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  1. Article: Efficacy of Laser Therapy in Trigeminal Neuralgia: a Systematic Review.

    Haghighat, Sara / Rezazadeh, Fahimeh / Sedarat, Hossein / Tabesh, Amir / Tayebi Khorami, Elham / Aghasadeghi, Kiana

    Journal of dentistry (Shiraz, Iran)

    2024  Volume 25, Issue 1, Page(s) 17–25

    Abstract: Statement of the problem: Trigeminal neuralgia is the most common and disabling type of neuralgia in craniofacial region. Because of adverse effects of first and second lines of treatment, new modalities including laser therapy have been investigated ... ...

    Abstract Statement of the problem: Trigeminal neuralgia is the most common and disabling type of neuralgia in craniofacial region. Because of adverse effects of first and second lines of treatment, new modalities including laser therapy have been investigated for treatment of trigeminal neuralgia.
    Purpose: The aim of this study was to review the effect of laser in trigeminal neuralgia. PubMed, Scopus, Web of Science, Science Direct, and Embase databases from December 1983 to August 2020 were searched using keywords "trigeminal neuralgia" and "laser". Our inclusion criteria were interventional studies with a randomized clinical trial design, which used laser for treatment of trigeminal neuralgia.
    Materials and method: In this systematic review, a total of 269 records were identified through systematically searching aforementioned databases among which, 30 were from PubMed and 44 were from Web of Science. A total of 111 records were duplicated and were therefore removed.
    Results: Only 17 records were considered relevant after reading title and abstracts. After reading full texts of the articles, 13 met the eligibility criteria and were included in our review.
    Conclusion: This review revealed that low-level laser therapy reduces pain in trigeminal neuralgia specially diode lasers, although there are no standardized protocols for laser procedures.
    Language English
    Publishing date 2024-03-01
    Publishing country Iran
    Document type Journal Article ; Review
    ISSN 2345-6485
    ISSN 2345-6485
    DOI 10.30476/dentjods.2023.95758.1889
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Evaluation of the salivary level of glutathione reductase, catalase and free thiol in patients with oral lichen planus.

    Rezazadeh, Fahimeh / Mahdavi, Dorsa / Fassihi, Nima / Sedarat, Hossein / Tayebi Khorami, Elham / Tabesh, Amir

    BMC oral health

    2023  Volume 23, Issue 1, Page(s) 547

    Abstract: Objective: Oral lichen planus (OLP) is a usual chronic inflammatory disease of the oral mucosa with malignant capacity, whose pathogenesis is not yet well known. Free radicals and reactive oxygen species may have a vital role in the pathogenesis of oral ...

    Abstract Objective: Oral lichen planus (OLP) is a usual chronic inflammatory disease of the oral mucosa with malignant capacity, whose pathogenesis is not yet well known. Free radicals and reactive oxygen species may have a vital role in the pathogenesis of oral lichen planus. This study aimed to assess Glutathione reductase, catalase, and free thiol levels in the saliva of OLP patients and compare it with healthy people.
    Methods: In this cross-sectional study, 35 patients with OLP and 20 healthy people were involved. Five mL of whole, unstimulated saliva samples were collected in the morning, and the salivary levels of antioxidants were measured by ELISA technique. In this experiment, sex, age and OLP types were also evaluated.
    Results: There was a significant decrease in the patients' salivary level of Glutathione reductase (0.2043 mU/ml in patients and 0.3901 mU/ml in the control group) and catalase (0.1525 mU/ml in patients and 0.2700 mU/ml in the control group) (p = 0.001). But there were no differences between the two groups regarding free-thiol levels (0.0586 mU/ml in patients and 0.0569 mU/ml in the control group) (p = 0.7). However, there was no correlation between age and gender with the antioxidants' contents. There was a significant decrease in glutathione reductase and catalase in the erosive type than in the non-erosive type.
    Conclusions: In this study, we found that the salivary levels of Glutathione reductase and Catalase were lower in OLP patients than in the healthy group, which means these antioxidants were affected by OLP and also associated with the type of it. So salivary Glutathione reductase and Catalase levels may be used as biomarkers for OLP monitoring and treatment.
    MeSH term(s) Humans ; Catalase ; Glutathione Reductase ; Lichen Planus, Oral/pathology ; Cross-Sectional Studies ; Antioxidants ; Saliva ; Case-Control Studies
    Chemical Substances Catalase (EC 1.11.1.6) ; Glutathione Reductase (EC 1.8.1.7) ; Antioxidants
    Language English
    Publishing date 2023-08-09
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2091511-1
    ISSN 1472-6831 ; 1472-6831
    ISSN (online) 1472-6831
    ISSN 1472-6831
    DOI 10.1186/s12903-023-03242-1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Effect of periodontal surgery on the salivary Herpes simplex virus-1 levels-a pilot study.

    Rezazadeh, Fahimeh / Shojaei, Rana / Jamalidoust, Marzieh / Khosropanah, Hengameh / Tabesh, Amir / Tayebi Khorami, Elham

    Journal of oral biology and craniofacial research

    2023  Volume 13, Issue 4, Page(s) 482–485

    Abstract: Background and aim: Herpes simplex viruses (HSV) are one of the most important groups of human pathogenic viruses. The prominent characteristic of this virus is latency and the ability to reactivate. One of the possible factors for reactivation of this ... ...

