LIVIVO - Search results -

Search results

Result 1 - 10 of total 12

Search options

Article ; Online: Assessment of the in vitro acaricidal activity of Bravecto

Takano, Kotaro / Carver, Scott / Vermaak, Yolandi / Fischer, Katja / Harvey, Robert J / Mounsey, Kate E

2024 Volume 17, Issue 1, Page(s) 194

Abstract: Background: Sarcoptic mange is a serious animal welfare concern in bare-nosed wombats (Vombatus ursinus). Fluralaner (Bravecto: Methods: Sarcoptes scabiei were sourced from experimentally infested pigs. In vitro assays were performed to determine the ...

Abstract	Background: Sarcoptic mange is a serious animal welfare concern in bare-nosed wombats (Vombatus ursinus). Fluralaner (Bravecto Methods: Sarcoptes scabiei were sourced from experimentally infested pigs. In vitro assays were performed to determine the lethal concentration (LC Results: All compounds were highly effective at killing mites in vitro. The LC Conclusions: These results confirm the acaricidal properties of Bravecto, demonstrate acaricidal properties of Orange Power and support the potential suitability of Orange Power and its active constituents as a diluent for Bravecto. As well as killing mites via direct exposure, Orange Power could potentially enhance the topical delivery of Bravecto to wombats by increasing drug penetration in hyperkeratotic crusts. Further research evaluating the physiochemical properties and modes of action of Orange Power and its constituents as a formulation vehicle would be of value.
MeSH term(s)	Animals ; Sarcoptes scabiei/drug effects ; Acaricides/pharmacology ; Isoxazoles/pharmacology ; Scabies/drug therapy ; Scabies/parasitology ; Plant Oils/pharmacology ; Plant Oils/chemistry ; Acyclic Monoterpenes/pharmacology ; Swine ; Limonene/pharmacology ; Limonene/chemistry ; Terpenes/pharmacology ; Terpenes/chemistry ; Cyclohexenes/pharmacology ; Cyclohexenes/chemistry ; Lethal Dose 50
Chemical Substances	Acaricides ; A1443 compound ; Isoxazoles ; Plant Oils ; orange oil (AKN3KSD11B) ; citral (T7EU0O9VPP) ; Acyclic Monoterpenes ; Limonene (9MC3I34447) ; Terpenes ; Cyclohexenes
Language	English
Publishing date	2024-04-25
Publishing country	England
Document type	Journal Article
ZDB-ID	2409480-8
ISSN	1756-3305 ; 1756-3305
ISSN (online)	1756-3305
ISSN	1756-3305
DOI	10.1186/s13071-024-06275-9
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

Article: Establishing a ready biodegradability test system using OxiTop® to evaluate chemical fate in a realistic environment.

Takekoshi, Saki / Takano, Kotaro / Matoba, Yoshihide / Mukumoto, Makiko / Tachibana, Akira

Journal of pesticide science

2022 Volume 47, Issue 1, Page(s) 35–42

Abstract: The purpose of this study is to propose the use of OxiTop® for measuring biochemical oxygen demand (BOD) under the Japanese Chemical Substances Control Law in order to properly evaluate chemical fate in a real environment. In our previous study, the ... ...

Abstract	The purpose of this study is to propose the use of OxiTop® for measuring biochemical oxygen demand (BOD) under the Japanese Chemical Substances Control Law in order to properly evaluate chemical fate in a real environment. In our previous study, the biodegradation of test chemicals was accelerated by both adsorbing the chemical to silica gel with chloroform and increasing the medium volume from 300 to 3900 mL in the OECD 301F test using a coulometer. However, the biodegradability of these chemicals could not be evaluated based on BOD due to chloroform residue in the silica gel, or the medium volume could not be increased further due to the oven size of the coulometer. In this study, we established an evaluation system using OxiTop® based on BOD by increasing the medium volume to 9000 mL. Based on triplicate testing, increasing the medium volume accelerated biodegradation and decreased variation in BOD.
Language	English
Publishing date	2022-04-05
Publishing country	Japan
Document type	Journal Article
ZDB-ID	437867-2
ISSN	1348-589X ; 2187-0365 ; 0916-9962 ; 0385-1559
ISSN	1348-589X ; 2187-0365 ; 0916-9962 ; 0385-1559
DOI	10.1584/jpestics.D21-046
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Bonn / Germany

Z 3160: Show issues

Order via subito

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Pharmacokinetic and pharmacodynamic considerations for treating sarcoptic mange with cross-relevance to Australian wildlife.

