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  1. Article ; Online: Ableism in the intensive care unit.

    Taccone, Fabio S

    Intensive care medicine

    2023  Volume 49, Issue 7, Page(s) 898–899

    MeSH term(s) Humans ; Intensive Care Units ; Social Discrimination
    Language English
    Publishing date 2023-04-28
    Publishing country United States
    Document type Journal Article
    ZDB-ID 80387-x
    ISSN 1432-1238 ; 0340-0964 ; 0342-4642 ; 0935-1701
    ISSN (online) 1432-1238
    ISSN 0340-0964 ; 0342-4642 ; 0935-1701
    DOI 10.1007/s00134-023-07084-x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 1089: Show issues Location:
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  2. Article ; Online: Magic mirror on the wall, which is the best meta-analysis one of all?

    Taccone, Fabio Silvio

    Critical care (London, England)

    2023  Volume 27, Issue 1, Page(s) 280

    Language English
    Publishing date 2023-07-11
    Publishing country England
    Document type Letter ; Comment
    ZDB-ID 2041406-7
    ISSN 1466-609X ; 1364-8535
    ISSN (online) 1466-609X
    ISSN 1364-8535
    DOI 10.1186/s13054-023-04564-w
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    Zs.A 5517: Show issues Location:
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  3. Article ; Online: Temperature management after cardiac arrest: what is next after the TTM-2 and BOX trials?

    Taccone, Fabio Silvio / Annoni, Filippo

    European heart journal. Acute cardiovascular care

    2023  Volume 12, Issue 8, Page(s) 504–506

    MeSH term(s) Humans ; Temperature ; Heart Arrest/therapy ; Body Temperature ; Hypothermia, Induced ; Out-of-Hospital Cardiac Arrest/therapy ; Cardiopulmonary Resuscitation
    Language English
    Publishing date 2023-07-25
    Publishing country England
    Document type Journal Article
    ZDB-ID 2663340-1
    ISSN 2048-8734 ; 2048-8726
    ISSN (online) 2048-8734
    ISSN 2048-8726
    DOI 10.1093/ehjacc/zuad088
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  4. Article ; Online: Disrupting the "Animal Farm" of scientific research and publishing: AI as an impartial sidekick.

    Salvagno, Michele / Taccone, Fabio Silvio

    Critical care (London, England)

    2023  Volume 27, Issue 1, Page(s) 365

    MeSH term(s) Animals ; Farms
    Language English
    Publishing date 2023-09-22
    Publishing country England
    Document type Letter
    ZDB-ID 2041406-7
    ISSN 1466-609X ; 1364-8535
    ISSN (online) 1466-609X
    ISSN 1364-8535
    DOI 10.1186/s13054-023-04647-8
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    Zs.A 5517: Show issues Location:
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  5. Article ; Online: Artificial intelligence is the new chief editor of Critical Care (maybe?).

    Salvagno, Michele / Taccone, Fabio Silvio

    Critical care (London, England)

    2023  Volume 27, Issue 1, Page(s) 270

    MeSH term(s) Humans ; Artificial Intelligence ; Critical Care
    Language English
    Publishing date 2023-07-06
    Publishing country England
    Document type Letter
    ZDB-ID 2041406-7
    ISSN 1466-609X ; 1364-8535
    ISSN (online) 1466-609X
    ISSN 1364-8535
    DOI 10.1186/s13054-023-04455-0
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  6. Article ; Online: Fever management in acute brain injury.

    Bogossian, Elisa Gouvea / Taccone, Fabio Silvio

    Current opinion in critical care

    2022  Volume 28, Issue 2, Page(s) 130–137

    Abstract: Purpose of review: Fever is common after acute brain injury and is associated with poor prognosis in this setting.: Recent findings: Achieving normothermia is feasible in patients with ischemic or hemorrhagic stroke, subarachnoid hemorrhage and ... ...

    Abstract Purpose of review: Fever is common after acute brain injury and is associated with poor prognosis in this setting.
    Recent findings: Achieving normothermia is feasible in patients with ischemic or hemorrhagic stroke, subarachnoid hemorrhage and traumatic brain injury. Pharmacological strategies (i.e. paracetamol or nonsteroidal anti-inflammatory drugs) are frequently ineffective and physical (i.e. cooling devices) therapies are often required. There are no good quality data supporting any benefit from therapeutic strategies aiming at normothermia in all brain injured patients when compared with standard of care, where mild-to-moderate fever is tolerated. However, recent guidelines recommended fever control in this setting.
    Summary: As fever is considered a clinically relevant secondary brain damage, we have provided an individualized therapeutic approach to treat it in brain injured patients, which deserved further validation in the clinical setting.
    MeSH term(s) Brain ; Brain Injuries/complications ; Brain Injuries/therapy ; Critical Care ; Fever/complications ; Fever/therapy ; Humans ; Subarachnoid Hemorrhage/complications ; Subarachnoid Hemorrhage/therapy
    Language English
    Publishing date 2022-01-14
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Review
    ZDB-ID 1235629-3
    ISSN 1531-7072 ; 1070-5295
    ISSN (online) 1531-7072
    ISSN 1070-5295
    DOI 10.1097/MCC.0000000000000918
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Incoherence between systemic and skin tissue response to transfusion in volume-resuscitated patients withoutacute bleeding.