    Abstract Background and aim: Herpes simplex viruses (HSV) are one of the most important groups of human pathogenic viruses. The prominent characteristic of this virus is latency and the ability to reactivate. One of the possible factors for reactivation of this virus is dental procedures. The aim of this study was to evaluate the salivary level of Herpes simplex viruses, before and after periodontal (crown lengthening) surgery and its relation with age and sex.
    Materials and methods: 30 HSV seropositive patients, who needed the crown lengthening surgery and accepted to cooperate in this research, were included as experimental group of this study. Unstimulated Saliva samples of the patients were collected in 1.5 ml micro-tubes, before and 24 h after the surgery, and were analyzed by Premix EX taq probe qpcr, using PCR real-time method.
    Results: No significant statistical differences were observed in the salivary level of HSV before and after crown lengthening procedure (p = 0.18). However, the level of HSV in saliva after surgery was significantly higher than its level before surgery in women as compared to men (p = 0.003). The differences in virus level did not have any significant relationship with patients' age (p = 0.9).
    Conclusion: It seems that periodontal (crown lengthening) surgery does not affect the level of HSV in saliva yet, but it could be one of the stimulators of increased HSV level after surgery in women as compared to men; but age does not play an important role in changes of level of virus before and after the surgery.
    Language English
    Publishing date 2023-05-31
    Publishing country Netherlands
    Document type Journal Article
    ISSN 2212-4268
    ISSN 2212-4268
    DOI 10.1016/j.jobcr.2023.05.005
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Effect of Non-Ablative Non-Thermal CO

    Rezazadeh, Fahimeh / Borhani-Haghighi, Afshin / Mosallanejad, Fatemeh / Showraki, Najmeh / Tabesh, Amir / Khorami, Elham Tayebi

    Photobiomodulation, photomedicine, and laser surgery

    2023  Volume 41, Issue 6, Page(s) 272–276

    Abstract: Background: ...

    Abstract Background:
    MeSH term(s) Humans ; Trigeminal Neuralgia/radiotherapy ; Trigeminal Neuralgia/surgery ; Pilot Projects ; Carbon Dioxide ; Treatment Outcome ; Pain
    Chemical Substances Carbon Dioxide (142M471B3J)
    Language English
    Publishing date 2023-06-19
    Publishing country United States
    Document type Randomized Controlled Trial ; Journal Article
    ISSN 2578-5478
    ISSN (online) 2578-5478
    DOI 10.1089/photob.2023.0023
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Evaluation of recurrence, mortality and treatment complications of oral squamous cell carcinoma in public health centers in Shiraz during 2010 to 2020.

    Rezazadeh, Fahimeh / Andisheh-Tadbir, Azadeh / Malek Mansouri, Zahra / Khademi, Bijan / Bayat, Pourya / Sedarat, Hossein / Tabesh, Amir / Tayebi Khorami, Elham

    BMC oral health

    2023  Volume 23, Issue 1, Page(s) 341

    Abstract: Introduction: Oral Squamous cell Carcinoma (OSCC) is the most common oral cancer and is treated with surgery, radiotherapy and chemotherapy. Various complications of treatment include xerostomia, mucositis, and trismus, which affect patients' quality of ...

    Abstract Introduction: Oral Squamous cell Carcinoma (OSCC) is the most common oral cancer and is treated with surgery, radiotherapy and chemotherapy. Various complications of treatment include xerostomia, mucositis, and trismus, which affect patients' quality of life. The aim of this study is to evaluate the mortality, recurrence rate and prevalence of oral complications in treated patients.
    Method and materials: This cross-sectional study reviewed 326 cases of patients with OSCC who were referred to public health centers in Shiraz (Khalili Hospital and Dental School) from 2010 to 2020. All patients were contacted, and the survivors were called and examined by an oral physician. A medical record was created for them, including demographic information, location of the lesion, type of treatment, history of recurrence, metastasis and oral complications.
    Results: 53.5% of patients were male and 46.5% were female. The mean age of patients was 58.68 years. Mortality and recurrence rate was respectively 49.8% and 17.8%. The most common location of the lesion was tongue (64%). Surgery was done for all patients. 97.4% of patients complained of xerostomia, 46.2% of mucositis and 44.3% of trismus.
    Conclusion: The most common complications of treatment are xerostomia, mucositis, and trismus, respectively. Frequent and regular follow-ups and supportive therapies reduce these complications and improve patients' quality of life.
    MeSH term(s) Humans ; Male ; Female ; Middle Aged ; Mouth Neoplasms/surgery ; Carcinoma, Squamous Cell/therapy ; Carcinoma, Squamous Cell/pathology ; Squamous Cell Carcinoma of Head and Neck ; Mucositis ; Trismus/etiology ; Trismus/therapy ; Cross-Sectional Studies ; Quality of Life ; Public Health ; Xerostomia/complications ; Head and Neck Neoplasms
    Language English
    Publishing date 2023-05-30
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2091511-1
    ISSN 1472-6831 ; 1472-6831
    ISSN (online) 1472-6831
    ISSN 1472-6831
    DOI 10.1186/s12903-023-03071-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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