Takano, Kotaro / de Hayr, Lachlan / Carver, Scott / Harvey, Robert J / Mounsey, Kate E

International journal for parasitology. Drugs and drug resistance

2023 Volume 21, Page(s) 97–113

Abstract: Sarcoptes scabiei is the microscopic burrowing mite responsible for sarcoptic mange, which is reported in approximately 150 mammalian species. In Australia, sarcoptic mange affects a number of native and introduced wildlife species, is particularly ... ...

Abstract	Sarcoptes scabiei is the microscopic burrowing mite responsible for sarcoptic mange, which is reported in approximately 150 mammalian species. In Australia, sarcoptic mange affects a number of native and introduced wildlife species, is particularly severe in bare-nosed wombats (Vombatus ursinus) and an emerging issue in koala and quenda. There are a variety of acaricides available for the treatment of sarcoptic mange which are generally effective in eliminating mites from humans and animals in captivity. In wild populations, effective treatment is challenging, and concerns exist regarding safety, efficacy and the potential emergence of acaricide resistance. There are risks where acaricides are used intensively or inadequately, which could adversely affect treatment success rates as well as animal welfare. While reviews on epidemiology, treatment strategies, and pathogenesis of sarcoptic mange in wildlife are available, there is currently no review evaluating the use of specific acaricides in the context of their pharmacokinetic and pharmacodynamic properties, and subsequent likelihood of emerging drug resistance, particularly for Australian wildlife. This review critically evaluates acaricides that have been utilised to treat sarcoptic mange in wildlife, including dosage forms and routes, pharmacokinetics, mode of action and efficacy. We also highlight the reports of resistance of S. scabiei to acaricides, including clinical and in vitro observations.
MeSH term(s)	Animals ; Humans ; Scabies/drug therapy ; Scabies/veterinary ; Scabies/epidemiology ; Animals, Wild ; Acaricides/therapeutic use ; Acaricides/pharmacology ; Australia/epidemiology ; Sarcoptes scabiei ; Mammals
Chemical Substances	Acaricides
Language	English
Publishing date	2023-03-05
Publishing country	Netherlands
Document type	Journal Article ; Review ; Research Support, Non-U.S. Gov't
ZDB-ID	2751132-7
ISSN	2211-3207 ; 2211-3207
ISSN (online)	2211-3207
ISSN	2211-3207
DOI	10.1016/j.ijpddr.2023.02.004
Database	MEDical Literature Analysis and Retrieval System OnLINE

Full text online

Accessible to users with ZB MED library card

Order via subito

Details ▾
- Full text online
- Order with fees

Article: Metagenomic analysis of ready biodegradability tests to ascertain the relationship between microbiota and the biodegradability of test chemicals.

Takano, Yoshinari / Takekoshi, Saki / Takano, Kotaro / Matoba, Yoshihide / Mukumoto, Makiko / Shirai, Osamu

Journal of pesticide science

2023 Volume 48, Issue 2, Page(s) 35–46

Abstract: Ready biodegradability tests conducted in accordance with the Organisation for Economic Co-operation and Development guidelines (test 301C or test 301F) are performed using activated sludge (AS) prepared by the Chemicals Evaluation and Research Institute ...

