulated gastric fluid (SGF) and simulated intestinal fluid (SIF). Methods Multilayer polyelectrolyte AC microcapsules were fabricated using the layer-by-layer (LbL) self-assembly technique through electrostatic interactions. Results AC and ACAC microcapsules kept their integrity and mechanical stability in simulated gastric conditions. Bacterial cells remained inside microcapsules in SGF and dissolution of microcapsules was observed in SIF. To improve the bacterial survivability, L. rhamnosus was co-encapsulated in a double bilayer of AC hydrogels with calcium carbonate as an antacid agent. Conclusions The LbL self-assembly technology provides stable and target release for ACAC microcapsules. Therefore, the double bilayer polyelectrolyte microcapsules have a remarkable potential for successful application in the targeted and controlled delivery of different probiotics and drugs.
Keywords	antacids ; calcium carbonate ; electrolytes ; encapsulation ; gastric juice ; gastrointestinal system ; hydrogels ; intestinal secretions ; probiotics
Language	English
Dates of publication	2022-11
Size	p. 1277-1286.
Publishing place	Springer Netherlands
Document type	Article ; Online
ZDB-ID	423853-9
ISSN	1573-6776 ; 0141-5492
ISSN (online)	1573-6776
ISSN	0141-5492
DOI	10.1007/s10529-022-03289-0
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Article: Efficacy of hyaluronic acid, absorbable collagen sponge, and their combination in minimizing bisphosphonate-related osteonecrosis of the jaws (BRONJ) after dental extraction: a preliminary animal histomorphometric study.

Sarkarat, Farzin / Modarresi, Alireza / Riyahi, Arefeh / Mortazavi, Pejman / Tabandeh, Fatemeh / Rakhshan, Vahid

Maxillofacial plastic and reconstructive surgery

2022 Volume 44, Issue 1, Page(s) 8

Abstract: Introduction: There is no study on the effectiveness of hyaluronic acid (HA) placement either with or without absorbable collagen sponge (ACS) in reducing or preventing bisphosphonate-related osteonecrosis of the jaws (BRONJ). This preliminary animal ... ...

Abstract	Introduction: There is no study on the effectiveness of hyaluronic acid (HA) placement either with or without absorbable collagen sponge (ACS) in reducing or preventing bisphosphonate-related osteonecrosis of the jaws (BRONJ). This preliminary animal study examined the efficacy of this clinically important treatment. Methods: For simulating BRONJ, zoledronic acid was administered to 40 rats for 5 weeks. Two weeks later, a right first molar was extracted from each rat. The rats were randomized into four groups of socket treatments: control (empty extraction socket) or with sockets filled with ACS, HA, or HA+ACS (n=4×10). After 2 weeks, 5 rats in each group were sacrificed and subjected to histopathologic and histomorphometric evaluation. Eight weeks post-surgically, the rest of rats were euthanized and histologically examined. The Kruskal-Wallis test was used to compare the four treatments at each time point (α=0.05). Results: Six rats were lost overall. In the second week, vascularization was higher in ACS group (P<0.05); osteoclast activity was not different between groups (P>0.05); empty lacunae were the most and fewest in control and HA+ACS groups, respectively (P<0.05); eosinophil infiltration was maximum in HA group (P<0.05); lymphocyte counts were maximum and minimum in the HA+ACS and ACS groups, respectively (P<0.05); the highest and lowest neutrophil counts were seen in ACS and control groups, respectively (P<0.05); and the extent of live bone did not differ between groups (P>0.05). In the eighth week, vascularization was not different in groups (P>0.05); the highest and lowest osteoclast activities were seen in the control and HA+ACS groups, respectively (P<0.05); empty lacunae were the most and fewest in control and HA+ACS, respectively (P<0.05); maximum and minimum numbers of eosinophils were in control and HA+ACS groups, respectively (P<0.05); HA and control groups exhibited the highest and lowest lymphocyte counts, respectively (P<0.05); the lowest and highest neutrophil counts were observed in HA+ACs and control groups, respectively (P<0.05); and the highest and lowest extents of the live bone were observed in HA+ACS and control groups, respectively (P<0.05). Conclusions: Within the limitations of this preliminary animal study, HA and especially HA+ACS seem a proper method for preventing or treating BRONJ.
Language	English
Publishing date	2022-03-01
Publishing country	England
Document type	Journal Article
ISSN	2288-8101
ISSN	2288-8101
DOI	10.1186/s40902-022-00337-7
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Article ; Online: Effects of bioactive peptides derived from feather keratin on plasma cholesterol level, lipid oxidation of meat, and performance of broiler chicks.

Alahyaribeik, Samira / Nazarpour, Madineh / Tabandeh, Fatemeh / Honarbakhsh, Shirin / Sharifi, Seyed Davood

