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Article ; Online: Methylmercury Decreases AMPA Receptor Subunit GluA2 Levels in Cultured Rat Cortical Neurons.

Ishida, Keishi / Takeda, Kazuki / Takehara, Yuki / Takabayashi, Tomoki / Miyara, Masatsugu / Sanoh, Seigo / Kawai, Hidehiko / Ohta, Shigeru / Kotake, Yaichiro

Biological & pharmaceutical bulletin

2023  Volume 46, Issue 2, Page(s) 292–300

Abstract: Methylmercury (MeHg) is a well-known environmental pollutant that has harmful effects on the central nervous systems of humans and animals. The molecular mechanisms of MeHg-induced neurotoxicity at low concentrations are not fully understood. Here, we ... ...

Abstract Methylmercury (MeHg) is a well-known environmental pollutant that has harmful effects on the central nervous systems of humans and animals. The molecular mechanisms of MeHg-induced neurotoxicity at low concentrations are not fully understood. Here, we investigated the effects of low-concentration MeHg on the cell viability, Ca
MeSH term(s) Animals ; Rats ; Calcium/metabolism ; Cells, Cultured ; Glutamic Acid/metabolism ; Homeostasis ; Methylmercury Compounds/metabolism ; Neurons ; Receptors, AMPA/metabolism
Chemical Substances Calcium (SY7Q814VUP) ; Glutamic Acid (3KX376GY7L) ; Methylmercury Compounds ; Receptors, AMPA
Language English
Publishing date 2023-01-29
Publishing country Japan
Document type Journal Article
ZDB-ID 1150271-x
ISSN 1347-5215 ; 0918-6158
ISSN (online) 1347-5215
ISSN 0918-6158
DOI 10.1248/bpb.b22-00744
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