Abstract	Ready biodegradability tests conducted in accordance with the Organisation for Economic Co-operation and Development guidelines (test 301C or test 301F) are performed using activated sludge (AS) prepared by the Chemicals Evaluation and Research Institute (AS-CERI) or that taken from a sewage treatment plant (AS-STP). It had been reported that AS-CERI had lower activity than AS-STP in biodegrading test chemicals, and that biodegradation was accelerated by increasing the volume of the test medium. However, these phenomena have not been clarified from the perspective of the microbiota. In this study, using metagenomic analysis, we first showed that the microbiota of AS-CERI was biased in its distribution of phyla, less diverse, and had greater lot-to-lot variability than that of AS-STP. Second, after cultivation for a long period of time, the microbiota of AS-STP and AS-CERI became more similar to each other in terms of community structure. Third, determining degraders of test substances when each substance was actively biodegraded was found to be an effective approach. Finally, we clarified experimentally that a large volume of test medium increased the number of species that could degrade test substances in the condition where the initial concentrations of each substance and AS-STP were kept constant.
Language	English
Publishing date	2023-06-08
Publishing country	Japan
Document type	Journal Article
ZDB-ID	437867-2
ISSN	1348-589X ; 2187-0365 ; 0916-9962 ; 0385-1559
ISSN	1348-589X ; 2187-0365 ; 0916-9962 ; 0385-1559
DOI	10.1584/jpestics.D22-067
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Bonn / Germany

Z 3160: Show issues

Order via subito

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Details ▾
- See ZB MED holdings
- Order with fees

Article: Investigation of OECD 301F ready biodegradability test to evaluate chemical fate in a realistic environment.

Takekoshi, Saki / Takano, Kotaro / Matoba, Yoshihide / Sato, Masayuki / Tachibana, Akira

Journal of pesticide science

2021 Volume 46, Issue 2, Page(s) 143–151

Abstract: The OECD 301F ready biodegradability test has been approved for use under the Japanese Chemical Substances Control Law since 2018. This test uses activated sludge obtained from a sewage treatment plant instead of the standard activated sludge used for ... ...

Abstract	The OECD 301F ready biodegradability test has been approved for use under the Japanese Chemical Substances Control Law since 2018. This test uses activated sludge obtained from a sewage treatment plant instead of the standard activated sludge used for the 301C test. In addition, the test is allowed to add an inert support or emulsifying agent, and/or to change the volume of the test medium. In this study, we first confirmed that the standard sludge had lower biodegradation activities than the sludge taken from a sewage treatment plant. Second, we showed that biodegradation percentages were increased by adding suitable amounts of silica gel or Tween 80. Third, we found that the biodegradations were accelerated by only increasing the medium volume under the conditions that concentrations of chemical, silica gel, and sludge were held constant. These findings are expected to contribute to the appropriate evaluation of chemical fate in a realistic environment.
Language	English
Publishing date	2021-04-23
Publishing country	Japan
Document type	Journal Article
ZDB-ID	437867-2
ISSN	1348-589X ; 2187-0365 ; 0916-9962 ; 0385-1559
ISSN	1348-589X ; 2187-0365 ; 0916-9962 ; 0385-1559
DOI	10.1584/jpestics.D20-050
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Bonn / Germany

Z 3160: Show issues

Order via subito

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Drug dose and animal welfare: important considerations in the treatment of wildlife.

Mounsey, Kate / Harvey, Robert J / Wilkinson, Victoria / Takano, Kotaro / Old, Julie / Stannard, Hayley / Wicker, Leanne / Phalen, David / Carver, Scott

Parasitology research

2022 Volume 121, Issue 3, Page(s) 1065–1071

Abstract: A recent publication in Parasitology Research by (Old et al. Parasitol Res 120:1077-1090, 2021) raises the topical and often controversial issue of the treatment of wildlife by personnel with little or no formal scientific training (e.g. wildlife carers). ...