Tropical animal health and production

2022 Volume 54, Issue 5, Page(s) 271

Abstract	In this research, the effect of mixed feather bioactive peptides (MFBPs) added in water, on intestinal health, meat quality, and plasma cholesterol level of broiler chickens, was evaluated. A total of 80 day-old male broiler chicks (Ross 308) were randomly divided into two treatments with four replication pens. The dietary treatments were the drinking water with no additives (control) and drinking water containing 50 mg/L of MFBPs. Live weight and feed intake were measured at the end of starter (1-10 days), grower (11-24 days), and finisher (25-36 days) periods by calculating the average daily gain and feed conversion ratio. The results indicate that body weight gain was greater (P < 0.05) in birds that received MFBPs in the final period. At 24 days of age, the villus height and muscle layer thickness in different parts of the intestine were higher in birds that received bioactive peptides but epithelial thickness was lower than that in control birds (P < 0.05). In addition, the administration of MFBPs decreased (P < 0.01) serum total cholesterol, triglyceride, and low-density lipoprotein in broilers. Supplementation with MFBPs significantly reduced (P < 0.01) the malondialdehyde (MDA) amount in the thigh muscle. In conclusion, using the MFBPs in the diet of broilers could improve meat quality, cholesterol concentration in serum, and gut health.
MeSH term(s)	Animal Feed/analysis ; Animal Nutritional Physiological Phenomena ; Animals ; Chickens/physiology ; Cholesterol ; Diet/veterinary ; Dietary Supplements ; Drinking Water ; Feathers ; Keratins ; Male ; Meat/analysis ; Peptides
Chemical Substances	Drinking Water ; Peptides ; Keratins (68238-35-7) ; Cholesterol (97C5T2UQ7J)
Language	English
Publishing date	2022-08-30
Publishing country	United States
Document type	Journal Article ; Randomized Controlled Trial, Veterinary
ZDB-ID	603363-5
ISSN	1573-7438 ; 0049-4747
ISSN (online)	1573-7438
ISSN	0049-4747
DOI	10.1007/s11250-022-03244-1
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Article: Preparation, purification, and characterization of low-molecular-weight hyaluronic acid

Karami, Mohammad / Shahraky, Mahvash Khodabandeh / Ranjbar, Masume / Tabandeh, Fatemeh / Morshedi, Dina / Aminzade, Saeed

Biotechnology letters. 2021 Jan., v. 43, no. 1

2021

Abstract: OBJECTIVE: The use and commercial value of hyaluronic acid (HA) as an important element in the pharmaceutical, biomedical, and cosmetics industry is because of its purity. Four recombinant strains of Corynebacterium glutamicum containing different genes ... ...

Abstract	OBJECTIVE: The use and commercial value of hyaluronic acid (HA) as an important element in the pharmaceutical, biomedical, and cosmetics industry is because of its purity. Four recombinant strains of Corynebacterium glutamicum containing different genes were used to produce HA. RESULTS: The production parameters were measured and strain 183.2, with the highest amount of HA (2.15 mg/ml), was selected for further experiments. HA was precipitated by different ratios of ethanol-isopropanol at 4 °C and − 20 °C. Active charcoal (1%) was added to the solvent precipitation mixture at pH 5 and 10. Finally, to achieve more purity and separation, gel filtration chromatography was used. The best result was obtained using an ethanol-isopropanol ratio of 1:1 of at − 20 °C, followed by active charcoal treatment at the acidic pH, and three fractions of the chromatography with molecular weights of 27, 27–110, and < 27 KDa were more analyzed with electrophoresis and FTIR. CONCLUSIONS: The present study described a simple, economical, and reproducible method resulting in a high yield for low-MW HA from C. glutamicum.
Keywords	Corynebacterium glutamicum ; biotechnology ; charcoal ; cosmetics ; electrophoresis ; gel chromatography ; hyaluronic acid ; industry ; pH ; solvents
Language	English
Dates of publication	2021-01
Size	p. 133-142.
Publishing place	Springer Netherlands
Document type	Article
Note	NAL-AP-2-clean
ZDB-ID	423853-9
ISSN	1573-6776 ; 0141-5492
ISSN (online)	1573-6776
ISSN	0141-5492
DOI	10.1007/s10529-020-03035-4
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Article ; Online: Regenerative medicine as a novel strategy for AMD treatment: a review.

Tavakoli, Zahra / Yazdian, Fatemeh / Tabandeh, Fatemeh / Sheikhpour, Mojgan

Biomedical physics & engineering express

2019 Volume 6, Issue 1, Page(s) 12001

Abstract: Age-related macular degeneration (AMD) is known as a major cause of irreversible blindness in elderly adults. The segment of the retina responsible for central vision damages in the disease process. Degeneration of retinal pigmented epithelium (RPE) ... ...

Abstract	Age-related macular degeneration (AMD) is known as a major cause of irreversible blindness in elderly adults. The segment of the retina responsible for central vision damages in the disease process. Degeneration of retinal pigmented epithelium (RPE) cells, photoreceptors, and choriocapillaris associated with aging participate for visual loss. In 2010, AMD involved 6.6% of all blindness cases around the world. Some of the researches have evaluated the replacing of damaged RPE in AMD patients by using the cells from various sources. Today, the advancement of RPE differentiation or generation from stem cells has been gained, and currently, clinical trials are testing the efficiency and safety of replacing degenerated RPE with healthy RPE. However, the therapeutic success of RPE transplantation may be restricted unless the transplanted cells can be adhered, distributed and survive for long-term in the transplanted site without any infections. In recent years a variety of scaffold types were used as a carrier for RPE transplantation and AMD treatment. In this review, we have discussed types of scaffolds; natural or synthetic, solid or hydrogel and their results in RPE replacement. Eventually, our aim is highlighting the novel and best scaffold carriers that may have potentially promoting the efficacy of RPE transplantation.
MeSH term(s)	Aged ; Aged, 80 and over ; Female ; Humans ; Macular Degeneration/pathology ; Macular Degeneration/therapy ; Male ; Regenerative Medicine/methods ; Retina/pathology ; Retinal Pigment Epithelium/pathology ; Retinal Pigment Epithelium/transplantation ; Stem Cell Transplantation
Language	English
Publishing date	2019-11-13
Publishing country	England
Document type	Journal Article ; Review
ISSN	2057-1976
ISSN (online)	2057-1976
DOI	10.1088/2057-1976/ab269a
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