    Cavalcante Dos Santos, Elaine / Creteur, Jacques / Taccone, Fabio Silvio

    Clinical hemorheology and microcirculation

    2024  

    Abstract: Alterations in skin blood flow (SBF) may help to detect occult hypoperfusion in critically ill patients after fluid resuscitation. In this study, SBF is globally unaltered by red blood cell transfusion (RBCT) in non-bleeding critically ill patients after ...

    Abstract Alterations in skin blood flow (SBF) may help to detect occult hypoperfusion in critically ill patients after fluid resuscitation. In this study, SBF is globally unaltered by red blood cell transfusion (RBCT) in non-bleeding critically ill patients after initial resuscitation; however, 37.5% of patients showed a significant increase in SBF. No correlation between relative changes in SBF and systemic variables after RBCT was observed.
    Language English
    Publishing date 2024-03-29
    Publishing country Netherlands
    Document type Letter
    ZDB-ID 1381750-4
    ISSN 1875-8622 ; 1386-0291
    ISSN (online) 1875-8622
    ISSN 1386-0291
    DOI 10.3233/CH-232091
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    Zs.A 1623: Show issues Location:
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  8. Article ; Online: "NeuroVanguard": a contemporary strategy in neuromonitoring for severe adult brain injury patients.

    Rodriguez, Edith Elianna / Zaccarelli, Mario / Sterchele, Elda Diletta / Taccone, Fabio Silvio

    Critical care (London, England)

    2024  Volume 28, Issue 1, Page(s) 104

    Abstract: Severe acute brain injuries, stemming from trauma, ischemia or hemorrhage, remain a significant global healthcare concern due to their association with high morbidity and mortality rates. Accurate assessment of secondary brain injuries severity is ... ...

    Abstract Severe acute brain injuries, stemming from trauma, ischemia or hemorrhage, remain a significant global healthcare concern due to their association with high morbidity and mortality rates. Accurate assessment of secondary brain injuries severity is pivotal for tailor adequate therapies in such patients. Together with neurological examination and brain imaging, monitoring of systemic secondary brain injuries is relatively straightforward and should be implemented in all patients, according to local resources. Cerebral secondary injuries involve factors like brain compliance loss, tissue hypoxia, seizures, metabolic disturbances and neuroinflammation. In this viewpoint, we have considered the combination of specific noninvasive and invasive monitoring tools to better understand the mechanisms behind the occurrence of these events and enhance treatment customization, such as intracranial pressure monitoring, brain oxygenation assessment and metabolic monitoring. These tools enable precise intervention, contributing to improved care quality for severe brain injury patients. The future entails more sophisticated technologies, necessitating knowledge, interdisciplinary collaboration and resource allocation, with a focus on patient-centered care and rigorous validation through clinical trials.
    MeSH term(s) Adult ; Humans ; Critical Care/methods ; Intracranial Pressure ; Brain Injuries/therapy ; Brain Injuries/complications ; Brain ; Brain Injuries, Traumatic ; Monitoring, Physiologic/methods
    Language English
    Publishing date 2024-04-01
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2041406-7
    ISSN 1466-609X ; 1364-8535
    ISSN (online) 1466-609X
    ISSN 1364-8535
    DOI 10.1186/s13054-024-04893-4
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  9. Article: How to Use Nebulized Antibiotics in Severe Respiratory Infections.

    Gorham, Julie / Taccone, Fabio S / Hites, Maya

    Antibiotics (Basel, Switzerland)

    2023  Volume 12, Issue 2

    Abstract: Difficult-to-treat pulmonary infections caused by multidrug-resistant (MDR) pathogens are of great concern because their incidence continues to increase worldwide and they are associated with high morbidity and mortality. Nebulized antibiotics are ... ...

    Abstract Difficult-to-treat pulmonary infections caused by multidrug-resistant (MDR) pathogens are of great concern because their incidence continues to increase worldwide and they are associated with high morbidity and mortality. Nebulized antibiotics are increasingly being used in this context. The advantages of the administration of a nebulized antibiotic in respiratory tract infections due to MDR include the potential to deliver higher drug concentrations to the site of infection, thus minimizing the systemic adverse effects observed with the use of parenteral or oral antibiotic agents. However, there is an inconsistency between the large amount of experimental evidence supporting the administration of nebulized antibiotics and the paucity of clinical studies confirming the efficacy and safety of these drugs. In this narrative review, we describe the current evidence on the use of nebulized antibiotics for the treatment of severe respiratory infections.
    Language English
    Publishing date 2023-01-28
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2681345-2
    ISSN 2079-6382
    ISSN 2079-6382
    DOI 10.3390/antibiotics12020267
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  10. Article ; Online: Multimodal neuromonitoring in traumatic brain injury patients: the search for the Holy Graal.

    Taccone, Fabio Silvio / Sterchele, Elda Diletta / Piagnerelli, Michael

    Critical care (London, England)

    2023  Volume 27, Issue 1, Page(s) 396

    MeSH term(s) Humans ; Oxygen ; Brain Injuries, Traumatic/therapy ; Brain
    Chemical Substances Oxygen (S88TT14065)
    Language English
    Publishing date 2023-10-16
    Publishing country England
    Document type Letter ; Comment
    ZDB-ID 2041406-7
    ISSN 1466-609X ; 1364-8535
    ISSN (online) 1466-609X
    ISSN 1364-8535
    DOI 10.1186/s13054-023-04679-0
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