Abstract	A recent publication in Parasitology Research by (Old et al. Parasitol Res 120:1077-1090, 2021) raises the topical and often controversial issue of the treatment of wildlife by personnel with little or no formal scientific training (e.g. wildlife carers). In a valuable contribution to the subject, Old and colleagues document a wide range of topical (pour-on) application doses and frequencies of moxidectin (Cydectin®) administered in situ to bare-nosed wombats (Vombatus ursinus) by members of the wildlife carer/treater community in southeast Australia to treat sarcoptic mange disease. This treatment occurred under minor use permits issued by the Australian Pesticides and Veterinary Management Authority (APVMA). These permits do not require veterinary supervision, although carers are registered and are expected to comply with the guidelines of this permit.The prevalence and severity of sarcoptic mange in wildlife is influenced by a variety of factors including mite biology, environmental conditions, population density, animal behaviour and immune susceptibility (Browne et al. Bioscience, 2021). In bare-nosed wombats, combinations of these elements play a substantial role in making the treatment of an already difficult disease more complex. (Moroni et al. Parasit Vectors 13:471, 2020) comment that any pharmacological treatment of free-ranging wildlife must consider these factors when assessing their feasibility and implications, especially in the context of emerging drug resistance and potential long-term ecological impacts. As individuals with significant interest in sarcoptic mange and representing a range of professional research and veterinary expertise, we see value in providing expert commentary on this issue.
MeSH term(s)	Animal Welfare ; Animals ; Animals, Wild/parasitology ; Australia/epidemiology ; Humans ; Pharmaceutical Preparations ; Sarcoptes scabiei ; Scabies/veterinary
Chemical Substances	Pharmaceutical Preparations
Language	English
Publishing date	2022-02-11
Publishing country	Germany
Document type	Letter
ZDB-ID	284966-5
ISSN	1432-1955 ; 0932-0113 ; 0044-3255
ISSN (online)	1432-1955
ISSN	0932-0113 ; 0044-3255
DOI	10.1007/s00436-022-07460-4
Database	MEDical Literature Analysis and Retrieval System OnLINE

Full text online

Accessible to users with ZB MED library card

In stock of ZB MED Cologne/Königswinter

Uh II Zs.124: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾

Article ; Online: Correction to: Drug dose and animal welfare: important considerations in the treatment of wildlife.

Mounsey, Kate / Harvey, Robert J / Wilkinson, Victoria / Takano, Kotaro / Old, Julie / Stannard, Hayley / Wicker, Leanne / Phalen, David / Carver, Scott

Parasitology research

2022 Volume 121, Issue 5, Page(s) 1551

Language	English
Publishing date	2022-03-01
Publishing country	Germany
Document type	Published Erratum
ZDB-ID	284966-5
ISSN	1432-1955 ; 0932-0113 ; 0044-3255
ISSN (online)	1432-1955
ISSN	0932-0113 ; 0044-3255
DOI	10.1007/s00436-022-07472-0
Database	MEDical Literature Analysis and Retrieval System OnLINE

Full text online

Accessible to users with ZB MED library card

In stock of ZB MED Cologne/Königswinter

Uh II Zs.124: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾

Article: Drug dose and animal welfare: important considerations in the treatment of wildlife

Mounsey, Kate / Harvey, Robert J. / Wilkinson, Victoria / Takano, Kotaro / Old, Julie / Stannard, Hayley / Wicker, Leanne / Phalen, David / Carver, Scott

Parasitology research. 2022 Mar., v. 121, no. 3

2022

Abstract: A recent article published in Parasitology Research describes the use of high-dose moxidectin (Cydectin®) by wildlife carers for the treatment of sarcoptic mange in bare-nose wombats (Vombatus ursinus). We provide additional perspectives on this topic, ... ...

Abstract	A recent article published in Parasitology Research describes the use of high-dose moxidectin (Cydectin®) by wildlife carers for the treatment of sarcoptic mange in bare-nose wombats (Vombatus ursinus). We provide additional perspectives on this topic, including consideration of the pharmacokinetics, mode of action and efficacy of moxidectin. The volumes of moxidectin applied by some carers exceeded the manufacturer recommended dose by up to 100-fold, although there appeared to be no association between dose and clinical efficacy. The safety of these extremely high doses has not been scientifically evaluated and we raise concerns regarding the potential for severe adverse events that may be undetected in free-living animals. The inadvertent spillage of large volumes of pour-on acaricides may also have ecotoxic impacts. Reports of treatment failure prompting the perceived need for higher doses are also concerning. The causal factors behind treatment failures should be investigated as a matter of priority, as it is possible that moxidectin resistance is emerging in Sarcoptes scabiei mites infesting wombats. We welcome the insights of individuals actively engaged in the treatment of this debilitating disease of wombats and encourage further discourse, reflecting both the lived experience and evidence-based practice.
Keywords	Sarcoptes scabiei ; Vombatus ursinus ; animal welfare ; evidence-based practice ; mechanism of action ; moxidectin ; parasitology ; pharmacokinetics ; research ; scabies ; wildlife
Language	English
Dates of publication	2022-03
Size	p. 1065-1071.
Publishing place	Springer Berlin Heidelberg
Document type	Article
Note	Letter
ZDB-ID	284966-5
ISSN	1432-1955 ; 0932-0113 ; 0044-3255
ISSN (online)	1432-1955
ISSN	0932-0113 ; 0044-3255
DOI	10.1007/s00436-022-07460-4
Database	NAL-Catalogue (AGRICOLA)

In stock of ZB MED Bonn / Germany

Z 75/710: Show issues

Order via subito

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Details ▾
- See ZB MED holdings
- Order with fees

Article: Screening of protein-ligand interactions under crude conditions by native mass spectrometry

Takano, Kotaro / Arai, Shunsuke / Sakamoto, Seiji / Ushijima, Hiroshi / Ikegami, Takahisa / Saikusa, Kazumi / Konuma, Tsuyoshi / Hamachi, Itaru / Akashi, Satoko

Analytical and bioanalytical chemistry. 2020 July, v. 412, no. 17

2020

Abstract: A convenient analytical system for protein-ligand interactions under crude conditions was developed using native mass spectrometry (MS). As a model protein, Escherichia coli (E. coli) dihydrofolate reductase (DHFR) with and without a histidine tag was ... ...

Abstract	A convenient analytical system for protein-ligand interactions under crude conditions was developed using native mass spectrometry (MS). As a model protein, Escherichia coli (E. coli) dihydrofolate reductase (DHFR) with and without a histidine tag was used for the study. First, overexpressed DHFR with a His-tag was roughly purified with a Ni-sepharose resin and subjected to native mass spectrometry with or without incubation with an inhibitor, Methotrexate (MTX). Even only with the minimum cleanup by the Ni-sepharose resin, intact ions of DHFR-nicotinamide adenine dinucleotide phosphate (NADPH) and DHFR-NADPH-ligand complexes were successfully observed. By optimizing the preparation procedures of the crude sample for native MS, e.g., avoiding sonication for cell lysis, we successfully observed intact ions of the specific DHFR-NADPH-MTX ternary complex starting with cultivation of E. coli in ≤ 25 mL medium. When the crude DHFR sample was mixed with two, four, or eight candidate compounds, only ions of the specific protein-ligand complex were observed. This indicates that the present system can be used as a rapid and convenient method for the rough determination of binding of specific ligands to the target protein without the time-consuming purification of protein samples. Moreover, it is important to rapidly determine specific interactions with target proteins under conditions similar to those in “real” biological systems. Graphical abstract
Keywords	Escherichia coli ; adenine ; analytical chemistry ; dihydrofolate reductase ; histidine ; ligands ; mass spectrometry ; methotrexate ; phosphates ; sonication
Language	English
Dates of publication	2020-07
Size	p. 4037-4043.
Publishing place	Springer Berlin Heidelberg
Document type	Article
Note	NAL-AP-2-clean
ISSN	1618-2642
DOI	10.1007/s00216-020-02649-x
Database	NAL-Catalogue (AGRICOLA)

Order via subito

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article ; Online: Screening of protein-ligand interactions under crude conditions by native mass spectrometry.

Takano, Kotaro / Arai, Shunsuke / Sakamoto, Seiji / Ushijima, Hiroshi / Ikegami, Takahisa / Saikusa, Kazumi / Konuma, Tsuyoshi / Hamachi, Itaru / Akashi, Satoko

Analytical and bioanalytical chemistry

2020 Volume 412, Issue 17, Page(s) 4037–4043

Abstract	A convenient analytical system for protein-ligand interactions under crude conditions was developed using native mass spectrometry (MS). As a model protein, Escherichia coli (E. coli) dihydrofolate reductase (DHFR) with and without a histidine tag was used for the study. First, overexpressed DHFR with a His-tag was roughly purified with a Ni-sepharose resin and subjected to native mass spectrometry with or without incubation with an inhibitor, Methotrexate (MTX). Even only with the minimum cleanup by the Ni-sepharose resin, intact ions of DHFR-nicotinamide adenine dinucleotide phosphate (NADPH) and DHFR-NADPH-ligand complexes were successfully observed. By optimizing the preparation procedures of the crude sample for native MS, e.g., avoiding sonication for cell lysis, we successfully observed intact ions of the specific DHFR-NADPH-MTX ternary complex starting with cultivation of E. coli in ≤ 25 mL medium. When the crude DHFR sample was mixed with two, four, or eight candidate compounds, only ions of the specific protein-ligand complex were observed. This indicates that the present system can be used as a rapid and convenient method for the rough determination of binding of specific ligands to the target protein without the time-consuming purification of protein samples. Moreover, it is important to rapidly determine specific interactions with target proteins under conditions similar to those in "real" biological systems. Graphical abstract.
MeSH term(s)	Binding Sites ; Drug Evaluation, Preclinical/methods ; Escherichia coli/chemistry ; Escherichia coli/metabolism ; Escherichia coli Proteins/chemistry ; Escherichia coli Proteins/metabolism ; Folic Acid Antagonists/pharmacology ; Methotrexate/pharmacology ; NADP/chemistry ; NADP/metabolism ; Protein Binding ; Spectrometry, Mass, Electrospray Ionization/methods ; Tetrahydrofolate Dehydrogenase/chemistry ; Tetrahydrofolate Dehydrogenase/metabolism
Chemical Substances	Escherichia coli Proteins ; Folic Acid Antagonists ; NADP (53-59-8) ; Tetrahydrofolate Dehydrogenase (EC 1.5.1.3) ; Methotrexate (YL5FZ2Y5U1)
Language	English
Publishing date	2020-04-23
Publishing country	Germany
Document type	Journal Article
ZDB-ID	201093-8
ISSN	1618-2650 ; 0016-1152 ; 0372-7920
ISSN (online)	1618-2650
ISSN	0016-1152 ; 0372-7920
DOI	10.1007/s00216-020-02649-x
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Bonn / Germany

Z 4' 69/97: Show issues
Archiv 3: Show issues
Z 9.4: Show issues

Order via subito

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Details ▾
- See ZB MED holdings
- Order with fees

To top

More links

Kategorien

Order via subito

More links

Kategorien

In stock of ZB MED Bonn / Germany

Order via subito

Inter-library loan at ZB MED

Full text online

More links

Kategorien

Order via subito

More links

Kategorien

In stock of ZB MED Bonn / Germany

Order via subito

Inter-library loan at ZB MED

More links

Kategorien

In stock of ZB MED Bonn / Germany

Order via subito

Inter-library loan at ZB MED

Full text online

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

Full text online

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Bonn / Germany

Order via subito

Inter-library loan at ZB MED

More links

Kategorien

Order via subito

Inter-library loan at ZB MED

More links

Kategorien

In stock of ZB MED Bonn / Germany

Order via subito

Inter-library loan at ZB MED